Denisse L Leyton

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. doi request reprint The unusual extended signal peptide region is not required for secretion and function of an Escherichia coli autotransporter
    Denisse L Leyton
    School of Immunity and Infection, University of Birmingham, Birmingham, UK
    FEMS Microbiol Lett 311:133-9. 2010
  2. pmc Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins
    Denisse L Leyton
    School of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom
    J Biol Chem 286:42283-91. 2011
  3. pmc A generalised module for the selective extracellular accumulation of recombinant proteins
    Yanina R Sevastsyanovich
    School of Immunity and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    Microb Cell Fact 11:69. 2012
  4. pmc The essential β-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis
    Amanda E Rossiter
    School of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom
    J Bacteriol 193:4250-3. 2011
  5. doi request reprint Transcription of the plasmid-encoded toxin gene from enteroaggregative Escherichia coli is regulated by a novel co-activation mechanism involving CRP and Fis
    Amanda E Rossiter
    School of Immunity and Infection School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK
    Mol Microbiol 81:179-91. 2011
  6. pmc Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults
    Calman A MacLennan
    Medical Research Council Centre for Immune Regulation and Clinical Immunology Service, Institute of Biomedical Research, School of Immunity and Infection, University of Birmingham, Birmingham, UK
    Science 328:508-12. 2010
  7. doi request reprint From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis
    Denisse L Leyton
    School of Immunity and Infection, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK denisse leyton monash edu
    Nat Rev Microbiol 10:213-25. 2012
  8. pmc Structure and function of BamE within the outer membrane and the β-barrel assembly machine
    Timothy J Knowles
    School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    EMBO Rep 12:123-8. 2011

Detail Information

Publications8

  1. doi request reprint The unusual extended signal peptide region is not required for secretion and function of an Escherichia coli autotransporter
    Denisse L Leyton
    School of Immunity and Infection, University of Birmingham, Birmingham, UK
    FEMS Microbiol Lett 311:133-9. 2010
    ..In this study, we demonstrate that the ESPR is not essential for the secretion or the function of Pet...
  2. pmc Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins
    Denisse L Leyton
    School of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom
    J Biol Chem 286:42283-91. 2011
    ..These latter data strongly support the hairpin mode of autotransporter biogenesis...
  3. pmc A generalised module for the selective extracellular accumulation of recombinant proteins
    Yanina R Sevastsyanovich
    School of Immunity and Infection, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    Microb Cell Fact 11:69. 2012
    ..It is widely believed that laboratory strains of Escherichia coli, including those used for industrial production of proteins, do not secrete proteins to the extracellular milieu...
  4. pmc The essential β-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis
    Amanda E Rossiter
    School of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom
    J Bacteriol 193:4250-3. 2011
    ..In this report, we detail the role of the other BAM components (BamB-E). We identify the importance of BamD in autotransporter biogenesis and show that BamB, BamC, and BamE are not required...
  5. doi request reprint Transcription of the plasmid-encoded toxin gene from enteroaggregative Escherichia coli is regulated by a novel co-activation mechanism involving CRP and Fis
    Amanda E Rossiter
    School of Immunity and Infection School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK
    Mol Microbiol 81:179-91. 2011
    ..This study complements previous findings that establish Fis as a key virulence regulator in EAEC 042...
  6. pmc Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults
    Calman A MacLennan
    Medical Research Council Centre for Immune Regulation and Clinical Immunology Service, Institute of Biomedical Research, School of Immunity and Infection, University of Birmingham, Birmingham, UK
    Science 328:508-12. 2010
    ....
  7. doi request reprint From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis
    Denisse L Leyton
    School of Immunity and Infection, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK denisse leyton monash edu
    Nat Rev Microbiol 10:213-25. 2012
    ..Here, we discuss how these studies have led to an improved understanding of the mechanisms responsible for autotransporter biogenesis...
  8. pmc Structure and function of BamE within the outer membrane and the β-barrel assembly machine
    Timothy J Knowles
    School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    EMBO Rep 12:123-8. 2011
    ....