Affiliation: University of Sheffield
- Synthesis and properties of amphiphilic networks 3: preparation and characterization of block conetworks of poly(butyl methacrylate-block-(2,3 propandiol-1-methacrylate-stat-ethandiol dimethacrylate))S Rimmer
Department of Chemistry The Polymer Centre and CTEB, The Polymer and Biomaterials Chemistry Laboratories, University of Sheffield, Sheffield, South Yorkshire S3 7HF, UK
Biomaterials 26:2219-30. 2005..Increasing the fractions of BMA, either in the random terpolymer or block networks, system had the effect of increasing both cell proliferation and viability (as measured by the Alamar Blue assay)...
- Cytocompatibility of poly(1,2 propandiol methacrylate) copolymer hydrogels and conetworks with or without alkyl amine functionalityStephen Rimmer
The Polymer and Biomaterials Chemistry Laboratories, Department of Chemistry, University of Sheffield, Sheffield, South Yorkshire S3 7HF, UK
Biomaterials 30:2468-78. 2009..There were no differences in the capacity of the materials to activate TNF-alpha production by macrophages however, there was a trend towards stimulation of lower levels of IL-6 and IL-1beta by the alkyl-aminated materials...
- Epithelialization of hydrogels achieved by amine functionalization and co-culture with stromal cellsStephen Rimmer
Polymer and Biomaterials Chemistry Laboratories, Chemistry Department, University of Sheffield, Sheffield, South Yorkshire S3 7HF, UK
Biomaterials 28:5319-31. 2007..We suggest this approach of amine functionalization combined with stromal/epithelial co-culture offers a promising new approach to achieving a secure corneal epithelium...
- Highly branched polymers with polymyxin end groups responsive to Pseudomonas aeruginosaProdip Sarker
Polymer and Biomaterials Chemistry Laboratories, Department of Chemistry, University of Sheffield, Sheffield, South Yorkshire, S3 7HF United Kingdom
Biomacromolecules 12:1-5. 2011..Cooling then progressed the polymer/bacteria aggregate through a bound LCST into an open polymer coil conformation that was not adhesive to P. aeruginosa ...
- Arginine functionalization of hydrogels for heparin binding--a supramolecular approach to developing a pro-angiogenic biomaterialLouisa Gilmore
Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK
Biotechnol Bioeng 110:296-317. 2013..The data suggests that heparin-binding hydrogels provide a promising approach to a pro-angiogenic biomaterial...
- Thermally reversible colloidal gels for three-dimensional chondrocyte cultureJames W Lapworth
Department of Chemistry, University of Sheffield, Sheffield S3 7HF, UK
J R Soc Interface 9:362-75. 2012..Chondrocytes remained viable in all of these materials for 24 days, increased in number and produced collagen type II and glycosaminoglycans...
- High molecular weight plant heteropolysaccharides stimulate fibroblasts but inhibit keratinocytesMunira Shahbuddin
Department of Materials Science and Engineering, Kroto Research Institute, University of Sheffield, Sheffield, United Kingdom
Carbohydr Res 375:90-9. 2013..This effect did not extend to supporting keratinocytes under conditions of media starvation but KGM did significantly help support adipose derived stem cells under media starvation conditions...
- Thermally responsive polymeric hydrogel brushes: synthesis, physical properties and use for the culture of chondrocytesJohn Collett
Department of Chemistry, University of Sheffield, Sheffield, South Yorkshire S3 7HF, UK
J R Soc Interface 4:117-26. 2007..The importance of the crosslink hydrogel component is illustrated by significant changes in cell attachment/cell viability as the crosslink density is changed...
- Binding bacteria to highly branched poly(N-isopropyl acrylamide) modified with vancomycin induces the coil-to-globule transitionJoanna Shepherd
School of Clinical Dentistry, University of Sheffield, Sheffield S10 2TA, UK
J Am Chem Soc 132:1736-7. 2010....
- Aqueous compatible polymers in bionanotechnologyS R Carter
Department of Chemistry Polymer Centre, University of Sheffield, Sheffield, South Yorkshire, S3 7HF, UK
IEE Proc Nanobiotechnol 152:169-76. 2005..g. the histidine-tagged protein fragment BRCA1. An overview of both of these areas of research is described outlining the diversity of these aqueous compatible polymers in molecular recognition processes at the nanoscale...
- Development of a calcium-chelating hydrogel for treatment of superficial burns and scaldsA J Bullock
Kroto Research Institute, North Campus, Broad Lane, Sheffield, S3 7HQ, UK
Regen Med 5:55-64. 2010....
- Functional graft poly(N-isopropyl acrylamide)s using reversible addition-fragmentation chain transfer (RAFT) polymerisationSteven R Carter
The Polymer and Biomaterials Chemistry Laboratories, Department of Chemistry Polymer Centre, Brook Hill, University of Sheffield, Sheffield, South Yorkshire, S3 7HF, UK
Macromol Biosci 7:975-86. 2007..The use of N-pyrrole dithioate groups was found to substantially increase the solubility of the branched polymers in conventional solvents...
- Examination of the effects of poly(N-vinylpyrrolidinone) hydrogels in direct and indirect contact with cellsLouise Elizabeth Smith
Department of Engineering Materials, The Kroto Institute, University of Sheffield, Sheffield, South Yorkshire S1 3JD, UK
Biomaterials 27:2806-12. 2006..Rather the phenomenon was observed to be the result of a dynamic interaction between the hydrogels and the cells...
- Amine functional hydrogels as selective substrates for corneal epithelializationEnas Hassan
Department of Materials Science and Engineering, The Kroto Research Institute, University of Sheffield, Broad Lane, Sheffield, S3 7HQ, UK
Acta Biomater 10:3029-37. 2014..The data support the development of hydrogels specific for epithelial formation. ..
- Culture of dermal fibroblasts and protein adsorption on block conetworks of poly(butyl methacrylate-block-(2,3 propandiol-1-methacrylate-stat-ethandiol dimethacrylate))Yun Sun
Chemistry Department, University of Sheffield, Sheffield, South Yorkshire S3 7HF, UK
Biomaterials 28:661-70. 2007..It is suggested that the difference in behaviour is derived from changes in the surface composition...
- Development of biodegradable electrospun scaffolds for dermal replacementKeith A Blackwood
Tissue Engineering Group, Department of Engineering Materials, Kroto Research Institute, University of Sheffield, North Campus, Broad Lane, Sheffield S3 7HQ, United Kingdom
Biomaterials 29:3091-104. 2008..In conclusion, the data supports the development of PLGA 85:15 and 75:25 electrospun polymer scaffolds as potential degradable biomaterials for dermal replacement...
- Proteomic analysis of Escherichia coli biofilms reveals the overexpression of the outer membrane protein OmpARowan Orme
University of Manchester, Faculty of Medicine and Human Health, Centre for Molecular Medicine, Department of Medical Genetics, Manchester, UK
Proteomics 6:4269-77. 2006..coli biofilms. These findings present OmpA as a potential target for biofilm inhibition and may contribute to the rational design of biofilm inhibiting hydrogel coatings for urinary catheters...
- Development of a three-dimensional organ culture model for corneal wound healing and corneal transplantationBojun Zhao
Biomedical Sciences, Department of Biological Sciences, Lancaster University, Lancaster, and Manchester Royal Eye Hospital, United Kingdom
Invest Ophthalmol Vis Sci 47:2840-6. 2006..To develop and evaluate a three-dimensional organ culture system of the cornea anterior chamber that could replicate the in vivo processes occurring during corneal wound healing and corneal transplantation...