G Rock

Summary

Affiliation: University of Toronto

Publications

  1. doi request reprint Mechanism of microthrombosis in HUS
    Gail A Rock
    Canadian Apheresis Group, Ottawa, Ontario, Canada
    Kidney Int Suppl . 2009
  2. ncbi request reprint The development of an optimized autologous blood donation program
    G Rock
    Division of Hematology and Transfusion Medicine, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON, Canada
    Transfus Apher Sci 33:325-31. 2005
  3. ncbi request reprint Does cryosupernatant plasma improve outcome in thrombotic thrombocytopenic purpura? No answer yet
    Gail Rock
    Division of Hematology and Transfusion Medicine, Ottawa Civic Hospital, University of Ottawa, Ottawa, ON, Canada
    Br J Haematol 129:79-86. 2005
  4. ncbi request reprint Development of a total quality system for transfusion medicine services in Ontario hospitals
    G Rock
    Division of Hematology and Transfusion Medicine, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON, Canada
    Transfus Apher Sci 33:333-42. 2005
  5. ncbi request reprint Evaluation of platelet transfusion triggers in a tertiary-care hospital
    Bruce Cameron
    Division of Hematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada
    Transfusion 47:206-11. 2007
  6. ncbi request reprint ADAMTS-13 levels in fresh, stored, and solvent detergent treated plasma
    G Rock
    Department of Pathology and Laboratory Medicine, Division of Hematology and Transfusion Medicine, The Ottawa Hospital and University of Ottawa, Ottawa, Ont, Canada
    Transfus Apher Sci 35:235-8. 2006
  7. ncbi request reprint The contribution of platelets in the production of cryoprecipitates for use in a fibrin glue
    G Rock
    The University of Ottawa, Ottawa, ON, Canada
    Vox Sang 91:252-5. 2006
  8. ncbi request reprint Identification of plasma antifibrin/fibrinogen antibodies in a patient with hemolytic uremic syndrome
    Gail Rock
    Division of Hematology and Transfusion Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Blood Coagul Fibrinolysis 17:539-44. 2006
  9. ncbi request reprint A review of nearly two decades in an autologous blood programme: The rise and fall of activity
    G Rock
    University of Ottawa, Ottawa, ON, Canada
    Transfus Med 16:307-11. 2006
  10. ncbi request reprint The Canadian apheresis registry
    G Rock
    Transfus Apher Sci 29:167-77. 2003

Collaborators

Detail Information

Publications31

  1. doi request reprint Mechanism of microthrombosis in HUS
    Gail A Rock
    Canadian Apheresis Group, Ottawa, Ontario, Canada
    Kidney Int Suppl . 2009
    ..Although a direct cause-effect relationship is not yet established, the data support the concept of an immunological pathogenesis for HUS with the formation of cross-reacting antibodies...
  2. ncbi request reprint The development of an optimized autologous blood donation program
    G Rock
    Division of Hematology and Transfusion Medicine, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON, Canada
    Transfus Apher Sci 33:325-31. 2005
    ..Autologous blood (ABD) programs have been in place in Canada since the late 1980s. Activity is decreasing in many sites and utilization averages 50%...
  3. ncbi request reprint Does cryosupernatant plasma improve outcome in thrombotic thrombocytopenic purpura? No answer yet
    Gail Rock
    Division of Hematology and Transfusion Medicine, Ottawa Civic Hospital, University of Ottawa, Ottawa, ON, Canada
    Br J Haematol 129:79-86. 2005
    ..A large number of patients will be required to determine appropriate replacement therapy. We were not able to find a statistically significant relationship between the low level of protease activity at presentation of TTP and response...
  4. ncbi request reprint Development of a total quality system for transfusion medicine services in Ontario hospitals
    G Rock
    Division of Hematology and Transfusion Medicine, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, ON, Canada
    Transfus Apher Sci 33:333-42. 2005
    ..In Ottawa these activities resulted in the development of:..
  5. ncbi request reprint Evaluation of platelet transfusion triggers in a tertiary-care hospital
    Bruce Cameron
    Division of Hematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada
    Transfusion 47:206-11. 2007
    ..An analysis of patterns of utilization has been undertaken to evaluate practice...
  6. ncbi request reprint ADAMTS-13 levels in fresh, stored, and solvent detergent treated plasma
    G Rock
    Department of Pathology and Laboratory Medicine, Division of Hematology and Transfusion Medicine, The Ottawa Hospital and University of Ottawa, Ottawa, Ont, Canada
    Transfus Apher Sci 35:235-8. 2006
    ..As various methods are used to prepare plasma we determined the effects of storage and solvent detergent treatment on the ADAMTS-13 levels in plasma...
  7. ncbi request reprint The contribution of platelets in the production of cryoprecipitates for use in a fibrin glue
    G Rock
    The University of Ottawa, Ottawa, ON, Canada
    Vox Sang 91:252-5. 2006
    ..Cryoprecipitate has a wide application for use as a fibrin glue. In some situations, platelets are added to the preparation in order to enhance the fibrin glue...
  8. ncbi request reprint Identification of plasma antifibrin/fibrinogen antibodies in a patient with hemolytic uremic syndrome
    Gail Rock
    Division of Hematology and Transfusion Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Blood Coagul Fibrinolysis 17:539-44. 2006
    ..This patient's plasma contained a platelet-aggregating factor that was removed by immunoglobulin absorption. She developed antibodies against the alpha and beta subunits of fibrin/fibrinogen...
  9. ncbi request reprint A review of nearly two decades in an autologous blood programme: The rise and fall of activity
    G Rock
    University of Ottawa, Ottawa, ON, Canada
    Transfus Med 16:307-11. 2006
    ..The activity in the programme increased until 1996 following which it dropped progressively. The low haemoglobin concentration after surgery is of concern and should foster a transfusion algorithm for these patients...
  10. ncbi request reprint The Canadian apheresis registry
    G Rock
    Transfus Apher Sci 29:167-77. 2003
    ..Over the past 22 years, the activities of the CAG have lead to a rational, cost effective, use of TA in our country, have promoted the dissemination of knowledge among apheresis practitioners and have fostered optimal patient care...
  11. ncbi request reprint New methods showing in vitro changes of platelets
    G Rock
    Department of Pathology and Laboratory Medicine, University of Ottawa, Ont, Canada
    Transfus Apher Sci 35:145-9. 2006
    ..We used the ADVIA 120 and the Thromboelastogram (TEG) to assess changes during storage to determine a correlation of the results with those of other commonly used measures...
  12. ncbi request reprint Documenting a transfusion: how well is it done?
    Gail Rock
    Department of Pathology, and the Department of Epidemiology, University of Ottawa, Ottawa, Ontario, Canada
    Transfusion 47:568-72. 2007
    ..Current practice in transfusion medicine promotes clear documentation of transfusion-related events including the fact that the patient has been informed of the related risks and benefits...
  13. doi request reprint Analysis of the products of cryoprecipitation: RiCoF is deficient in cryosupernatant plasma
    M Freedman
    The Ottawa Hospital, Ottawa, ON, Canada
    Transfus Apher Sci 43:179-82. 2010
    ..In many instances, it is given to augment fresh frozen plasma when patients are bleeding. However, the full range of constituents of cryoprecipitate and CSP are not widely appreciated...
  14. ncbi request reprint Preparation and characterization of human thrombin for use in a fibrin glue
    G Rock
    Department of Pathology, University of Ottawa, Ottawa, Ontario, Canada
    Transfus Med 17:187-91. 2007
    ..This thrombin is in sufficient concentration to initiate clotting and cross-linking of fibrin from cryoprecipitate to produce an entirely autologous fibrin glue...
  15. doi request reprint Autologous blood programs: what is happening?
    G Rock
    Department of Pathology, The University of Ottawa, Canadian Apheresis Group, Suite 199, 435 St Laurent Boulevard, Ottawa, Ontario, Canada K1K 2Z8
    Transfus Apher Sci 39:193-7. 2008
    ..Such autologous programs have been both applauded and criticized in recent years with little information available regarding actual application...
  16. doi request reprint A comparison of methods of pathogen inactivation of FFP
    G Rock
    University of Ottawa, Ottawa, Ontario, Canada
    Vox Sang 100:169-78. 2011
    ..Three of these methods involve the use of visible or ultraviolet light...
  17. ncbi request reprint Automated collection of blood components: their storage and transfusion
    G Rock
    Department of Pathology and Laboratory Medicine, Ottawa Hospital and Canadian Blood Services, Ottawa, Ontario, Canada
    Transfus Med 13:219-25. 2003
    ..The platelets have good in vivo recovery, as shown by the CCI values. An added advantage is that the TRIMA machine can be used in hospitals to generate components in times of shortage without the need for a component's laboratory...
  18. ncbi request reprint The use of a bacteria detection system to evaluate bacterial contamination in PLT concentrates
    G Rock
    Department of Pathology and Laboratory Medicine, Division of Hematology and Transfusion Medicine, The Ottawa Hospital, 1053 Carling Avenue, Ottawa, Ontario K1Y 4E9, Canada
    Transfusion 44:337-42. 2004
    ..The ability of a bacteria detection system (BDS, Pall) to determine bacterial contamination and permit extension of the PLT shelf life to 7 days was assessed...
  19. ncbi request reprint A novel, automated method of temperature cycling to produce cryoprecipitate
    G Rock
    Ottawa Hospital Civic Campus and the Canadian Red Cross, Ottawa, Ontario, Canada
    Transfusion 41:232-5. 2001
    ..However, individual cryoprecipitates can vary greatly in content, with as many as 20 different factors known to affect the yield...
  20. ncbi request reprint Perceptions and motivations of Canadian autologous blood donors
    C Moltzan
    Departments of Laboratory Medicine, Medicine, and Psychiatry, University of Ottawa and Ottawa Hospital, Civic Campus, Ottawa, Ontario, Canada
    Transfus Med 11:177-82. 2001
    ..These perceptions and motivations must be taken into account as health care policy changes are considered...
  21. ncbi request reprint The supply of blood products in 10 different systems or countries
    G Rock
    Ottawa Hospital and University of Ottawa, c o Suite 101, 270 Sandridge Road, K1L 5A2, Ottawa, Ont, Canada
    Transfus Sci 22:171-82. 2000
    ..A series of specific questions were posed and the responses received from the various coauthors and other respondents provide comparative data on blood product availability in different areas of the world...
  22. ncbi request reprint Cryoprecipitate production: the use of additives to enhance the yield
    H Yousef
    Division of Hematology and Transfusion Medicine, Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada
    Clin Lab Haematol 28:237-40. 2006
    ..Assays showed considerable ranges in the quantity of FVIII and fibrinogen. Activation of FVIII can be caused by addition of excess calcium...
  23. doi request reprint ADAMTS-13 may not predict disease or outcome in patients with Thrombotic Thrombocytopenic Purpura
    G Rock
    Department of Pathology, University of Ottawa, Ottawa, ON, Canada
    Thromb Res 131:308-12. 2013
    ....
  24. ncbi request reprint Effects of different concentrations of anticoagulant on the in vitro characteristics of autologous whole blood
    N Cober
    Division of Hematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada
    Transfusion 41:1606-9. 2001
    ..CONCLUSION: Plasma Hb and plasma potassium concentrations are considerably higher in low-volume units, which indicates that deviation from standard collection procedures is deleterious to RBCs...
  25. ncbi request reprint Current perceptions of Canadian autologous blood donors
    M Banning
    Department of Psychology, The Ottawa Hospital, Ottawa, ON, Canada
    Vox Sang 91:157-61. 2006
    ..We determined the perceptions and motivations of autologous donors to establish their regard for this process and the new blood system established in 1999 in Canada...
  26. ncbi request reprint A pilot study to assess physician knowledge in transfusion medicine
    G Rock
    Department of Laboratory Medicine, Ottawa Hospital Civic Campus, Ontario, Canada
    Transfus Med 12:125-8. 2002
    ..An assessment of transfusion medicine knowledge and practice in Canada was carried out over a 3-week period...
  27. ncbi request reprint Changes in the Canadian blood system: the Krever Inquiry, Canadian Blood Services and Héma-Québec. Krever Commission
    G Rock
    University of Ottawa, Ont, Canada
    Transfus Sci 22:29-37. 2000
    ..Subsequently, in 1998, the Canadian Red Cross Society (CRC) withdrew from the blood program and two new organizations, the Canadian Blood Services (CBS) and Héma-Québec (HQ) took over as operators...
  28. ncbi request reprint Age of blood in inventory at a large tertiary care hospital
    W Owens
    Division of Hematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada
    Vox Sang 81:21-3. 2001
    ..Transfusion of large numbers of units of the same age and of a specific blood group and type may not always be possible...
  29. ncbi request reprint An in vitro method for predicting the efficacy of WBC separation using different starch preparations and anticoagulant ratios
    G Rock
    Division of Hematology and Transfusion Medicine, Ottawa Hospital, Civic Campus, Ottawa, Ontario, Canada
    Transfusion 40:1442-5. 2000
    ..A rapid in vitro approach was used to permit comparison of the efficiency of separation of WBCs by the use of PS and HP and different ratios of anticoagulants that also alter the sedimenting characteristics of blood...
  30. ncbi request reprint Feasibility of blinding in a randomized controlled trial comparing preoperative autologous blood donation and acute normovolemic hemodilution in adult cardiac surgery
    F D Rubens
    Departments of Surgery, Anaesthesia, and Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Transfusion 40:1058-62. 2000
    ..They have not, however, been compared to each other, because of perceived difficulties in blinding in such a clinical study. The feasibility of blinding was tested in a pilot trial...
  31. pmc Transfusion-transmitted malaria in Canada
    R Slinger
    Centre for Infectious Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ont
    CMAJ 164:377-9. 2001
    ..Although very rare, this diagnosis should be considered in transfusion recipients who have undiagnosed symptoms consistent with malaria. Thick and thin blood smears should be urgently examined to exclude this possibility...