- Single-chamber versus dual-chamber pacing for high-grade atrioventricular blockWilliam D Toff
Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, United Kingdom
N Engl J Med 353:145-55. 2005..Uncertainty persists regarding the true benefits of dual-chamber pacing, particularly in the elderly, in whom it is used less often than in younger patients...
- Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function, and endothelial activationWilliam D Toff
Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, England
JAMA 295:2251-61. 2006..It remains unclear whether the reduced cabin pressure and oxygen tension in the airplane cabin create an increased risk compared with seated immobility at ground level...
- Cardiovascular outcomes with atrial-based pacing compared with ventricular pacing: meta-analysis of randomized trials, using individual patient dataJeffrey S Healey
Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada, L8L 2X2
Circulation 114:11-7. 2006..No trial has shown a mortality reduction, and only 1 small trial suggested a reduction in stroke. The goal of this review was to determine whether atrial-based pacing prevents major cardiovascular events...