Daniel Hebenstreit

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc EpiChIP: gene-by-gene quantification of epigenetic modification levels
    Daniel Hebenstreit
    MRC Laboratory of Molecular Biology, Hills Rd, CB2 0QH Cambridge, UK
    Nucleic Acids Res 39:e27. 2011
  2. doi Analysis and simulation of gene expression profiles in pure and mixed cell populations
    Daniel Hebenstreit
    MRC Laboratory of Molecular Biology, Hills Rd, Cambridge CB2 0QH, UK
    Phys Biol 8:035013. 2011
  3. pmc RNA sequencing reveals two major classes of gene expression levels in metazoan cells
    Daniel Hebenstreit
    Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK
    Mol Syst Biol 7:497. 2011
  4. pmc The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding
    Xin Xie
    MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
    PLoS Genet 11:e1005251. 2015
  5. doi Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells
    Daniel Hebenstreit
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Curr Opin Cell Biol 24:350-8. 2012

Collaborators

Detail Information

Publications5

  1. pmc EpiChIP: gene-by-gene quantification of epigenetic modification levels
    Daniel Hebenstreit
    MRC Laboratory of Molecular Biology, Hills Rd, CB2 0QH Cambridge, UK
    Nucleic Acids Res 39:e27. 2011
    ..We have developed a software package called EpiChIP that carries out this type of analysis, including integration with and visualization of gene expression data...
  2. doi Analysis and simulation of gene expression profiles in pure and mixed cell populations
    Daniel Hebenstreit
    MRC Laboratory of Molecular Biology, Hills Rd, Cambridge CB2 0QH, UK
    Phys Biol 8:035013. 2011
    ..This will be important for the interpretation of next-generation sequencing data such as transcriptomics by mRNA-sequencing and ChIP-sequencing of epigenetic marks...
  3. pmc RNA sequencing reveals two major classes of gene expression levels in metazoan cells
    Daniel Hebenstreit
    Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK
    Mol Syst Biol 7:497. 2011
    ..These observations are confirmed in many other microarray and RNA-seq data sets of metazoan cell types...
  4. pmc The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding
    Xin Xie
    MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
    PLoS Genet 11:e1005251. 2015
    ..We show that, in one such mechanism, Foxp3 recruits class I histone deacetylases to the promoters of target genes, counteracting activation-induced histone acetylation and thereby suppressing their expression. ..
  5. doi Duel of the fates: the role of transcriptional circuits and noise in CD4+ cells
    Daniel Hebenstreit
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Curr Opin Cell Biol 24:350-8. 2012
    ..These processes and their interplay will also govern gene expression patterns in the different CD4+ cell types, and the determination of their cellular fates...