Paul Leeson

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi request reprint Breast Milk Consumption in Preterm Neonates and Cardiac Shape in Adulthood
    Adam J Lewandowski
    Oxford Cardiovascular Clinical Research Facility, and Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
    Pediatrics 138:. 2016
  2. ncbi request reprint Pediatric prevention of atherosclerosis: targeting early variation in vascular biology
    Paul Leeson
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Pediatrics 119:1204-6. 2007
  3. ncbi request reprint Atrial pathology in cardiac amyloidosis: evidence from ECG and cardiovascular magnetic resonance
    C Paul Leeson
    Department of Cardiology, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK
    Eur Heart J 27:1670. 2006
  4. doi request reprint MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Circulation 119:2507-15. 2009
  5. doi request reprint Right ventricular systolic dysfunction in young adults born preterm
    Adam J Lewandowski
    Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX39DU, UK
    Circulation 128:713-20. 2013
  6. doi request reprint Impaired endothelial responses in apparently healthy young people associated with subclinical variation in blood pressure and cardiovascular phenotype
    Merzaka Lazdam
    Department of Cardiovascular Medicine, University of Oxford, Oxford, UK
    Am J Hypertens 25:46-53. 2012
  7. doi request reprint Antenatal glucocorticoid exposure and long-term alterations in aortic function and glucose metabolism
    Brenda A Kelly
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
    Pediatrics 129:e1282-90. 2012
  8. doi request reprint Concentric left ventricular remodeling and aortic stiffness: a comparison of obesity and hypertension
    Oliver J Rider
    Department of Cardiovascular Medicine, University of Oxford, UK
    Int J Cardiol 167:2989-94. 2013
  9. doi request reprint Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Eur Heart J 30:1142-50. 2009
  10. pmc GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function
    Charalambos Antoniades
    Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
    J Am Coll Cardiol 52:158-65. 2008

Collaborators

Detail Information

Publications49

  1. doi request reprint Breast Milk Consumption in Preterm Neonates and Cardiac Shape in Adulthood
    Adam J Lewandowski
    Oxford Cardiovascular Clinical Research Facility, and Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
    Pediatrics 138:. 2016
    ..We hypothesized that being fed human breast milk during early postnatal life is beneficial to long-term cardiac structure and function in preterm-born individuals compared with infant formulas...
  2. ncbi request reprint Pediatric prevention of atherosclerosis: targeting early variation in vascular biology
    Paul Leeson
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Pediatrics 119:1204-6. 2007
  3. ncbi request reprint Atrial pathology in cardiac amyloidosis: evidence from ECG and cardiovascular magnetic resonance
    C Paul Leeson
    Department of Cardiology, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK
    Eur Heart J 27:1670. 2006
  4. doi request reprint MTHFR 677 C>T Polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Circulation 119:2507-15. 2009
    ..We sought to distinguish the effects of plasma versus vascular tissue 5-MTHF and homocysteine on vascular redox and endothelial nitric oxide bioavailability in human vessels...
  5. doi request reprint Right ventricular systolic dysfunction in young adults born preterm
    Adam J Lewandowski
    Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX39DU, UK
    Circulation 128:713-20. 2013
    ..Animal studies suggest that cardiomyocyte changes are evident in both ventricles after preterm birth; therefore, we investigated whether these young adults also have differences in their right ventricular structure and function...
  6. doi request reprint Impaired endothelial responses in apparently healthy young people associated with subclinical variation in blood pressure and cardiovascular phenotype
    Merzaka Lazdam
    Department of Cardiovascular Medicine, University of Oxford, Oxford, UK
    Am J Hypertens 25:46-53. 2012
    ..We identified subjects with persistently reduced, or declining, endothelial function during adolescence and early adulthood, without apparent cardiovascular risk, and investigated the clinical relevance of this finding...
  7. doi request reprint Antenatal glucocorticoid exposure and long-term alterations in aortic function and glucose metabolism
    Brenda A Kelly
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
    Pediatrics 129:e1282-90. 2012
    ..Animal studies have demonstrated long-term effects of in utero glucocortcoid exposure on vascular development and glucose metabolism. We hypothesized that there would be a similar impact in humans...
  8. doi request reprint Concentric left ventricular remodeling and aortic stiffness: a comparison of obesity and hypertension
    Oliver J Rider
    Department of Cardiovascular Medicine, University of Oxford, UK
    Int J Cardiol 167:2989-94. 2013
    ..However, obesity is characterized predominantly by increased abdominal aortic stiffness and with eccentric left ventricular hypertrophy...
  9. doi request reprint Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Eur Heart J 30:1142-50. 2009
    ..However, the mechanisms relating ADMA with vascular function have been evaluated in vitro and in animal models, but its effect in human vasculature is unclear...
  10. pmc GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function
    Charalambos Antoniades
    Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom
    J Am Coll Cardiol 52:158-65. 2008
    ....
  11. pmc Global and regional left ventricular myocardial deformation measures by magnetic resonance feature tracking in healthy volunteers: comparison with tagging and relevance of gender
    Daniel Augustine
    Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK
    J Cardiovasc Magn Reson 15:8. 2013
    ..We used it to record deformation parameters in healthy adults and compared values to those obtained by tagging...
  12. doi request reprint Relation of preoperative radial artery flow-mediated dilatation to nitric oxide bioavailability in radial artery grafts used in off-pump coronary artery bypass grafting
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Am J Cardiol 103:216-20. 2009
    ..These differences are present and can be identified preoperatively by FMD...
  13. doi request reprint Preterm heart in adult life: cardiovascular magnetic resonance reveals distinct differences in left ventricular mass, geometry, and function
    Adam J Lewandowski
    Oxford Cardiovascular Clinical Research Facility, University of Oxford, Oxford, UK
    Circulation 127:197-206. 2013
    ..In animal studies, this results in an adversely remodeled left ventricle. We determined whether preterm birth is associated with a distinct left ventricular structure and function in humans...
  14. doi request reprint Preoperative sCD40L levels predict risk of atrial fibrillation after off-pump coronary artery bypass graft surgery
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, UK
    Circulation 120:S170-6. 2009
    ..Furthermore, we studied the role of inflammation, endothelial function, and redox state in this relation...
  15. doi request reprint Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital OX3 9DU, Oxford, UK
    Circulation 124:335-45. 2011
    ..We examined the direct effects of atorvastatin on tetrahydrobiopterin-mediated endothelial nitric oxide (NO) synthase coupling in patients with coronary artery disease...
  16. doi request reprint Short-term exposure to exogenous lipids in premature infants and long-term changes in aortic and cardiac function
    Adam J Lewandowski
    Cardiovascular Clinical Research Facility, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
    Arterioscler Thromb Vasc Biol 31:2125-35. 2011
    ..We investigated whether elevated lipids in humans during the critical period of preterm neonatal life have a long-term impact on aortic and myocardial function relevant to adult disease...
  17. pmc Observational study of regional aortic size referenced to body size: production of a cardiovascular magnetic resonance nomogram
    Anne E Davis
    Radcliffe Department of Medicine, Division of Cardiovascular Medicine, John Radcliffe Hospital, Oxford OX3 9DU, UK
    J Cardiovasc Magn Reson 16:9. 2014
    ....
  18. pmc Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Hedley Way, OX3 9DU, Oxford, UK
    Circulation 124:1860-70. 2011
    ..We hypothesized that induction of BH4 synthesis might be an endothelial defense mechanism against inflammation in vascular disease states...
  19. pmc Aortic stiffness and blood pressure variability in young people: a multimodality investigation of central and peripheral vasculature
    Henry Boardman
    aOxford Cardiovascular Clinical Research Facility bOxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK
    J Hypertens . 2016
    ..We used a multimodality approach to determine relations between central and peripheral arterial stiffness and BP variability...
  20. doi request reprint Obese subjects show sex-specific differences in right ventricular hypertrophy
    Oliver J Rider
    From the Oxford Centre for Clinical Magnetic Resonance Research O J R, A J M L, N N, R N, J M F, A P, R B, S N and Oxford Clinical Cardiovascular Research Facility A J L, P L, Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom and William Harvey Research Institute, Queen Mary, University of London, London, United Kingdom S E P
    Circ Cardiovasc Imaging 8:. 2015
    ....
  21. doi request reprint Dynamic release and clearance of circulating microparticles during cardiac stress
    Daniel Augustine
    From the Oxford Cardiovascular Clinical Research Facility, University of Oxford, Oxford, United Kingdom D A, E L, L N, A J L, E F D, P L and Department of Clinical Immunology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom L V A, B F
    Circ Res 114:109-13. 2014
    ..Microparticles are cell-derived membrane vesicles, relevant to a range of biological responses and known to be elevated in cardiovascular disease...
  22. pmc Gender-specific differences in left ventricular remodelling in obesity: insights from cardiovascular magnetic resonance imaging
    Oliver J Rider
    Department of Cardiovascular Medicine, University of Oxford, UK
    Eur Heart J 34:292-9. 2013
    ....
  23. doi request reprint Unique blood pressure characteristics in mother and offspring after early onset preeclampsia
    Merzaka Lazdam
    Oxford Cardiovascular Clinical Research Facility, Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Hypertension 60:1338-45. 2012
    ..These are not evident in mothers and offspring after late-onset preeclampsia or normotensive pregnancy...
  24. doi request reprint Elevated blood pressure in preterm-born offspring associates with a distinct antiangiogenic state and microvascular abnormalities in adult life
    Adam J Lewandowski
    From the Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom A J L, E F D, G Y, J E D, H B, P W, P L Department of Clinical Epidemiology, Nutrition and Biostatistics, Institute of Child Health, University College London, London, United Kingdom A S, A L Department of Paediatrics, John Radcliffe Hospital, Oxford, United Kingdom K M and Department of Vascular Medicine, NIHR Exeter Clinical Research Facility, University of Exeter Medical School, Exeter, United Kingdom A C S
    Hypertension 65:607-14. 2015
    ..The association seems to be mediated through capillary rarefaction and is independent of other cardiovascular structural and functional differences in the offspring. ..
  25. doi request reprint Will Exercise Advice Be Sufficient for Treatment of Young Adults With Prehypertension and Hypertension? A Systematic Review and Meta-Analysis
    Wilby Williamson
    From the Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine W W, A J L, H B, O H, P L, British Heart Foundation Centre on Population Approaches for Non Communicable Disease Prevention, Nuffield Department of Population Health C F, H R, Bodleian Health Care Libraries N R, Department of Primary Care Health Sciences D M C, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences J N, and Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences S G, University of Oxford, Oxford, United Kingdom Institute for Sport, Physical Education and Health Sciences, University of Edinburgh, Edinburgh, United Kingdom P K and Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, United Kingdom H D
    Hypertension 68:78-87. 2016
    ..There is need for continued research to improve age-specific strategies and recommendations for hypertension prevention and management in young adults. ..
  26. doi request reprint "3D fusion" echocardiography improves 3D left ventricular assessment: comparison with 2D contrast echocardiography
    Daniel Augustine
    Radcliffe Department of Medicine, Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
    Echocardiography 32:302-9. 2015
    ..We assessed image quality, endocardial border definition, and cardiac wall motion in patients using 3DFE compared to standard 3D images (3D) and results obtained with contrast echocardiography (2DC)...
  27. doi request reprint Elevated blood pressure in offspring born premature to hypertensive pregnancy: is endothelial dysfunction the underlying vascular mechanism?
    Merzaka Lazdam
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Hypertension 56:159-65. 2010
    ..However, predominant underlying vascular phenotype depends on maternal pathology. Targeting endothelial function may be particularly important for primary prevention after hypertension in pregnancy...
  28. ncbi request reprint Altered plasma versus vascular biopterins in human atherosclerosis reveal relationships between endothelial nitric oxide synthase coupling, endothelial function, and inflammation
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, Oxford, UK
    Circulation 116:2851-9. 2007
    ..We sought to define the relationships between plasma and vascular biopterin levels in patients with coronary artery disease and to determine how BH4 levels affect endothelial function, eNOS coupling, and vascular superoxide production...
  29. pmc Pre-eclampsia and offspring cardiovascular health: mechanistic insights from experimental studies
    Esther F Davis
    Oxford Cardiovascular Clinical Research Facility, Department of Cardiovascular Medicine, University of Oxford, Oxford, UK
    Clin Sci (Lond) 123:53-72. 2012
    ....
  30. pmc Comprehensive multi-modality assessment of regional and global arterial structure and function in adults born preterm
    Henry Boardman
    Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK
    Hypertens Res 39:39-45. 2016
    ....
  31. pmc Early changes in arterial structure and function following statin initiation: quantification by magnetic resonance imaging
    Justin M S Lee
    Department of Cardiovascular Medicine, University of Oxford, United Kingdom
    Atherosclerosis 197:951-8. 2008
    ..50, P<0.001; R(2)=0.22, P<0.05, respectively). Improvements in aortic distensibility and brachial endothelial function that were apparent after 3 months treatment were sustained at the 12-month time point...
  32. ncbi request reprint From gene to epigene-based therapies targeting the vascular endothelium
    Adam J Lewandowski
    Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK
    Curr Vasc Pharmacol 10:125-37. 2012
    ....
  33. ncbi request reprint Images in cardiovascular medicine. Visualization of the ruptured plaque by magnetic resonance imaging
    Frank Wiesmann
    Department of Cardiovascular Medicine, John Radcliffe Hospital, Headley Way, Oxford OX 3 9 DU, UK
    Circulation 108:2542. 2003
  34. pmc Normal variation of magnetic resonance T1 relaxation times in the human population at 1.5 T using ShMOLLI
    Stefan K Piechnik
    Department of Cardiovascular Medicine, Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, UK
    J Cardiovasc Magn Reson 15:13. 2013
    ..We aimed to assess the variability of myocardial T1 relaxation times in the normal human population estimated with recently proposed Shortened Modified Look-Locker Inversion recovery (ShMOLLI) T1 mapping technique...
  35. pmc Prevention of vascular dysfunction after preeclampsia: a potential long-term outcome measure and an emerging goal for treatment
    Merzaka Lazdam
    Department of Cardiovascular Medicine, Oxford Cardiovascular Clinical Research Facility, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    J Pregnancy 2012:704146. 2012
    ..This paper considers the links between cardiovascular disease and preeclampsia and the implication of these findings for refinement of the management of patients whose care is complicated by preeclampsia...
  36. pmc Effect of CPAP on Cardiac Function in Minimally Symptomatic Patients with OSA: Results from a Subset of the MOSAIC Randomized Trial
    Sonya Craig
    Oxford Centre for Respiratory Medicine, Oxford Biomedical Research Centre and Oxford University, Oxford, UK
    J Clin Sleep Med 11:967-73. 2015
    ..The MOSAIC randomized, controlled trial of CPAP for minimally symptomatic OSA assessed the effect of CPAP on myocardial function in a subset of patients...
  37. pmc Association of Maternal Antiangiogenic Profile at Birth With Early Postnatal Loss of Microvascular Density in Offspring of Hypertensive Pregnancies
    Grace Z Yu
    From the Division of Cardiovascular Medicine, Radcliffe Department of Medicine G Z Y, C Y L A, A J L, E F D, L N, A A H Z, L J S, K O B, T K, K M C, P L, Stem Cell Research, Radcliffe Department of Medicine, Nuffield Division of Clinical Laboratory Sciences and National Health Service Blood and Transplant G Z Y, C P K, L N, C T Y, L J S, D A C, S M W, Nuffield Department of Obstetrics and Gynaecology, Medical Sciences Division C Y L A, I G, and Wellcome Trust Centre for Human Genetics A A H Z, T K, University of Oxford, United Kingdom and Peninsula Schools of Medicine and Dentistry, Plymouth University, United Kingdom K O B
    Hypertension 68:749-59. 2016
    ..Degree of postnatal microvessel reduction is proportional to levels of antiangiogenic factors in the maternal circulation at birth. ..
  38. pmc Clinical cardiovascular risk during young adulthood in offspring of hypertensive pregnancies: insights from a 20-year prospective follow-up birth cohort
    Esther F Davis
    Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Oxford, UK
    BMJ Open 5:e008136. 2015
    ..We hypothesised that offspring of hypertensive pregnancies would demonstrate increased clinical levels of hypertension by young adult life, which would be proportional to the severity of the pregnancy complication...
  39. doi request reprint Cardiovascular risk factors in children and young adults born to preeclamptic pregnancies: a systematic review
    Esther Frances Davis
    Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
    Pediatrics 129:e1552-61. 2012
    ..Our objective was to examine evidence for increased cardiovascular risk factors in children exposed to preeclampsia in utero...
  40. ncbi request reprint Patent foramen ovale closure before orthopedic trauma surgery to reduce risk of recurrent systemic fat embolism
    Paul Leeson
    Department of Cardiology, John Radcliffe Hospital, Oxford
    J Trauma 65:467-9. 2008
  41. pmc Uncomplicated obesity is associated with abnormal aortic function assessed by cardiovascular magnetic resonance
    Monique R Robinson
    Oxford Centre for Clinical Magnetic Resonance Research OCMR, Department of Cardiovascular Medicine, University of Oxford, Oxford, UK
    J Cardiovasc Magn Reson 10:10. 2008
    ..We hypothesised that obesity, uncomplicated by other cardiovascular risk factors, is independently associated with aortic function...
  42. doi request reprint Data-driven shape parameterization for segmentation of the right ventricle from 3D+t echocardiography
    Richard V Stebbing
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, United Kingdom Electronic address
    Med Image Anal 21:29-39. 2015
    ..Furthermore, the framework is shown to achieve smaller segmentation errors than a state-of-art commercial semi-automatic RV segmentation package. ..
  43. pmc Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis
    Wilby Williamson
    Division of Cardiovascular Medicine, Cardiovascular Clinical Research Facility, University of Oxford, Oxford, UK
    BMJ Open 5:e007642. 2015
    ..To assess effectiveness of osteoarthritis interventions to promote long-term physical activity behaviour change...
  44. doi request reprint Dynamic microvesicle release and clearance within the cardiovascular system: triggers and mechanisms
    Lisa Ayers
    Oxford Cardiovascular Clinical Research Facility, University of Oxford, Oxford OX3 9DU, U K Department of Clinical and Laboratory Immunology, Oxford University Hospitals NHS Trust, Oxford OX3 7LE, U K
    Clin Sci (Lond) 129:915-31. 2015
    ....
  45. doi request reprint Preeclampsia, prematurity and cardiovascular health in adult life
    Adam J Lewandowski
    Oxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK Faculty of Medicine, University of Ottawa, Ottawa, Canada Electronic address
    Early Hum Dev 90:725-9. 2014
    ..This review discusses the importance of continued research focused on the mechanistic understanding of these cardiovascular alterations in order to develop specific primary prevention strategies. ..
  46. ncbi request reprint Atrial septal endocarditis
    Andrew R J Mitchell
    Department of Echocardiography, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom
    Eur J Echocardiogr 8:48-9. 2007
    ..We present the echocardiography findings from a young man presenting with endocarditis of an abnormal mitral valve in whom endocarditis was demonstrated associated with an atrial septal defect...
  47. ncbi request reprint A transesophageal echocardiography study: traumatic left atrial appendage and left upper pulmonary vein dissection
    Paul Leeson
    Department of Cardiology, John Radcliffe Hospital, Oxford, United Kingdom
    J Am Soc Echocardiogr 20:537.e3-5. 2007
    ..The report summarizes the literature on traumatic injury to the left upper pulmonary vein and left atrial appendage and demonstrates the importance of comprehensive echocardiographic studies to identify unexpected pathology...
  48. ncbi request reprint Suppurative bacterial myocarditis: echocardiographic and pathological findings
    Tania Elias
    Department of Cardiology, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK
    Eur Heart J 29:489. 2008
  49. ncbi request reprint 5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling
    Charalambos Antoniades
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Circulation 114:1193-201. 2006
    ..We hypothesized that 5-MTHF would improve endothelial function by decreasing superoxide and peroxynitrite production and by improving eNOS coupling, mediated by BH4 availability...