Timothy D Griffiths

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. pmc fMRI evidence for a cortical hierarchy of pitch pattern processing
    Lauren Stewart
    Department of Psychology, Goldsmiths, University of London, London, United Kingdom
    PLoS ONE 3:e1470. 2008
  2. doi request reprint Sounds familiar?
    Timothy D Griffiths
    Newcastle University, Newcastle upon Tyne NE1 7RU, UK
    Neuron 66:475-6. 2010
  3. ncbi request reprint Sorting out sound
    Timothy D Griffiths
    Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
    Neuron 56:580-1. 2007
  4. doi request reprint Sensory systems: auditory action streams?
    Timothy D Griffiths
    Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, UK
    Curr Biol 18:R387-8. 2008
  5. pmc Direct recordings of pitch responses from human auditory cortex
    Timothy D Griffiths
    Institute of Neuroscience, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    Curr Biol 20:1128-32. 2010
  6. pmc Predictive coding and pitch processing in the auditory cortex
    Sukhbinder Kumar
    Newcastle University Medical School, UK
    J Cogn Neurosci 23:3084-94. 2011
  7. pmc Distinct critical cerebellar subregions for components of verbal working memory
    Freya E Cooper
    Institute of Neuroscience, Newcastle University, UK
    Neuropsychologia 50:189-97. 2012
  8. doi request reprint A dynamic system for the analysis of acoustic features and valence of aversive sounds in the human brain
    Sukhbinder Kumar
    Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    Adv Exp Med Biol 787:463-72. 2013
  9. pmc Auditory temporal-regularity processing correlates with language and literacy skill in early adulthood
    Manon Grube
    a Newcastle Auditory Group, Medical School, Newcastle University, Newcastle upon Tyne, UK
    Cogn Neurosci 4:225-30. 2013
  10. pmc Auditory sequence analysis and phonological skill
    Manon Grube
    Newcastle Auditory Group, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    Proc Biol Sci 279:4496-504. 2012

Detail Information

Publications55

  1. pmc fMRI evidence for a cortical hierarchy of pitch pattern processing
    Lauren Stewart
    Department of Psychology, Goldsmiths, University of London, London, United Kingdom
    PLoS ONE 3:e1470. 2008
    ....
  2. doi request reprint Sounds familiar?
    Timothy D Griffiths
    Newcastle University, Newcastle upon Tyne NE1 7RU, UK
    Neuron 66:475-6. 2010
    ..Work by Agus and colleagues in this issue of Neuron defines a human mechanism for the rapid learning of novel noises. The noises do not have a verbal label, and are stored accurately for weeks...
  3. ncbi request reprint Sorting out sound
    Timothy D Griffiths
    Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
    Neuron 56:580-1. 2007
    ....
  4. doi request reprint Sensory systems: auditory action streams?
    Timothy D Griffiths
    Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, UK
    Curr Biol 18:R387-8. 2008
    ..Two recent studies suggest the existence of a comparable mechanism in the auditory system...
  5. pmc Direct recordings of pitch responses from human auditory cortex
    Timothy D Griffiths
    Institute of Neuroscience, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    Curr Biol 20:1128-32. 2010
    ..The research suggests that two types of pitch-related activity occur in humans in early auditory cortex: time-locked neural correlates of stimulus regularity and an oscillatory response related to the pitch percept...
  6. pmc Predictive coding and pitch processing in the auditory cortex
    Sukhbinder Kumar
    Newcastle University Medical School, UK
    J Cogn Neurosci 23:3084-94. 2011
    ..The data show that representation of pitch requires an interaction between nonprimary and primary auditory cortex along HG that is consistent with the principle of predictive coding...
  7. pmc Distinct critical cerebellar subregions for components of verbal working memory
    Freya E Cooper
    Institute of Neuroscience, Newcastle University, UK
    Neuropsychologia 50:189-97. 2012
    ..The work confirms the involvement of the cerebellum in verbal working memory and defines specific subsystems for this within the cerebellum...
  8. doi request reprint A dynamic system for the analysis of acoustic features and valence of aversive sounds in the human brain
    Sukhbinder Kumar
    Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    Adv Exp Med Biol 787:463-72. 2013
    ..The results support interaction between the auditory cortex and amygdala where stimuli are first processed to a higher (object) level in the auditory cortex before assignment of valence in the amygdala...
  9. pmc Auditory temporal-regularity processing correlates with language and literacy skill in early adulthood
    Manon Grube
    a Newcastle Auditory Group, Medical School, Newcastle University, Newcastle upon Tyne, UK
    Cogn Neurosci 4:225-30. 2013
    ..The data implicate a specific role for the ability to process beat-based temporal regularities in phonological language and literacy skill. ..
  10. pmc Auditory sequence analysis and phonological skill
    Manon Grube
    Newcastle Auditory Group, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    Proc Biol Sci 279:4496-504. 2012
    ....
  11. ncbi request reprint Approaches to the cortical analysis of auditory objects
    Timothy D Griffiths
    Auditory Group, Medical School, Framlington Place, University of Newcastle, Newcastle upon Tyne, UK
    Hear Res 229:46-53. 2007
    ..The subjects have lesions of the normal network described above with normal perception of pitch strength but abnormal perception of the analysis of spectral envelope change...
  12. pmc Features versus feelings: dissociable representations of the acoustic features and valence of aversive sounds
    Sukhbinder Kumar
    Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom
    J Neurosci 32:14184-92. 2012
    ....
  13. doi request reprint Mapping unpleasantness of sounds to their auditory representation
    Sukhbinder Kumar
    Auditory Group, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, United Kingdom
    J Acoust Soc Am 124:3810-7. 2008
    ..It was observed that the existence region corresponded to spectral frequencies between 2500 and 5500 Hz, and temporal modulations in the range 1-16 Hz...
  14. pmc Neural signatures of perceptual inference
    William Sedley
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom
    elife 5:e11476. 2016
    ..These results confirm oscillatory codes for critical aspects of generative models of perception. ..
  15. doi request reprint Temporal predictions based on a gradual change in tempo
    Thomas E Cope
    Auditory Group, Institute of Neuroscience, Newcastle University, Tyne and Wear NE1 7RU, United Kingdom
    J Acoust Soc Am 131:4013-22. 2012
    ..The data support "multiple-look" and entrainment models of tempo sensitivity and suggest that temporal prediction is based less on the tempo contour of a whole sequence than on the duration of the preceding interval...
  16. pmc Dissociation of duration-based and beat-based auditory timing in cerebellar degeneration
    Manon Grube
    Newcastle Auditory Group, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom
    Proc Natl Acad Sci U S A 107:11597-601. 2010
    ..The findings support the existence of a stopwatch-like cerebellar timing mechanism for absolute intervals that is distinct from mechanisms for entrainment with a regular beat...
  17. pmc Orthogonal representation of sound dimensions in the primate midbrain
    Simon Baumann
    Institute of Neuroscience, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
    Nat Neurosci 14:423-5. 2011
    ..These representations are organized as a map with two approximately perpendicular axes: one representing increasing temporal rate and the other increasing spectral frequency...
  18. pmc Intracranial Mapping of a Cortical Tinnitus System using Residual Inhibition
    William Sedley
    Human Brain Research Laboratory, Department of Neurosurgery, The University of Iowa, Iowa City, IA 52242, USA Auditory Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, Tyne and Wear NE2 4HH, UK Electronic address
    Curr Biol 25:1208-14. 2015
    ....
  19. pmc Gamma band pitch responses in human auditory cortex measured with magnetoencephalography
    William Sedley
    Auditory Group, Institute of Neuroscience, Newcastle University Medical School, Newcastle upon Tyne, Tyne and Wear, NE2 4HH UK
    Neuroimage 59:1904-11. 2012
    ..These findings provide further support that auditory high gamma oscillations occur in association with RIN pitch stimuli, and validate the use of MEG to assess neural correlates of normal and abnormal pitch perception...
  20. pmc A brain basis for musical hallucinations
    Sukhbinder Kumar
    Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne, UK Wellcome Trust Centre for Neuroimaging, London, UK Electronic address
    Cortex 52:86-97. 2014
    ..The data indicate that these areas form a crucial network in the generation of MH, and are consistent with a model in which MH are generated by persistent reciprocal communication in a predictive coding hierarchy. ..
  21. ncbi request reprint Neural bases of musical hallucinations
    Sukhbinder Kumar
    Auditory Group, Institute of Neuroscience, Newcastle University Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom
    J Neurol Neurosurg Psychiatry 85:e3. 2014
    ..We then combine our results with the computational theories of brain function to propose a model of how the brain generates and maintain MH...
  22. ncbi request reprint Music and the brain: disorders of musical listening
    Lauren Stewart
    Auditory Group, Newcastle University, Newcastle upon Tyne, London, UK
    Brain 129:2533-53. 2006
    ..Both the bases for normal musical listening and the clinical assessment of disorders now have a solid grounding in systems neuroscience...
  23. doi request reprint Metricality-enhanced temporal encoding and the subjective perception of rhythmic sequences
    Manon Grube
    Newcastle Auditory Group, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    Cortex 45:72-9. 2009
    ..The data support an increase in the precision of temporal pattern encoding for sequences with a higher-order metrical time framework...
  24. pmc An Integrative Tinnitus Model Based on Sensory Precision
    William Sedley
    Institute of Neuroscience, Newcastle University Medical School, Newcastle upon Tyne, UK Electronic address
    Trends Neurosci 39:799-812. 2016
    ..e., postsynaptic gain) rises sufficiently then tinnitus is perceived. Perpetuation arises through focused attention, which further increases the precision of the precursor, and resetting of the default prediction to expect tinnitus...
  25. pmc Individually customisable non-invasive head immobilisation system for non-human primates with an option for voluntary engagement
    Heather Slater
    Institute of Neuroscience, Henry Wellcome Building, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom Centre for Behaviour and Evolution, Henry Wellcome Building, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom
    J Neurosci Methods 269:46-60. 2016
    ..A number of Non-invasive Head Immobilisation Systems (NHIS) for monkeys are available, but the need remains for a feasible integrated system combining a broad range of essential features...
  26. pmc Auditory sequence processing reveals evolutionarily conserved regions of frontal cortex in macaques and humans
    Benjamin Wilson
    Institute of Neuroscience, Henry Wellcome Building, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
    Nat Commun 6:8901. 2015
    ..This study raises the possibility that certain ventral frontal neural systems, which play a significant role in language function in modern humans, originally evolved to support domain-general abilities involved in sequence processing. ..
  27. ncbi request reprint Mapping pitch representation in neural ensembles with fMRI
    Timothy D Griffiths
    Institute of Neuroscience, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom
    J Neurosci 32:13343-7. 2012
    ..The BOLD data provide support for the pitch-center concept, with ongoing debate about its location...
  28. pmc Characterisation of the BOLD response time course at different levels of the auditory pathway in non-human primates
    Simon Baumann
    Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
    Neuroimage 50:1099-108. 2010
    ..Furthermore, the data will aid optimal design of future auditory fMRI studies in non-human primates...
  29. ncbi request reprint Rhythm deficits in 'tone deafness'
    Jessica M Foxton
    Auditory Group, University of Newcastle upon Tyne, Framlington Place, Newcastle NE2 4HH, UK
    Brain Cogn 62:24-9. 2006
    ..These results suggest that the rhythm deficits in congenital amusia result from the pitch-variations in music...
  30. pmc A Brain System for Auditory Working Memory
    Sukhbinder Kumar
    Auditory Group, Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom, Wellcome Trust Centre for Neuroimaging, London WC1N 3BG, United Kingdom
    J Neurosci 36:4492-505. 2016
    ..The data support a system for auditory working memory based on the maintenance of sound-specific representations in auditory cortex by projections from higher-order areas, including the hippocampus and frontal cortex...
  31. pmc Subthalamic deep brain stimulation in Parkinson׳s disease has no significant effect on perceptual timing in the hundreds of milliseconds range
    Thomas E Cope
    Auditory Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom Electronic address
    Neuropsychologia 57:29-37. 2014
    ..Further, they suggest that the connections between STN and the subtantia nigra and globus pallidus are unlikely to be critical to beat-based perceptual timing. ..
  32. pmc Exploring the role of auditory analysis in atypical compared to typical language development
    Manon Grube
    Institute of Neuroscience, Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK Electronic address
    Hear Res 308:129-40. 2014
    ..These might include types of musical training to augment language skills via their common bases in sound sequence analysis...
  33. ncbi request reprint Training improves acoustic pattern perception
    Jessica M Foxton
    Auditory Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom
    Curr Biol 14:322-5. 2004
    ..Further studies are required to determine whether pitch-contour training is effective in improving speech and melody perception...
  34. ncbi request reprint Characterization of deficits in pitch perception underlying 'tone deafness'
    Jessica M Foxton
    Auditory Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, UK
    Brain 127:801-10. 2004
    ..In contrast, no abnormalities were identified in the perceptual organization of pitch. The pitch deficits identified are able to account for the music perception difficulties in this disorder, and implicate deficient cortical processing...
  35. pmc The contribution of the cerebellum to cognition in Spinocerebellar Ataxia Type 6
    Freya E Cooper
    Institute of Neuroscience, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne, UK
    Behav Neurol 23:3-15. 2010
    ....
  36. ncbi request reprint Absence of auditory 'global interference' in autism
    Jessica M Foxton
    School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Brain 126:2703-9. 2003
    ..This was attributed to the absence of interference from an auditory coherent whole. The results are consistent with the presence of abnormal interactions between local and global auditory perception in ASD...
  37. pmc Representations of specific acoustic patterns in the auditory cortex and hippocampus
    Sukhbinder Kumar
    Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Proc Biol Sci 281:20141000. 2014
    ..Our results demonstrate that these structures are involved in the neural representation of specific acoustic patterns after they have been learnt. ..
  38. ncbi request reprint Misophonia: a disorder of emotion processing of sounds
    Sukhbinder Kumar
    Auditory Group Institute of Neuroscience, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom
    J Neurol Neurosurg Psychiatry 85:e3. 2014
    ..The objective of the current work was to check the consistency of profile of symptoms and trigger sounds in a population of subjects with misophonia...
  39. pmc A unified framework for the organization of the primate auditory cortex
    Simon Baumann
    Medical Faculty, Institute of Neuroscience, Newcastle University Newcastle upon Tyne, UK
    Front Syst Neurosci 7:11. 2013
    ..This unified framework allows a more robust and detailed comparison of auditory cortex organization across primate species including humans...
  40. pmc Core auditory processing deficits in primary progressive aphasia
    Manon Grube
    1 Institute of Neuroscience, Medical School, Newcastle University, Newcastle upon Tyne, UK 2 Machine Learning Group, Department of Computer Science, Berlin Institute of Technology, Berlin, Germany
    Brain 139:1817-29. 2016
    ..Parsimoniously we propose that auditory timing pathways are altered, which are used in common for processing acoustic sequence structure in both speech output and acoustic input. ..
  41. pmc Neural Correlates of Auditory Figure-Ground Segregation Based on Temporal Coherence
    Sundeep Teki
    Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, UK Auditory Cognition Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK Current address Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK
    Cereb Cortex 26:3669-80. 2016
    ....
  42. ncbi request reprint Reading skills are related to global, but not local, acoustic pattern perception
    Jessica M Foxton
    Auditory Group, School of Neurology, Neurobiology and Psychiatry, University of Newcastle upon Tyne, Framlington Place, Newcastle NE2 4HH, UK
    Nat Neurosci 6:343-4. 2003
  43. pmc Transcranial magnetic theta-burst stimulation of the human cerebellum distinguishes absolute, duration-based from relative, beat-based perception of subsecond time intervals
    Manon Grube
    Newcastle Auditory Group, Institute of Neuroscience, Medical School, Newcastle University, Framlington Place Newcastle upon Tyne, UK
    Front Psychol 1:171. 2010
    ....
  44. ncbi request reprint What is an auditory object?
    Timothy D Griffiths
    Auditory Group, University of Newcastle Medical School, Newcastle upon Tyne NE2 4HH, UK
    Nat Rev Neurosci 5:887-92. 2004
    ..The concept of an auditory object challenges our understanding of object perception. Here, we offer a critical perspective on the concept and its basis in the brain...
  45. ncbi request reprint Central auditory processing disorders
    Timothy D Griffiths
    Department of Neurology, Newcastle University Medical School, Newcastle upon Tyne, UK
    Curr Opin Neurol 15:31-3. 2002
    ..Recent work has investigated sound processing by the unconscious brain; such investigations may provide a 'window' into residual brain function and prognosis...
  46. ncbi request reprint The planum temporale as a computational hub
    Timothy D Griffiths
    Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    Trends Neurosci 25:348-53. 2002
    ..We review the evidence for the model and specific predictions that follow from it...
  47. ncbi request reprint Morphometry of the amusic brain: a two-site study
    Krista L Hyde
    Department of Psychology, University of Montreal, Montreal, Quebec, Canada
    Brain 129:2562-70. 2006
    ..Moreover, the data point to the integrity of white matter tracts in right frontal brain areas as being key in acquiring normal musical competence...
  48. pmc An information theoretic characterisation of auditory encoding
    Tobias Overath
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom
    PLoS Biol 5:e288. 2007
    ..The results establish PT as an efficient neural engine that demands less computational resource to encode redundant signals than those with high information content...
  49. ncbi request reprint Musically tone-deaf individuals have difficulty discriminating intonation contours extracted from speech
    Aniruddh D Patel
    The Neurosciences Institute, San Diego, CA, USA
    Brain Cogn 59:310-3. 2005
    ..Thus it appears that the dissociation between spoken and musical pitch perception in tone-deaf individuals is due to a deficit at a higher level than simple pitch-change detection...
  50. ncbi request reprint Perception of sound-source motion by the human brain
    Jason D Warren
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neuron 34:139-48. 2002
    ..The results support the existence of a posteriorly directed temporo-parietal pathway for obligatory perceptual processing of sound-source motion...
  51. ncbi request reprint Cortical processing of complex sound: a way forward?
    Timothy D Griffiths
    Department of Psychology, University College London, London WC1H 0AP, UK
    Trends Neurosci 27:181-5. 2004
    ..There is a crucial need for better understanding of the anatomy of the auditory cortex in different species and for comparative studies that will underpin both approaches...
  52. ncbi request reprint The processing of temporal pitch and melody information in auditory cortex
    Roy D Patterson
    Centre for the Neural Basis of Hearing, Physiology Department, University of Cambridge, Downing Street, Cambridge, United Kingdom
    Neuron 36:767-76. 2002
    ..The results support the view that there is hierarchy of pitch processing in which the center of activity moves anterolaterally away from primary auditory cortex as the processing of melodic sounds proceeds...
  53. ncbi request reprint Cortical thickness in congenital amusia: when less is better than more
    Krista L Hyde
    Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4
    J Neurosci 27:13028-32. 2007
    ..These cortical thickness differences suggest the presence of cortical malformations in the amusic brain, such as abnormal neuronal migration, that may have compromised the normal development of a right frontotemporal pathway...
  54. ncbi request reprint A neural basis for the perception of voices in external auditory space
    Michael D Hunter
    Sheffield Cognition and Neuroimaging Laboratory, Academic Department of Psychiatry, University of Sheffield, Sheffield, UK
    Brain 126:161-9. 2003
    ..Based on this, we suggest a model for the false perception of externally located auditory verbal hallucinations...
  55. ncbi request reprint Analyzing pitch chroma and pitch height in the human brain
    Jason D Warren
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, Queen Square, London, United Kingdom
    Ann N Y Acad Sci 999:212-4. 2003
    ....