Colin D Steer
Affiliation: University of Bristol
- Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphismsColin D Steer
Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK
Hum Mol Genet 21:1504-12. 2012..However, by 7 years, no associations were observed with the maternal genotype. This suggested that the children's FA levels were related only to their own metabolism with no apparent lasting influences of the in utero environment...
- Socio-demographic characteristics of UK families using pesticides and weed-killersColin D Steer
Community Based Medicine, University of Bristol, Bristol, UK
J Expo Sci Environ Epidemiol 16:251-63. 2006..They have also helped in identifying the important confounders for adjusting future analyses on the potential health consequences of pesticides and weed-killers...
- The variation in stool patterns from 1 to 42 months: a population-based observational studyC D Steer
Department of Community Based Medicine, University of Bristol, Bristol, UK
Arch Dis Child 94:231-3. 2009..To document the normal stool patterns of young children...
- Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is associated with spinal BMD in 9-year-old childrenColin D Steer
Department of Community Based Medicine, University of Bristol, Bristol, United Kingdom
J Bone Miner Res 24:117-24. 2009..To the extent that these findings reflect known influences of C677T MTHFR genotype on plasma homocysteine levels, our results suggest that the latter is an important regulator of spinal BMD in childhood...
- Traits contributing to the autistic spectrumColin D Steer
Social and Community Medicine, University of Bristol, Bristol, United Kingdom
PLoS ONE 5:e12633. 2010..It is increasingly recognised that traits associated with autism reflect a spectrum with no clear boundary between typical and atypical behaviour. Dimensional traits are needed to investigate the broader autism phenotype...
- FADS2 polymorphisms modify the effect of breastfeeding on child IQColin D Steer
Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
PLoS ONE 5:e11570. 2010..A study by Caspi et al has suggested that rs174575 within the FADS2 gene moderates this effect so that children homozygous in the minor allele (GG genotype) have similar IQs irrespective of feeding method...
- Dental associations with blood mercury in pregnant womenJean Golding
Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK
Community Dent Oral Epidemiol 44:216-22. 2016..This study therefore sets out to determine the extent to which dental amalgam (DA) may contribute to total blood mercury (TBHg) levels of pregnant women in the UK...
- Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of ageColin D Steer
School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom CDS and JG the Research Unit for Molecular Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany EL the Department of Pediatrics, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munchen, Germany BK and the NIH, National Institute on Alcohol Abuse and Alcoholism, Bethesda MD JRH
Am J Clin Nutr 98:1575-82. 2013..Brain tissue is selectively enriched with highly unsaturated fatty acids (FAs). Altering the maternal FA status in pregnancy may improve fetal neural development with lasting consequences for child development...
- Dependence of deodorant usage on ABCC11 genotype: scope for personalized genetics in personal hygieneSantiago Rodriguez
MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, and Bristol Genetic Epidemiology Laboratories BGEL, School of Social and Community Medicine, University of Bristol, Bristol, UK
J Invest Dermatol 133:1760-7. 2013..It also indicates potential cost saving to the nonodorous and scope for personalized genetics usage in personal hygiene choices, with consequent reduction of inappropriate chemical exposures for some...
- Insights into the programming of bone development from the Avon Longitudinal Study of Parents and Children (ALSPAC)Colin D Steer
Centre for Child and Adolescent Health and Academic Rheumatology, Southmead Hospital, University of Bristol, United Kingdom
Am J Clin Nutr 94:1861S-1864S. 2011..Together, these results confirm that there is a relation between bone development in childhood and several proxy measures for nutritional status in utero...
- Associations of size at birth and dual-energy X-ray absorptiometry measures of lean and fat mass at 9 to 10 y of ageImogen S Rogers
Department of Social Medicine, University of Bristol, Bristol, United Kingdom
Am J Clin Nutr 84:739-47. 2006..Birth weight has been positively associated with risk of overweight in later life. However, little information exists on how weight and length at birth are associated with subsequent lean and total body fat...
- Parental, prenatal, and neonatal associations with ball skills at age 8 using an exposome approachJean Golding
Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
J Child Neurol 29:1390-8. 2014..Future studies of this cohort will be used to determine whether the mechanism is manifest through differing parenting skills, or a biological mechanism reflecting epigenetic effects. ..
- Dietary predictors of maternal prenatal blood mercury levels in the ALSPAC birth cohort studyJean Golding
Centre for Child and Adolescent Health, University of Bristol, Bristol, United Kingdom
Environ Health Perspect 121:1214-8. 2013..It has been suggested that all possible sources of mercury should be avoided. However, although seafood is a known source of mercury, little is known about other dietary components that contribute to the overall levels of blood mercury...
- Influences on child fruit and vegetable intake: sociodemographic, parental and child factors in a longitudinal cohort studyLouise R Jones
Department of Social Medicine, University of Bristol, Bristol, UK
Public Health Nutr 13:1122-30. 2010..To examine the sociodemographic, parental and child factors that predict fruit and vegetable consumption in 7-year-old children...
- Habitual levels of physical activity influence bone mass in 11-year-old children from the United Kingdom: findings from a large population-based cohortJon H Tobias
University of Bristol, UK
J Bone Miner Res 22:101-9. 2007..Physical activity was positively related to both BMD and bone size in fully adjusted models. However, further exploration revealed that this effect on bone size was modified by fat mass...
- Prevalence and risk factors for reduced sound tolerance (hyperacusis) in childrenAmanda J Hall
a Children s Hearing Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
Int J Audiol 55:135-41. 2016..To estimate the prevalence of reduced sound tolerance (hyperacusis) in a UK population of 11-year-old children and examine the association of early life and auditory risk factors with report of hyperacusis...
- Preconception and prenatal environmental factors associated with communication impairments in 9 year old children using an exposome-wide approachColin D Steer
MRC integrative epidemiological unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
PLoS ONE 10:e0118701. 2015..Finally, there may be a mechanism via the maternal diet in pregnancy in particular the consumption of fatty or processed foods. This is the subject of ongoing investigation. ..
- Birth weight is positively related to bone size in adolescents but inversely related to cortical bone mineral density: findings from a large prospective cohort studyColin D Steer
Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, UK
Bone 65:77-82. 2014....