Affiliation: University of York
- Helicobacter pylori and cancer among adults in UgandaRobert Newton
Epidemiology and Genetics Unit, Dept, of Health Sciences, First Floor, Seebohm Rowntree Building, University of York, Heslington, York, YO10 5DD, UK
Infect Agent Cancer 1:5. 2006..The prevalence of H. pylori reported here is broadly in accord with results from other developing countries, although the determinants of infection and its' role in the aetiology of gastric cancer in Uganda remain unclear...
- Parasite infection is associated with Kaposi's sarcoma associated herpesvirus (KSHV) in Ugandan womenKatie Wakeham
Co infections Studies Programme, Medical Research Council Uganda Virus Research Institute Uganda Research Unit on AIDS, PO Box 49, Entebbe, Uganda
Infect Agent Cancer 6:15. 2011....
- Impact of infection with human immunodeficiency virus-1 (HIV) on the risk of cancer among children in Malawi - preliminary findingsNora Mutalima
Epidemiology and Genetics Unit, Department of Health Sciences, Seebohm Rowntree Building, Area 3, University of York, York YO10 5DD, UK
Infect Agent Cancer 5:5. 2010..This study reports findings for children recruited between 2005 and 2008...
- A case-control study of cancer of the uterine cervix in UgandaRobert Newton
Epidemiology and Genetics Unit, Department of Health Sciences, University of York, York, UK
Eur J Cancer Prev 16:555-8. 2007..4; P=0.004], perhaps reflecting an earlier age of infection with human papillomavirus, the main causal agent. These results are in line with those reported from studies in other countries...
- Hodgkin's lymphoma and infection: findings from a UK case-control studyR Newton
Department of Health Sciences, Epidemiology and Genetics Unit, University of York, Area 3 Seebohm Rowntree Building, Heslington, York YO10 5DD, UK
Br J Cancer 97:1310-4. 2007..02). This excess was not due to a specific infection(s) and may reflect underlying immune abnormality. Alternatively, infection may cause B-cell proliferation from which a malignant clone may evolve...
- BK virus and cancer in UgandaRobert Newton
Epidemiology and Genetics Unit, Department of Health Sciences, University of York, Heslington, York, UK
Eur J Cancer Prev 15:285-9. 2006..The number of cases of each cancer was too small to exclude the possibility of these findings arising by chance. No other cancer site or type was significantly associated with low, or with high anti-BK virus antibody titres...
- A prospective study of Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus in adults with human immunodeficiency virus-1R Newton
Epidemiology and Genetics Unit, Department of Health Sciences, Area 3, Seebohm Rowntree Building, Heslington, York YO10 5DD, UK
Br J Cancer 94:1504-9. 2006..Antibody titre to EBV does not appear to be strongly associated with subsequent risk of Kaposi's sarcoma or non-Hodgkin's lymphoma in HIV infected people...
- Antibody levels against BK virus and prostate, kidney and bladder cancers in the EPIC-Oxford cohortR Newton
Epidemiology and Genetics Unit, Department of Health Sciences, Heslington, York, UK
Br J Cancer 93:1305-6. 2005....
- Mother-to-child transmission of human herpesvirus-8 in South AfricaMartin Dedicoat
Liverpool School of Tropical Medicine, Liverpool, and Cancer Research UK Epidemiology Unit, Oxford, United Kingdom
J Infect Dis 190:1068-75. 2004..1-6.2). The presence of HHV-8 DNA in maternal saliva was unrelated to latent antibodies in children. Saliva could be a route of transmission of HHV-8 from person to person, although other routes cannot be ruled out...
- Risk factors for Kaposi's sarcoma: a case-control study of HIV-seronegative people in UgandaJohn Ziegler
Uganda Cancer Institute and Makerere University Medical School, Kampala, Uganda
Int J Cancer 103:233-40. 2003..7; p < 0.001). The risk of Kaposi's sarcoma is clearly linked to antibody status for KSHV, but it would seem that in Uganda other factors are also important in the development of the tumour...
- Antibodies against malaria and Epstein-Barr virus in childhood Burkitt lymphoma: a case-control study in UgandaLucy M Carpenter
Department of Public Health, University of Oxford, Old Road Campus, Oxford OX3 7LF, United Kingdom
Int J Cancer 122:1319-23. 2008..0; p = 0.003). Our findings suggest that EBV and malaria may act synergistically in the pathogenesis of childhood Burkitt lymphoma. Malaria prevention measures may also prevent this childhood cancer...
- The sero-epidemiology of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in adults with cancer in UgandaRobert Newton
Cancer Research UK, Epidemiology Unit, Radcliffe Infirmary, Oxford, United Kingdom
Int J Cancer 103:226-32. 2003..03). In conclusion, in this population in Uganda, where KSHV is relatively common, the prevalence of anti-KSHV antibodies increased with age but showed little association with nearly 50 other factors studied...
- A prospective pilot study of antibodies against human papillomaviruses and cutaneous squamous cell carcinoma nested in the Oxford component of the European Prospective Investigation into Cancer and NutritionDelphine Casabonne
Cancer Epidemiology Unit, Richard Doll Building, University of Oxford, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7LF, United Kingdom
Int J Cancer 121:1862-8. 2007..Further and larger prospective studies are needed to clarify the role of HPV in the aetiology of cutaneous SCC...
- Influence of HLA alleles on shedding of Kaposi sarcoma-associated herpesvirus in saliva in an African populationKhaled R Alkharsah
Institute of Virology, Hannover Medical School, Hannover, 30625, Germany
J Infect Dis 195:809-16. 2007....
- IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthaseMatthew C Catley
Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College Faculty of Medicine, SW3 6LY, London, UK
FEBS Lett 547:75-9. 2003..However, other pathways are primarily responsible for PGE2 release induced by PMA...
- Cancer in rural KwaZulu-NatalMartin Dedicoat
S Afr Med J 93:846-7. 2003
- A case-control study of vanishing twin as a risk factor for cerebral palsyRobert Newton
Epidemiology Unit, Gibson Building, Radcliffe Infirmary, Oxford, OX2 6HE, UK
Twin Res 6:83-4. 2003..8-3.0; p = 0.3). On the basis of results presented here, the vanishing twin syndrome is unlikely to account for a high proportion of cases of cerebral palsy, but there is insufficient statistical power to draw firm conclusions...
- Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA bindingMatthew C Catley
Department of Thoracic Medicine, National Heart and Lung Institute, Imperial College, Dovehouse Street, London SW3 6LY, United Kingdom
J Biol Chem 279:18457-66. 2004....
- High frequency and diversity of cutaneous appendageal tumors in organ transplant recipientsCatherine A Harwood
Department of Academic Dermatology and Cancer Research, London, UK
J Am Acad Dermatol 48:401-8. 2003..Recipients of organ transplant who are immunosuppressed are at greatly increased risk of nonmelanoma skin cancers compared with the general population, but their risk of appendageal tumors is unknown...
- Associations between Burkitt lymphoma among children in Malawi and infection with HIV, EBV and malaria: results from a case-control studyNora Mutalima
Department of Public Health, University of Oxford, Oxford, United Kingdom
PLoS ONE 3:e2505. 2008..Burkitt lymphoma, a childhood cancer common in parts of sub-Saharan Africa, has been associated with Epstein Barr Virus (EBV) and malaria, but its association with human immunodeficiency virus (HIV) is not clear...
- Nuclear factor-kappaB does not mediate the inhibitory effects of dexamethasone on granulocyte-macrophage colony-stimulating factor expressionMartin W Bergmann
Department of Thoracic Medicine, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK
Immunology 111:430-4. 2004..These data therefore confirm a critical role for both NF-kappaB and CLE0 sites in GM-CSF promoter activation and indicate that NF-kappaB may not mediate glucocorticoid-dependent repression of GM-CSF in these cells...
- Human transcriptome subtraction by using short sequence tags to search for tumor viruses in conjunctival carcinomaHuichen Feng
Molecular Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA
J Virol 81:11332-40. 2007..It provides, for the first time, quantitative evidence against some classes of viral etiology when no viral transcripts are found, thereby reducing the uncertainty involved in new pathogen discovery...