Genomes and Genes
Jerome H L Hui
Affiliation: University of Manchester
- Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genesJerome H L Hui
Department of Zoology, University of Oxford, Oxford, UK
BMC Biol 7:43. 2009..Conventional protostome models (Drosophila melanogaster and Caenorhabditis elegans) are secondarily derived with respect to ParaHox genes, suffering gene loss and cluster break-up...
- Extensive chordate and annelid macrosynteny reveals ancestral homeobox gene organizationJerome H L Hui
Department of Zoology, University of Oxford, Oxford, United Kingdom
Mol Biol Evol 29:157-65. 2012..dumerilii and chordates. This implies a very low rate of interchromosomal genome rearrangement in the lineages leading to P. dumerilii and the chordate ancestor since the time of the PDA...
- MicroRNA evolution by arm switchingSam Griffiths-Jones
Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK
EMBO Rep 12:172-7. 2011..Arm switching is likely to be general, and provides a fundamental mechanism to evolve the function of a miRNA locus and target gene network...
- A Burst of miRNA Innovation in the Early Evolution of Butterflies and MothsShan Quah
Department of Zoology, University of Oxford
Mol Biol Evol 32:1161-74. 2015..We propose a model by which miR-2768 modulates expression of ci in the segmentation pathway and in patterning of lepidopteran wing primordia. ..
- Do cnidarians have a ParaHox cluster? Analysis of synteny around a Nematostella homeobox gene clusterJerome H L Hui
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Evol Dev 10:725-30. 2008..This proves that the duplication that gave rise to the Hox and ParaHox regions of bilaterians occurred before the origin of cnidarians, and the cnidarian N. vectensis has bona fide Hox and ParaHox loci...
- The Lophotrochozoan TGF-β signalling cassette - diversification and conservation in a key signalling pathwayNathan J Kenny
Evolution and Development Research Group, Department of Zoology, University of Oxford, UK
Int J Dev Biol 58:533-49. 2014..Diversification within the activin-like complement, as well as potential wide loss of regulatory steps in some Phyla, hint at specific evolutionary implications for aspects of this cascade's functionality in this Superphylum. ..
- How are comparative genomics and the study of microRNAs changing our views on arthropod endocrinology and adaptations to the environment?Nathan J Kenny
Department of Zoology, University of Oxford, South Parks Road, OX1 3PS, UK
Gen Comp Endocrinol 188:16-22. 2013....