Alberto Mantovani

Summary

Affiliation: Faculty of Medicine and Health Sciences
Country: United Arab Emirates

Publications

  1. pmc Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model
    Maria J Fernandez-Cabezudo
    Department of Biochemistry, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    PLoS ONE 8:e55993. 2013
  2. doi request reprint Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosis
    Basel K al-Ramadi
    Department of Microbiology and Immunology, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, United Arab Emirates
    Clin Immunol 130:89-97. 2009
  3. doi request reprint Attenuated bacteria as effectors in cancer immunotherapy
    Basel K al-Ramadi
    Department of Microbiology and Immunology, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    Ann N Y Acad Sci 1138:351-7. 2008
  4. ncbi request reprint CD154 is essential for protective immunity in experimental salmonella infection: evidence for a dual role in innate and adaptive immune responses
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, United Arab Emirates University
    J Immunol 176:496-506. 2006
  5. ncbi request reprint Selective induction of pentraxin 3, a soluble innate immune pattern recognition receptor, in infectious episodes in patients with haematological malignancy
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    Clin Immunol 112:221-4. 2004
  6. ncbi request reprint Poor survival but high immunogenicity of IL-2-expressing Salmonella typhimurium in inherently resistant mice
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE
    Microbes Infect 6:350-9. 2004
  7. ncbi request reprint Activation of innate immune responses by IL-2-expressing Salmonella typhimurium is independent of Toll-like receptor 4
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Mol Immunol 40:671-9. 2004
  8. ncbi request reprint Induction of innate immunity by IL-2-expressing Salmonella confers protection against lethal infection
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Mol Immunol 39:763-70. 2003
  9. ncbi request reprint Cytokine expression by attenuated intracellular bacteria regulates the immune response to infection: the Salmonella model
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, United Arab Emirates
    Mol Immunol 38:931-40. 2002
  10. ncbi request reprint The Src-protein tyrosine kinase Lck is required for IL-1-mediated costimulatory signaling in Th2 cells
    B K al-Ramadi
    Department of Medical Microbiology and Biochemistry, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    J Immunol 167:6827-33. 2001

Collaborators

Detail Information

Publications11

  1. pmc Intravenous administration of manuka honey inhibits tumor growth and improves host survival when used in combination with chemotherapy in a melanoma mouse model
    Maria J Fernandez-Cabezudo
    Department of Biochemistry, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    PLoS ONE 8:e55993. 2013
    ..This highlights a potentially novel role for manuka honey in alleviating chemotherapy-induced toxicity...
  2. doi request reprint Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosis
    Basel K al-Ramadi
    Department of Microbiology and Immunology, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, United Arab Emirates
    Clin Immunol 130:89-97. 2009
    ..This supports the notion of using cytokine-expressing attenuated Salmonella organisms in cancer therapy...
  3. doi request reprint Attenuated bacteria as effectors in cancer immunotherapy
    Basel K al-Ramadi
    Department of Microbiology and Immunology, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    Ann N Y Acad Sci 1138:351-7. 2008
    ..This supports the notion of using cytokine-expressing attenuated Salmonella organisms in cancer therapy...
  4. ncbi request reprint CD154 is essential for protective immunity in experimental salmonella infection: evidence for a dual role in innate and adaptive immune responses
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, United Arab Emirates University
    J Immunol 176:496-506. 2006
    ....
  5. ncbi request reprint Selective induction of pentraxin 3, a soluble innate immune pattern recognition receptor, in infectious episodes in patients with haematological malignancy
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    Clin Immunol 112:221-4. 2004
    ..2) but, surprisingly, was normal in 5/5 episodes of invasive aspergillosis (median 1.39). The data suggest that serum PTX3 levels are elevated selectively in response to infection. These disparate responses require further study...
  6. ncbi request reprint Poor survival but high immunogenicity of IL-2-expressing Salmonella typhimurium in inherently resistant mice
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE
    Microbes Infect 6:350-9. 2004
    ....
  7. ncbi request reprint Activation of innate immune responses by IL-2-expressing Salmonella typhimurium is independent of Toll-like receptor 4
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Mol Immunol 40:671-9. 2004
    ..Taken together, our data demonstrate that despite the induction of innate immune responses by IL2-expressing organisms, this was not sufficient to induce protection in TLR4 mutant mice...
  8. ncbi request reprint Induction of innate immunity by IL-2-expressing Salmonella confers protection against lethal infection
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Mol Immunol 39:763-70. 2003
    ..These findings highlight the importance of innate immunity in the control of early bacterial proliferation and demonstrate the rapidity by which these responses are induced following bacterial entry...
  9. ncbi request reprint Cytokine expression by attenuated intracellular bacteria regulates the immune response to infection: the Salmonella model
    Basel K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, P O Box 17666, Al Ain, United Arab Emirates
    Mol Immunol 38:931-40. 2002
    ..These findings may well have important consequences for the potential utilization of bacterial vector-encoded cytokines in immunoregulation in different disease settings...
  10. ncbi request reprint The Src-protein tyrosine kinase Lck is required for IL-1-mediated costimulatory signaling in Th2 cells
    B K al-Ramadi
    Department of Medical Microbiology and Biochemistry, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    J Immunol 167:6827-33. 2001
    ..These findings strongly suggest that Lck is required for signaling in the IL-1 costimulatory pathway in Th2 lymphocytes...
  11. pmc Influence of vector-encoded cytokines on anti-Salmonella immunity: divergent effects of interleukin-2 and tumor necrosis factor alpha
    B K al-Ramadi
    Department of Medical Microbiology, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates
    Infect Immun 69:3980-8. 2001
    ....