J R Jenkins
Affiliation: University of Liverpool
- Inhibition of Hsp90 acts synergistically with topoisomerase II poisons to increase the apoptotic killing of cells due to an increase in topoisomerase II mediated DNA damageCatherine R Barker
The Henry Wellcome Laboratory of Molecular and Cellular Gastroenterology, Division of Gastroenterology, School of Clinical Sciences, University of Liverpool, Crown Street, Liverpool L69 3BX, UK
Nucleic Acids Res 34:1148-57. 2006....
- A proteomic approach to identifying new drug targets (potentiating topoisomerase II poisons)J R Jenkins
School of Clinical Sciences, Division of Gastroenterology, University of Liverpool, Henry Wellcome Laboratory, Crown Street, Liverpool L69 3BX, UK
Br J Radiol 81:S69-77. 2008..The aim is to identify proteins, that by the nature of their interaction with topoisomerase II, represent putative drug targets...
- Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing miceC Bing
Obesity Biology Unit, Division of Metabolic and Cellular Medicine, School of Clinical Sciences, University of Liverpool, Liverpool L69 3GA, UK
Br J Cancer 95:1028-37. 2006..These results suggest that the tumour-induced impairment in the formation and lipid storing capacity of adipose tissue occurs in mice with cancer cachexia...