Jess Tyson

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc Determination of haplotypes at structurally complex regions using emulsion haplotype fusion PCR
    Jess Tyson
    School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    BMC Genomics 13:693. 2012
  2. pmc Quadruplex MAPH: improvement of throughput in high-resolution copy number screening
    Jess Tyson
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Genomics 10:453. 2009
  3. doi Screening for common copy-number variants in cancer genes
    Jess Tyson
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Cancer Genet Cytogenet 203:316-23. 2010
  4. pmc Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes
    Danielle Carpenter
    School of Life Sciences, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    Hum Mol Genet 24:3472-80. 2015
  5. pmc Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus
    Holly A Black
    School of Life Sciences, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Genomics 15:614. 2014
  6. ncbi Analysis of Multiallelic CNVs by Emulsion Haplotype Fusion PCR
    Jess Tyson
    School of Life Sciences, University of Nottingham Medical School, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    Methods Mol Biol 1492:155-165. 2017
  7. pmc Accurate measurement of gene copy number for human alpha-defensin DEFA1A3
    Fayeza F Khan
    School of Biology, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    BMC Genomics 14:719. 2013

Collaborators

Detail Information

Publications7

  1. pmc Determination of haplotypes at structurally complex regions using emulsion haplotype fusion PCR
    Jess Tyson
    School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    BMC Genomics 13:693. 2012
    ..This is turn means downstream determination of the true sequence haplotype in these regions poses a particular challenge. For structurally complex regions, a more focussed approach to assembling haplotypes may be required...
  2. pmc Quadruplex MAPH: improvement of throughput in high-resolution copy number screening
    Jess Tyson
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Genomics 10:453. 2009
    ..Copy number variation (CNV) in the human genome is recognised as a widespread and important source of human genetic variation. Now the challenge is to screen for these CNVs at high resolution in a reliable, accurate and cost-effective way...
  3. doi Screening for common copy-number variants in cancer genes
    Jess Tyson
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Cancer Genet Cytogenet 203:316-23. 2010
    ..However, this study has demonstrated a very low incidence of deletion and duplication variants within intronic and flanking regions of these nine genes, in both control individuals and colorectal cancer patients...
  4. pmc Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes
    Danielle Carpenter
    School of Life Sciences, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    Hum Mol Genet 24:3472-80. 2015
    ..Our results uncover new patterns in human amylase variation and imply a potential role for AMY2 CNV in functional associations. ..
  5. pmc Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus
    Holly A Black
    School of Life Sciences, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    BMC Genomics 15:614. 2014
    ....
  6. ncbi Analysis of Multiallelic CNVs by Emulsion Haplotype Fusion PCR
    Jess Tyson
    School of Life Sciences, University of Nottingham Medical School, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    Methods Mol Biol 1492:155-165. 2017
    ..In this description we outline the rationale for the application of emulsion-fusion PCR methods to the analysis of multiallelic CNVs, and give practical details for our own implementation of the method in that context...
  7. pmc Accurate measurement of gene copy number for human alpha-defensin DEFA1A3
    Fayeza F Khan
    School of Biology, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
    BMC Genomics 14:719. 2013
    ..The copy-variable alpha-defensin locus DEFA1A3 on human chromosome 8 commonly varies between 4 and 10 copies per diploid genome, and presents considerable challenges for accurate high-throughput typing...