Andrew J Smith

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. ncbi request reprint Microbial factors and gingival crevicular fluid aspartate aminotransferase levels. A cross-sectional study
    A J Smith
    Oral Sciences Unit, Glasgow Dental Hospital, UK
    J Clin Periodontol 25:334-9. 1998
  2. ncbi request reprint Prion diseases and dental treatment: principles and practice of patients with/suspected or at-risk of CJD: case reports
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ
    Br Dent J 195:319-21. 2003
  3. ncbi request reprint Prions and the oral cavity
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ, Scotland, UK
    J Dent Res 82:769-75. 2003
  4. ncbi request reprint A method for surveying instrument decontamination procedures in general dental practice
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Glasgow, UK
    Br Dent J 202:E20; discussion 472-3. 2007
  5. ncbi request reprint Staphylococcal species in the oral cavity from patients in a regional burns unit
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Level 9, 378 Sauchiehall Street, G2 3JZ, Glasgow, UK
    J Hosp Infect 55:184-9. 2003
  6. ncbi request reprint Staphylococcus aureus in the oral cavity: a three-year retrospective analysis of clinical laboratory data
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School
    Br Dent J 195:701-3; discussion 694. 2003
  7. ncbi request reprint Distribution of epidemic antibiotic-resistant pneumococcal clones in Scottish pneumococcal isolates analysed by multilocus sequence typing
    A J Smith
    Infection Research Group, Level 9, Glasgow Dental Hospital, 378 Sauchiehall Street, Glasgow G2 3JZ, UK
    Microbiology 152:361-5. 2006
  8. ncbi request reprint Residual protein levels on reprocessed dental instruments
    A Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ, Scotland, UK
    J Hosp Infect 61:237-41. 2005
  9. ncbi request reprint Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents
    A J Smith
    Infection Research Group, Glasgow Dental Hospital, Glasgow, Scotland, UK
    J Antimicrob Chemother 56:407-9. 2005
  10. ncbi request reprint Antimicrobial susceptibility of viridans group streptococcal blood isolates to eight antimicrobial agents
    Andrew Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow, UK
    Scand J Infect Dis 36:259-63. 2004

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Microbial factors and gingival crevicular fluid aspartate aminotransferase levels. A cross-sectional study
    A J Smith
    Oral Sciences Unit, Glasgow Dental Hospital, UK
    J Clin Periodontol 25:334-9. 1998
    ..gingivalis and A. actinomycetemcomitans. However, the GCF metabolites had a significant correlation with periodontally diseased sites in patients with chronic adult periodontitis and may help confirm clinical observations...
  2. ncbi request reprint Prion diseases and dental treatment: principles and practice of patients with/suspected or at-risk of CJD: case reports
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ
    Br Dent J 195:319-21. 2003
    ..This paper is based on real-life case scenarios and the advice given to dentists for the management of a group of patients with different manifestations of prion diseases...
  3. ncbi request reprint Prions and the oral cavity
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ, Scotland, UK
    J Dent Res 82:769-75. 2003
    ..This article reviews the existing knowledge base on the nature of prions, their distribution in oral tissues, and the implications for dental treatment...
  4. ncbi request reprint A method for surveying instrument decontamination procedures in general dental practice
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Glasgow, UK
    Br Dent J 202:E20; discussion 472-3. 2007
    ..This paper describes an objective method for assessing the decontamination procedures used for reprocessing dental instruments in primary dental care facilities...
  5. ncbi request reprint Staphylococcal species in the oral cavity from patients in a regional burns unit
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Level 9, 378 Sauchiehall Street, G2 3JZ, Glasgow, UK
    J Hosp Infect 55:184-9. 2003
    ..This study suggests that staphylococci are not infrequent colonizers of the oral cavity, and that this site may serve as a potential reservoir for transmission to other body sites...
  6. ncbi request reprint Staphylococcus aureus in the oral cavity: a three-year retrospective analysis of clinical laboratory data
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School
    Br Dent J 195:701-3; discussion 694. 2003
    ..A retrospective analysis of laboratory data to investigate the isolation of Staphylococcus aureus from the oral cavity and facial area in specimens submitted to a regional diagnostic oral microbiology laboratory...
  7. ncbi request reprint Distribution of epidemic antibiotic-resistant pneumococcal clones in Scottish pneumococcal isolates analysed by multilocus sequence typing
    A J Smith
    Infection Research Group, Level 9, Glasgow Dental Hospital, 378 Sauchiehall Street, Glasgow G2 3JZ, UK
    Microbiology 152:361-5. 2006
    ..The highest levels of penicillin resistance were detected in sequence type 320 (serotype 19F), which is not a PMEN clone. These data suggest that PMEN clones are not widely distributed in disease-causing isolates in Scotland...
  8. ncbi request reprint Residual protein levels on reprocessed dental instruments
    A Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ, Scotland, UK
    J Hosp Infect 61:237-41. 2005
    ..4 microg; range: 0.5-63.2 microg). These results demonstrate that the cleaning of some instruments reprocessed routinely in primary care is incomplete, and such instruments cannot be excluded as a potential source of cross-infection...
  9. ncbi request reprint Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents
    A J Smith
    Infection Research Group, Glasgow Dental Hospital, Glasgow, Scotland, UK
    J Antimicrob Chemother 56:407-9. 2005
    ..This study was conducted to assess the susceptibility of human clinical isolates of Actinomyces species to 12 antimicrobial agents...
  10. ncbi request reprint Antimicrobial susceptibility of viridans group streptococcal blood isolates to eight antimicrobial agents
    Andrew Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow, UK
    Scand J Infect Dis 36:259-63. 2004
    ..These findings are of concern in the light of spread of antibiotic resistance genes from S. oralis and S. mitis to the more invasive pneumococcus...
  11. doi request reprint Management of infection control in dental practice
    A Smith
    Infection Research Group, University of Glasgow Dental School, Faculty of Medicine, Glasgow, UK
    J Hosp Infect 71:353-8. 2009
    ..The training of staff in infection control and its documentation is poorly managed and consideration should be given to development of quality management systems for use in dental practice...
  12. doi request reprint Survey of the decontamination and maintenance of dental handpieces in general dental practice
    G W G Smith
    Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow
    Br Dent J 207:E7; discussion 160-1. 2009
    ..To determine how dental handpieces are decontaminated and maintained in general dental practice...
  13. doi request reprint Survey of instrument decontamination in dental surgeries located in Scottish prisons
    Andrew J Smith
    Infection Research Group, University of Glasgow Dental School, Glasgow Dental Hospital and School, Faculty of Medicine, Glasgow, Scotland
    Am J Infect Control 37:689-90. 2009
    ..The use of a central sterile supply service may be a more cost effective approach for the provision of compliant instrument reprocessing facilities in the sites surveyed...
  14. ncbi request reprint Management of needlestick injuries in general dental practice
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School
    Br Dent J 190:645-50. 2001
    ..Successful prophylaxis requires careful planning in advance. Whilst all practices should have a policy for sharps injuries, prevention of needlestick injuries remains the best policy...
  15. ncbi request reprint The ecology of Staphylococcus species in the oral cavity
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School
    J Med Microbiol 50:940-6. 2001
    ..Further work in this area may lead to benefits, such as improved decolonisation regimens for eradication of MRSA and acknowledgement of the mouth as a source of bacteraemic staphylococci...
  16. ncbi request reprint Use of chlorine dioxide to disinfect dental unit waterlines
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Glasgow, UK
    J Hosp Infect 49:285-8. 2001
    ..Units should be redesigned to discourage biofilm formation, and more research into practical methods of achieving potable water is required in the interim...
  17. ncbi request reprint Contaminated dental instruments
    A Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow, UK
    J Hosp Infect 51:233-5. 2002
    ..Improved cleaning methods and the feasibility of single use endodontic instruments require further investigation...
  18. ncbi request reprint Evaluation of the efficacy of Alpron disinfectant for dental unit water lines
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School
    Br Dent J 193:593-6; discussion 584. 2002
    ..To assess the efficacy of a disinfectant, Alpron, for controlling microbial contamination within dental unit water lines...
  19. ncbi request reprint A cross sectional study of water quality from dental unit water lines in dental practices in the West of Scotland
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Glasgow G2 3JZ
    Br Dent J 193:645-8; discussion 641. 2002
    ..To determine the microbiological quality of water from dental units in a general practice setting and current practice for disinfection of units...
  20. doi request reprint Design of dental surgeries in relation to instrument decontamination
    A J Smith
    Infection and Immunity Research Group, Glasgow Dental Hospital and School, Faculty of Medicine, University of Glasgow, Glasgow, UK
    J Hosp Infect 76:340-4. 2010
    ..This survey suggests that the historical location of dental surgeries in converted residential properties places many restrictions on appropriate design for healthcare premises...
  21. ncbi request reprint Presentation of a case of variant CJD in general dental practice
    A J Smith
    Infection Research Group, Glasgow Dental Hospital and School, Scotland
    Br Dent J 197:75-6. 2004
    ..This case report describes the initial presentation of variant CJD to a general dental practitioner. The case highlights the importance of prompt referral of patients presenting with a history of atypical facial symptoms...
  22. doi request reprint Evaluation of residual protein on unprocessed and decontaminated dental extraction forceps
    Gordon W G Smith
    Institute of Infection and Immunity, College of Medical, Veterinary and Life Sciences, Glasgow Dental Hospital and School, University of Glasgow, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK
    Biofouling 28:921-7. 2012
    ..The methods described, when used in conjunction with quantitative and surface analysis of instruments, can aid development of cleaning processes by identifying contaminants on used devices that have been removed following cleaning...
  23. ncbi request reprint Cross infection control measures and the treatment of patients at risk of Creutzfeldt Jakob disease in UK general dental practice
    J Bagg
    Trust Audit Office, Glasgow Dental Hospital School
    Br Dent J 191:87-90. 2001
    ..To determine the suitability of key infection control measures currently employed in UK dental practice for delivery of dental care to patients at risk of prion diseases...
  24. doi request reprint In vitro evaluation of cleaning efficacy of detergents recommended for use on dental instruments
    Gordon W G Smith
    Institute of Infection and Immunity, College of Medical Veterinary and Life Sciences, Glasgow Dental School, University of Glasgow, Glasgow, UK
    Am J Infect Control 40:e255-9. 2012
    ..An important factor is the choice of cleaning solution especially in the absence of any defined standards for detergent effectiveness...
  25. ncbi request reprint Superbugs and the dentist: an update
    Michael P Dawson
    Infection Research Group, Glasgow Dental Hospital and School, UK
    Dent Update 33:198-200, 202-4, 207-8. 2006
    ..This article explains the background to some commonly occurring antibiotic-resistant bacteria...
  26. ncbi request reprint Women with intellectual disability who have offended: characteristics and outcome
    W R Lindsay
    NHS Tayside, Dundee, Scotland, UK
    J Intellect Disabil Res 48:580-90. 2004
    ..Therefore, while we are building up a reasonable picture of this client group, there are almost no reports of female offenders with ID. This paper is a preliminary attempt to present information on a small cohort of female offenders...
  27. pmc Genomic diversity between strains of the same serotype and multilocus sequence type among pneumococcal clinical isolates
    Nuno A Silva
    Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    Infect Immun 74:3513-8. 2006
    ..Finally, we show that these clonal strains with the same serotype and ST behave differently in an animal model. Strains of the same ST and serotype therefore have important genetic and phenotypic differences...
  28. pmc Identification of a secreted cholesterol-dependent cytolysin (mitilysin) from Streptococcus mitis
    Johanna Jefferies
    Division of Infection and Immunity, Institute of Biomedical and Life Sciences, Glasgow Biomedical Research Centre, University of Glasgow, Glasgow G12 8TA, UK
    J Bacteriol 189:627-32. 2007
    ..As genetic exchange is known to occur between S. mitis and Streptococcus pneumoniae, this finding may have implications for the development of vaccines or therapies for pneumococcal disease that are based on pneumolysin...
  29. ncbi request reprint Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks
    Johanna M C Jefferies
    Institute of Biomedical and Life Sciences, Division of Infection and Immunity, University of Glasgow, Glasgow, United Kingdom
    J Infect Dis 196:936-44. 2007
    ..Serotype 1 and 8 pneumococci are known to be associated with outbreaks of invasive disease. The nonhemolytic pneumolysin allele is therefore associated with the dominant clones of outbreak-associated serotypes of S. pneumoniae...
  30. pmc Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin
    Lea Ann S Kirkham
    Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, Scotland
    J Clin Microbiol 44:151-9. 2006
    ..Pneumolysin is generally conserved throughout all serotypes of S. pneumoniae and is essential for full invasive disease; however, it appears that serotype 1 ST306 does not require hemolytically active pneumolysin to cause IPD...
  31. ncbi request reprint CJD and the dentist
    Andrew Smith
    Dent Update 30:462-3. 2003
  32. ncbi request reprint CJD and the dentist
    Andrew Smith
    Infection Research Group, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow
    Dent Update 30:180-6. 2003
    ..This article highlights the issues involved and discusses current guidelines for management of patients with human transmissible encephalopathies...
  33. ncbi request reprint Automated pneumococcal MLST using liquid-handling robotics and a capillary DNA sequencer
    Johanna Jefferies
    Scottish Meningococcus and Pneumococcus Reference Laboratory, North Glasgow University Hospital NHS Trust, Department of Microbiology, Stobhill Hospital, Balornock Rd, Glasgow, G21 3UW, UK
    Mol Biotechnol 24:303-8. 2003
    ..The SMPRL recently started performing MLST on strains of Streptococcus pneumoniae, and here we describe a fully automated method for MLST using a 96-well-format liquid-handling robot and a 96-capillary automated DNA sequencer...
  34. pmc Genetic analysis of diverse disease-causing pneumococci indicates high levels of diversity within serotypes and capsule switching
    Johanna M C Jefferies
    Institute of Biomedical and Life Sciences, Division of Infection and Immunity, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    J Clin Microbiol 42:5681-8. 2004
    ....
  35. ncbi request reprint Ethics and ethnography: an experiential account
    Dawn Goodwin
    Institute of Health Research, Lancaster University, U K
    Qual Health Res 13:567-77. 2003
    ..The authors argue that this process of shaping the data is a symbiotic one in which the researcher and the community being studied construct the data together...
  36. ncbi request reprint Leveraging the structure of the Semantic Web to enhance information retrieval for proteomics
    Andrew Smith
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA
    Bioinformatics 23:3073-9. 2007
    ..Moreover, we achieve this accuracy using only relatively simple and computationally efficient methods...
  37. ncbi request reprint Hearing impairment and socioeconomic factors: a population-based survey of an urban locality in southern Brazil
    Jorge Umberto Béria
    Graduate School of Public Health, Medical School, Lutheran University of Brazil, Canoas, Rio Grande do Sul, Brazil
    Rev Panam Salud Publica 21:381-7. 2007
    ..To provide the first population-based data on deafness and hearing impairment in Brazil...
  38. doi request reprint Hand hygiene practices of health care workers in long-term care facilities
    Andrew Smith
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    Am J Infect Control 36:492-4. 2008
    ..Overall hand hygiene adherence was 14.7%, with a mean handwashing time of 15.9 seconds. Adherence varied by activity performed and the presence or absence of a sink...
  39. ncbi request reprint A contemporary validation of the Reeder Stress Inventory
    Chris Metcalfe
    Department of Social Medicine, University of Bristol, UK
    Br J Health Psychol 8:83-94. 2003
    ..To examine the construct validity of the RSI in a contemporary cohort...
  40. pmc Experimental acute pancreatitis in PAP/HIP knock-out mice
    Meritxell Gironella
    INSERM, U 624, Marseille, France
    Gut 56:1091-7. 2007
    ..It was shown in vitro to be anti-apoptotic and anti-inflammatory. This study aims to look at whether PAP/HIP plays the same role in vivo...
  41. ncbi request reprint Oral focal mucinosis: report of 15 cases and review of the literature
    Michael J Aldred
    Dorevitch Pathology, Heidelberg, Victoria, Australia
    Pathology 35:393-6. 2003
    ..To describe 15 cases of oral focal mucinosis (OFM) and compare these to previously reported cases...
  42. ncbi request reprint The nurse practitioner's role in day case pre-operative assessment
    Lee Wadsworth
    Macclesfield District General Hospital
    Nurs Stand 16:41-4. 2002
    ..The authors found that the expanded role can work well in this setting and benefit patients...
  43. ncbi request reprint Temporal gene expression patterns in G93A/SOD1 mouse
    Ling Chun Chen
    The Forbes Norris ALS Research Center, California Pacific Medical Center Research Institute, San Francisco, CA 94115, USA
    Amyotroph Lateral Scler Other Motor Neuron Disord 5:164-71. 2004
    ..These changes were due to the presence of the mutant gene, and not simply to overexpression of a SOD1 gene. These findings are discussed in relation to possible roles of microglia function in the development of ALS...
  44. ncbi request reprint Job strain, effort--reward imbalance, and stress at work: competing or complementary models?
    Michael Calnan
    MRC HSRC, University of Bristol, UK
    Scand J Public Health 32:84-93. 2004
    ..The Demand Control Model (DCM) and the Effort Reward Imbalance Model (ERI) offer putative explanations of the relationship between stressful working conditions, job strain, and psychological and physical ill health...
  45. ncbi request reprint Surveys of plasma vitellogenin and intersex in male flounder (Platichthys flesus) as measures of endocrine disruption by estrogenic contamination in United Kingdom estuaries: temporal trends, 1996 to 2001
    Mark F Kirby
    Centre for Environment, Fisheries and Aquaculture Science Burnham Laboratory, Remembrance Avenue, Burnham on Crouch, Essex CM0 8HA, United Kingdom
    Environ Toxicol Chem 23:748-58. 2004
    ..The significance of the findings and possible mitigating influences are discussed in terms of the impacts on wild fish and the role of effluent treatment in reducing these...
  46. ncbi request reprint Computer security in academia-a potential roadblock to distributed annotation of the human genome
    Dov Greenbaum
    Department of Genetics, Yale University, New Haven, Connecticut 06520, USA
    Nat Biotechnol 22:771-2. 2004
  47. pmc Impediments to database interoperation: legal issues and security concerns
    Dov Greenbaum
    Nucleic Acids Res 33:D3-4. 2005
  48. ncbi request reprint Aortic pulse wave velocity and albuminuria in patients with type 2 diabetes
    Andrew Smith
    Unit for Metabolic Medicine, 5th Floor, Department of Diabetes and Endocrinology, Cardiovascular Division, GKT School of Medicine, King s College London, Guy s Hospital, St Thomas Street, London SE1 9RT, UK
    J Am Soc Nephrol 16:1069-75. 2005
    ..The association of Ao-PWV with reduced GFR suggests that even modest renal dysfunction may affect the viscoelastic properties of large arteries...
  49. pmc SARS among critical care nurses, Toronto
    Mark Loeb
    Department of Pathology and Molecualr Medicine, McMaster University, Hamilton, Ontario, Canada
    Emerg Infect Dis 10:251-5. 2004
    ..Risk was lower with consistent use of a N95 mask than with consistent use of a surgical mask. We conclude that activities related to intubation increase SARS risk and use of a mask (particularly a N95 mask) is protective...
  50. ncbi request reprint A transition probability model for amino acid substitutions from blocks
    Shalini Veerassamy
    Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada
    J Comput Biol 10:997-1010. 2003
    ..Our model is directly derived from, and thus compatible with, the BLOSUM matrices. The model has the additional advantage of being easily implemented...
  51. pmc Network security and data integrity in academia: an assessment and a proposal for large-scale archiving
    Andrew Smith
    Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
    Genome Biol 6:119. 2005
    ....
  52. pmc Importance of organosulfur utilization for survival of Pseudomonas putida in soil and rhizosphere
    Pascal Mirleau
    Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, England
    Appl Environ Microbiol 71:6571-7. 2005
    ....
  53. ncbi request reprint When the drug of choice is a drug of confusion: embalming fluid use in inner city Hartford, CT
    Merrill Singer
    Center for Community Health Research of the Hispanic Health Council, Hartford, CT 06106, USA
    J Ethn Subst Abuse 4:73-96. 2005
    ..The public health implications of this new wave of PCP use are assessed...
  54. ncbi request reprint Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis
    Chern Sing Goh
    Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Ave, New Haven, CT 06520, USA
    J Mol Biol 336:115-30. 2004
    ..This information may prove useful in optimizing high-throughput experimentation. Further information is available from http://mining.nesg.org/...
  55. pmc The legionnaires' outbreak in Barrow-in-Furness, summer 2002
    David Telford
    J Epidemiol Community Health 60:464-6. 2006
  56. ncbi request reprint Paruresis: a secret phobia
    Andrew Smith
    UK Paruresis Trust
    Nurs Times 102:44-5. 2006
  57. pmc Transmembrane protein oxygen content and compartmentalization of cells
    Rajkumar Sasidharan
    Molecular Biophysics and Biochemistry Department, Yale University, New Haven, Connecticut, United States of America
    PLoS ONE 3:e2726. 2008
    ....