Amy E Taylor

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Is vulnerability to cardiometabolic disease in Indians mediated by abdominal adiposity or higher body adiposity
    Hannah Kuper
    Clinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Public Health 14:1239. 2014
  2. pmc Partner smoking and maternal cotinine during pregnancy: implications for negative control methods
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK Electronic address
    Drug Alcohol Depend 139:159-63. 2014
  3. pmc Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier
    A E Taylor
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    J Obes 2011:307542. 2011
  4. pmc Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK Electronic address
    Econ Hum Biol 13:99-106. 2014
  5. pmc Validation of dual energy X-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population
    Amy E Taylor
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e51042. 2012
  6. pmc IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children
    Amy E Taylor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Biol Psychiatry 70:152-8. 2011
  7. pmc Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, Bristol, United Kingdom UK Centre for Tobacco and Alcohol Research Studies, School of Experimental Psychology, University of Bristol, Bristol, United Kingdom
    PLoS Genet 10:e1004799. 2014
  8. pmc Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
    Richard W Morris
    School of Social and Community Medicine, University of Bristol, Bristol, UK Department of Primary Care and Population Health, UCL, London, UK
    BMJ Open 5:e008808. 2015
  9. pmc Investigating causality in the association between 25(OH)D and schizophrenia
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK
    Sci Rep 6:26496. 2016
  10. pmc Vitamin B-12 status during pregnancy and child's IQ at age 8: a Mendelian randomization study in the Avon longitudinal study of parents and children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e51084. 2012

Detail Information

Publications22

  1. pmc Is vulnerability to cardiometabolic disease in Indians mediated by abdominal adiposity or higher body adiposity
    Hannah Kuper
    Clinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Public Health 14:1239. 2014
    ....
  2. pmc Partner smoking and maternal cotinine during pregnancy: implications for negative control methods
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK Electronic address
    Drug Alcohol Depend 139:159-63. 2014
    ..However, this approach assumes that the effects of passive smoking from exposure to partner smoking during pregnancy are minimal. We evaluated this assumption using a biochemical measure of tobacco exposure in pregnant women...
  3. pmc Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier
    A E Taylor
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    J Obes 2011:307542. 2011
    ..03), but no evidence for effect modification by diet or physical activity. Further studies are needed to investigate ways in which urban environment may modify genetic risk of obesity...
  4. pmc Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK Electronic address
    Econ Hum Biol 13:99-106. 2014
    ..We illustrate these points with specific reference to tobacco research. ..
  5. pmc Validation of dual energy X-ray absorptiometry measures of abdominal fat by comparison with magnetic resonance imaging in an Indian population
    Amy E Taylor
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e51042. 2012
    ..DXA has not been fully validated for use in South Asians. Here, we determined the accuracy of DXA for measurement of abdominal fat in an Indian population by comparison with MRI...
  6. pmc IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children
    Amy E Taylor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Biol Psychiatry 70:152-8. 2011
    ..Although there is also evidence of milder cognitive impairment in later life in carriers of the APOE ε4 allele, there have been few studies investigating the impact of APOE genotype on cognitive function in children...
  7. pmc Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, Bristol, United Kingdom UK Centre for Tobacco and Alcohol Research Studies, School of Experimental Psychology, University of Bristol, Bristol, United Kingdom
    PLoS Genet 10:e1004799. 2014
    ..This demonstrates that novel associations may be obscured by hidden population sub-structure. Stratification on well-characterized environmental factors known to impact on health outcomes may therefore reveal novel genetic associations...
  8. pmc Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
    Richard W Morris
    School of Social and Community Medicine, University of Bristol, Bristol, UK Department of Primary Care and Population Health, UCL, London, UK
    BMJ Open 5:e008808. 2015
    ..To investigate, using a Mendelian randomisation approach, whether heavier smoking is associated with a range of regional adiposity phenotypes, in particular those related to abdominal adiposity...
  9. pmc Investigating causality in the association between 25(OH)D and schizophrenia
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK
    Sci Rep 6:26496. 2016
    ..These findings suggest that associations between schizophrenia and serum 25(OH)D may not be causal. Therefore, vitamin D supplementation may not prevent schizophrenia. ..
  10. pmc Vitamin B-12 status during pregnancy and child's IQ at age 8: a Mendelian randomization study in the Avon longitudinal study of parents and children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e51084. 2012
    ..Our findings suggest that maternal vitamin B-12 may not have an important effect on offspring cognitive ability. However, further examination of this issue is warranted...
  11. pmc What are the effects of varenicline compared with nicotine replacement therapy on long-term smoking cessation and clinically important outcomes? Protocol for a prospective cohort study
    Neil M Davies
    Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMJ Open 5:e009665. 2015
    ..In this study we aim to examine the effects of varenicline versus other smoking cessation pharmacotherapies on smoking cessation, health service use, all-cause and cause-specific mortality and physical and mental health conditions...
  12. pmc Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, Bristol, UK
    BMJ Open 4:e006141. 2014
    ..To investigate whether associations of smoking with depression and anxiety are likely to be causal, using a Mendelian randomisation approach...
  13. pmc Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK
    Sci Rep 5:14005. 2015
    ..Our results suggest that associations of alcohol consumption with blood pressure and HDL-cholesterol are causal. Alcohol also appeared to have adverse effects on triglyceride levels, although this may be restricted to diabetics. ..
  14. pmc Triangulating meta-analyses: the example of the serotonin transporter gene, stressful life events and major depression
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, Bristol, UK
    BMC Psychol 4:23. 2016
    ....
  15. pmc The CHRNA5-A3-B4 Gene Cluster and Smoking: From Discovery to Therapeutics
    Glenda Lassi
    UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, Bristol, UK Oncology Translational Medicine Unit, Early Clinical Development, AstraZeneca, Cambridge, UK Electronic address
    Trends Neurosci 39:851-861. 2016
    ..Validated targets can inform genetic therapeutic interventions for smoking cessation and tobacco-related diseases...
  16. pmc Life-course determinants of bone mass in young adults from a transitional rural community in India: the Andhra Pradesh Children and Parents Study (APCAPS)
    Mika Matsuzaki
    From the Departments of Non communicable Disease Epidemiology MM, RS, SE, and SK, the Department of Medical Statistics GBP, and Clinical Research HK, London School of Hygiene and Tropical Medicine, London, United Kingdom the Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia BK the National Institute of Nutrition, Hyderabad, India BK and KVR the Musculoskeletal Research Unit, School of Clinical Sciences HV and JHT and the School of Social and Community Medicine AET, YB S, and GDS, University of Bristol, Bristol, United Kingdom St George s University, London, United Kingdom LB the Childhood Nutrition Research Centre, UCL Institute of Child Health, London, United Kingdom JCW the Centre for Chronic Disease Control, New Delhi, India DP and the South Asia Network for Chronic Disease, Public Health Foundation of India, New Delhi, India SE
    Am J Clin Nutr 99:1450-9. 2014
    ..Undernutrition and physical inactivity are both associated with lower bone mass...
  17. pmc Phenotype refinement strengthens the association of AHR and CYP1A1 genotype with caffeine consumption
    George McMahon
    Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 9:e103448. 2014
    ..Future studies may therefore be able to use this combined allelic score to explore causal effects of habitual caffeine consumption on health outcomes. ..
  18. pmc Maternal smoking during pregnancy and offspring smoking initiation: assessing the role of intrauterine exposure
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, Bristol, UK
    Addiction 109:1013-21. 2014
    ..To assess whether associations between maternal smoking during pregnancy and offspring smoking initiation are due to intrauterine mechanisms...
  19. doi request reprint Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts
    Amy E Taylor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Clin Nutr 91:547-56. 2010
    ..Measures of regional adiposity have been proposed as alternatives to the measurement of body mass index (BMI) for identifying persons at risk of future disease...
  20. pmc The Association of Cigarette Smoking With Depression and Anxiety: A Systematic Review
    Meg Fluharty
    MRC Integrative Epidemiology Unit IEU, University of Bristol, Bristol, United Kingdom
    Nicotine Tob Res 19:3-13. 2017
    ..However, the literature remains mixed regarding the direction of this association. We therefore conducted a systematic review evaluating the association of smoking and depression and/or anxiety in longitudinal studies...
  21. pmc Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis
    Amy E Taylor
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, Bristol, United Kingdom
    Int J Cancer 140:322-328. 2017
    ..03, 95% CI: 0.98,1.08). These results, which should have less bias from confounding than observational estimates, are not consistent with a substantial effect of coffee consumption on reducing prostate cancer incidence or progression...
  22. pmc Investigating causality in associations between smoking initiation and schizophrenia using Mendelian randomization
    Suzanne H Gage
    MRC Integrative Epidemiology Unit IEU at the University of Bristol, Bristol, UK
    Sci Rep 7:40653. 2017
    ..However, we cannot rule out a causal effect of smoking on schizophrenia related to heavier, lifetime exposure, rather than initiation...