John Simpson

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. ncbi The use of glyceryl trinitrate (GTN) in the treatment of chronic anal fissure in children
    John Simpson
    Department of Surgery, University Hospital, Nottingham, UK
    Med Sci Monit 9:PI123-6. 2003
  2. doi Perception and the origin of symptoms in diverticular disease
    John Simpson
    Department of General Surgery, University Hospital QMC, Nottingham, UK
    Dig Dis 30:75-9. 2012
  3. doi Post inflammatory damage to the enteric nervous system in diverticular disease and its relationship to symptoms
    J Simpson
    Department of General Surgery, Wolfson Digestive Diseases Centre, University Hospital, Nottingham, UK
    Neurogastroenterol Motil 21:847-e58. 2009
  4. pmc Swallowed dental bridge causing ileal perforation: a case report
    Farhan Rashid
    Department of Surgery, Derby City General Hospital, Uttoxeter Road, Derby, DE22 3NE, UK
    Cases J 1:392. 2008
  5. pmc Acute appendicitis--a benign disease?
    J Simpson
    Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Ann R Coll Surg Engl 90:313-6. 2008
  6. doi Rigler on the roof. Rigler's sign
    J Simpson
    Wolfson Digestive Diseases Centre, Division of Gastrointestinal Surgery, E West Block, Queens Medical Centre, Nottingham NG7 2UH, UK
    Gut 57:798, 836. 2008
  7. ncbi Pathogenesis of colonic diverticula
    J Simpson
    Departments of Surgery and Gastroenterology, University Hospital, Nottingham, UK
    Br J Surg 89:546-54. 2002
  8. ncbi Origin of symptoms in diverticular disease
    J Simpson
    Department of Surgery, University Hospital, Nottingham, UK
    Br J Surg 90:899-908. 2003
  9. ncbi Recent advances in diverticular disease
    John Simpson
    Department of Surgery, University Hospital, E Floor, West Block, Nottingham NG7 2UH, UK
    Curr Gastroenterol Rep 6:417-22. 2004
  10. ncbi Patterns of pain in diverticular disease and the influence of acute diverticulitis
    John Simpson
    Division of Surgery, University of Nottingham, Nottingham, UK
    Eur J Gastroenterol Hepatol 15:1005-10. 2003

Detail Information

Publications19

  1. ncbi The use of glyceryl trinitrate (GTN) in the treatment of chronic anal fissure in children
    John Simpson
    Department of Surgery, University Hospital, Nottingham, UK
    Med Sci Monit 9:PI123-6. 2003
    ..This double blind randomised pilot study assessed the efficacy and side effects of 0.1 and 0.05 per cent GTN ointment in treatment of chronic anal fissures in children...
  2. doi Perception and the origin of symptoms in diverticular disease
    John Simpson
    Department of General Surgery, University Hospital QMC, Nottingham, UK
    Dig Dis 30:75-9. 2012
    ..This article briefly outlines a model of GI perception and then highlights past and current theories that may explain the development of symptoms in patients with diverticulosis...
  3. doi Post inflammatory damage to the enteric nervous system in diverticular disease and its relationship to symptoms
    J Simpson
    Department of General Surgery, Wolfson Digestive Diseases Centre, University Hospital, Nottingham, UK
    Neurogastroenterol Motil 21:847-e58. 2009
    ..Patients with symptomatic diverticular disease exhibit increased neuropeptides in mucosal biopsies which may reflect resolved prior inflammation, as it parallels the changes seen in acute and chronic diverticulitis...
  4. pmc Swallowed dental bridge causing ileal perforation: a case report
    Farhan Rashid
    Department of Surgery, Derby City General Hospital, Uttoxeter Road, Derby, DE22 3NE, UK
    Cases J 1:392. 2008
    ..Although most swallowed foreign bodies pass through the gastrointestinal tract without problem, serious complications including intestinal perforation can occur...
  5. pmc Acute appendicitis--a benign disease?
    J Simpson
    Division of Gastrointestinal Surgery, Wolfson Digestive Disease Centre, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, UK
    Ann R Coll Surg Engl 90:313-6. 2008
    ..Most patients recover quickly but a minority can suffer postoperative complications. This case-note review was undertaken to assess the frequency of these complications...
  6. doi Rigler on the roof. Rigler's sign
    J Simpson
    Wolfson Digestive Diseases Centre, Division of Gastrointestinal Surgery, E West Block, Queens Medical Centre, Nottingham NG7 2UH, UK
    Gut 57:798, 836. 2008
  7. ncbi Pathogenesis of colonic diverticula
    J Simpson
    Departments of Surgery and Gastroenterology, University Hospital, Nottingham, UK
    Br J Surg 89:546-54. 2002
    ..This article reviews these aspects in relation to the pathogenesis of colonic diverticula...
  8. ncbi Origin of symptoms in diverticular disease
    J Simpson
    Department of Surgery, University Hospital, Nottingham, UK
    Br J Surg 90:899-908. 2003
    ..This article reviews the possible mechanisms that may be responsible for the symptoms of diverticular disease...
  9. ncbi Recent advances in diverticular disease
    John Simpson
    Department of Surgery, University Hospital, E Floor, West Block, Nottingham NG7 2UH, UK
    Curr Gastroenterol Rep 6:417-22. 2004
    ..Further research in these areas has the potential to provide targeted therapeutic strategies for people with colonic diverticula...
  10. ncbi Patterns of pain in diverticular disease and the influence of acute diverticulitis
    John Simpson
    Division of Surgery, University of Nottingham, Nottingham, UK
    Eur J Gastroenterol Hepatol 15:1005-10. 2003
    ..While the association of recurrent bouts of abdominal pain with colonic diverticulosis is well recognized, the cause of this pain is obscure since in most cases it occurs without obvious diverticulitis or other potential causes...
  11. doi A population-based study of perforated diverticular disease incidence and associated mortality
    David J Humes
    Wolfson Digestive Disease Centre, Nottingham University Hospital NHS Trust, and Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK
    Gastroenterology 136:1198-205. 2009
    ..We aimed to determine the incidence and mortality associated with diverticular perforation and the influence of comorbidity...
  12. doi Prolonged elevation of galanin and tachykinin expression in mucosal and myenteric enteric nerves in trinitrobenzene sulphonic acid colitis
    J Simpson
    Wolfson Digestive Diseases Centre, University of Nottingham, Nottingham, UK
    Neurogastroenterol Motil 20:392-406. 2008
    ..5 ratio was significantly increased in the mucosa throughout the study. Low-grade chronic inflammation after an acute initial insult causes a persistent increase in the expression of galanin in the mucosa and SP in muscle layer...
  13. pmc Acute appendicitis
    D J Humes
    Division of Gastrointestinal Surgery, Section of Surgery, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH
    BMJ 333:530-4. 2006
  14. doi The effects of morphine-neostigmine and secretin provocation on pancreaticobiliary morphology in healthy subjects: a randomized, double-blind crossover study using serial MRCP
    Abeed H Chowdhury
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    World J Surg 35:2102-9. 2011
    ..The aim of the present study was to use serial MRCP to characterize the effects of morphine-neostigmine and secretin provocation on serum pancreatic enzyme responses and pancreaticobiliary ductal morphology in healthy subjects...
  15. ncbi Diverticular abscess of the appendix: report of a case and review of the literature
    John Simpson
    Section of Surgery, University Hospital, Nottingham, United Kingdom
    Dis Colon Rectum 46:832-4. 2003
  16. ncbi Psychological and colonic factors in painful diverticulosis
    D J Humes
    Wolfson Digestive Diseases Centre, University of Nottingham, Nottingham, UK
    Br J Surg 95:195-8. 2008
    ..The importance of psychological factors in symptom expression in diverticulosis is unknown. This follow-up study assessed the relative importance of colonic and psychological factors in symptom expression...
  17. ncbi Surgical fires and alcohol-based skin preparations
    Rebecca Tooher
    Australian Safety and Efficacy Register of New Interventional Procedures Surgical, Royal Australasian College of Surgeons, Adelaide, South Australia
    ANZ J Surg 74:382-5. 2004
    ..Both cases were associated with use of electrocautery for haemostasis. The literature is reviewed and recommendations are made to reduce the risk of further similar occurrences...