A W Stoker

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis
    Hamid Hashemi
    UCL Institute of Child Health, University College London, London, UK
    Mol Cell Neurosci 46:469-82. 2011
  2. ncbi request reprint Receptor tyrosine phosphatases in axon growth and guidance
    A W Stoker
    Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Curr Opin Neurobiol 11:95-102. 2001
  3. ncbi request reprint Methods for identifying extracellular ligands of RPTPs
    Andrew Stoker
    Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Methods 35:80-9. 2005
  4. ncbi request reprint Protein tyrosine phosphatases and signalling
    Andrew W Stoker
    Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    J Endocrinol 185:19-33. 2005
  5. pmc Dimerization of protein tyrosine phosphatase sigma governs both ligand binding and isoform specificity
    Simon Lee
    Neural Development Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
    Mol Cell Biol 27:1795-808. 2007
  6. pmc Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma
    A Radu Aricescu
    Neural Development Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
    Mol Cell Biol 22:1881-92. 2002
  7. ncbi request reprint Isoform-specific binding of the tyrosine phosphatase PTPsigma to a ligand in developing muscle
    Gustavo Sajnani-Perez
    Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Mol Cell Neurosci 22:37-48. 2003
  8. pmc Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-sigma
    Daniel E Alete
    Neural Development Unit, Institute of Child Health, University College London, UK
    FEBS J 273:4668-81. 2006
  9. ncbi request reprint Receptor tyrosine phosphatases guide vertebrate motor axons during development
    Laurie Stepanek
    Neuroscience Program, Miami Project to Cure Paralysis, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Neurosci 25:3813-23. 2005

Collaborators

  • John K Chilton
  • Hamid Hashemi
  • A Radu Aricescu
  • Simon Lee
  • Muhamed Hawadle
  • Daniel E Alete
  • Laurie Stepanek
  • Gustavo Sajnani-Perez
  • Veera Panova
  • Alastair Barr
  • Michael Hurley
  • Anna Gibson
  • Viktoria Tchetchelnitski
  • Daniel Alete
  • Clare Faux
  • Jennifer Nixon
  • Ara G Hovanession
  • Mark E Weeks
  • John L Bixby
  • Esther Stoeckli
  • Fawaz Haj
  • Willi Halfter
  • Iain W McKinnell

Detail Information

Publications9

  1. pmc Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis
    Hamid Hashemi
    UCL Institute of Child Health, University College London, London, UK
    Mol Cell Neurosci 46:469-82. 2011
    ..PTPγ therefore regulates neurogenesis during a window of spinal cord development, with molecular targets most likely related to Wnt/β-catenin signalling, cell survival and cell adhesion...
  2. ncbi request reprint Receptor tyrosine phosphatases in axon growth and guidance
    A W Stoker
    Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Curr Opin Neurobiol 11:95-102. 2001
    ..Vertebrate RPTPs are now implicated in controlling axon outgrowth, and preliminary evidence suggests that they too may influence axon guidance...
  3. ncbi request reprint Methods for identifying extracellular ligands of RPTPs
    Andrew Stoker
    Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Methods 35:80-9. 2005
    ..We provide troubleshooting details for RAP in situ and describe some other complementary techniques that can be used...
  4. ncbi request reprint Protein tyrosine phosphatases and signalling
    Andrew W Stoker
    Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    J Endocrinol 185:19-33. 2005
    ..It will be seen that PTPs control diverse processes such as focal adhesion dynamics, cell-cell adhesion and insulin signalling, and their own actions are in turn regulated by dimerisation, phosphorylation and reversible oxidation...
  5. pmc Dimerization of protein tyrosine phosphatase sigma governs both ligand binding and isoform specificity
    Simon Lee
    Neural Development Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
    Mol Cell Biol 27:1795-808. 2007
    ..These findings have important implications for our understanding of how heterophilic ligands interact with, and potentially regulate, RPTPs...
  6. pmc Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma
    A Radu Aricescu
    Neural Development Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, United Kingdom
    Mol Cell Biol 22:1881-92. 2002
    ..HSPGs are therefore a novel class of heterotypic ligand for cPTPsigma, suggesting that cPTPsigma signaling in axons and growth cones is directly responsive to matrix-associated cues...
  7. ncbi request reprint Isoform-specific binding of the tyrosine phosphatase PTPsigma to a ligand in developing muscle
    Gustavo Sajnani-Perez
    Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Mol Cell Neurosci 22:37-48. 2003
    ..The expression of cPTPsigma1 in motor axons and its direct binding to target myotubes suggest an isoform-specific role for axonally expressed cPTPsigma1 during establishment or maintenance of neuromuscular contacts...
  8. pmc Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-sigma
    Daniel E Alete
    Neural Development Unit, Institute of Child Health, University College London, UK
    FEBS J 273:4668-81. 2006
    ....
  9. ncbi request reprint Receptor tyrosine phosphatases guide vertebrate motor axons during development
    Laurie Stepanek
    Neuroscience Program, Miami Project to Cure Paralysis, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Neurosci 25:3813-23. 2005
    ..Our results indicate that RPTPs, and especially PTPRO, are required for axon growth and guidance in the developing vertebrate limb...