Kei Miyamoto

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development
    Kei Miyamoto
    Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK
    Science 341:1002-5. 2013
  2. pmc Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins
    Kei Miyamoto
    The Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN, UK
    Cell Mol Life Sci 70:3289-302. 2013
  3. pmc Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming
    Jerome Jullien
    Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, Cambridge CB2 1QN, UK Department of Zoology, University of Cambridge, Cambridge CB2 1QN, UK
    Mol Cell 55:524-36. 2014
  4. pmc Histone H3 lysine 9 trimethylation is required for suppressing the expression of an embryonically activated retrotransposon in Xenopus laevis
    Sarah Herberg
    Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
    Sci Rep 5:14236. 2015
  5. pmc Epigenetic factors influencing resistance to nuclear reprogramming
    Vincent Pasque
    Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
    Trends Genet 27:516-25. 2011
  6. pmc The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos
    Kei Miyamoto
    Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 10:e0142946. 2015
  7. pmc Sperm and spermatids contain different proteins and bind distinct egg factors
    Marta Teperek
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Int J Mol Sci 15:16719-40. 2014
  8. pmc Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process?
    Jerome Jullien
    Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
    Nat Rev Mol Cell Biol 12:453-9. 2011
  9. pmc Reprogramming and development in nuclear transfer embryos and in interspecific systems
    Patrick Narbonne
    The Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom
    Curr Opin Genet Dev 22:450-8. 2012

Collaborators

Detail Information

Publications10

  1. pmc Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development
    Kei Miyamoto
    Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK
    Science 341:1002-5. 2013
    ..We identify Wave1 as a maternal reprogramming factor that also has a necessary role in gene activation in development. ..
  2. pmc Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins
    Kei Miyamoto
    The Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN, UK
    Cell Mol Life Sci 70:3289-302. 2013
    ..This review summarizes roles of nuclear actin and actin-binding proteins in transcriptional regulation. We also discuss possible functions of nuclear actin during reprogramming in the context of transcription and chromatin remodeling...
  3. pmc Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming
    Jerome Jullien
    Wellcome Trust Cancer Research UK Gurdon Institute, Tennis Court Road, Cambridge CB2 1QN, UK Department of Zoology, University of Cambridge, Cambridge CB2 1QN, UK
    Mol Cell 55:524-36. 2014
    ..Thus, our study reveals the rapid, abundant, and stepwise loading of oocyte-specific factors onto somatic chromatin as important determinants for successful reprogramming. ..
  4. pmc Histone H3 lysine 9 trimethylation is required for suppressing the expression of an embryonically activated retrotransposon in Xenopus laevis
    Sarah Herberg
    Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
    Sci Rep 5:14236. 2015
    ..Thus, our study shows that H3K9me3 is important for silencing the developmentally regulated retrotransposon in Xenopus laevis. ..
  5. pmc Epigenetic factors influencing resistance to nuclear reprogramming
    Vincent Pasque
    Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
    Trends Genet 27:516-25. 2011
    ..We see this as a step towards understanding the mechanisms by which nuclear reprogramming takes place...
  6. pmc The Expression of TALEN before Fertilization Provides a Rapid Knock-Out Phenotype in Xenopus laevis Founder Embryos
    Kei Miyamoto
    Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 10:e0142946. 2015
    ..The experimental scheme presented is potentially applicable to other organisms such as mammals and fish to resolve common issues of mosaicism in founders. ..
  7. pmc Sperm and spermatids contain different proteins and bind distinct egg factors
    Marta Teperek
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Int J Mol Sci 15:16719-40. 2014
    ....
  8. pmc Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process?
    Jerome Jullien
    Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
    Nat Rev Mol Cell Biol 12:453-9. 2011
    ..These events occur in an ordered manner and on a defined timescale, indicating that reprogramming by nuclear transfer and by cell fusion rely on deterministic processes...
  9. pmc Reprogramming and development in nuclear transfer embryos and in interspecific systems
    Patrick Narbonne
    The Wellcome Trust Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom
    Curr Opin Genet Dev 22:450-8. 2012
    ..Interspecific incompatibilities hinder full exploitation of cross-species reprogramming systems, yet recent findings suggest that these may not constitute insurmountable obstacles...