P R Heath

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. pmc The battle of the sexes starts in the oviduct: modulation of oviductal transcriptome by X and Y-bearing spermatozoa
    Carmen Almiñana
    Academic Unit of Reproductive and Developmental Medicine, Department of Human Metabolism, The University of Sheffield, Level 4, The Jessop Wing, Tree Root Walk, Sheffield S10 2SF, UK
    BMC Genomics 15:293. 2014
  2. pmc Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis
    Alice Brockington
    Academic Neurology Unit, University of Sheffield, E Floor, Medical School, Beech Hill Road, Sheffield S10 2RX, UK
    BMC Genomics 11:203. 2010
  3. ncbi request reprint Quantitative assessment of AMPA receptor mRNA in human spinal motor neurons isolated by laser capture microdissection
    P R Heath
    Academic Unit Neurology, Division of Genomic Medicine, Medical School, University of Sheffield, UK
    Neuroreport 13:1753-7. 2002
  4. doi request reprint Expression microdissection isolation of enriched cell populations from archival brain tissue
    C Appleby-Mallinder
    Sheffield Institute for Translational Neuroscience, University of Sheffield, UK
    J Neurosci Methods 268:125-30. 2016
  5. doi request reprint Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain
    C Garwood
    Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, UK
    Neuropathol Appl Neurobiol 39:788-99. 2013

Collaborators

  • S B Wharton
  • P J Shaw
  • Paul G Ince
  • C Appleby-Mallinder
  • J E Simpson
  • Carmen Almiñana
  • C Garwood
  • Alice Brockington
  • M D Wyles
  • Ignacio Caballero
  • Saeedeh Maleki-Dizaji
  • Juan Maria Vazquez
  • Inmaculada Parrilla
  • William Vincent Holt
  • Maria Antonia Gil
  • Alireza Fazeli
  • Cristina Cuello
  • Emilio Arsenio Martinez
  • Jordi Roca
  • Jose Luis Vazquez
  • C Gelsthorpe
  • A Faizullabhoy
  • G Forster
  • L Baxter
  • C Brayne
  • F E Matthews
  • Diether Lambrechts
  • Peter Carmeliet
  • Paul Kasher
  • Hazel Holden
  • Filip Claes
  • Florian L P Bender
  • Michael Sendtner

Detail Information

Publications6

  1. pmc The battle of the sexes starts in the oviduct: modulation of oviductal transcriptome by X and Y-bearing spermatozoa
    Carmen Almiñana
    Academic Unit of Reproductive and Developmental Medicine, Department of Human Metabolism, The University of Sheffield, Level 4, The Jessop Wing, Tree Root Walk, Sheffield S10 2SF, UK
    BMC Genomics 15:293. 2014
    ..Here we investigated the alternative possibility, namely that the oviducts can recognise X- and Y- spermatozoa, and may thus be able to bias the offspring sex ratio...
  2. pmc Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis
    Alice Brockington
    Academic Neurology Unit, University of Sheffield, E Floor, Medical School, Beech Hill Road, Sheffield S10 2RX, UK
    BMC Genomics 11:203. 2010
    ..Investigating the molecular pathways to neurodegeneration in the VEGFdelta/delta mouse model of ALS may improve understanding of the mechanisms of motor neurone death in the human disease...
  3. ncbi request reprint Quantitative assessment of AMPA receptor mRNA in human spinal motor neurons isolated by laser capture microdissection
    P R Heath
    Academic Unit Neurology, Division of Genomic Medicine, Medical School, University of Sheffield, UK
    Neuroreport 13:1753-7. 2002
    ..Thus, it is likely that human spinal motor neurons express a proportion of Ca2+-permeable AMPA receptors which may contribute to the selective vulnerability of these cells in amyotrophic lateral sclerosis...
  4. doi request reprint Expression microdissection isolation of enriched cell populations from archival brain tissue
    C Appleby-Mallinder
    Sheffield Institute for Translational Neuroscience, University of Sheffield, UK
    J Neurosci Methods 268:125-30. 2016
    ..Expression microdissection (xMD) is a new technique that begins to address these pitfalls, such as operator dependence and contamination...
  5. doi request reprint Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain
    C Garwood
    Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, UK
    Neuropathol Appl Neurobiol 39:788-99. 2013
    ..In this study we sought to determine the expression of calpain-10 and calcium/calmodulin-dependent kinase alpha (CamKIIα) in relation to Alzheimer-type pathology in a population-based study...