Raphael Levy

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. ncbi request reprint Rational and combinatorial design of peptide capping ligands for gold nanoparticles
    Raphael Levy
    Center for Nanoscale Science, University of Liverpool, Liverpool L69 7ZB, UK
    J Am Chem Soc 126:10076-84. 2004
  2. ncbi request reprint A generic approach to monofunctionalized protein-like gold nanoparticles based on immobilized metal ion affinity chromatography
    Raphael Levy
    Centre for Nanoscale Science, School of Biological Sciences, Department of Chemistry, University of Liverpool, Liverpool, L69 7ZB, UK
    Chembiochem 7:592-4. 2006
  3. ncbi request reprint Peptide-capped gold nanoparticles: towards artificial proteins
    Raphael Levy
    School of Biological Sciences, Centre for Nanoscale Science, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK
    Chembiochem 7:1141-5. 2006
  4. ncbi request reprint The peptide route to multifunctional gold nanoparticles
    Zhenxin Wang
    Centre for Nanoscale Science, Department of Chemistry, The University of Liverpool, Liverpool, UK
    Bioconjug Chem 16:497-500. 2005
  5. doi request reprint Computational and Experimental Investigation of the Structure of Peptide Monolayers on Gold Nanoparticles
    Elena Colangelo
    Institute of Integrative Biology, University of Liverpool, Crown Street, L69 7ZB Liverpool, U K
    Langmuir . 2016
  6. pmc TAT and HA2 facilitate cellular uptake of gold nanoparticles but do not lead to cytosolic localisation
    Yann Cesbron
    Department of Chemistry, University of Liverpool, Liverpool, United Kingdom Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom CNRS, UMR 6290, Institute of Genetics and Development of Rennes, Rennes, France Université de Rennes 1, Universite Europeenne de Bretagne, Structure fédérative de recherche Biosit, Faculte de Medecine, Rennes, France
    PLoS ONE 10:e0121683. 2015
  7. doi request reprint Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?
    Arthur Taylor
    Institute of Translational Medicine, University of Liverpool, Crown Street, L69 3BX, Liverpool, United Kingdom
    Chem Soc Rev 41:2707-17. 2012
  8. doi request reprint Supramolecular domains in mixed peptide self-assembled monolayers on gold nanoparticles
    Laurence Duchesne
    School of Biological Sciences and Liverpool Institute of Nanoscale Science, Engineering and Technology, University of Liverpool, Biosciences Building, Crown Street, Liverpool L697ZB, UK
    Chembiochem 9:2127-34. 2008
  9. doi request reprint Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo
    Joan Comenge
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom
    ACS Nano 10:7106-16. 2016
  10. doi request reprint Characterizing Self-Assembled Monolayers on Gold Nanoparticles
    Elena Colangelo
    Institute of Integrative Biology, University of Liverpool, Crown Street, L69 7ZB Liverpool, United Kingdom
    Bioconjug Chem 28:11-22. 2017

Collaborators

  • Violaine See
  • Laurence Duchesne
  • Dave J Adams
  • Lara K Bogart
  • David A Middleton
  • Ian A Prior
  • Daniel J Rigden
  • Irshad Hussain
  • Elena Colangelo
  • Martin Volk
  • Arthur Taylor
  • Yann Cesbron
  • Joan Comenge
  • Patricia Murray
  • Mathias Brust
  • David G Fernig
  • Qiubo Chen
  • David Paramelle
  • Changye Sun
  • Michael Barrow
  • Adam M Davidson
  • Paul Free
  • Zeljka Krpetić
  • Christopher P Shaw
  • Zhenxin Wang
  • Oihane Fragueiro
  • Marie Held
  • Bettina Wilm
  • Jack Sharkey
  • Brian Kevin Park
  • David Mason
  • Yong Li
  • Neal C Burton
  • Michael B Sullivan
  • Marco Marcello
  • Jeffrey J Chalmers
  • Lee R Moore
  • Christopher M Collins
  • Daniel J Nieves
  • Matthew J Rosseinsky
  • Steve R Williams
  • Pranab Mandal
  • Umbreen Shaheen
  • David L Cooper
  • James P Birchall
  • Chris P Shaw
  • Katie M Wilson

Detail Information

Publications16

  1. ncbi request reprint Rational and combinatorial design of peptide capping ligands for gold nanoparticles
    Raphael Levy
    Center for Nanoscale Science, University of Liverpool, Liverpool L69 7ZB, UK
    J Am Chem Soc 126:10076-84. 2004
    ..A simple strategy for the introduction of recognition groups is proposed and demonstrated with biotin and Strep-tag II...
  2. ncbi request reprint A generic approach to monofunctionalized protein-like gold nanoparticles based on immobilized metal ion affinity chromatography
    Raphael Levy
    Centre for Nanoscale Science, School of Biological Sciences, Department of Chemistry, University of Liverpool, Liverpool, L69 7ZB, UK
    Chembiochem 7:592-4. 2006
  3. ncbi request reprint Peptide-capped gold nanoparticles: towards artificial proteins
    Raphael Levy
    School of Biological Sciences, Centre for Nanoscale Science, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK
    Chembiochem 7:1141-5. 2006
    ..Recent applications as artificial enzymes and artificial enzyme substrates are presented. The limitations and long-term potential of peptide-capped nanoparticles as artificial proteins are discussed...
  4. ncbi request reprint The peptide route to multifunctional gold nanoparticles
    Zhenxin Wang
    Centre for Nanoscale Science, Department of Chemistry, The University of Liverpool, Liverpool, UK
    Bioconjug Chem 16:497-500. 2005
    ..Stabilization and biofunctionalization has been achieved in a single preparative step starting with citrate-stabilized gold hydrosols and a derivatization cocktail of peptide-capping ligands, which carry the functionalities of choice...
  5. doi request reprint Computational and Experimental Investigation of the Structure of Peptide Monolayers on Gold Nanoparticles
    Elena Colangelo
    Institute of Integrative Biology, University of Liverpool, Crown Street, L69 7ZB Liverpool, U K
    Langmuir . 2016
    ..The model developed here provides a predictive tool that may assist in the design of further bionanomaterials...
  6. pmc TAT and HA2 facilitate cellular uptake of gold nanoparticles but do not lead to cytosolic localisation
    Yann Cesbron
    Department of Chemistry, University of Liverpool, Liverpool, United Kingdom Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom CNRS, UMR 6290, Institute of Genetics and Development of Rennes, Rennes, France Université de Rennes 1, Universite Europeenne de Bretagne, Structure fédérative de recherche Biosit, Faculte de Medecine, Rennes, France
    PLoS ONE 10:e0121683. 2015
    ..While their uptake increased when the TAT and/or HA2 viral peptides were present on their surface, we did not observe a significant cytosolic delivery of the gold nanoparticles. ..
  7. doi request reprint Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?
    Arthur Taylor
    Institute of Translational Medicine, University of Liverpool, Crown Street, L69 3BX, Liverpool, United Kingdom
    Chem Soc Rev 41:2707-17. 2012
    ..We also examine the findings obtained in pre-clinical studies that expose potential misinterpretation that can occur when using inorganic nanoparticles for in vivo imaging...
  8. doi request reprint Supramolecular domains in mixed peptide self-assembled monolayers on gold nanoparticles
    Laurence Duchesne
    School of Biological Sciences and Liverpool Institute of Nanoscale Science, Engineering and Technology, University of Liverpool, Biosciences Building, Crown Street, Liverpool L697ZB, UK
    Chembiochem 9:2127-34. 2008
    ..Comparison of the experimental results with a probabilistic model demonstrates that the peptides are not randomly distributed at the surface of the nanoparticle, but rather self-organize into supramolecular domains...
  9. doi request reprint Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo
    Joan Comenge
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom
    ACS Nano 10:7106-16. 2016
    ..Importantly, the silica-coated nanorods did not affect the viability or differentiation potential of the transplanted mesenchymal stem cells. ..
  10. doi request reprint Characterizing Self-Assembled Monolayers on Gold Nanoparticles
    Elena Colangelo
    Institute of Integrative Biology, University of Liverpool, Crown Street, L69 7ZB Liverpool, United Kingdom
    Bioconjug Chem 28:11-22. 2017
    ..The methods and strategies discussed focus on the characterization of self-assembled monolayers at the gold nanoparticle surface, but most of them could also be applied to other types of nanoparticles...
  11. doi request reprint High-resolution sizing of monolayer-protected gold clusters by differential centrifugal sedimentation
    Zeljka Krpetić
    Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom
    ACS Nano 7:8881-90. 2013
    ..Unlike TEM, DCS is highly sensitive to small changes in the thickness of the organic ligand shell and can be applied to monitor shell thickness variations of as little as 0.1 nm on particles of a given core size. ..
  12. pmc Stripy nanoparticles revisited
    Yann Cesbron
    Structural and Chemical Biology, Institute of Integrative Biology, University of Liverpool Biosciences Bldg, Crown Street, L69 7ZB, UK CNRS, UMR 6290, Institut Génétique et Développement de Rennes, F 35043 Rennes, France, Universite de Rennes 1, Universite Europeenne de Bretagne, Structure fédérative de recherche Biosit, Faculte de Medecine, F 35043 Rennes, France
    Small 8:3714-9. 2012
    ..Using simple geometrical arguments, fast-Fourier transform and experimental investigations, we conclude that the observed stripes are an imaging artifact...
  13. doi request reprint Amyloid-derived peptide forms self-assembled monolayers on gold nanoparticle with a curvature-dependent β-sheet structure
    Christopher P Shaw
    Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom
    ACS Nano 6:1416-26. 2012
    ..Coupling is detected for CFGAILSS-capped gold nanoparticles, however, consistent with an intermolecular (13)C-(13)C distance of 5.0 ± 0.3 Å, in agreement with intermolecular hydrogen bonding in a parallel β-sheet structure...
  14. doi request reprint Cathepsin L digestion of nanobioconjugates upon endocytosis
    Violaine See
    Centre for Cell Imaging, University of Liverpool, UK
    ACS Nano 3:2461-8. 2009
    ..Preservation of the bioconjugates can be achieved by a combination of cathepsin inhibition and endosome disruption...
  15. pmc Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix
    Changye Sun
    Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK
    Open Biol 6:. 2016
    ..Moreover, cells regulate the spatial distribution of different protein-binding sites in glycosaminoglycans independently of each other, implying that the extracellular matrix has long-range structure. ..
  16. doi request reprint Tailoring the surface charge of dextran-based polymer coated SPIONs for modulated stem cell uptake and MRI contrast
    Michael Barrow
    Department of Chemistry, University of Liverpool, Liverpool, UK
    Biomater Sci 3:608-16. 2015
    ..Cell tracking velocimetry was shown to be a more accurate method for predicting MRI contrast of stem cells compared to measuring iron oxide uptake through conventional bulk iron quantification. ..