Charlotte J Stagg

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Widespread modulation of cerebral perfusion induced during and after transcranial direct current stimulation applied to the left dorsolateral prefrontal cortex
    Charlotte J Stagg
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain and Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Neurosci 33:11425-31. 2013
  2. pmc Neurochemical effects of theta burst stimulation as assessed by magnetic resonance spectroscopy
    C J Stagg
    Centre for Functional Resonance Imaging of the Brain, University of Oxford, Oxford, United Kingdom
    J Neurophysiol 101:2872-7. 2009
  3. pmc Cortical activation changes underlying stimulation-induced behavioural gains in chronic stroke
    Charlotte Jane Stagg
    Nuffield Department of Clinical Neurosciences, Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Brain 135:276-84. 2012
  4. pmc The role of GABA in human motor learning
    Charlotte J Stagg
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK
    Curr Biol 21:480-4. 2011
  5. doi Physiological basis of transcranial direct current stimulation
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Neuroscientist 17:37-53. 2011
  6. pmc Polarity and timing-dependent effects of transcranial direct current stimulation in explicit motor learning
    C J Stagg
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Neuropsychologia 49:800-4. 2011
  7. doi Imaging the effects of rTMS-induced cortical plasticity
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Restor Neurol Neurosci 28:425-36. 2010
  8. doi Autoantibodies to glutamic acid decarboxylase in patients with epilepsy are associated with low cortical GABA levels
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance of the Brain FMRIB, University of Oxford, Oxford, United Kingdom
    Epilepsia 51:1898-901. 2010
  9. doi Modulation of movement-associated cortical activation by transcranial direct current stimulation
    C J Stagg
    Centre for Functional MRI of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford UK
    Eur J Neurosci 30:1412-23. 2009
  10. doi Polarity-sensitive modulation of cortical neurotransmitters by transcranial stimulation
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom
    J Neurosci 29:5202-6. 2009

Detail Information

Publications30

  1. pmc Widespread modulation of cerebral perfusion induced during and after transcranial direct current stimulation applied to the left dorsolateral prefrontal cortex
    Charlotte J Stagg
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain and Nuffield Division of Anaesthetics, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Neurosci 33:11425-31. 2013
    ..2003). ..
  2. pmc Neurochemical effects of theta burst stimulation as assessed by magnetic resonance spectroscopy
    C J Stagg
    Centre for Functional Resonance Imaging of the Brain, University of Oxford, Oxford, United Kingdom
    J Neurophysiol 101:2872-7. 2009
    ..This direct evidence for increased GABAergic interneuronal activity is framed in terms of a new hypothesis regarding mechanisms underlying cTBS...
  3. pmc Cortical activation changes underlying stimulation-induced behavioural gains in chronic stroke
    Charlotte Jane Stagg
    Nuffield Department of Clinical Neurosciences, Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Brain 135:276-84. 2012
    ....
  4. pmc The role of GABA in human motor learning
    Charlotte J Stagg
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK
    Curr Biol 21:480-4. 2011
    ..This study therefore suggests that the responsiveness of the GABAergic system to modification may be relevant to short-term motor learning behavior and learning-related brain activity...
  5. doi Physiological basis of transcranial direct current stimulation
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Neuroscientist 17:37-53. 2011
    ..In addition, the theoretical framework for how tDCS affects motor learning is proposed...
  6. pmc Polarity and timing-dependent effects of transcranial direct current stimulation in explicit motor learning
    C J Stagg
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Neuropsychologia 49:800-4. 2011
    ..These results are consistent with the idea that anodal tDCS interacts with subsequent motor learning in a metaplastic manner and suggest that anodal stimulation modulates cortical excitability in a manner similar to motor learning...
  7. doi Imaging the effects of rTMS-induced cortical plasticity
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Restor Neurol Neurosci 28:425-36. 2010
    ..We discuss how variation in these effects in stroke patients may inform our understanding of how rTMS could improve function in these patients...
  8. doi Autoantibodies to glutamic acid decarboxylase in patients with epilepsy are associated with low cortical GABA levels
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance of the Brain FMRIB, University of Oxford, Oxford, United Kingdom
    Epilepsia 51:1898-901. 2010
    ....
  9. doi Modulation of movement-associated cortical activation by transcranial direct current stimulation
    C J Stagg
    Centre for Functional MRI of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford UK
    Eur J Neurosci 30:1412-23. 2009
    ..In addition, following sham stimulation compared with baseline, a between-session decrease in task-related activity was found. The effects of cathodal tDCS arose primarily from a reduction of this normal decrease...
  10. doi Polarity-sensitive modulation of cortical neurotransmitters by transcranial stimulation
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom
    J Neurosci 29:5202-6. 2009
    ....
  11. pmc Relationship between physiological measures of excitability and levels of glutamate and GABA in the human motor cortex
    C J Stagg
    Oxford Centre for Functional MRI of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    J Physiol 589:5845-55. 2011
    ....
  12. doi Brain imaging reveals that engagement of descending inhibitory pain pathways in healthy women in a low endogenous estradiol state varies with testosterone
    Katy Vincent
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division of Anaesthetics, University of Oxford, UK
    Pain 154:515-24. 2013
    ..Specifically, failure to engage descending inhibition at the level of the rostral ventromedial medulla may be responsible for the reduction in temperature required by COCP users with low circulating testosterone...
  13. pmc Diffusion imaging of whole, post-mortem human brains on a clinical MRI scanner
    Karla L Miller
    FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Neuroimage 57:167-81. 2011
    ..Despite these alterations, diffusion tractography of several major tracts is successfully demonstrated at both resolutions. We also report novel findings of cortical anisotropy and partial volume effects...
  14. pmc Perceptually relevant remapping of human somatotopy in 24 hours
    James Kolasinski
    Oxford Centre for fMRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
    elife 5:. 2016
    ....
  15. doi Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke
    Claire Allman
    Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Sci Transl Med 8:330re1. 2016
    ..The addition of ipsilesional anodal tDCS to a 9-day motor training program improved long-term clinical outcomes relative to sham treatment in patients after stroke. ..
  16. pmc Motor practice promotes increased activity in brain regions structurally disconnected after subcortical stroke
    Rosemary A Bosnell
    Nuffield Department of Clinical Neurosciences, Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK
    Neurorehabil Neural Repair 25:607-16. 2011
    ..Imaging studies in healthy individuals show that dynamic brain activation changes with practice. Defining patterns of functional brain plasticity associated with motor practice following stroke could guide rehabilitation...
  17. pmc Whole-brain magnetic resonance spectroscopic imaging measures are related to disability in ALS
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance of the Brain, University of Oxford, UK
    Neurology 80:610-5. 2013
    ....
  18. pmc Changes in functional connectivity and GABA levels with long-term motor learning
    Cassandra Sampaio-Baptista
    Oxford Centre for Functional MRI of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Neuroimage 106:15-20. 2015
    ..Our results further indicate that learning-related changes in resting-state network strength in part reflect GABAergic plastic processes...
  19. pmc Phosphene Perception Relates to Visual Cortex Glutamate Levels and Covaries with Atypical Visuospatial Awareness
    Devin B Terhune
    Department of Experimental Psychology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Cereb Cortex 25:4341-50. 2015
    ..These results suggest that phosphene perception is driven by interindividual variation in glutamatergic activity in primary visual cortex and relates to cortical processes underlying individual differences in visuospatial awareness. ..
  20. pmc Investigating the Stability of Fine-Grain Digit Somatotopy in Individual Human Participants
    James Kolasinski
    Oxford Centre for fMRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, United Kingdom, University College, Oxford OX1 4BH, United Kingdom, and
    J Neurosci 36:1113-27. 2016
    ..The simple task and 10 min scan required to derive these maps also raises the potential for this paradigm as a tool in the clinical setting...
  21. pmc Modulation of GABA and resting state functional connectivity by transcranial direct current stimulation
    Velicia Bachtiar
    Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
    elife 4:e08789. 2015
    ....
  22. pmc The Homeostatic Interaction Between Anodal Transcranial Direct Current Stimulation and Motor Learning in Humans is Related to GABAA Activity
    Ugwechi Amadi
    Oxford Centre for Functional MRI of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Brain Stimul 8:898-905. 2015
    ..Such timing-dependent effects have been ascribed to homeostatic plasticity, but the specific synaptic site of this interaction remains unknown...
  23. pmc A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology
    James Kolasinski
    Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford, Oxford, OX3 9DU, UK
    Brain 135:2938-51. 2012
    ....
  24. pmc Local GABA concentration is related to network-level resting functional connectivity
    Charlotte J Stagg
    Oxford Centre for Functional MRI of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
    elife 3:e01465. 2014
    ..DOI: http://dx.doi.org/10.7554/eLife.01465.001. ..
  25. pmc GABA predicts time perception
    Devin B Terhune
    Department of Experimental Psychology and Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, United Kingdom, and Douglas Mental Health University Institute and Department of Psychiatry, McGill University, Verdun, Quebec H4H 1R2, Canada
    J Neurosci 34:4364-70. 2014
    ..These results demonstrate anatomical, neurochemical, and task specificity and suggest that visual cortex GABA contributes to individual differences in time perception. ..
  26. pmc Relationships between functional and structural corticospinal tract integrity and walking post stroke
    Gowri Jayaram
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Clin Neurophysiol 123:2422-8. 2012
    ..However, such relationships have not been fully explored for the lower limb. We aimed to test whether variation in walking impairment was associated with variation in the structural or functional integrity of the CST...
  27. pmc Multi-modal characterization of rapid anterior hippocampal volume increase associated with aerobic exercise
    Adam G Thomas
    Section on Functional Imaging Methods, NIMH, NIH, DHHS, Bethesda, MD, USA FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom Electronic address
    Neuroimage 131:162-70. 2016
    ..It is also the first demonstration of hippocampal volume change over a period of only six weeks, suggesting that gross morphometric hippocampal plasticity occurs faster than previously thought. ..
  28. doi Altered neurochemical coupling in the occipital cortex in migraine with visual aura
    Holly Bridge
    Nuffield Department of Clinical Neuroscience, University of Oxford, UK Oxford Centre for Functional MRI of the Brain FMRIB, University of Oxford, UK
    Cephalalgia 35:1025-30. 2015
    ..Visual aura is present in about one-third of migraine patients and triggering by bright or flickering lights is frequently reported...
  29. doi Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype
    Sarosh R Irani
    1 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Brain 136:3151-62. 2013
    ..Immunotherapy is associated with excellent control of the frequently anti-epileptic drug refractory seizures, hastens time to recovery, and may prevent the subsequent development of cognitive impairment observed in this study. ..
  30. doi Dysmenorrhoea is associated with central changes in otherwise healthy women
    Katy Vincent
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division Anaesthetics, University of Oxford, UK
    Pain 152:1966-75. 2011
    ..These findings indicate the potential importance of early and adequate treatment of dysmenorrhoea...