Sarosh R Irani

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
    Arq Neuropsiquiatr 70:300-4. 2012
  2. doi request reprint Morvan syndrome: clinical and serological observations in 29 cases
    Sarosh R Irani
    Neurosciences Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Neurol 72:241-55. 2012
  3. doi request reprint Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype
    Sarosh R Irani
    1 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Brain 136:3151-62. 2013
  4. pmc Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia
    Sarosh R Irani
    Neurosciences Group, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Brain 133:2734-48. 2010
  5. doi request reprint Autoimmune epilepsies
    Sarosh R Irani
    Department of Clinical Neurosciences Clinical Neurology, Oxford University, Oxford, UK
    Curr Opin Neurol 24:146-53. 2011
  6. doi request reprint Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis
    Sarosh R Irani
    Department of Clinical Neurology, Oxford University, Oxford, UK
    Ann Neurol 69:892-900. 2011
  7. doi request reprint Autoantibodies associated with diseases of the CNS: new developments and future challenges
    Angela Vincent
    Neuroimmunology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Lancet Neurol 10:759-72. 2011
  8. doi request reprint NMDA receptor antibody encephalitis
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Oxford OX39DS, UK
    Curr Neurol Neurosci Rep 11:298-304. 2011
  9. doi request reprint Potentially pathogenic autoantibodies associated with epilepsy and encephalitis in children and adults
    Angela Vincent
    Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, United Kingdom
    Epilepsia 52:8-11. 2011
  10. doi request reprint The growing recognition of immunotherapy-responsive seizure disorders with autoantibodies to specific neuronal proteins
    Angela Vincent
    Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
    Curr Opin Neurol 23:144-50. 2010

Detail Information

Publications16

  1. ncbi request reprint The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
    Arq Neuropsiquiatr 70:300-4. 2012
    ..In the present article, we have summarised recent developments in the clinical and laboratory findings within this rapidly expanding field...
  2. doi request reprint Morvan syndrome: clinical and serological observations in 29 cases
    Sarosh R Irani
    Neurosciences Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom
    Ann Neurol 72:241-55. 2012
    ....
  3. doi request reprint Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype
    Sarosh R Irani
    1 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Brain 136:3151-62. 2013
    ..Immunotherapy is associated with excellent control of the frequently anti-epileptic drug refractory seizures, hastens time to recovery, and may prevent the subsequent development of cognitive impairment observed in this study. ..
  4. pmc Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia
    Sarosh R Irani
    Neurosciences Group, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Brain 133:2734-48. 2010
    ....
  5. doi request reprint Autoimmune epilepsies
    Sarosh R Irani
    Department of Clinical Neurosciences Clinical Neurology, Oxford University, Oxford, UK
    Curr Opin Neurol 24:146-53. 2011
    ..To review the recent literature describing the detection and clinical importance of serum antibodies in patients with various epilepsies and other seizure-related disorders...
  6. doi request reprint Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis
    Sarosh R Irani
    Department of Clinical Neurology, Oxford University, Oxford, UK
    Ann Neurol 69:892-900. 2011
    ..To describe a distinctive seizure semiology that closely associates with voltage-gated potassium channel (VGKC)-complex/Lgi1 antibodies and commonly precedes the onset of limbic encephalitis (LE)...
  7. doi request reprint Autoantibodies associated with diseases of the CNS: new developments and future challenges
    Angela Vincent
    Neuroimmunology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Lancet Neurol 10:759-72. 2011
    ....
  8. doi request reprint NMDA receptor antibody encephalitis
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, Level 6, West Wing, John Radcliffe Hospital, Headley Way, Oxford OX39DS, UK
    Curr Neurol Neurosci Rep 11:298-304. 2011
    ....
  9. doi request reprint Potentially pathogenic autoantibodies associated with epilepsy and encephalitis in children and adults
    Angela Vincent
    Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, United Kingdom
    Epilepsia 52:8-11. 2011
    ..The conditions are often refractory to traditional antiepileptic drugs. Detection of these antibodies can help to identify forms of epilepsy that may respond to immunotherapies...
  10. doi request reprint The growing recognition of immunotherapy-responsive seizure disorders with autoantibodies to specific neuronal proteins
    Angela Vincent
    Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
    Curr Opin Neurol 23:144-50. 2010
    ..The concept of epilepsy and seizure disorders caused by autoantibodies to specific neuronal membrane proteins has developed significantly during the past few years...
  11. doi request reprint Caspr2 antibodies in patients with thymomas
    Angela Vincent
    Department of Clinical Neurology, John Radcliffe Hospital, Oxford, United Kingdom
    J Thorac Oncol 5:S277-80. 2010
    ..These antibodies are common in the subgroup of patients with thymic malignancies...
  12. ncbi request reprint Autoimmune encephalitis -- new awareness, challenging questions
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9TH, United Kingdom
    Discov Med 11:449-58. 2011
    ....
  13. pmc N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes
    Sarosh R Irani
    Department of Clinical Neurology, L6 West Wing, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK
    Brain 133:1655-67. 2010
    ..Four patients, who only had temporal lobe epilepsy without oligoclonal bands, may represent restriction to the first stage...
  14. doi request reprint The active intrathecal B-cell response in LGI1-antibody encephalitis
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK Electronic address
    Lancet 385:S46. 2015
    ..We aimed to investigate the migration and expansions of peripheral and central B cells to the production of LGI1-specific IgG...
  15. pmc Clinical and experimental studies of potentially pathogenic brain-directed autoantibodies: current knowledge and future directions
    James Varley
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, West Wing, Level 6, Oxford, OX3 9DU, UK
    J Neurol 262:1081-95. 2015
    ..Third, we discuss areas of controversy within the field, propose possible resolutions, and explore new directions for neuronal surface antibody-mediated diseases...
  16. pmc Cell-surface central nervous system autoantibodies: clinical relevance and emerging paradigms
    Sarosh R Irani
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom Multiple Sclerosis and Neuroinflammation Center, Department of Neurology, University of California, San Francisco, San Francisco, CA
    Ann Neurol 76:168-84. 2014
    ....