Claire S Waddington

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi request reprint The challenge of enteric fever
    Claire S Waddington
    Department of Paediatrics, University of Oxford, Children s Hospital, Oxford OX3 9DU, United Kingdom Electronic address
    J Infect 68:S38-50. 2014
  2. pmc Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study
    Claire S Waddington
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford OX3 7LJ
    BMJ 340:c2649. 2010
  3. pmc Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans
    Thomas C Darton
    Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, Department of Paediatrics, University of Oxford, and National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom
    PLoS Negl Trop Dis 9:e0004029. 2015
  4. doi request reprint Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies
    Claire S Waddington
    Oxford Vaccine Group, Department of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford OX3 7LJ, UK NIHR Oxford Biomedical Research Centre, The Joint Research Office, Block 60, The Churchill Hospital, Old Road, Headington, Oxford OX3 7LE, UK Electronic address
    J Infect 68:405-18. 2014
  5. doi request reprint Prospects for prevention of Salmonella infection in children through vaccination
    Alastair C McGregor
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, Oxford, UK
    Curr Opin Infect Dis 26:254-62. 2013
  6. pmc An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution
    Claire S Waddington
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford
    Clin Infect Dis 58:1230-40. 2014

Collaborators

Detail Information

Publications6

  1. doi request reprint The challenge of enteric fever
    Claire S Waddington
    Department of Paediatrics, University of Oxford, Children s Hospital, Oxford OX3 9DU, United Kingdom Electronic address
    J Infect 68:S38-50. 2014
    ..Human microbial infection studies could provide a vehicle for the rapid evaluation of novel vaccines and investigation of the immunobiology of enteric infection. ..
  2. pmc Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study
    Claire S Waddington
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford OX3 7LJ
    BMJ 340:c2649. 2010
    ..To compare the safety, reactogenicity, and immunogenicity of an adjuvanted split virion H1N1 vaccine and a non-adjuvanted whole virion vaccine used in the pandemic immunisation programme in the United Kingdom...
  3. pmc Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans
    Thomas C Darton
    Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, Department of Paediatrics, University of Oxford, and National Institute for Health Research Oxford Biomedical Research Centre, Oxford, United Kingdom
    PLoS Negl Trop Dis 9:e0004029. 2015
    ..Here, we investigate alterations in hepcidin and iron/inflammatory indices following experimental human typhoid challenge...
  4. doi request reprint Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies
    Claire S Waddington
    Oxford Vaccine Group, Department of Paediatrics, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford OX3 7LJ, UK NIHR Oxford Biomedical Research Centre, The Joint Research Office, Block 60, The Churchill Hospital, Old Road, Headington, Oxford OX3 7LE, UK Electronic address
    J Infect 68:405-18. 2014
    ....
  5. doi request reprint Prospects for prevention of Salmonella infection in children through vaccination
    Alastair C McGregor
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, Oxford, UK
    Curr Opin Infect Dis 26:254-62. 2013
    ..In this study we review recent progress in the development of vaccines against S. Typhi, S. Paratyphi and nontyphoidal Salmonella for children...
  6. pmc An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution
    Claire S Waddington
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford
    Clin Infect Dis 58:1230-40. 2014
    ..We set out to establish a new human challenge model and ascertain the S. Typhi (Quailes strain) inoculum required for an attack rate of 60%-75% in typhoid-naive volunteers when ingested with sodium bicarbonate solution...