David Parker

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Dynamic systems approaches and levels of analysis in the nervous system
    David Parker
    Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK
    Front Physiol 4:15. 2013
  2. ncbi request reprint Variable properties in a single class of excitatory spinal synapse
    David Parker
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom
    J Neurosci 23:3154-63. 2003
  3. ncbi request reprint Activity-dependent feedforward inhibition modulates synaptic transmission in a spinal locomotor network
    David Parker
    Department of Zoology, University of Cambridge, Cambridge, CB2 3EJ, United Kingdom
    J Neurosci 23:11085-93. 2003
  4. ncbi request reprint Pharmacological approaches to functional recovery after spinal injury
    David Parker
    Department of Zoology, University of Cambridge, Downing Street Cambridge, CB2 3EJ, UK
    Curr Drug Targets CNS Neurol Disord 4:195-210. 2005
  5. pmc Complexities and uncertainties of neuronal network function
    David Parker
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Philos Trans R Soc Lond B Biol Sci 361:81-99. 2006
  6. ncbi request reprint Modulation of cellular and synaptic variability in the lamprey spinal cord
    David Parker
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    J Neurophysiol 97:44-56. 2007
  7. ncbi request reprint Developmental differences in neuromodulation and synaptic properties in the lamprey spinal cord
    D Parker
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Neuroscience 145:142-52. 2007
  8. pmc Neuronal network analyses: premises, promises and uncertainties
    David Parker
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, UK
    Philos Trans R Soc Lond B Biol Sci 365:2315-28. 2010
  9. doi request reprint Locomotor recovery after spinal cord lesions in the lamprey is associated with functional and ultrastructural changes below lesion sites
    Ria Mishaal Cooke
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    J Neurotrauma 26:597-612. 2009
  10. pmc Short-Term Synaptic Plasticity at Interneuronal Synapses Could Sculpt Rhythmic Motor Patterns
    Yan Jia
    Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK
    Front Neural Circuits 10:4. 2016

Collaborators

  • Erik Svensson
  • Ria Mishaal Cooke
  • Q Lan
  • Peter Verleyen
  • Joachim Schachtner
  • D B Sattelle
  • G W Zamponi
  • Sten Grillner
  • Michael Williams
  • A K Jones
  • Yan Jia
  • Stephen Richards
  • Jean B Peloquin
  • Sarah Bevan
  • Daniel Bopp
  • Martin Klingler
  • Riyue Bao
  • Alexandre Souvorov
  • Aaron J Mackey
  • Victor Solovyev
  • Steven E Scherer
  • Peter Atkinson
  • Jeffrey G Scott
  • Garth Brown
  • Jeffrey Garnes
  • Erica Sodergren
  • Nadine Wittkopp
  • Selina Vattahil
  • Giddy Landan
  • Justin T Reese
  • Jeff Lord
  • Robin E Denell
  • Yoshiaki Tanaka
  • Douglas W Drury
  • Picheng Zhao
  • Marek Jindra
  • Robin Denell
  • Jeremy A Lynch
  • Cassondra M Gordon
  • Jireh Santibanez
  • Susan J Brown
  • Dean Chavez
  • Alica Hawes
  • Donna Villasana
  • Vincent Laudet
  • Cris Oppert
  • Boran Altincicek
  • Markus Friedrich
  • Peter Kosarev
  • Rita Wright
  • Ngoc Nguyen
  • Andrea Kowis
  • Doreen Werner
  • Nicola Berns
  • Maurijn van der Zee
  • Christian J Buhay
  • Jay Evans
  • Giuseppe Cazzamali
  • Reinhard Predel
  • Yoonseong Park
  • Siegfried Roth
  • Mizuko Osanai
  • Joel Savard
  • Michael Schoppmeier
  • Victor Sapojnikov
  • Jochen Trauner
  • Kerstin P Clerk-Blankenburg
  • Burkhard Morgenstern
  • Paul Kitts
  • Susan Brown
  • Lan Zhang
  • Shannon Dugan-Rocha
  • Sherry C Miller
  • Radhika Dixit
  • Jim Beidler
  • Tony Attaway
  • Konstantin Vinokurov
  • Hugh M Robertson
  • Elena Elpidina
  • Frank Hauser
  • Christine G Elsik
  • Kim Pruitt
  • Stephanie Bell
  • Michel Vervoort
  • Jennifer Hume
  • Nico Posnien
  • Margaret Morgan
  • Gerald Fowler
  • Florian Raible
  • Eran Elhaik

Detail Information

Publications15

  1. pmc Dynamic systems approaches and levels of analysis in the nervous system
    David Parker
    Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK
    Front Physiol 4:15. 2013
    ....
  2. ncbi request reprint Variable properties in a single class of excitatory spinal synapse
    David Parker
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom
    J Neurosci 23:3154-63. 2003
    ..The selection of interneurons with different synaptic properties could provide an intrinsic mechanism for modifying excitatory network interactions and the locomotor network output...
  3. ncbi request reprint Activity-dependent feedforward inhibition modulates synaptic transmission in a spinal locomotor network
    David Parker
    Department of Zoology, University of Cambridge, Cambridge, CB2 3EJ, United Kingdom
    J Neurosci 23:11085-93. 2003
    ..This could help to terminate ipsilateral motor neuron spiking during network activity...
  4. ncbi request reprint Pharmacological approaches to functional recovery after spinal injury
    David Parker
    Department of Zoology, University of Cambridge, Downing Street Cambridge, CB2 3EJ, UK
    Curr Drug Targets CNS Neurol Disord 4:195-210. 2005
    ..The properties of endogenous transmitter systems in spinal locomotor networks before and after spinal lesions need to be understood, and pharmacological tools that target specific functional aspects need to be developed...
  5. pmc Complexities and uncertainties of neuronal network function
    David Parker
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Philos Trans R Soc Lond B Biol Sci 361:81-99. 2006
    ....
  6. ncbi request reprint Modulation of cellular and synaptic variability in the lamprey spinal cord
    David Parker
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    J Neurophysiol 97:44-56. 2007
    ..These results suggest that cellular and synaptic variability can be targeted for modulation, making it an additional source of spinal cord plasticity...
  7. ncbi request reprint Developmental differences in neuromodulation and synaptic properties in the lamprey spinal cord
    D Parker
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Neuroscience 145:142-52. 2007
    ..These results suggest that opposite developmental changes in excitatory and inhibitory synaptic transmission and their modulation are associated with developmental differences in spinal cord neuromodulation...
  8. pmc Neuronal network analyses: premises, promises and uncertainties
    David Parker
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, UK
    Philos Trans R Soc Lond B Biol Sci 365:2315-28. 2010
    ..This introduction discusses the criteria that need to be satisfied for network understanding, and how they relate to traditional and novel approaches being applied to addressing network function...
  9. doi request reprint Locomotor recovery after spinal cord lesions in the lamprey is associated with functional and ultrastructural changes below lesion sites
    Ria Mishaal Cooke
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    J Neurotrauma 26:597-612. 2009
    ..The lamprey offers a tractable model system in which to investigate how interactions between altered locomotor networks and regenerated axons are organized to promote locomotor recovery...
  10. pmc Short-Term Synaptic Plasticity at Interneuronal Synapses Could Sculpt Rhythmic Motor Patterns
    Yan Jia
    Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK
    Front Neural Circuits 10:4. 2016
    ..As this plasticity could influence the patterning of the network output it should be considered as a potential functional component of spinal cord networks. ..
  11. ncbi request reprint Metaplastic facilitation and ultrastructural changes in synaptic properties are associated with long-term modulation of the lamprey locomotor network
    Sarah Bevan
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, United Kingdom
    J Neurosci 24:9458-68. 2004
    ..Substance P thus has long-term effects on synaptic organization and function. The relevance of these effects to the long-term locomotor network modulation is discussed...
  12. doi request reprint Manipulations of spinal cord excitability evoke developmentally-dependent compensatory changes in the lamprey spinal cord
    Ria Mishaal Cooke
    Department of Zoology, University of Cambridge, Cambridge, UK
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 198:25-41. 2012
    ..The spinal cord can thus monitor and adapt cellular and synaptic properties to tonic changes in excitability levels. This should be considered in analyses of spinal cord plasticity and injury...
  13. ncbi request reprint Synaptically evoked membrane potential oscillations induced by substance P in lamprey motor neurons
    Erik Svensson
    Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, S 171 77 Stockholm, Sweden
    J Neurophysiol 87:113-21. 2002
    ..Substance P thus has a distributed excitatory effect in the spinal cord. While it can activate premotor networks, this activation alone is not able to evoke a coordinated behaviorally relevant motor output...
  14. ncbi request reprint Functional analysis of Ca3.2 T-type calcium channel mutations linked to childhood absence epilepsy
    Jean B Peloquin
    Department of Physiology and Biophysics, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta
    Epilepsia 47:655-8. 2006
    ..Childhood absence epilepsy (CAE) is an idiopathic form of seizure disorder that is believed to have a genetic basis...
  15. doi request reprint The genome of the model beetle and pest Tribolium castaneum
    Stephen Richards
    Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA
    Nature 452:949-55. 2008
    ..Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control...