M Kumari

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Effects of moderate and vigorous physical activity on heart rate variability in a British study of civil servants
    Kirsten L Rennie
    Department of Epidemiology and Public Health, University College London, London, United Kingdom
    Am J Epidemiol 158:135-43. 2003
  2. ncbi request reprint Minireview: mechanisms by which the metabolic syndrome and diabetes impair memory
    M Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London
    J Gerontol A Biol Sci Med Sci 55:B228-32. 2000
  3. ncbi request reprint Biological predictors of change in functioning in the Whitehall II study
    Meena Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK
    Ann Epidemiol 14:250-7. 2004
  4. pmc Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies
    P J Talmud
    Centre for Cardiovascular Genetics, Department of Medicine, University College London, 5 University St, London, WC1E 6JF, UK
    Diabetologia 54:1710-9. 2011
  5. pmc Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study
    D Gimeno
    International Institute for Society and Health, Department of Epidemiology and Public Health, UCL Medical School, London, UK
    Psychol Med 39:413-23. 2009
  6. ncbi request reprint Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
    J S Yudkin
    Department of Medicine, Centre for Diabetes and Cardiovascular Risk, University College London Medical School, G Block, Archway Wing, Whittington Hospital, Archway Road, London, UK
    Atherosclerosis 148:209-14. 2000
  7. ncbi request reprint Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study
    E J Brunner
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, England
    Circulation 106:2659-65. 2002
  8. ncbi request reprint Social determinants of von willebrand factor: the Whitehall II study
    M Kumari
    Department of Epidemiology and Public Health, Royal Free and University College London Medical School, England
    Arterioscler Thromb Vasc Biol 20:1842-7. 2000
  9. ncbi request reprint APOE polymorphism, socioeconomic status and cognitive function in mid-life--the Whitehall II longitudinal study
    J H Zhao
    Dept of Epidemiology and Public Health, International Centre for Health and Society, 1 19 Torrington Place, London WC1E 6BT, UK
    Soc Psychiatry Psychiatr Epidemiol 40:557-63. 2005
  10. doi request reprint Maternal separation in childhood and diurnal cortisol patterns in mid-life: findings from the Whitehall II study
    M Kumari
    Department of Epidemiology and Public Health, University College London, UK
    Psychol Med 43:633-43. 2013

Detail Information

Publications33

  1. ncbi request reprint Effects of moderate and vigorous physical activity on heart rate variability in a British study of civil servants
    Kirsten L Rennie
    Department of Epidemiology and Public Health, University College London, London, United Kingdom
    Am J Epidemiol 158:135-43. 2003
    ..Vigorous activity was associated with higher HRV, representing a possible mechanism by which physical activity reduces coronary heart disease risk...
  2. ncbi request reprint Minireview: mechanisms by which the metabolic syndrome and diabetes impair memory
    M Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London
    J Gerontol A Biol Sci Med Sci 55:B228-32. 2000
    ....
  3. ncbi request reprint Biological predictors of change in functioning in the Whitehall II study
    Meena Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK
    Ann Epidemiol 14:250-7. 2004
    ..To examine whether risk factors for CHD are related to change in functioning independent of the presence or development of disease...
  4. pmc Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies
    P J Talmud
    Centre for Cardiovascular Genetics, Department of Medicine, University College London, 5 University St, London, WC1E 6JF, UK
    Diabetologia 54:1710-9. 2011
    ..We quantified the effect of ADRA2A (encoding α-2 adrenergic receptor) variants on metabolic traits and type 2 diabetes risk, as reported in four studies...
  5. pmc Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study
    D Gimeno
    International Institute for Society and Health, Department of Epidemiology and Public Health, UCL Medical School, London, UK
    Psychol Med 39:413-23. 2009
    ..The present study sought to assess whether C-reactive protein and interleukin-6 predict cognitive symptoms of depression or whether these symptoms predict inflammatory markers...
  6. ncbi request reprint Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?
    J S Yudkin
    Department of Medicine, Centre for Diabetes and Cardiovascular Risk, University College London Medical School, G Block, Archway Wing, Whittington Hospital, Archway Road, London, UK
    Atherosclerosis 148:209-14. 2000
    ..Thus we propose a role for IL-6 in the pathogenesis of CHD through a combination of autocrine, paracrine and endocrine mechanisms. This hypothesis lends itself to testing using interventions to influence IL-6 secretion and actions...
  7. ncbi request reprint Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study
    E J Brunner
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, England
    Circulation 106:2659-65. 2002
    ..We examine reversibility and the power of psychosocial and behavioral factors to explain the neuroendocrine adaptations that accompany MS...
  8. ncbi request reprint Social determinants of von willebrand factor: the Whitehall II study
    M Kumari
    Department of Epidemiology and Public Health, Royal Free and University College London Medical School, England
    Arterioscler Thromb Vasc Biol 20:1842-7. 2000
    ..These data are consistent with the hypothesis that endothelial dysfunction is part of the explanation for social inequalities in cardiovascular disease...
  9. ncbi request reprint APOE polymorphism, socioeconomic status and cognitive function in mid-life--the Whitehall II longitudinal study
    J H Zhao
    Dept of Epidemiology and Public Health, International Centre for Health and Society, 1 19 Torrington Place, London WC1E 6BT, UK
    Soc Psychiatry Psychiatr Epidemiol 40:557-63. 2005
    ....
  10. doi request reprint Maternal separation in childhood and diurnal cortisol patterns in mid-life: findings from the Whitehall II study
    M Kumari
    Department of Epidemiology and Public Health, University College London, UK
    Psychol Med 43:633-43. 2013
    ..Evidence for an association of the diurnal cortisol rhythm with maternal separation in humans is equivocal...
  11. pmc Would raising the total cholesterol diagnostic cut-off from 7.5 mmol/L to 9.3 mmol/L improve detection rate of patients with monogenic familial hypercholesterolaemia?
    M Futema
    Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, The Rayne Building, University College London, London, WC1E 6JF, UK
    Atherosclerosis 239:295-8. 2015
    ..Given that an overall detection rate of 25% is considered economically acceptable, these data suggest that a diagnostic TC cut-off of 8.6 mmol/L, rather than 9.3 mmol/L would be clinically useful for FH in the general population. ..
  12. pmc Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men
    G Ken-Dror
    Centre for Cardiovascular Genetics, BHF Laboratories, The Rayne Building, Department of Medicine, Royal Free and University College Medical School, London, UK
    J Thromb Haemost 8:2394-403. 2010
    ..We examined whether F7 tagging SNPs (tSNPs) and haplotypes were associated with FVII levels, coagulation activation markers (CAMs) and CHD risk in two cohorts of UK men...
  13. ncbi request reprint Social, behavioral, and metabolic determinants of plasma viscosity in the Whitehall II Study
    Meena Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, London, UK
    Ann Epidemiol 15:398-404. 2005
    ..To examine the social, biological, and metabolic associations of plasma viscosity in a large epidemiological study...
  14. doi request reprint Work stress and coronary heart disease: what are the mechanisms?
    Tarani Chandola
    Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Eur Heart J 29:640-8. 2008
    ..To determine the biological and behavioural factors linking work stress with coronary heart disease (CHD)...
  15. pmc A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohort
    Jane E Ferrie
    Internationale Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, London, UK
    Sleep 30:1659-66. 2007
    ..We investigated associations of sleep duration and change in sleep duration with all-cause, cardiovascular, and non-cardiovascular mortality...
  16. doi request reprint Psychological coping styles and cortisol over the day in healthy older adults
    Katie O'Donnell
    Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Psychoneuroendocrinology 33:601-11. 2008
    ..The results indicate that adaptive coping styles are related to low levels of cortisol over the day, suggesting that neuroendocrine pathways may partly mediate relationships between psychological coping and health...
  17. doi request reprint Effects of socioeconomic position on inflammatory and hemostatic markers: a life-course analysis in the 1958 British birth cohort
    Faiza Tabassum
    Department of Epidemiology and Public Health, University College London, London, United Kingdom
    Am J Epidemiol 167:1332-41. 2008
    ..Risk exposure related to SEP accumulates across the life course and contributes to raised levels of fibrinogen and C-reactive protein, while childhood SEP influences hemostatic markers more than does adult SEP...
  18. ncbi request reprint Social and psychosocial influences on inflammatory markers and vascular function in civil servants (the Whitehall II study)
    Harry Hemingway
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, London, United Kingdom
    Am J Cardiol 92:984-7. 2003
    ..In a sample of 283 nonsmokers, we found that social position was inversely associated with interleukin-6 and C-reactive protein and that participants with mild depression had impaired endothelial function...
  19. doi request reprint Social differences in insulin-like growth factor-1: findings from a British birth cohort
    Meena Kumari
    International Institute for Society and Health, University College London, London, UK
    Ann Epidemiol 18:664-70. 2008
    ..Our aim is to examine whether there are social differences in IGF-1 in a cohort of participants between 44 and 45 years of age...
  20. pmc The relationship between alcohol consumption and cortisol secretion in an aging cohort
    Ellena Badrick
    Department of Epidemiology and Public Health, 1 19 Torrington Place, University College London, London WC1E 6BT, United Kingdom
    J Clin Endocrinol Metab 93:750-7. 2008
    ..Evidence for an association between alcohol consumption and activity of the hypothalamic-pituitary-adrenal (HPA) axis is inconclusive...
  21. pmc Cross-sectional versus prospective associations of sleep duration with changes in relative weight and body fat distribution: the Whitehall II Study
    Saverio Stranges
    Cardiovascular Medicine and Epidemiology Group, Clinical Sciences Research Institute, University of Warwick Medical School, Coventry, England
    Am J Epidemiol 167:321-9. 2008
    ..23, 1.12), nor with the incidence of obesity (odds ratio(adjusted) = 1.05, 95% CI: 0.60, 1.82). There is no temporal relation between short duration of sleep and future changes in measures of body weight and central adiposity...
  22. ncbi request reprint Neuroendocrine and inflammatory factors associated with positive affect in healthy men and women: the Whitehall II study
    Andrew Steptoe
    Department of Epidemiology and Public Health, University College London, London, United Kingdom
    Am J Epidemiol 167:96-102. 2008
    ..These results confirm findings from smaller studies relating cortisol with positive affect while suggesting that in women, positive affect is associated with reduced levels of inflammatory markers...
  23. ncbi request reprint The menopausal transition was associated in a prospective study with decreased health functioning in women who report menopausal symptoms
    Meena Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, Royal Free and University College London Medical School, 1 19 Torrington Place, London WC1 6BT, UK
    J Clin Epidemiol 58:719-27. 2005
    ..To examine change in health functioning as women progress through the menopausal transition...
  24. ncbi request reprint Prospective study of social and other risk factors for incidence of type 2 diabetes in the Whitehall II study
    Meena Kumari
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, England
    Arch Intern Med 164:1873-80. 2004
    ..Social inequalities in the incidence of type 2 diabetes and the relation of health behaviors and psychosocial factors to the incidence of type 2 diabetes are not well established...
  25. ncbi request reprint Association of sleep quality and free time leisure activities in Japanese and British civil servants
    Ali Nasermoaddeli
    Department of Welfare Promotion and Epidemiology, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan
    J Occup Health 47:384-90. 2005
    ..46-0.80) and 0.71 (95%CI; 0.56-0.90) for Japanese and British subjects, respectively). Our findings suggest that engagement in social leisure activities is associated with better sleep quality and consequently better general well-being...
  26. ncbi request reprint Diabetes and cognitive function in a middle-aged cohort: findings from the Whitehall II study
    Meena Kumari
    Department of Epidemiology and Public Health, International Centre for Health and Society, London, UK
    Neurology 65:1597-603. 2005
    ..To compare cognitive performance in those with diabetes, impaired glucose tolerance, and normoglycemia in a middle-aged cohort...
  27. ncbi request reprint The relationship between smoking status and cortisol secretion
    Ellena Badrick
    Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom
    J Clin Endocrinol Metab 92:819-24. 2007
    ..Evidence for an association of smoking status with cortisol secretion is mixed...
  28. ncbi request reprint Chronic stress accelerates atherosclerosis in the apolipoprotein E deficient mouse
    Meena Kumari
    Department of Epidemiology and Public Health, International Centre for Health and Society, London, UK
    Stress 6:297-9. 2003
    ..These data suggest that chronic mild stress can induce or accelerate the development of atherosclerosis...
  29. ncbi request reprint Lifecourse influences on health among British adults: effects of region of residence in childhood and adulthood
    David P Strachan
    Division of Community Health Sciences, St George s University of London, Cranmer Terrace, London, UK
    Int J Epidemiol 36:522-31. 2007
    ..We examined inter-regional migrants in Britain to evaluate the relative importance of early and recent exposures for adult cardiorespiratory risk factors, mental ill-health and sensory function...
  30. pmc Gender-specific associations of short sleep duration with prevalent and incident hypertension: the Whitehall II Study
    Francesco P Cappuccio
    Clinical Sciences Research Institute, Warwick Medical School, Coventry, United Kingdom
    Hypertension 50:693-700. 2007
    ..42 [95% CI: 0.94 to 2.16]; odds ratio: 1.31 [95% CI: 0.65 to 2.63], respectively). Sleep deprivation may produce detrimental cardiovascular effects among women...
  31. ncbi request reprint Life-course influences on health in British adults: effects of socio-economic position in childhood and adulthood
    Chris Power
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London, UK
    Int J Epidemiol 36:532-9. 2007
    ..We assess whether childhood SEP influences disease risk in mid-life, separately from the effect of adult position, and establish how associations vary across multiple measures of disease risk...
  32. pmc Vitamin D status in United States war veterans
    Meena Kumari
    Endocr Pract 14:127-8. 2008
  33. ncbi request reprint Effect of ethanol on lipid-mediated transfection of primary cortical neurons
    Antje Anji
    Department of Anatomy and Physiology, CVM, Kansas State University, Manhattan 66506, USA
    Ann N Y Acad Sci 993:95-102; discussion 123-4. 2003
    ..These data suggest that perhaps ethanol treatment of fetal cortical neurons improved the DNA uptake and/or increased the expression of the reporter genes...