A M Mortimer
Affiliation: University of Hull
- Primary care use of antipsychotic drugs: an audit and intervention studyAnn M Mortimer
Foundation Chair in Psychiatry Head of Department, The Department of Psychiatry, The University of Hull, Cottingham Road, Hull, HU6 7RX, UK
Ann Gen Psychiatry 4:18. 2005..Concerns regarding the use of antipsychotic medication in secondary care suggested an examination of primary care prescribing...
- Update on the management of symptoms in schizophrenia: focus on amisulprideAnn M Mortimer
Department of Psychiatry, Hertford Building, The University of Hull, Cottingham Road, Hull HU6 7RX, United Kingdom
Neuropsychiatr Dis Treat 5:267-77. 2009....
- Can antipsychotics improve social cognition in patients with schizophrenia?Katarzyna Kucharska-Pietura
NAViGO, Grimsby, UK
CNS Drugs 27:335-43. 2013..Other non-pharmacological treatments focusing on training patients in the social cognitive areas may hold more promise...
- Conventional antipsychotic prescription in unipolar depression, II: withdrawing conventional antipsychotics in unipolar, nonpsychotic patientsAnn M Mortimer
Department of Psychiatry, the University of Hull School of Medicine, Willerby, United Kingdom
J Clin Psychiatry 64:668-72; quiz 738-9. 2003..Concerns regarding these patients' polypharmacy, duration of treatment, and risk of long-term or undetected side effects led to their being contacted with a view to the discontinuation of conventional antipsychotic treatment...
- Antipsychotic treatment in schizophrenia: atypical options and NICE guidanceAnn M Mortimer
The Department of Psychiatry, University of Hull, East Riding Campus Willerby, Hull HU10 6NS, UK
Eur Psychiatry 18:209-19. 2003..There is a welcome emphasis on drug treatment as part of an integrated package of care negotiated with patients and their carers...
- Clozapine for treatment-resistant schizophrenia: National Institute of Clinical Excellence (NICE) guidance in the real worldAnn M Mortimer
Department of Psychiatry, University of Hull, Hertford Building, Cottingham Road, Hull, East Yorkshire, HU6 7RX, U K
Clin Schizophr Relat Psychoses 4:49-55. 2010..Levels of ongoing clinical problems were compared between treatment-resistant patients on clozapine, treatment-resistant patients not on clozapine, and non-treatment-resistant patients...
- How do we choose between atypical antipsychotics? The advantages of amisulprideAnn M Mortimer
Department of Psychiatry, The University of Hull, East Riding Campus, Beverley Road, Willerby, Hull HU10 6NS, UK
Int J Neuropsychopharmacol 7:S21-5. 2004..In two clinical trials, the AMIRIS and SOLIANOL studies, amisulpride demonstrated clear advantages over some other atypical antipsychotics with respect to negative symptoms, depressive symptoms and weight gain...
- A double-blind, randomized comparative trial of amisulpride versus olanzapine for 6 months in the treatment of schizophreniaAnn Mortimer
University of Hull, Hull, UK
Int Clin Psychopharmacol 19:63-9. 2004..1% and 3.9 kg) than in the amisulpride group (20.6% and 1.6 kg). The efficacy of amisulpride is not inferior to that of olanzapine in the treatment of acute schizophrenia. The side-effect profile of the two drugs differed...
- Treatment with amisulpride and olanzapine improve neuropsychological function in schizophreniaAnn M Mortimer
University of Hull, Hull, UK
Hum Psychopharmacol 22:445-54. 2007..Although antipsychotic drugs control acute psychotic manifestations of schizophrenia, improving cognitive symptoms is also important for long-term prognosis...
- Relationship between estrogen and schizophreniaA M Mortimer
The University of Hull, Department of Psychiatry, Hertford Building, Cottingham Road, Hull HU6 7RX, UK
Expert Rev Neurother 7:45-55. 2007....
- Symptom rating scales and outcome in schizophreniaAnn M Mortimer
Department of Psychiatry, University of Hull
Br J Psychiatry Suppl 50:s7-14. 2007..Symptom rating scales are now well established in schizophrenia research but their scores are not the same as outcome...
- Somatic treatment of psychotic depression: review and recommendations for practiceJ A Wheeler Vega
Department of Psychiatry, University of Hull, England
J Clin Psychopharmacol 20:504-19. 2000..These recommendations aim to minimize the number of treatments used and unwanted effects experienced...
- Cognitive function and social abilities in patients with schizophrenia: relationship with atypical antipsychoticsPhilip J Tyson
School of Natural and Social Sciences, University of Gloucestershire, Cheltenham, UK
Psychiatry Clin Neurosci 60:473-9. 2006..These findings accord with the notion that serotonergic mechanisms are important determinants of both the cognitive and the social effects of the atypical antipsychotics...
- Are the cognitive effects of atypical antipsychotics influenced by their affinity to 5HT-2A receptors?Philip J Tyson
School of Health and Social Sciences, University of Gloucestershire, Francis Close Hall Campus, Cheltenham, Gloucestershire, United Kingdom
Int J Neurosci 114:593-611. 2004..In contrast, the low-5HT-2A affinity group showed improvements on these measures in addition to others. The 5HT-2A affinity of the atypical antipsychotics is an important determinant of their cognitive effects...
- Quality of life in schizophrenia on conventional versus atypical antipsychotic medication: a comparative cross-sectional studyAnn M Mortimer
Department of Psychiatry, University of Hull, UK
Int J Soc Psychiatry 53:99-107. 2007..Atypical antipsychotic drugs, with superior tolerability and possibly superior efficacy, were expected to give schizophrenia patients better quality of life (QOL) than conventional treatment. Research findings are equivocal...
- Conventional antipsychotic prescription in unipolar depression, I: an audit and recommendations for practiceJason A Wheeler Vega
Department of Psychology, New School for Social Research, New York, NY, USA
J Clin Psychiatry 64:568-74. 2003..Despite narrow indications for conventional antipsychotics in depression, recent reports confirm a suspicion that they are widely prescribed in nonpsychotic depressive conditions...
- Early development and unstable genes in schizophrenia: preliminary resultsAgnes Ayton
Department of Psychiatry, University of Hull, East Riding Campus, Coniston House, Willerby, East Yorkshire HU10 6NS, UK
Eur Psychiatry 17:332-8. 2002..Trinucleotide repeats have been associated with schizophrenia, but the evidence, based on cross-sectional clinical information, is equivocal...
- Stability of set-shifting and planning abilities in patients with schizophreniaPhilip J Tyson
School of Health and Social Sciences, University of Gloucestershire, Francis Close Hall Campus, Swindon Road, Cheltenham, Gloucestershire, GL50 4AZ, UK
Psychiatry Res 129:229-39. 2004..This study accords with the presence of executive processing deficits in schizophrenia that are stable across time...
- Novel antipsychotics in schizophreniaAnn M Mortimer
Department of Psychiatry, University of Hull, UK
Expert Opin Investig Drugs 13:315-29. 2004..Progress in drug treatment for schizophrenia is confronted by several areas of difficulty which, barring serendipity, must be resolved before real advances can be anticipated...
- Intellectual differences between schizophrenic patients and normal controls across the adult lifespanTejinder K Kondel
Department of Clinical and Health Psychology, University College London, London, UK
J Clin Exp Neuropsychol 25:1045-56. 2003..We propose that the lower NART IQ in older patients reflects a lower 'starting point' and that this may be related to lower educational opportunities in older patients...