Affiliation: University of Dundee
- Recovering from eccentric exercise: get weak to become strongHenning Wackerhage
Division of Molecular Physiology, School of Life Sciences, University of Dundee DD1 4HN, Scotland, UK
J Physiol 553:681. 2003
- Signal transduction pathways that regulate muscle growthHenning Wackerhage
Institute of Medical Sciences, Foresterhill, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, UK
Essays Biochem 44:99-108. 2008..The action of the mTOR system is opposed by myostatin-Smad signalling which inhibits muscle growth via gene transcription...
- Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscleDaniel Cuthbertson
Division of Molecular Physiology, School of Life Sciences, University of Dundee, Dundee, Scotland
FASEB J 19:422-4. 2005..Countermeasures to maximize muscle maintenance should target these deficits...
- 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy menDaniel J Cuthbertson
Department of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK
Diabetes 56:2078-84. 2007..3 +/- 0.6 to 10 +/- 0.6 mg x kg(-1) x min(-1) (P < 0.05). In healthy people, AICAR acutely stimulates muscle 2DG uptake with a minor effect on whole-body glucose disposal...
- Control of the size of the human muscle massMichael J Rennie
Division of Molecular Physiology, School of Life Sciences, University of Dundee, Dundee, DD1 4HN, Scotland, United Kingdom
Annu Rev Physiol 66:799-828. 2004....
- Connecting the dots for mechanochemical transduction in muscleMichael J Rennie
Division of Molecular Physiology, School of Life Sciences, University of Dundee, Dundee DD1 4HN, UK
J Physiol 553:1. 2003....
- Concentrations of signal transduction proteins exercise and insulin responses in rat extensor digitorum longus and soleus musclesPhilip J Atherton
Department of Biological Sciences, University of Central Lancashire, Preston, PR1 2HE, England, UK
Mol Cell Biochem 261:111-6. 2004..g. higher in larger fibres or slow muscle). Interindividual differences in fibre composition might explain variable responses to training and insulin...
- Branched-chain amino acids as fuels and anabolic signals in human muscleMichael J Rennie
Medical Sciences, University of Aberdeen, Aberdeen AB24 3FX, UK
J Nutr 136:264S-8S. 2006..However, at insulin of <5 microU/mL, AAs appear to stimulate MPS without increasing mTOR signaling. Further increasing availability of insulin to postprandial values increases signaling activity, but has no further effect on MPS...
- How nutrition and exercise maintain the human musculoskeletal massHenning Wackerhage
School of Medical Sciences, University of Aberdeen, UK
J Anat 208:451-8. 2006..Current evidence suggests that one of the major problems with loss of muscle during ageing is an inability of the tissue to respond adequately to increased availability of nutrients...
- Effect of psychological intervention on exercise adherence in type 2 diabetic subjectsRobert Martinus
Department of Biological, University of Central Lancashire, Preston, Lancashire, PR1 2HE UK
Ann N Y Acad Sci 1084:350-60. 2006..05). In conclusion, the results have demonstrated that psychological intervention is of paramount importance for ensuring high adherence rates during exercise therapy for type 2 diabetic subjects...
- Blockades of mitogen-activated protein kinase and calcineurin both change fibre-type markers in skeletal muscle cultureJames Higginson
Muscle Research Group, Department of Biological Sciences, University of Central Lancashire, Preston PR1 2HE, UK
Pflugers Arch 445:437-43. 2002..The effect of U0126 on the percentage of pyruvate dehydrogenase in the active form suggests that the ERK1/2 pathway may also be involved in regulation of the phosphorylation state of this enzyme...