M I Prince
Affiliation: University of Newcastle
- Glucocorticosteroids for primary biliary cirrhosisM Prince
Centre for Liver Research, 5th Floor, William Leech Building, Framlington Place, Newcastle, UK, NE3 IUD
Cochrane Database Syst Rev . 2005..Its progression may be influenced by immunosuppression. Glucocorticosteroids are potent immunosuppressive agents, but they are associated with significant adverse effects, including osteoporosis...
- Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosisM I Prince
Centre for Liver Research, University of Newcastle, Newcastle, UK
Gut 50:436-9. 2002..Rifampicin caused significant hepatitis in 7.3% (95% confidence interval 2.5-19.4%) of patients treated for cholestatic liver disease in our centre...
- Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis: results of a multicentre, randomized, placebo-controlled, cross-over trialM I Prince
Centre for Liver Research, Newcastle University Medical School, Framlington Place, Newcastle, Tyne and Wear, NE2 4LL, UK
Aliment Pharmacol Ther 17:137-43. 2003..We have previously reported, in an uncontrolled trial, an improvement in fatigue scores in patients with primary biliary cirrhosis given oral antioxidant supplementation. We now present data from a controlled trial...
- Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohortM I Prince
Newcastle University Medical School, Newcastle, UK
Gut 53:865-70. 2004..Many patients with primary biliary cirrhosis (PBC) are asymptomatic at the time of diagnosis. However, because most studies of asymptomatic PBC have been small and from tertiary centres, asymptomatic PBC remains poorly characterised...
- The geographical distribution of primary biliary cirrhosis in a well-defined cohortM I Prince
Centre for Liver Research, Newcastle Medical School, Framlington Place, Newcastle, England, UK
Hepatology 34:1083-8. 2001..PBC occurred to a density of 10.7 cases/km(2) in the highest risk areas. In conclusion, PBC is unevenly distributed in Northeast England. This may reflect one or more environmental risk factors in its etiology...