O R Vaughan

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Maternal corticosterone regulates nutrient allocation to fetal growth in mice
    Owen R Vaughan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, Downing Street, Cambridge CB2 3EG, UK
    J Physiol 590:5529-40. 2012
  2. doi Environmental regulation of placental phenotype: implications for fetal growth
    O R Vaughan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
    Reprod Fertil Dev 24:80-96. 2011
  3. doi Placental-specific Igf2 deficiency alters developmental adaptations to undernutrition in mice
    A N Sferruzzi-Perri
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, United Kingdom
    Endocrinology 152:3202-12. 2011
  4. pmc Dietary composition programmes placental phenotype in mice
    P M Coan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
    J Physiol 589:3659-70. 2011
  5. pmc Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice
    P M Coan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
    J Physiol 588:527-38. 2010
  6. pmc Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy
    J S Higgins
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
    J Physiol 594:1341-56. 2016
  7. doi Review: Endocrine regulation of placental phenotype
    A L Fowden
    Centre for Trophoblast Research, Department of Physiology Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK Electronic address
    Placenta 36:S50-9. 2015
  8. pmc Corticosterone alters materno-fetal glucose partitioning and insulin signalling in pregnant mice
    O R Vaughan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK
    J Physiol 593:1307-21. 2015

Collaborators

Detail Information

Publications8

  1. pmc Maternal corticosterone regulates nutrient allocation to fetal growth in mice
    Owen R Vaughan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, Downing Street, Cambridge CB2 3EG, UK
    J Physiol 590:5529-40. 2012
    ..Maternal corticosterone is, therefore, a physiological regulator of the amino acid supply for fetal growth via actions on placental phenotype...
  2. doi Environmental regulation of placental phenotype: implications for fetal growth
    O R Vaughan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
    Reprod Fertil Dev 24:80-96. 2011
    ....
  3. doi Placental-specific Igf2 deficiency alters developmental adaptations to undernutrition in mice
    A N Sferruzzi-Perri
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, United Kingdom
    Endocrinology 152:3202-12. 2011
    ..Therefore, Igf2P0 plays important roles in adapting placental nutrient transfer capacity during UN, via actions directly on the placenta and/or indirectly through the mother...
  4. pmc Dietary composition programmes placental phenotype in mice
    P M Coan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
    J Physiol 589:3659-70. 2011
    ..This has important implications for the intrauterine programming of life expectancy...
  5. pmc Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice
    P M Coan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
    J Physiol 588:527-38. 2010
    ..Consequently, placental phenotype is responsive to environmental conditions and may help predict the risk of adult disease programmed in utero...
  6. pmc Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy
    J S Higgins
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
    J Physiol 594:1341-56. 2016
    ..This has implications for high altitude human pregnancies...
  7. doi Review: Endocrine regulation of placental phenotype
    A L Fowden
    Centre for Trophoblast Research, Department of Physiology Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK Electronic address
    Placenta 36:S50-9. 2015
    ..It focuses on the availability of placental hormone receptors and on the effects of hormones on the morphology, transport capacity and endocrine function of the placenta. ..
  8. pmc Corticosterone alters materno-fetal glucose partitioning and insulin signalling in pregnant mice
    O R Vaughan
    Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK
    J Physiol 593:1307-21. 2015
    ..Taken together, the data indicate that maternal glucocorticoid excess reduces fetal growth partially by altering placental glucose transport and mTOR signalling...