Bruce Guthrie

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Practice postcode versus patient population: a comparison of data sources in England and Scotland
    Gary McLean
    General Practice and Primary Care, Division of Community Based Sciences, University of Glasgow, Glasgow, 1 Horselethill Road Glasgow, G12 9LX, UK
    Int J Health Geogr 7:37. 2008
  2. pmc Differences in the quality of primary medical care for CVD and diabetes across the NHS: evidence from the quality and outcomes framework
    Gary McLean
    General Practice and Primary Care, University of Glasgow, Glasgow, UK
    BMC Health Serv Res 7:74. 2007
  3. doi request reprint The burden of psychotropic drug prescribingin people with dementia: a populationdatabase study
    Bruce Guthrie
    Quality, Safety and Informatics Research Group, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    Age Ageing 39:637-42. 2010
  4. pmc Control, compare and communicate: designing control charts to summarise efficiently data from multiple quality indicators
    B Guthrie
    Department of Community Health Sciences, University of Dundee, Dundee DD2 4BF, UK
    Qual Saf Health Care 14:450-4. 2005
  5. pmc Personal continuity and access in UK general practice: a qualitative study of general practitioners' and patients' perceptions of when and how they matter
    Bruce Guthrie
    Tayside Centre for General Practice, University of Dundee, Dundee DD2 4BF, UK
    BMC Fam Pract 7:11. 2006
  6. pmc Workload and reward in the Quality and Outcomes Framework of the 2004 general practice contract
    Bruce Guthrie
    Tayside Centre for General Practice, University of Dundee
    Br J Gen Pract 56:836-41. 2006
  7. pmc Routine mortality monitoring for detecting mass murder in UK general practice: test of effectiveness using modelling
    Bruce Guthrie
    Tayside Centre for General Practice, Community Health Sciences, University of Dundee, Dundee, Scotland
    Br J Gen Pract 58:311-7. 2008
  8. pmc Tackling therapeutic inertia: role of treatment data in quality indicators
    Bruce Guthrie
    Community Health Sciences, University of Dundee, Dundee DD2 4BF
    BMJ 335:542-4. 2007
  9. pmc Study protocol of a mixed-methods evaluation of a cluster randomized trial to improve the safety of NSAID and antiplatelet prescribing: data-driven quality improvement in primary care
    Aileen Grant
    Quality, Safety and Informatics Research Group, Population Health Sciences, University of Dundee, Mackenzie Building, Dundee DD2 4BF, UK
    Trials 13:154. 2012
  10. doi request reprint Psychoactive prescribing for older people--what difference does 15 years make?
    Lloyd D Hughes
    General Surgery, NHS Tayside, Dundee, UK
    Int J Geriatr Psychiatry 31:49-57. 2016

Detail Information

Publications52

  1. pmc Practice postcode versus patient population: a comparison of data sources in England and Scotland
    Gary McLean
    General Practice and Primary Care, Division of Community Based Sciences, University of Glasgow, Glasgow, 1 Horselethill Road Glasgow, G12 9LX, UK
    Int J Health Geogr 7:37. 2008
    ..Here, we report on the impact of using data assigned to the practice population by comparing analyses using English and Scottish data...
  2. pmc Differences in the quality of primary medical care for CVD and diabetes across the NHS: evidence from the quality and outcomes framework
    Gary McLean
    General Practice and Primary Care, University of Glasgow, Glasgow, UK
    BMC Health Serv Res 7:74. 2007
    ....
  3. doi request reprint The burden of psychotropic drug prescribingin people with dementia: a populationdatabase study
    Bruce Guthrie
    Quality, Safety and Informatics Research Group, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    Age Ageing 39:637-42. 2010
    ..to compare psychotropic prescribing in older people with dementia and the general elderly population...
  4. pmc Control, compare and communicate: designing control charts to summarise efficiently data from multiple quality indicators
    B Guthrie
    Department of Community Health Sciences, University of Dundee, Dundee DD2 4BF, UK
    Qual Saf Health Care 14:450-4. 2005
    ....
  5. pmc Personal continuity and access in UK general practice: a qualitative study of general practitioners' and patients' perceptions of when and how they matter
    Bruce Guthrie
    Tayside Centre for General Practice, University of Dundee, Dundee DD2 4BF, UK
    BMC Fam Pract 7:11. 2006
    ..This study examined patient and general practitioner (GP) perceptions of the value of personal continuity and rapid access, and the relationship between them...
  6. pmc Workload and reward in the Quality and Outcomes Framework of the 2004 general practice contract
    Bruce Guthrie
    Tayside Centre for General Practice, University of Dundee
    Br J Gen Pract 56:836-41. 2006
    ..The Quality and Outcomes Framework (QOF) of the 2004 UK General Medical Services (GMS) contract links up to 20% of practice income to performance measured against 146 quality indicators...
  7. pmc Routine mortality monitoring for detecting mass murder in UK general practice: test of effectiveness using modelling
    Bruce Guthrie
    Tayside Centre for General Practice, Community Health Sciences, University of Dundee, Dundee, Scotland
    Br J Gen Pract 58:311-7. 2008
    ..The Shipman Inquiry recommended mortality rate monitoring if it could be 'shown to be workable' in detecting a future mass murderer in general practice...
  8. pmc Tackling therapeutic inertia: role of treatment data in quality indicators
    Bruce Guthrie
    Community Health Sciences, University of Dundee, Dundee DD2 4BF
    BMJ 335:542-4. 2007
  9. pmc Study protocol of a mixed-methods evaluation of a cluster randomized trial to improve the safety of NSAID and antiplatelet prescribing: data-driven quality improvement in primary care
    Aileen Grant
    Quality, Safety and Informatics Research Group, Population Health Sciences, University of Dundee, Mackenzie Building, Dundee DD2 4BF, UK
    Trials 13:154. 2012
    ..This paper presents the mixed-method process evaluation protocol of a cluster randomized trial, drawing on a framework designed by the authors...
  10. doi request reprint Psychoactive prescribing for older people--what difference does 15 years make?
    Lloyd D Hughes
    General Surgery, NHS Tayside, Dundee, UK
    Int J Geriatr Psychiatry 31:49-57. 2016
    ..The objective of the study was to review prescribing of psychoactive medications for older residents of the Tayside region of Scotland...
  11. doi request reprint Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
    Karen Barnett
    Quality, Safety and Informatics Research Group, Population Health Sciences Division, University of Dundee, Dundee, UK
    Lancet 380:37-43. 2012
    ..We examined the distribution of multimorbidity, and of comorbidity of physical and mental health disorders, in relation to age and socioeconomic deprivation...
  12. doi request reprint Continuity of care matters
    Bruce Guthrie
    Primary Care Medicine, University of Dundee, Tayside Centre for General Practice, Dundee DD2 4BF
    BMJ 337:a867. 2008
  13. doi request reprint Spatio-temporal elements of articulation work in the achievement of repeat prescribing safety in UK general practice
    Suzanne Grant
    Division of Population Health Sciences, University of Dundee, Scotland
    Sociol Health Illn 38:306-24. 2016
    ..g. protocols). While GPs held formal prescribing authority, this paper also examines the key role of receptionists in both the initiation and safe coordination of the repeat prescribing routine. ..
  14. pmc Respiratory effect of beta-blocker eye drops in asthma: population-based study and meta-analysis of clinical trials
    Daniel R Morales
    Quality, Safety and Informatics Group, Division of Population Health Sciences, School of Medicine, University of Dundee, UK
    Br J Clin Pharmacol 82:814-22. 2016
    ..To measure the prevalence of beta-blocker eye drop prescribing and respiratory effect of ocular beta-blocker administration in people with asthma...
  15. pmc Process evaluations for cluster-randomised trials of complex interventions: a proposed framework for design and reporting
    Aileen Grant
    Quality, Safety and Informatics Research Group, Population Health Sciences, Medical Research Institute, University of Dundee, Mackenzie Building, Dundee DD2 4BF, UK
    Trials 14:15. 2013
    ..This discrepancy led us to develop our own framework for designing process evaluations of cluster-randomised controlled trials...
  16. pmc A cluster randomised stepped wedge trial to evaluate the effectiveness of a multifaceted information technology-based intervention in reducing high-risk prescribing of non-steroidal anti-inflammatory drugs and antiplatelets in primary medical care: the DQ
    Tobias Dreischulte
    Tayside Medicines Unit, NHS Tayside, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    Implement Sci 7:24. 2012
    ....
  17. ncbi request reprint Do general practice characteristics influence uptake of an information technology (IT) innovation in primary care?
    Josie M M Evans
    Lecturer in Epidemiology, Division of Community Health Sciences, University of Dundee, Scotland
    Inform Prim Care 16:3-8. 2008
    ..We evaluated whether structural characteristics of a general practice were associated with variations in use of a web-based clinical information system underpinning a Managed Clinical Network in diabetes, between the years 2001 and 2003...
  18. ncbi request reprint Continuity in UK general practice: a multilevel model of patient, doctor and practice factors associated with patients seeing their usual doctor
    Bruce Guthrie
    Department of Community Health Sciences General Practice, MacKenzie Medical Centre, 20 West Richmond Street, Edinburgh EH8 9DX, Scotland, UK
    Fam Pract 19:496-9. 2002
    ..Personal continuity is a 'core value' for UK general practice, but often appears ignored by organizational change...
  19. pmc Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study
    Daniel R Morales
    Quality, Safety and Informatics Group, Division of Population Health Sciences, School of Medicine, University of Dundee, Mackenzie Building, Dundee, DD2 4BF, UK
    BMC Med 15:18. 2017
    ..The aim of this study was to measure the risk of asthma exacerbations with beta-blockers prescribed to a general population with asthma and CVD...
  20. pmc Fair access to medicine? Retrospective analysis of UK medical schools application data 2009-2012 using three measures of socioeconomic status
    Kathryn Steven
    School of Medicine, University of Dundee, Dundee, Scotland
    BMC Med Educ 16:11. 2016
    ..The aim of this study was to examine variation in socioeconomic status (SES) of applicants to study medicine and applicants with an accepted offer from a medical school, comparing the four UK countries and individual medical schools...
  21. pmc Bad apples or spoiled barrels? Multilevel modelling analysis of variation in high-risk prescribing in Scotland between general practitioners and between the practices they work in
    Bruce Guthrie
    Quality, Safety and Informatics Research Group, Population Health Sciences Division, Medical Research Institute, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee, UK
    BMJ Open 5:e008270. 2015
    ..The study aimed to examine the extent of variation in high-risk prescribing between individual prescribers and between the practices they work in...
  22. doi request reprint Health plan competition for Medicaid enrollees based on performance does not improve quality of care
    Bruce Guthrie
    School of Medicine, University of Dundee, Scotland
    Health Aff (Millwood) 29:1507-16. 2010
    ..Combined with some evidence of negative impact on other areas of care, the findings raise questions about the usefulness of this program in California Medicaid, and about similar programs in other states...
  23. pmc Data feedback and behavioural change intervention to improve primary care prescribing safety (EFIPPS): multicentre, three arm, cluster randomised controlled trial
    Bruce Guthrie
    Population Health Sciences Division, University of Dundee, Dundee DD2 4BF, UK
    BMJ 354:i4079. 2016
    ..To evaluate the effectiveness of feedback on safety of prescribing compared with moderately enhanced usual care...
  24. doi request reprint Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: Meta-analysis of controlled clinical trials
    Daniel R Morales
    Quality, Safety and Informatics Group, Medical Research Institute, University of Dundee, Dundee, United Kingdom Electronic address
    J Allergy Clin Immunol 134:40-5. 2014
    ..Selective NSAIDs that preferentially inhibit COX-2 might be safer...
  25. pmc Differential impact of two risk communications on antipsychotic prescribing to people with dementia in Scotland: segmented regression time series analysis 2001-2011
    Bruce Guthrie
    Primary Care Medicine, Population Health Sciences Division, Medical Research Institute, Dundee, Scotland, United Kingdom
    PLoS ONE 8:e68976. 2013
    ..Two significant UK risk communications about antipsychotic use in older people with dementia were issued in 2004 and 2009. These varied considerably in their content and dissemination, allowing examination of their differential impact...
  26. doi request reprint An observational study of psychotropic drug use and initiation in older patients resident in their own home or in care
    Colin McCowan
    Division of Population Health Sciences, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    Age Ageing 42:51-6. 2013
    ..to compare the prescription of psychotropic medications for patients living in care homes with that for patients living at home...
  27. doi request reprint Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity
    Lloyd D Hughes
    Medical School, University of Dundee, MSO Level 10, Ninewells Hospital, Dundee, UK
    Age Ageing 42:62-9. 2013
    ..This is despite the fact that multimorbidity is a common phenomenon...
  28. pmc Quality and safety of medication use in primary care: consensus validation of a new set of explicit medication assessment criteria and prioritisation of topics for improvement
    Tobias Dreischulte
    Tayside Medicines Unit, NHS Tayside, Mackenzie Building, Kirsty Semple Way, Dundee, Scotland, DD2 4BF, UK
    BMC Clin Pharmacol 12:5. 2012
    ....
  29. doi request reprint High risk prescribing in primary care patients particularly vulnerable to adverse drug events: cross sectional population database analysis in Scottish general practice
    Bruce Guthrie
    Quality, Safety and Informatics Research Group, Centre for Primary Care and Population Research, University of Dundee, Kirsty Semple Way, Dundee DD2 4BF, UK
    BMJ 342:d3514. 2011
    ..To examine the prevalence and patterns of high risk prescribing, defined as potentially inappropriate prescribing of drugs to primary care patients particularly vulnerable to adverse drug events...
  30. doi request reprint Time series analysis of the impact of an intervention in Tayside, Scotland to reduce primary care broad-spectrum antimicrobial use
    Virginia Hernandez-Santiago
    Division of Population Health Sciences, Medical Research Institute, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    J Antimicrob Chemother 70:2397-404. 2015
    ..Our aim was to assess the impact of this real-world intervention on antimicrobial prescribing rates...
  31. doi request reprint Combined use of nonsteroidal anti-inflammatory drugs with diuretics and/or renin-angiotensin system inhibitors in the community increases the risk of acute kidney injury
    Tobias Dreischulte
    1 Population Health Sciences Division, Medical Research Institute, University of Dundee, Dundee, UK 2 NHS Tayside Medicines Governance Unit, Dundee, UK
    Kidney Int 88:396-403. 2015
    ..Thus, the nephrotoxic potential of both dual and triple combinations of NSAIDs with renin-angiotensin system inhibitors and/or diuretics yields a higher incidence of AKI than previously thought. ..
  32. pmc Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines
    Siobhan Dumbreck
    University of Dundee, Mackenzie Building, Dundee DD2 4BF, UK
    BMJ 350:h949. 2015
    ..To identify the number of drug-disease and drug-drug interactions for exemplar index conditions within National Institute of Health and Care Excellence (NICE) clinical guidelines...
  33. doi request reprint Soft governance, restratification and the 2004 general medical services contract: the case of UK primary care organisations and general practice teams
    Suzanne Grant
    Division of Population Health Sciences, Medical Research Institute, University of Dundee, UK
    Sociol Health Illn 37:30-51. 2015
    ....
  34. doi request reprint Use of oral anticoagulants in atrial fibrillation is highly variable and only weakly associated with estimated stroke risk: cross-sectional population database study
    Tobias Dreischulte
    Tayside Medicines Governance Unit, NHS Tayside, Dundee, UK
    Eur J Gen Pract 20:181-9. 2014
    ..Current international guidelines promote the use of stroke risk stratification tools to inform decision making about oral anticoagulant (OAC) use in atrial fibrillation (AF)...
  35. pmc Developing a complex intervention to improve prescribing safety in primary care: mixed methods feasibility and optimisation pilot study
    Aileen M Grant
    Quality, Safety and Informatics Group, Population Health Sciences, Medical Research Institute, University of Dundee, Dundee, UK
    BMJ Open 4:e004153. 2014
    ..B) To explore the value of reviewing identified high-risk prescribing to clinicians.(C) To optimise the components of the DQIP intervention...
  36. pmc Physical and mental health comorbidity is common in people with multiple sclerosis: nationally representative cross-sectional population database analysis
    Robert J Simpson
    General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, Glasgow G12 9LX, Scotland, UK
    BMC Neurol 14:128. 2014
    ..Comorbidity in Multiple Sclerosis (MS) is associated with worse health and higher mortality. This study aims to describe clinician recorded comorbidities in people with MS...
  37. doi request reprint Long-acting β-agonist prescribing in people with asthma in primary care
    Daniel R Morales
    Population Health Sciences Division, Medical Research Institute, University of Dundee, Dundee, UK
    Thorax 68:192-4. 2013
    ..44; 95% CI 0.32 to 0.61) but not episodic monotherapy (OR 1.16; 95% CI 0.85 to 1.57). These findings support recent changes in UK asthma guidelines recommending LABAs in fixed-dose combination inhalers...
  38. pmc Insightful practice: a reliable measure for medical revalidation
    Douglas J Murphy
    Quality, Safety and Informatics Research Group, University of Dundee, Dundee, UK
    BMJ Qual Saf 21:649-56. 2012
    ..This study tested an innovative method in which general practitioners (GPs) were assessed on their reflection and response to a set of externally specified feedback...
  39. pmc Trends in primary care antidepressant prescribing 1995-2007: a longitudinal population database analysis
    Pauline Lockhart
    Quality, Safety and Informatics Research Group, University of Dundee, Scotland
    Br J Gen Pract 61:e565-72. 2011
    ..Antidepressant prescribing is increasing worldwide, prompting policy interventions and targets to halt the rise...
  40. pmc Impact of the GP contract on inequalities associated with influenza immunisation: a retrospective population-database analysis
    Michael Norbury
    Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
    Br J Gen Pract 61:e379-85. 2011
    ..Influenza immunisation is recommended for all people aged ≥65 years and younger people with particular chronic diseases. The Quality and Outcomes Framework (QOF) has provided new financial incentives for influenza immunisation since 2004...
  41. doi request reprint Physical and mental health comorbidities of epilepsy: Population-based cross-sectional analysis of 1.5 million people in Scotland
    Christopher J Weatherburn
    Quality, Safety and Informatics Research Group, Population Health Sciences Division, Ninewells Hospital and Medical School, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee DD2 4BF, UK
    Seizure 45:125-131. 2016
    ..To measure the prevalence of physical and mental health comorbidities in people with epilepsy in a large population cohort, and to examine the prevalence of depression accounting for other physical comorbidity...
  42. pmc The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995-2010
    Bruce Guthrie
    Population Health Sciences Division, Medical Research Institute, University of Dundee, Mackenzie Building, Kirsty Semple Way, Dundee, DD2 4BF, UK
    BMC Med 13:74. 2015
    ..This study aims to examine changes in rates of polypharmacy and potentially serious drug-drug interactions in a stable geographical population between 1995 and 2010...
  43. doi request reprint Temporal trends in anticholinergic medication prescription in older people: repeated cross-sectional analysis of population prescribing data
    Deepa Sumukadas
    Ageing and Health, Division of Cardiovascular and Diabetes Medicine, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK
    Age Ageing 43:515-21. 2014
    ..Many anticholinergics are recognised as potentially inappropriate and efforts to reduce prescription have been ongoing. We examined temporal trends of anticholinergic prescription and exposure in older people...
  44. doi request reprint Which people with Type 2 diabetes achieve good control of intermediate outcomes? Population database study in a UK region
    B Guthrie
    University of Dundee, Dundee, UK
    Diabet Med 26:1269-76. 2009
    ..To measure quality of vascular risk factor measurement and control in people with Type 2 diabetes after comprehensive pay-for-performance implementation and to examine variation by patient and practice characteristics...
  45. doi request reprint Biomedicine, holism and general medical practice: responses to the 2004 General Practitioner contract
    Kath Checkland
    National Primary Care Research and Development Centre, University of Manchester, Manchester
    Sociol Health Illn 30:788-803. 2008
    ..We discuss how this disconnection between rhetoric and reality can be maintained, and consider its implications for the future development of GPs' claims to a professional identity...
  46. pmc Differences in the quality of primary medical care services by remoteness from urban settlements
    Gary McLean
    Department of General Practice and Primary Care, Community Based Sciences, University of Glasgow, 1 Horselethill Road, Glasgow G12 9LX, UK
    Qual Saf Health Care 16:446-9. 2007
    ..To examine if the quality of primary medical care varies with remoteness from urban settlements...
  47. pmc Can mortality monitoring in general practice be made to work?
    Bruce Guthrie
    Br J Gen Pract 55:660-3. 2005
  48. ncbi request reprint Is success in postgraduate examinations associated with family practitioners' attitudes or patient perceptions of the quality of their consultations? A cross-sectional study of the MRCGP examination in Great Britain
    Brian McKinstry
    University of Edinburgh, UK
    Fam Pract 22:653-7. 2005
    ..It is not clear, however, if this process identifies quality markers that patients can perceive...
  49. pmc Quality measurement of care for people with type 2 diabetes in Tayside, Scotland: implications for the new UK general practice contract
    Bruce Guthrie
    Department of Community Health Sciences, General Practice, University of Edinburgh, 20 West Richmond Street, Edinburgh EH8 9DX
    Br J Gen Pract 53:709-13. 2003
    ..The new United Kingdom general practice contract proposes that up to a third of general practitioners' income will come from achieving quality targets...
  50. doi request reprint Measuring the quality of healthcare systems using composites
    Bruce Guthrie
    BMJ 337:a639. 2008
  51. ncbi request reprint Whither British general practice after the 2004 GMS contract? Stories and realities of change in four UK general practices
    Guro Huby
    School of Health in Social Science, University of Edinburgh, Edinburgh, UK
    J Health Organ Manag 22:63-78. 2008
    ..The purpose of this article is to provide answers to two questions: what has been the impact of nGMS on practice organisation and teamwork; and how do general practice staff perceive the impact?..
  52. pmc Designing and evaluating complex interventions to improve health care
    Neil C Campbell
    Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen AB25 2AY
    BMJ 334:455-9. 2007