Paul Wark

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. ncbi request reprint Nebulised hypertonic saline for cystic fibrosis
    P A Wark
    Level D, Centre Block, University Medicine, Southampton General Hospital, Southampton, UK, SO16 6YD
    Cochrane Database Syst Rev . 2003
  2. ncbi request reprint DX-890 (Dyax)
    Peter A B Wark
    Southampton General Hospital, RCMB Research Division, Tremona Road, Southampton, SO16 6YD, UK
    IDrugs 5:586-9. 2002
  3. pmc Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
    Peter A B Wark
    The Brooke Laboratories, University of Southampton, Southampton SO16 6YD, UK
    J Exp Med 201:937-47. 2005
  4. ncbi request reprint Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment
    Peter Wark
    Brooke Laboratories, Southampton University, MP 810 Tremona Road, Southampton, UK
    Respir Med 98:915-23. 2004
  5. ncbi request reprint Drug treatment for chronic obstructive pulmonary disease
    Paul Wark
    University of Southampton, RCMB Centre Block Level D MP 810, Tremona Rd, Southampton, SO16 6YD, UK
    IDrugs 6:874-9. 2003
  6. ncbi request reprint IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations
    Peter A B Wark
    Brooke Laboratories, University of Southampton, Southampton, United Kingdom
    J Allergy Clin Immunol 120:586-93. 2007
  7. ncbi request reprint Clinical usefulness of inflammatory markers in asthma
    Peter A B Wark
    Research Division, Respiratory Cell and Molecular Biology, Southampton General Hospital, Southampton, UK
    Am J Respir Med 2:11-9. 2003
  8. ncbi request reprint Role of deficient type III interferon-lambda production in asthma exacerbations
    Marco Contoli
    Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, Norfolk Place, London W2 1PG, UK
    Nat Med 12:1023-6. 2006
  9. ncbi request reprint Induced sputum 8-isoprostane concentrations in inflammatory airway diseases
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2310, Australia
    Am J Respir Crit Care Med 171:426-30. 2005
  10. ncbi request reprint Use of induced sputum for the diagnosis of influenza and infections in asthma: a comparison of diagnostic techniques
    Jodie L Simpson
    Department of Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, Newcastle, New South Wales 2310, Australia
    J Clin Virol 26:339-46. 2003

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Nebulised hypertonic saline for cystic fibrosis
    P A Wark
    Level D, Centre Block, University Medicine, Southampton General Hospital, Southampton, UK, SO16 6YD
    Cochrane Database Syst Rev . 2003
    ..Hypertonic saline (HS) has been shown to enhance mucociliary clearance in-vitro and this may act to lessen the destructive inflammatory process in the airways...
  2. ncbi request reprint DX-890 (Dyax)
    Peter A B Wark
    Southampton General Hospital, RCMB Research Division, Tremona Road, Southampton, SO16 6YD, UK
    IDrugs 5:586-9. 2002
    ..In September 2000, JP Morgan predicted a 2005 launch for this drug, with estimated sales in that year of 23 US dollars million rising to 63 million US dollars in 2007 [397766]...
  3. pmc Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
    Peter A B Wark
    The Brooke Laboratories, University of Southampton, Southampton SO16 6YD, UK
    J Exp Med 201:937-47. 2005
    ..These data suggest a novel use for type I interferons in the treatment or prevention of virus-induced asthma exacerbations...
  4. ncbi request reprint Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment
    Peter Wark
    Brooke Laboratories, Southampton University, MP 810 Tremona Road, Southampton, UK
    Respir Med 98:915-23. 2004
    ..The aim of this review is to outline the pathogenesis of the disorder, diagnostic criteria and to discuss the use of anti-fungal agents in its treatment...
  5. ncbi request reprint Drug treatment for chronic obstructive pulmonary disease
    Paul Wark
    University of Southampton, RCMB Centre Block Level D MP 810, Tremona Rd, Southampton, SO16 6YD, UK
    IDrugs 6:874-9. 2003
    ....
  6. ncbi request reprint IFN-gamma-induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations
    Peter A B Wark
    Brooke Laboratories, University of Southampton, Southampton, United Kingdom
    J Allergy Clin Immunol 120:586-93. 2007
    ..Rhinovirus-induced acute asthma is the most frequent trigger for asthma exacerbations...
  7. ncbi request reprint Clinical usefulness of inflammatory markers in asthma
    Peter A B Wark
    Research Division, Respiratory Cell and Molecular Biology, Southampton General Hospital, Southampton, UK
    Am J Respir Med 2:11-9. 2003
    ..The place of induced sputum and eNO in the ongoing monitoring of patients with asthma are now being investigated in controlled trials...
  8. ncbi request reprint Role of deficient type III interferon-lambda production in asthma exacerbations
    Marco Contoli
    Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, Norfolk Place, London W2 1PG, UK
    Nat Med 12:1023-6. 2006
    ..These results identify previously unknown mechanisms of susceptibility to infection in asthma and suggest new approaches to prevention and/or treatment of asthma exacerbations...
  9. ncbi request reprint Induced sputum 8-isoprostane concentrations in inflammatory airway diseases
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2310, Australia
    Am J Respir Crit Care Med 171:426-30. 2005
    ..Analysis of 8-iso-PGF(2alpha) concentrations in induced sputum provides a useful tool for monitoring oxidative stress and investigating strategies aimed at reducing oxidative stress in airways disease...
  10. ncbi request reprint Use of induced sputum for the diagnosis of influenza and infections in asthma: a comparison of diagnostic techniques
    Jodie L Simpson
    Department of Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, Newcastle, New South Wales 2310, Australia
    J Clin Virol 26:339-46. 2003
    ..Sputum was assayed using IFA and RT-PCR for flu and RSV. Flu serology was performed acutely and at convalescence, 4-5 weeks later...