Janet Stocks

Summary

Affiliation: University College London
Country: UK

Publications

  1. doi request reprint How to avoid misinterpreting lung function tests in children: a few practical tips
    Janet Stocks
    Portex Respiratory Unit, UCL, Institute of Child Health, London, UK Electronic address
    Paediatr Respir Rev 15:170-80. 2014
  2. doi request reprint Early lung development: lifelong effect on respiratory health and disease
    Janet Stocks
    University College London, Institute of Child Health, London, UK Electronic address
    Lancet Respir Med 1:728-42. 2013
  3. pmc Early life influences on the development of chronic obstructive pulmonary disease
    Janet Stocks
    Portex Unit, University College London Institute of Child Health, 30, Guilford Street, London WC1N 1EH, UK
    Ther Adv Respir Dis 7:161-73. 2013
  4. doi request reprint Evaluation and use of childhood lung function tests in cystic fibrosis
    Janet Stocks
    UCL Institute of Child Health and Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Curr Opin Pulm Med 18:602-8. 2012
  5. doi request reprint Age and height dependence of lung clearance index and functional residual capacity
    Sooky Lum
    Portex Respiratory Unit, UCL Institute of Child Health, London, UK
    Eur Respir J 41:1371-7. 2013
  6. ncbi request reprint Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 171:249-56. 2005
  7. doi request reprint Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis
    Wanda J Kozlowska
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 178:42-9. 2008
  8. doi request reprint Repeatability and bronchodilator reversibility of lung function in young children
    Samatha Sonnappa
    Portex Unit, Respiratory Medicine and Physiology, UCL Institute of Child Health, London, UK
    Eur Respir J 42:116-24. 2013
  9. pmc Lung function and respiratory symptoms at 11 years in children born extremely preterm: the EPICure study
    Joseph Fawke
    Portex Unit Respiratory Physiology and Medicine, UCL, Institute of Child Health, WC1N 1EH London, UK
    Am J Respir Crit Care Med 182:237-45. 2010
  10. ncbi request reprint The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis
    Sarath C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:928-33. 2004

Detail Information

Publications53

  1. doi request reprint How to avoid misinterpreting lung function tests in children: a few practical tips
    Janet Stocks
    Portex Respiratory Unit, UCL, Institute of Child Health, London, UK Electronic address
    Paediatr Respir Rev 15:170-80. 2014
    ....
  2. doi request reprint Early lung development: lifelong effect on respiratory health and disease
    Janet Stocks
    University College London, Institute of Child Health, London, UK Electronic address
    Lancet Respir Med 1:728-42. 2013
    ..We focus particularly on asthma and COPD. ..
  3. pmc Early life influences on the development of chronic obstructive pulmonary disease
    Janet Stocks
    Portex Unit, University College London Institute of Child Health, 30, Guilford Street, London WC1N 1EH, UK
    Ther Adv Respir Dis 7:161-73. 2013
    ..This review focuses on factors that adversely influence lung development in utero and during the first 5 years of life, thereby predisposing to subsequent COPD...
  4. doi request reprint Evaluation and use of childhood lung function tests in cystic fibrosis
    Janet Stocks
    UCL Institute of Child Health and Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Curr Opin Pulm Med 18:602-8. 2012
    ..This article reviews lung function tests that can be used during the first 5 years of life and discusses their potential applications as objective outcomes for clinical monitoring or research...
  5. doi request reprint Age and height dependence of lung clearance index and functional residual capacity
    Sooky Lum
    Portex Respiratory Unit, UCL Institute of Child Health, London, UK
    Eur Respir J 41:1371-7. 2013
    ..Although a constant upper normal limit would suffice for cross-sectional clinical assessments from 6 years of age, appropriate reference equations are essential for accurate interpretation of results during early childhood...
  6. ncbi request reprint Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 171:249-56. 2005
    ..Most preschool children can perform multiple-breath washout, plethysmography, and spirometry at first attempt. Multiple-breath washout detects abnormal lung function in children with CF more readily than plethysmography or spirometry...
  7. doi request reprint Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis
    Wanda J Kozlowska
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 178:42-9. 2008
    ..After recent standardization of forced expiratory maneuvers for both infants and preschool children, longitudinal measurements are now possible from birth...
  8. doi request reprint Repeatability and bronchodilator reversibility of lung function in young children
    Samatha Sonnappa
    Portex Unit, Respiratory Medicine and Physiology, UCL Institute of Child Health, London, UK
    Eur Respir J 42:116-24. 2013
    ..These findings will help to interpret the effect of therapeutic interventions in children with respiratory diseases. ..
  9. pmc Lung function and respiratory symptoms at 11 years in children born extremely preterm: the EPICure study
    Joseph Fawke
    Portex Unit Respiratory Physiology and Medicine, UCL, Institute of Child Health, WC1N 1EH London, UK
    Am J Respir Crit Care Med 182:237-45. 2010
    ..The long-term respiratory sequelae of infants born extremely preterm (EP) and now graduating from neonatal intensive care remains uncertain...
  10. ncbi request reprint The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis
    Sarath C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:928-33. 2004
    ..5) of 20% (11, 28). Airway function is diminished soon after diagnosis in infants with CF and does not catch up during infancy and early childhood. These findings have important implications for early interventions in CF...
  11. ncbi request reprint Lung function tests in neonates and infants with chronic lung disease: forced expiratory maneuvers
    Sooky Lum
    Portex Respiratory Unit, Institute Institute of Child Health, London, UK
    Pediatr Pulmonol 41:199-214. 2006
    ....
  12. ncbi request reprint Lung function tests in neonates and infants with chronic lung disease of infancy: functional residual capacity
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service NHS Trust, London, UK
    Pediatr Pulmonol 41:1-22. 2006
    ..Although lung volume measurements in extremely preterm infants were described in a research environment, resolution of several issues is required before such investigations can be translated into routine clinical monitoring...
  13. doi request reprint Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, UCL Institute of Child Health, 30 Guilford St, London WC1N 1EH, UK
    Am J Respir Crit Care Med 183:752-8. 2011
    ..There is an urgent need for alternative surrogates that detect early lung disease and track through early childhood...
  14. pmc Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests
    Sooky Lum
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Thorax 62:341-7. 2007
    ....
  15. doi request reprint New reference equations to improve interpretation of infant lung function
    The Thanh Diem Nguyen
    Portex Respiratory Unit, UCL Institute of Child Health and Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Pediatr Pulmonol 48:370-80. 2013
    ..With increasing use of infant pulmonary function tests (IPFTs) in both clinical and research studies, appropriate interpretation of results is essential...
  16. doi request reprint Potential misinterpretation of infant lung function unless prospective healthy controls are studied
    Sooky Lum
    Portex Unit, Respiratory Physiology and Medicine, UCL, Institute of Child Health, London, UK
    Pediatr Pulmonol 45:906-13. 2010
    ..SUMMARY RATIONALE: Reliable interpretation of pulmonary function tests relies on appropriate reference data, which remain very limited for infants...
  17. doi request reprint Spirometry centile charts for young Caucasian children: the Asthma UK Collaborative Initiative
    Sanja Stanojevic
    Portex Unit, Respiratory Physiology and Medicine, UCL, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 180:547-52. 2009
    ....
  18. ncbi request reprint Quality control for spirometry in preschool children with and without lung disease
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:1152-9. 2004
    ..We describe recommendations for modified start of test and repeatability criteria for this age group, and for improvements in software to facilitate better quality control...
  19. pmc Lung function in children in relation to ethnicity, physique and socioeconomic factors
    Sooky Lum
    Respiratory, Critical Care and Anaesthesia Section in IIIP Programme, UCL Institute of Child Health, London, UK
    Eur Respir J 46:1662-71. 2015
    ....
  20. ncbi request reprint Development of lung function in early life: influence of birth weight in infants of nonsmokers
    Ah Fong Hoo
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 170:527-33. 2004
    ..These findings suggest that lung function is reduced in low birth weight for gestation infants born to nonsmoking white mothers and that this is independent of somatic growth during infancy...
  21. ncbi request reprint Respiratory physiotherapy vs. suction: the effects on respiratory function in ventilated infants and children
    Eleanor Main
    Centre for Nursing and Allied Health Professionals Research, Institute of Child Health, London and Physiotherapy Department, Great Ormond Street Hospital for Children NHS Trust, London WCIN 3JH, UK
    Intensive Care Med 30:1144-51. 2004
    ..To assess and compare the effects of physiotherapy and suction on expired tidal volume (V(TE)), respiratory compliance (C(rs)), resistance (R(rs)) and arterial blood gases...
  22. doi request reprint Lung Clearance Index and HRCT are complementary markers of lung abnormalities in young children with CF
    C M Owens
    Department of Paediatric Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Thorax 66:481-8. 2011
    ....
  23. pmc Is chest CT useful in newborn screened infants with cystic fibrosis at 1 year of age?
    Lena P Thia
    Portex Unit Respiratory Physiology and Medicine, UCL Institute of Child Health, London, UK
    Thorax 69:320-7. 2014
    ..Chest CT has been advocated as such a measure yet there is no validated scoring system in infants...
  24. doi request reprint The EPICure study: maximal exercise and physical activity in school children born extremely preterm
    Liam Welsh
    Portex Unit Respiratory Medicine and Physiology, UCL, Institute of Child Health, London, UK
    Thorax 65:165-72. 2010
    ..Since survivors remain at high risk for developing bronchopulmonary dysplasia (BPD) and long-term pulmonary sequelae, reductions in exercise capacity and activity levels may be present...
  25. doi request reprint The unique contribution of manual chest compression-vibrations to airflow during physiotherapy in sedated, fully ventilated children
    Rachael K Gregson
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health and Physiotherapy Department, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Crit Care Med 13:e97-e102. 2012
    ....
  26. doi request reprint Abbreviated multi-breath washout for calculation of lung clearance index
    Paul D Robinson
    Portex Respiratory Unit, UCL Institute of Child Health, London
    Pediatr Pulmonol 48:336-43. 2013
    ..Adult guidelines recommend three technically acceptable tests with FRC values within 10%, whilst preschool guidelines recommend two such tests. Feasibility of and need for recommendations in children is unclear...
  27. ncbi request reprint Lung function in infants and young children with chronic lung disease of infancy: the next steps?
    Janet Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Pulmonol 42:3-9. 2007
    ....
  28. doi request reprint Airway function in infants treated with inhaled nitric oxide for persistent pulmonary hypertension
    Aparna U Hoskote
    Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Pulmonol 43:224-35. 2008
    ....
  29. doi request reprint Ethnic differences in fraction of exhaled nitric oxide and lung function in healthy young children
    Samatha Sonnappa
    Portex Unit Respiratory Medicine and Physiology, University College of London Institute of Child Health and Great Ormond Street Hospital for Children, 30, Guilford St, London, WC1N 1EH, England
    Chest 140:1325-31. 2011
    ....
  30. pmc How "healthy" should children be when selecting reference samples for spirometry?
    Sooky Lum
    Respiratory, Critical Care and Anaesthesia Section Portex Unit, University College London, Institute of Child Health, London, UK
    Eur Respir J 45:1576-81. 2015
    ..With the exception of clear-cut factors, such as current and chronic respiratory disease, paediatric reference samples for spirometry can be relatively inclusive and hence more generalisable to the target population. ..
  31. ncbi request reprint Limitations of electronic compensation for measuring plethysmographic airway resistance in infants
    Padmaja Subbarao
    Portex Respiratory Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Pulmonol 40:45-52. 2005
    ..The marked within- and between-subject variability in healthy infants, and lack of discriminative power of R(aw) when derived from electronically compensated values, currently preclude application in either clinical or research studies...
  32. ncbi request reprint Partitioning of airway and parenchymal mechanics in unsedated newborn infants
    J Jane Pillow
    Portex Unit, Respiratory Physiology, Institue of Child Health, and Neonatal Unit, University College London Hospital, UK
    Pediatr Res 58:1210-5. 2005
    ..Measurements of lung function are feasible in the unsedated newborn infant using low-frequency forced oscillations and confirm the important contribution of tissue resistance to lung mechanics in the developing lung...
  33. doi request reprint Respiratory function during infancy in survivors of the INNOVO trial
    Ah Fong Hoo
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, London, UK
    Pediatr Pulmonol 44:155-61. 2009
    ..Furthermore, results were compared to lung function of healthy infants...
  34. pmc Natural variability of lung function in young healthy school children
    Jane Kirkby
    Respiratory, Critical Care and Anaesthesia section in Portex Unit, University College London, Institute of Child Health, London, UK Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Eur Respir J 48:411-9. 2016
    ..These must be considered when interpreting results from annual reviews in those with lung disease who are otherwise stable, if unnecessary further investigations or changes in treatment are to be avoided. ..
  35. pmc Challenges in Collating Spirometry Reference Data for South-Asian Children: An Observational Study
    Sooky Lum
    Respiratory, Critical Care and Anaesthesia Section Portex Unit, UCL, Institute of Child Health, London, United Kingdom
    PLoS ONE 11:e0154336. 2016
    ..Spirometry datasets from South-Asian children were collated from four centres in India and five within the UK. Records with transcription errors, missing values for height or spirometry, and implausible values were excluded(n = 110)...
  36. doi request reprint New reference ranges for interpreting forced expiratory manoeuvres in infants and implications for clinical interpretation: a multicentre collaboration
    Sooky Lum
    Respiratory, Critical Care and Anaesthesia Section in IIIP Programme, UCL, Institute of Child Health, London, UK
    Thorax 71:276-83. 2016
    ....
  37. doi request reprint Differences in delivery of respiratory treatments by on-call physiotherapists in mechanically ventilated children: a randomised crossover trial
    Harriet Shannon
    Physiotherapy Section in Infection, Immunity, Inflammation and Physiological Medicine, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK Electronic address
    Physiotherapy 101:357-63. 2015
    ..To investigate differences, if any, in the delivery of respiratory treatments to mechanically ventilated children between non-respiratory on-call physiotherapists and specialist respiratory physiotherapists...
  38. pmc Impact of ethnicity and extreme prematurity on infant pulmonary function
    Ah Fong Hoo
    Portex Respiratory Unit, UCL Institute of Child Health, London, WC1N 1EH, UK Paediatric Respiratory Medicine Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK
    Pediatr Pulmonol 49:679-87. 2014
    ....
  39. ncbi request reprint Reference equations for pulmonary function tests in preschool children: a review
    Sanja Stanojevic
    Portex Respiratory Physiology Unit, UCL, Institute of Child Health, London, United Kingdom
    Pediatr Pulmonol 42:962-72. 2007
    ..This in turn would maximize the tremendous opportunities to detect early lung disease offered by the recent surge in developing suitable tests for preschool children...
  40. ncbi request reprint Clinical implications of pulmonary function testing in preschool children
    Janet Stocks
    Portex Unit Respiratory Physiology, UCL, Institute of Child Health, London, UK
    Paediatr Respir Rev 7:S26-9. 2006
    ....
  41. ncbi request reprint Gas mixing efficiency from birth to adulthood measured by multiple-breath washout
    Paul Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Respir Physiol Neurobiol 148:125-39. 2005
    ..Although methodological and analytical issues remain, the future clinical and research applications of MBW justify accelerated research in this field...
  42. doi request reprint Positive parental attitudes to participating in research involving newborn screened infants with CF
    Jane Chudleigh
    Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK
    J Cyst Fibros 12:234-40. 2013
    ..This study aimed to assess parental attitudes and the feasibility of recruiting and retaining both NBS infants with CF and healthy control infants to a longitudinal, observational study...
  43. ncbi request reprint Relative ability of full and partial forced expiratory maneuvers to identify diminished airway function in infants with cystic fibrosis
    Sarath C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Am J Respir Crit Care Med 166:1350-7. 2002
    ..In infants with CF, the raised volume technique identified diminished airway function more frequently than the tidal technique...
  44. ncbi request reprint The effect of parental smoking on lung function and development during infancy
    Janet Stocks
    Portex Anesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Respirology 8:266-85. 2003
    ....
  45. ncbi request reprint Lung function testing in acute neonatal respiratory disorders and chronic lung disease of infancy: a review series
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service NHS Trust, London, UK
    Pediatr Pulmonol 40:467-70. 2005
  46. ncbi request reprint Progressive decline in plethysmographic lung volumes in infants: physiology or technology?
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Am J Respir Crit Care Med 168:1003-9. 2003
    ..These findings emphasize the need to establish reference data for lung function tests in infants that are appropriate for the equipment and protocols in current use...
  47. doi request reprint Repeatability of physiotherapy chest wall vibrations applied to spontaneously breathing adults
    Harriet Shannon
    University College London, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Physiotherapy 95:36-42. 2009
    ..In order to understand their effects, it is essential to measure the forces applied and their repeatability over time. This study investigated the repeatability of vibrations within and between test occasions...
  48. doi request reprint Lung function testing in children: importance of race and ethnic-specific reference equations
    Janet Stocks
    Respiratory, Critical Care and Anaesthesia Section Portex Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Expert Rev Respir Med 8:527-31. 2014
    ....
  49. pmc Birth data accessibility via primary care health records to classify health status in a multi-ethnic population of children: an observational study
    Rachel Bonner
    Respiratory, Critical Care and Anaesthesia Section Portex Unit, UCL, Institute of Child Health, London, UK
    NPJ Prim Care Respir Med 25:14112. 2015
    ..Access to reliable birth data (birthweight (BW) and gestational age (GA)) is essential for the identification of individuals who are at subsequent health risk...
  50. ncbi request reprint Introduction and overview of preschool lung function testing
    Janet Stocks
    Portex Unit Respiratory Physiology, UCL, Institute of Child Health, London, UK
    Paediatr Respir Rev 7:S2-4. 2006
  51. doi request reprint Long-term impact of neonatal intensive care and surgery on somatosensory perception in children born extremely preterm
    Suellen M Walker
    Portex Unit, Pain Research and Respiratory Physiology, UCL Institute of Child Health, 6th Floor Cardiac Wing, 30 Guilford St, London WC1N 1EH, UK
    Pain 141:79-87. 2009
    ....
  52. pmc Effects of antenatal multiple micronutrient supplementation on lung function in mid-childhood: follow-up of a double-blind randomised controlled trial in Nepal
    Delan Devakumar
    Institute for Global Health, University College London, London, UK
    Eur Respir J 45:1566-75. 2015
    ..We conclude that, compared with routine iron and folic acid, multiple micronutrient supplementation during pregnancy has no effect on spirometric lung function in Nepalese children at 8.5 years of age...
  53. ncbi request reprint The influence of physiotherapy and suction on respiratory deadspace in ventilated children
    Eleanor Main
    Centre for Nursing and Allied Health Professionals Research and Physiotherapy Department, Institute of Child Health, 7th Floor, Old Building, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WCIN 3JH, UK
    Intensive Care Med 30:1152-9. 2004
    ....