Affiliation: Albert Einstein College of Medicine
- Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophagesMauricio Alvarez
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
BMC Immunol 8:16. 2007..In this report we have used time-lapse imaging to determine if this occurs with Cn...
- The outcome of Cryptococcus neoformans intracellular pathogenesis in human monocytesMauricio Alvarez
Department of Microbiology and Immunology and Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
BMC Microbiol 9:51. 2009..In this study we extended studies of C. neoformans-macrophage cellular interaction/s to human peripheral blood monocytes...
- The outcome of phagocytic cell division with infectious cargo depends on single phagosome formationYong Luo
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, United States of America
PLoS ONE 3:e3219. 2008..Post-mitotic infectious cargo distribution is a new parameter to consider in the study of intracellular pathogens since it could potentially define the outcome of phagocytic-microbial interactions...
- Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophagesMauricio Alvarez
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, 10461, USA
Curr Biol 16:2161-5. 2006....
- The relative susceptibility of mouse strains to pulmonary Cryptococcus neoformans infection is associated with pleiotropic differences in the immune responseOscar Zaragoza
Departments of Microbiology and Immunology and Medicine, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Infect Immun 75:2729-39. 2007....
- Antibody action after phagocytosis promotes Cryptococcus neoformans and Cryptococcus gattii macrophage exocytosis with biofilm-like microcolony formationMauricio Alvarez
Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
Cell Microbiol 10:1622-33. 2008..This finding suggests that antibody agglutination effects persist in the phagosome to entangle nascent daughter cells and this phenomenon may contribute to antibody-mediated protection...
- Phagocytosis of Cryptococcus neoformans by, and nonlytic exocytosis from, Acanthamoeba castellaniiCara J Chrisman
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Appl Environ Microbiol 76:6056-62. 2010..These results provide additional support for the notion that some mechanisms of virulence observed during mammalian infection originated, and were selected for, by environmental interactions...
- An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumoniaXiuping Shao
Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Immunol 175:3244-51. 2005..In summary, differences in AM function in rats and mice suggest an explanation for the species differences in susceptibility to C. neoformans based on the inherent efficacy of a central effector cell of the innate immune system...
- Structural and functional characterization of glycosylation in an immunoglobulin G1 to Cryptococcus neoformans glucuronoxylomannanFang Wang
Laboratory for Macromolecular Analysis and Proteomics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Mol Immunol 43:987-98. 2006..The results imply that the contribution of N-glycan structure to immunoglobulin function varies depending on the Ag-Ab system...
- Binding of the wheat germ lectin to Cryptococcus neoformans suggests an association of chitinlike structures with yeast budding and capsular glucuronoxylomannanMarcio L Rodrigues
Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, 21941590, RJ, Brazil
Eukaryot Cell 7:602-9. 2008..neoformans, which may represent a new mechanism by which the capsular polysaccharide interacts with the cell wall and is rearranged during replication...
- Vesicular polysaccharide export in Cryptococcus neoformans is a eukaryotic solution to the problem of fungal trans-cell wall transportMarcio L Rodrigues
Laboratorio de Estudos Integrados em Bioquimica Microbiana, Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941590, Brazil
Eukaryot Cell 6:48-59. 2007..The results imply a novel mechanism for the release of the major virulence factor of C. neoformans whereby polysaccharide packaged in lipid vesicles crosses the cell wall and the capsule network to reach the extracellular environment...