Debbie Anne Lawlor

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. doi Triangulation in aetiological epidemiology
    Debbie A Lawlor
    MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK
    Int J Epidemiol . 2017
  2. pmc The Active for Life Year 5 (AFLY5) school-based cluster randomised controlled trial: effect on potential mediators
    Debbie A Lawlor
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK
    BMC Public Health 16:68. 2016
  3. pmc Cross-sectional associations between the screen-time of parents and young children: differences by parent and child gender and day of the week
    Russell Jago
    Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, 8 Priory Road, Bristol BS8 1TZ, England
    Int J Behav Nutr Phys Act 11:54. 2014
  4. pmc The effect of fat mass on educational attainment: examining the sensitivity to different identification strategies
    Stephanie von Hinke Kessler Scholder
    Department of Economics and Related Studies, University of York, York YO10 5DD, United Kingdom
    Econ Hum Biol 10:405-18. 2012
  5. pmc Pregnancy glycaemia and cord-blood levels of insulin and leptin in Pakistani and white British mother-offspring pairs: findings from a prospective pregnancy cohort
    Debbie A Lawlor
    MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Diabetologia 57:2492-500. 2014
  6. pmc DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort
    Eva Morales
    Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, Tyne and Wear, UK
    BMC Res Notes 7:278. 2014
  7. pmc Socioeconomic differences in childhood length/height trajectories in a middle-income country: a cohort study
    Rita Patel
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    BMC Public Health 14:932. 2014
  8. pmc Using latent class analysis to develop a model of the relationship between socioeconomic position and ethnicity: cross-sectional analyses from a multi-ethnic birth cohort study
    Lesley Fairley
    Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
    BMC Public Health 14:835. 2014
  9. pmc Associations between objectively assessed child and parental physical activity: a cross-sectional study of families with 5-6 year old children
    Russell Jago
    Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, 8 Priory Road, Bristol, BS8 1TZ, UK
    BMC Public Health 14:655. 2014
  10. pmc Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    BMC Public Health 14:597. 2014

Collaborators

Detail Information

Publications156 found, 100 shown here

  1. doi Triangulation in aetiological epidemiology
    Debbie A Lawlor
    MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK
    Int J Epidemiol . 2017
    ..We also note the importance, when comparing results, of taking account of differences in the duration and timing of exposures. We provide three examples to illustrate these points...
  2. pmc The Active for Life Year 5 (AFLY5) school-based cluster randomised controlled trial: effect on potential mediators
    Debbie A Lawlor
    School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK
    BMC Public Health 16:68. 2016
    ..This paper aims to determine the effect of the intervention on potential mediators...
  3. pmc Cross-sectional associations between the screen-time of parents and young children: differences by parent and child gender and day of the week
    Russell Jago
    Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, 8 Priory Road, Bristol BS8 1TZ, England
    Int J Behav Nutr Phys Act 11:54. 2014
    ..Greater time spent screen-viewing (SV) has been linked to adverse health outcomes. The aim of this study was to examine whether parental SV time is associated with child SV time on week and weekend days...
  4. pmc The effect of fat mass on educational attainment: examining the sensitivity to different identification strategies
    Stephanie von Hinke Kessler Scholder
    Department of Economics and Related Studies, University of York, York YO10 5DD, United Kingdom
    Econ Hum Biol 10:405-18. 2012
    ..Examining the potential violations of key assumptions of the different approaches and comparing their point estimates, we conclude that fat mass is unlikely to be causally related to academic achievement in adolescence...
  5. pmc Pregnancy glycaemia and cord-blood levels of insulin and leptin in Pakistani and white British mother-offspring pairs: findings from a prospective pregnancy cohort
    Debbie A Lawlor
    MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Diabetologia 57:2492-500. 2014
    ..To determine the extent to which gestational fasting and postload levels of glucose explain differences in infant fat mass between UK-born Pakistani and white British infants...
  6. pmc DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort
    Eva Morales
    Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, Tyne and Wear, UK
    BMC Res Notes 7:278. 2014
    ..Pyrosequencing was used for validation of the top associated locus and for replication in 170 non-overlapping mother-offspring pairs from the ALSPAC cohort...
  7. pmc Socioeconomic differences in childhood length/height trajectories in a middle-income country: a cohort study
    Rita Patel
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    BMC Public Health 14:932. 2014
    ..Socioeconomic disadvantage is associated with shorter adult stature. Few studies have examined socioeconomic differences in stature from birth to childhood and the mechanisms involved, particularly in middle-income former Soviet settings...
  8. pmc Using latent class analysis to develop a model of the relationship between socioeconomic position and ethnicity: cross-sectional analyses from a multi-ethnic birth cohort study
    Lesley Fairley
    Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
    BMC Public Health 14:835. 2014
    ..SEP and ethnicity are strongly associated, however not all measures of SEP may be appropriate for all ethnic groups...
  9. pmc Associations between objectively assessed child and parental physical activity: a cross-sectional study of families with 5-6 year old children
    Russell Jago
    Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, 8 Priory Road, Bristol, BS8 1TZ, UK
    BMC Public Health 14:655. 2014
    ....
  10. pmc Skin pigmentation, sun exposure and vitamin D levels in children of the Avon Longitudinal Study of Parents and Children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    BMC Public Health 14:597. 2014
    ..Additionally, we aimed to examine the influence of pigmentation on personal behaviour towards sunlight exposure and the effects of this behaviour on vitamin D...
  11. pmc Evaluation of the impact of universal testing for gestational diabetes mellitus on maternal and neonatal health outcomes: a retrospective analysis
    Diane Farrar
    Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK
    BMC Pregnancy Childbirth 14:317. 2014
    ..This paper describes an evaluation of the impact of a change in policy from selective risk factor based offering, to universal offering of an oral glucose tolerance test (OGTT) to identify women with GDM on maternal and neonatal outcomes...
  12. pmc Role of endogenous oestrogen in aetiology of coronary heart disease: analysis of age related trends in coronary heart disease and breast cancer in England and Wales and Japan
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:311-2. 2002
  13. pmc The challenges of evaluating environmental interventions to increase population levels of physical activity: the case of the UK National Cycle Network
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:96-101. 2003
  14. pmc Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS7 8QA, UK
    Br J Cancer 91:512-8. 2004
    ..07 (0.94, 1.22). We conclude that smoking prior to the birth of a first child is not associated with increased risk of breast cancer...
  15. ncbi Leptin and coronary heart disease risk: prospective case control study of British women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Obesity (Silver Spring) 15:1694-701. 2007
    ..Our objective was to examine the association of serum leptin levels with CHD in a prospective study of women...
  16. pmc The association of fasting insulin, glucose, and lipids with bone mass in adolescents: findings from a cross-sectional study
    Debbie A Lawlor
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:2068-76. 2012
    ..It is unclear whether variation in insulin resistance mediates the positive association of fat mass with bone mass in children/adolescents...
  17. pmc Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    J Epidemiol Community Health 57:134-40. 2003
    ..To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women...
  18. ncbi (Mis)use of factor analysis in the study of insulin resistance syndrome
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Am J Epidemiol 159:1013-8. 2004
    ..However, to date none of the studies has adopted this approach, and other statistical approaches and study designs are likely to provide greater understanding of the syndrome...
  19. ncbi Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Diabet Med 22:808-11. 2005
    ..To examine the association of milk consumption with insulin resistance and the metabolic syndrome...
  20. ncbi The effect of physical activity advice given in routine primary care consultations: a systematic review
    D A Lawlor
    Department of Social Medicine, University of Bristol
    J Public Health Med 23:219-26. 2001
    ..Brief advice in primary care to adopt a more active lifestyle may be similarly effective. The aim of this review is to determine the effect of advice given in routine primary care consultations on levels of physical activity...
  21. pmc Rurality, deprivation, and excess winter mortality: an ecological study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol UK
    J Epidemiol Community Health 56:373-4. 2002
  22. pmc Birth weight of offspring and insulin resistance in late adulthood: cross sectional survey
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:359. 2002
    ..To investigate the association between birth weight of offspring and mothers' insulin resistance in late adulthood...
  23. ncbi Secular trends in mortality by stroke subtype in the 20th century: a retrospective analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Lancet 360:1818-23. 2002
    ....
  24. ncbi Systematic review of the epidemiologic and trial evidence of an association between antidepressant medication and breast cancer
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Clin Epidemiol 56:155-63. 2003
    ..We conclude that epidemiologic evidence does not support an association between antidepressant use and breast cancer...
  25. pmc Association between falls in elderly women and chronic diseases and drug use: cross sectional study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 327:712-7. 2003
    ..To assess the associations between having had a fall and chronic diseases and drug use in elderly women...
  26. pmc Birth weight is inversely associated with coronary heart disease in post-menopausal women: findings from the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 58:120-5. 2004
    ....
  27. ncbi Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors. British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Thromb Haemost 93:955-63. 2005
    ..We conclude that fibrinogen and CRP predict CHD but may not be causally related to it...
  28. ncbi The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyltransferase
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol Medical School, Bristol, United Kingdom
    Am J Epidemiol 161:1081-8. 2005
    ..These findings provide some support for the suggestion that the relation between obesity and diabetes is, at least in part, mediated by liver pathology...
  29. doi The developmental origins of health and disease: where do we go from here?
    Debbie A Lawlor
    MRC Centre of Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Epidemiology 19:206-8. 2008
    ....
  30. ncbi Caring for the health of the public: cross sectional study of the activities of UK public health departments
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Public Health 116:102-5. 2002
    ....
  31. pmc Smoking and ill health: does lay epidemiology explain the failure of smoking cessation programs among deprived populations?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, England
    Am J Public Health 93:266-70. 2003
    ..Health promotion initiatives designed to reduce smoking among members of these groups may continue to fail unless the general health and life chances of such individuals are first improved...
  32. pmc Performance of the WHO Rose angina questionnaire in post-menopausal women: are all of the questions necessary?
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 57:538-41. 2003
    ..To assess the performance of a shortened version of the Rose angina questionnaire focusing on exertional chest pain...
  33. pmc Association of insulin resistance with depression: cross sectional findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 327:1383-4. 2003
  34. ncbi Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabetologia 47:195-203. 2004
    ..The aim of this study was to assess the associations of lung function with insulin resistance and Type 2 diabetes...
  35. pmc Association between self-reported childhood socioeconomic position and adult lung function: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Thorax 59:199-203. 2004
    ..A study was undertaken to assess the associations between indicators of early life socioeconomic position and lung function in older adulthood...
  36. pmc Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British regional heart study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    J Epidemiol Community Health 58:700-4. 2004
    ..To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT)...
  37. pmc Socioeconomic position and hormone replacement therapy use: explaining the discrepancy in evidence from observational and randomized controlled trials
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS7 8QA, UK
    Am J Public Health 94:2149-54. 2004
    ..We assessed the association between life-course socioeconomic status or position (SEP) and hormone replacement therapy (HRT)...
  38. pmc Is being overweight associated with behavioural problems in childhood and adolescence? Findings from the Mater-University study of pregnancy and its outcomes
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Arch Dis Child 90:692-7. 2005
    ..To examine the associations between being overweight and behavioural problems at ages 5 and 14...
  39. pmc Early life predictors of childhood intelligence: evidence from the Aberdeen children of the 1950s study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:656-63. 2005
    ..To identify the early life predictors of childhood intelligence...
  40. ncbi Sex differences in the association between birth weight and total cholesterol. A meta-analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, United Kingdom
    Ann Epidemiol 16:19-25. 2006
    ..Determine whether a sex difference exists in the association between birth weight and total cholesterol later in life...
  41. pmc Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    Thorax 60:851-8. 2005
    ....
  42. ncbi Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
    J Clin Endocrinol Metab 90:5677-83. 2005
    ..Many observers thus already consider adiponectin to be a major part of the "common soil" underpinning diabetes and vascular disease...
  43. ncbi Birth weight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: findings from the Aberdeen Children of the 1950s prospective cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, BS8 2PR, United Kingdom
    Circulation 112:1414-8. 2005
    ....
  44. ncbi A comparison of the association between socioeconomic position and cardiovascular disease risk factors in three age cohorts of Australian women: findings from the Australian Longitudinal Study on Women's Health
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, UK
    J Public Health (Oxf) 27:378-87. 2005
    ..To assess the associations between three measurements of socioeconomic position (SEP) -- education, occupation and ability to cope on available income -- and cardiovascular risk factors in three age cohorts of Australian women...
  45. ncbi The association of the PON1 Q192R polymorphism with complications and outcomes of pregnancy: findings from the British Women's Heart and Health cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 20:244-50. 2006
    ..02, 1.39]. Our findings provide some further evidence to suggest that PON1 Q192R is associated with preterm birth; they invite further investigation of both maternal and fetal genotype for PON1 Q192R in relation to preterm birth...
  46. pmc Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    PLoS Med 4:e263. 2007
    ..Our aim was to determine the independent associations of fasting insulin, glucose, and glycated haemoglobin with coronary heart disease and stroke in older women...
  47. pmc Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable
    Debbie A Lawlor
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    PLoS Med 5:e33. 2008
    ..If true, this would result in the obesity epidemic progressing across generations irrespective of environmental or genetic changes. It is therefore important to robustly test this hypothesis...
  48. doi Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    J Intern Med 269:525-37. 2011
    ..We used genetic variants that are robustly associated with adiposity to examine the causal association of adiposity with psychological distress...
  49. pmc Association of maternal diabetes mellitus in pregnancy with offspring adiposity into early adulthood: sibling study in a prospective cohort of 280,866 men from 248,293 families
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN, UK
    Circulation 123:258-65. 2011
    ..It is unclear whether it is associated with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or shared familial characteristics...
  50. pmc Obstetrician-assessed maternal health at pregnancy predicts offspring future health
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, United Kingdom
    PLoS ONE 2:e666. 2007
    ..We aimed to examine the association between obstetrician assessment of maternal physical health at the time of pregnancy and offspring cardiovascular disease risk...
  51. pmc The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    PLoS ONE 3:e3011. 2008
    ..Our objective was to examine the association between CRP genetic variant +1444C>T (rs1130864) and CHD risk in the largest study to date of this association...
  52. pmc Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol BS8 2BN, UK
    BMJ 341:c6224. 2010
    ..To examine the prospective associations between body mass index (BMI), waist circumference, and fat mass in childhood and cardiovascular risk factors at age 15-16...
  53. pmc Familial associations of adiposity: findings from a cross-sectional study of 12,181 parental-offspring trios from Belarus
    Rita Patel
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 6:e14607. 2011
    ..We aimed to examine these associations in one of the largest studies to date using data from a low-middle income country that has recently undergone a major political and economic transition...
  54. pmc Survival with treated and well-controlled blood pressure: findings from a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 6:e17792. 2011
    ..To compare survival and incident cardiovascular disease between normotensive, untreated hypertensive, treated and poorly-controlled hypertensive and treated and well-controlled hypertensive adults...
  55. pmc Cardiovascular biomarkers and vascular function during childhood in the offspring of mothers with hypertensive disorders of pregnancy: findings from the Avon Longitudinal Study of Parents and Children
    Debbie Anne Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK
    Eur Heart J 33:335-45. 2012
    ....
  56. pmc Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Int J Epidemiol 42:97-110. 2013
    ..Details of how to access these data are provided in this cohort profile...
  57. pmc The association of 25-hydroxyvitamin D3 and D2 with behavioural problems in childhood
    Anna Maija Tolppanen
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e40097. 2012
    ..Concentrations of 1,25-dihydroxyvitamin D(3) (the active vitamin D(3) metabolite) have been associated with openness and extrovert behaviour, but 25(OH)D concentrations have not been associated with behavioural problems in humans...
  58. pmc Serum 25-hydroxyvitamin D3 and D2 and non-clinical psychotic experiences in childhood
    Anna Maija Tolppanen
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e41575. 2012
    ....
  59. pmc Associations of maternal 25-hydroxyvitamin D in pregnancy with offspring cardiovascular risk factors in childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children
    Dylan M Williams
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Heart 99:1849-56. 2013
    ..We examined associations of maternal total 25-hydroxyvitamin D (25(OH)D) in pregnancy with offspring cardiovascular risk factors assessed in childhood and adolescence...
  60. pmc Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: a cross-sectional study of 1874 general population adolescents
    Debbie A Lawlor
    Medical Research Council Integrative Epidemiology Unit D A L, C M W, E A, A F, L D H and School of Social and Community Medicine D A L, C M W, E A, A F, L D H, University of Bristol, Bristol BS8 2BN, United Kingdom University Hospitals Bristol National Health Service Foundation Trust M C, Bristol BS1 3NU, United Kingdom Institute of Cellular Medicine C D, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom and Institute of Cardiovascular and Medical Sciences N S, BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom
    J Clin Endocrinol Metab 99:E410-7. 2014
    ..The impact of adolescent nonalcoholic fatty liver disease (NAFLD) on health, independent of fat mass, is unclear...
  61. doi Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN Bristol, UK
    Eur Heart J 34:2519-28. 2013
    ..To explore the causal effect of long-term alcohol consumption on coronary heart disease risk factors...
  62. pmc Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol
    Philip A I Guthrie
    Bristol Genetic Epidemiology Laboratory BGEL, MRC Centre for Causal Analyses in Translational Epidemiology MRC CAiTE, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Clifton BS8 2BN, UK
    Gene 499:8-13. 2012
    ....
  63. pmc Associations of mortality with own height using son's height as an instrumental variable
    David Carslake
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, School of Social and Community Medicine, University of Bristol, United Kingdom
    Econ Hum Biol 11:351-9. 2013
    ....
  64. pmc Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMC Med Genet 13:90. 2012
    ..These associations could be explained by confounding...
  65. doi Maternal adiposity--a determinant of perinatal and offspring outcomes?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Nat Rev Endocrinol 8:679-88. 2012
    ..To date, little high-quality human evidence exists that any of these effects are mediated by epigenetic mechanisms, but approaches to appropriately test this possibility are being developed...
  66. pmc Association of maternal vitamin D status during pregnancy with bone-mineral content in offspring: a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol UK
    Lancet 381:2176-83. 2013
    ..Maternal vitamin D status in pregnancy is a suggested determinant of bone-mineral content (BMC) in offspring, but has been assessed in small studies. We investigated this association in a large prospective study...
  67. doi The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition--an old hypothesis with new importance?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Int J Epidemiol 42:7-29. 2013
    ..I conclude with a discussion about the future research and policy implications of evidence to date in this field...
  68. doi Risk factors for variation in 25-hydroxyvitamin D₃ and D₂ concentrations and vitamin D deficiency in children
    Anna Maija Tolppanen
    Medical Research Council, Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, 15 23 Oakfield Grove, Clifton, Bristol BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:1202-10. 2012
    ..Suboptimal vitamin D status is common and associated with adverse health outcomes...
  69. pmc The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trial
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Trials 12:181. 2011
    ....
  70. pmc Physical activity as a treatment for depression: the TREAD randomised trial protocol
    Helen Baxter
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Trials 11:105. 2010
    ..The aim of this paper is to describe the protocol for a randomised, controlled trial (RCT) designed to evaluate an intervention developed to increase physical activity as a treatment for depression within primary care...
  71. pmc Geographical variation in cardiovascular incidence: results from the British Women's Heart and Health Study
    Lois G Kim
    Department of Medical Statistics Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    BMC Public Health 10:696. 2010
    ..Prevalence of cardiovascular disease (CVD) in women shows regional variations not explained by common risk factors. Analysis of CVD incidence will provide insight into whether there is further divergence between regions with increasing age...
  72. pmc Overweight and obesity knowledge prior to pregnancy: a survey study
    Marloes Dekker Nitert
    School of Medicine, Royal Brisbane Clinical School, The University of Queensland, Brisbane, Australia
    BMC Pregnancy Childbirth 11:96. 2011
    ..Knowledge about increased risks in overweight and obese women could contribute to successful prevention strategies and the aim of this study is to assess current levels of knowledge in a pregnant population...
  73. pmc Associations of maternal pre-pregnancy obesity and excess pregnancy weight gains with adverse pregnancy outcomes and length of hospital stay
    Abdullah A Mamun
    School of Population Health, The University of Queensland, Brisbane, Australia
    BMC Pregnancy Childbirth 11:62. 2011
    ....
  74. pmc Reasons for and consequences of missed appointments in general practice in the UK: questionnaire survey and prospective review of medical records
    Richard D Neal
    North Wales Clinical School, Department of General Practice, University of Cardiff, Wrexham Technology Park, Wrexham LL13 7YP, UK
    BMC Fam Pract 6:47. 2005
    ..Secondary aims are to compare psychological morbidity, and the previous appointments with GPs between subjects and a comparison group...
  75. pmc Do British travel agents provide adequate health advice for travellers?
    D A Lawlor
    Department of Social Medicine, University of Bristol
    Br J Gen Pract 50:567-8. 2000
    ..This study, using covert researchers, suggests this potential is not being fully utilised...
  76. pmc Sex matters: secular and geographical trends in sex differences in coronary heart disease mortality
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 323:541-5. 2001
    ..To examine secular trends and geographical variations in sex differences in mortality from coronary heart disease and investigate how these relate to distributions in risk factors...
  77. pmc Aspirin use for the prevention of cardiovascular disease: the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
    Br J Gen Pract 51:743-5. 2001
    ..Improvements in this area of medical practice are both necessary and feasible...
  78. ncbi Agreement between measured and self-reported weight in older women. Results from the British Women's Heart and Health Study
    Debbie Anne Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Age Ageing 31:169-74. 2002
    ..The cultural pressures that may cause the tendency among younger women to underestimate their weight, particularly when they are overweight, may operate differently in older women...
  79. pmc Is housework good for health? Levels of physical activity and factors associated with activity in elderly women. Results from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 56:473-8. 2002
    ..To determine the prevalence of achieving new recommended levels of physical activity, the types of activity involved, and their determinants among elderly British women...
  80. ncbi The association between components of adult height and Type II diabetes and insulin resistance: British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Diabetologia 45:1097-106. 2002
    ..The aim of this study was to investigate the associations between components of adult height (leg length, trunk length, ratio of leg to trunk length) and Type II (non-insulin-dependent) diabetes mellitus and insulin resistance...
  81. pmc Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British women's heart and health study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:805. 2002
    ..To assess the associations between childhood and adulthood social class and insulin resistance...
  82. ncbi Is there a sex difference in the association between birth weight and systolic blood pressure in later life? Findings from a meta-regression analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, United Kingdom
    Am J Epidemiol 156:1100-4. 2002
    ..These findings suggest that reports of sex differences in the association between birth weight and blood pressure are chance findings...
  83. ncbi Life course influences on insulin resistance: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, U K
    Diabetes Care 26:97-103. 2003
    ..To assess the independent associations of a broad range of early life risk factors and adult obesity with adult insulin resistance...
  84. ncbi Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart St
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 107:1260-4. 2003
    ..Parity is associated with coronary heart disease (CHD) risk. In the present study, we assessed the associations between number of children and CHD in both women and men...
  85. ncbi Association between leg length and offspring birthweight: partial explanation for the trans-generational association between birthweight and cardiovascular disease: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 17:148-55. 2003
    ....
  86. pmc Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:462-3. 2003
  87. pmc Associations of adult measures of childhood growth with breast cancer: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Br J Cancer 89:81-7. 2003
    ..93, 1.80). These associations were all independent of each other and other potential confounding factors and are likely to reflect different mechanisms by which factors operating prenatally and prepubertally influence breast cancer risk...
  88. pmc Teenage pregnancy rates: high compared with where and when?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J R Soc Med 97:121-3. 2004
  89. pmc Temperature at birth, coronary heart disease, and insulin resistance: cross sectional analyses of the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Heart 90:381-8. 2004
    ..To assess the association of mean outdoor temperature around the time of birth with insulin resistance and coronary heart disease in later life...
  90. ncbi Commentary: the art and science of epidemiology: governed by the seasons?
    D A Lawlor
    University of Bristol, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    Int J Epidemiol 33:144-6. 2004
  91. ncbi Hyperinsulinaemia and increased risk of breast cancer: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Cancer Causes Control 15:267-75. 2004
    ..To assess the association between fasting insulin levels and breast cancer...
  92. ncbi Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Lancet 363:1724-7. 2004
  93. ncbi Commentary: the hormone replacement-coronary heart disease conundrum: is this the death of observational epidemiology?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Int J Epidemiol 33:464-7. 2004
  94. pmc Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Heart 90:745-9. 2004
    ..To assess the associations between components of adult height and coronary heart disease (CHD) in postmenopausal women...
  95. pmc The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    BMC Genet 5:17. 2004
    ..We have examined the association of the PON1 Q192R polymorphism with CHD in a large cohort of British women and combined the results from our cohort study with those from all other published studies...
  96. ncbi The metabolic syndrome and coronary heart disease in older women: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabet Med 21:906-13. 2004
    ..To compare two proposed definitions of the metabolic syndrome and to determine the clinical importance of the syndrome with respect to its association with coronary heart disease (CHD)...
  97. pmc Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, England
    Am J Public Health 94:1386-92. 2004
    ..We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women...
  98. ncbi The challenge of secondary prevention for coronary heart disease in older patients: findings from the British Women's Heart and Health Study and the British Regional Heart Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
    Fam Pract 21:582-6. 2004
    ..Secondary prevention of coronary heart disease (CHD) among older individuals is associated with considerable benefit...
  99. ncbi Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
    Circulation 110:2417-23. 2004
    ..We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age...