Josephine K Swanton
Affiliation: University College London
- Is the frequency of abnormalities on magnetic resonance imaging in isolated optic neuritis related to the prevalence of multiple sclerosis? A global comparisonJ K Swanton
NMR Research Unit, Institute of Neurology, University College London, Queen Square, London, UK
J Neurol Neurosurg Psychiatry 77:1070-2. 2006..These observations may support the hypothesis that optic neuritis is more likely to be associated with abnormalities on MRI and to be due to multiple sclerosis in geographical regions where multiple sclerosis is more common...
- Early prognosis of multiple sclerosisJosephine Swanton
NMR Research Unit, Institute of Neurology, London, UK Electronic address
Handb Clin Neurol 122:371-91. 2014..This chapter reviews the current evidence, taken from both clinical and paraclinical sources, as it relates to establishing this prognosis and provides insight to where, in the future, we need to look. ..
- Early MRI in optic neuritis: the risk for disabilityJ K Swanton
NMR Unit, Institute of Neurology, Queen Square, London WC1N 3BG, UK
Neurology 72:542-50. 2009..MRI findings influence the risk of patients with optic neuritis (ON) developing clinically definite (CD) multiple sclerosis (MS) but their influence on future disability is less clear...
- MRI criteria for multiple sclerosis in patients presenting with clinically isolated syndromes: a multicentre retrospective studyJosephine K Swanton
Nuclear Magnetic Resonance Research Unit, Department of Neuroinflammation and Headache, Institute of Neurology, University College London, London, UK
Lancet Neurol 6:677-86. 2007..We applied all three criteria in a large cohort of CIS patients to assess their performance by use of conversion to clinically definite multiple sclerosis (CDMS) as the outcome...
- Early MRI in optic neuritis: the risk for clinically definite multiple sclerosisJ K Swanton
Department of Neuroinflammation and NMR Research Unit, UCL Institute of Neurology, London, UK
Mult Scler 16:156-65. 2010..1, 2.4 and 4.9, respectively). No non-conventional measure predicted CDMS. It was concluded that new T2 lesions on an early follow-up scan were the strongest independent predictor of CDMS...
- Magnetization transfer histograms in clinically isolated syndromes suggestive of multiple sclerosisK T M Fernando
NMR Research Unit, Institute of Neurology, King s College, London, UK
Brain 128:2911-25. 2005..MTR abnormalities occur in the NAWM and NAGM at the earliest clinical stages of multiple sclerosis...
- Texture analysis of magnetization transfer maps from patients with clinically isolated syndrome and multiple sclerosisD J Tozer
UCL Institute of Neurology, London, UK
J Magn Reson Imaging 30:506-13. 2009..To investigate the behavior of texture parameters derived from the gray level co-occurrence matrix from gray matter (GM) and white matter (WM) (with lesions removed) segments of magnetization transfer ratio maps from controls and patients...
- Should the symptomatic region be included in dissemination in space in MRI criteria for MS?Wallace J Brownlee
From the Queen Square Multiple Sclerosis Centre W J B, J K S, D H M, O C, Department of Neuroinflammation, UCL Institute of Neurology, London Lysholm Department of Neuroradiology K A M, National Hospital for Neurology and Neurosurgery, London and NIHR University College London Hospitals Biomedical Research Centre D H M, O C, London, UK
Neurology 87:680-3. 2016....
- Changing associations between cognitive impairment and imaging in multiple sclerosis as the disease progressesSophia A Penny
UCL Institute of Neurology, Queen Square, London, UK
J Neuropsychiatry Clin Neurosci 25:134-40. 2013..Our findings suggest that gray-matter pathology, reflected by atrophy measurements, becomes increasingly important in determining cognition as MS progresses...
- Selective magnetization transfer ratio decrease in the visual cortex following optic neuritisBertrand Audoin
NMR Research Unit, Department of Neuroinflammation, Institute of Neurology, University College London, London, UK
Brain 129:1031-9. 2006....
- Modification of MRI criteria for multiple sclerosis in patients with clinically isolated syndromesJ K Swanton
NMR Research Unit, 6th Floor, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
J Neurol Neurosurg Psychiatry 77:830-3. 2006..Although a major advance, the criteria have limited sensitivity for making an early diagnosis...