David Paling

Summary

Affiliation: University College London
Country: UK

Publications

  1. doi request reprint Sodium accumulation is associated with disability and a progressive course in multiple sclerosis
    David Paling
    NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    Brain 136:2305-17. 2013
  2. doi request reprint Reduced R2' in multiple sclerosis normal appearing white matter and lesions may reflect decreased myelin and iron content
    David Paling
    NMR Research Unit, Department of Neuroinflammation, UCL Institute of Neurology, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 83:785-92. 2012
  3. doi request reprint Energy failure in multiple sclerosis and its investigation using MR techniques
    David Paling
    NMR Research Unit, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    J Neurol 258:2113-27. 2011
  4. pmc Cerebral arterial bolus arrival time is prolonged in multiple sclerosis and associated with disability
    David Paling
    Department of Neuroinflammation, UCL Institute of Neurology, Queen Square MS Centre, London, UK
    J Cereb Blood Flow Metab 34:34-42. 2014
  5. doi request reprint Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial
    Rhian Raftopoulos
    National Hospital for Neurology and Neurosurgery, London, UK University College London Institute of Neurology, London, UK Queen Square Multiple Sclerosis Centre, London, UK
    Lancet Neurol 15:259-69. 2016

Collaborators

Detail Information

Publications5

  1. doi request reprint Sodium accumulation is associated with disability and a progressive course in multiple sclerosis
    David Paling
    NMR Research Unit, Department of Neuroinflammation, Queen Square Multiple Sclerosis Centre, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    Brain 136:2305-17. 2013
    ..Increased total sodium concentration is likely to reflect neuroaxonal pathophysiology leading to clinical progression and increased disability...
  2. doi request reprint Reduced R2' in multiple sclerosis normal appearing white matter and lesions may reflect decreased myelin and iron content
    David Paling
    NMR Research Unit, Department of Neuroinflammation, UCL Institute of Neurology, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 83:785-92. 2012
    ..R(2)' may detect features of multiple sclerosis (MS) not evident with conventional MRI...
  3. doi request reprint Energy failure in multiple sclerosis and its investigation using MR techniques
    David Paling
    NMR Research Unit, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK
    J Neurol 258:2113-27. 2011
    ....
  4. pmc Cerebral arterial bolus arrival time is prolonged in multiple sclerosis and associated with disability
    David Paling
    Department of Neuroinflammation, UCL Institute of Neurology, Queen Square MS Centre, London, UK
    J Cereb Blood Flow Metab 34:34-42. 2014
    ..Bolus arrival time was longer in patients with greater disability independent of atrophy and T2 lesion load, suggesting alterations in cerebral arterial hemodynamics may be a marker of clinically relevant pathology. ..
  5. doi request reprint Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial
    Rhian Raftopoulos
    National Hospital for Neurology and Neurosurgery, London, UK University College London Institute of Neurology, London, UK Queen Square Multiple Sclerosis Centre, London, UK
    Lancet Neurol 15:259-69. 2016
    ..Inhibition of voltage-gated sodium channels is neuroprotective in preclinical models. In this study we aimed to establish whether sodium-channel inhibition with phenytoin is neuroprotective in patient with acute optic neuritis...