Sarah L Kempster
Affiliation: University of Cambridge
- Developmental control of the Nlrp6 inflammasome and a substrate, IL-18, in mammalian intestineSarah L Kempster
Dept of Obstetrics and Gynaecology, Univ of Cambridge, Box 223, Cambridge, CB2 0SW, United Kingdom
Am J Physiol Gastrointest Liver Physiol 300:G253-63. 2011....
- Paraoxonase-3, a putative circulating antioxidant, is systemically up-regulated in late gestation in the fetal rat, sheep, and humanGusztav Belteki
Department of Obstetrics and Gynaecology, University of Cambridge, and Neonatal Intensive Care Unit, Addenbrooke s Hospital, Box 223, Cambridge CB2 0SW, United Kingdom
J Clin Endocrinol Metab 95:3798-805. 2010..Although prematurity is associated with oxidative stress, no effective antioxidant therapy has yet been identified...
- Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in miceSarah L Kempster
Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK
Am J Physiol Endocrinol Metab 302:E103-7. 2012..008) but not 2% oxygen. We conclude that the absence of Pon3 in mice resulted in increased rates of early fetal and neonatal death. Knockdown of PON3 in human cells reduced cell proliferation and total antioxidant capacity...
- Developmental Expression and Glucocorticoid Control of the Leptin Receptor in Fetal Ovine LungMiles J De Blasio
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, United Kingdom
PLoS ONE 10:e0136115. 2015..Localisation of Ob-Rb in the fetal ovine lungs, including alveolar type II pneumocytes, suggests a role for leptin signalling in the control of lung growth and maturation before birth. ..