Jean Golding

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Prenatal mercury exposure and offspring behaviour in childhood and adolescence
    Jean Golding
    Centre for Child and Adolescent Health, University of Bristol, UK Electronic address
    Neurotoxicology 57:87-94. 2016
  2. pmc Associations between prenatal mercury exposure and early child development in the ALSPAC study
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK Electronic address
    Neurotoxicology 53:215-22. 2016
  3. pmc Predictors of positive and negative parenting behaviours: evidence from the ALSPAC cohort
    Rachel M Thomson
    Centre for Rural Health, The Centre for Health Science, University of Aberdeen, Old Perth Road, Inverness IV2 3JH, Scotland
    BMC Pediatr 14:247. 2014
  4. pmc A review of environmental contributions to childhood motor skills
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    J Child Neurol 29:1531-47. 2014
  5. pmc Parental, prenatal, and neonatal associations with ball skills at age 8 using an exposome approach
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    J Child Neurol 29:1390-8. 2014
  6. pmc Parent-infant vocalisations at 12 months predict psychopathology at 7 years
    C S Allely
    Institute of Health and Wellbeing, University of Glasgow, RHSC Yorkhill, Glasgow, Scotland, UK
    Res Dev Disabil 34:985-93. 2013
  7. pmc Prediction of 7-year psychopathology from mother-infant joint attention behaviours: a nested case-control study
    Clare S Allely
    Centre for Rural Health, University of Aberdeen, The Centre for Health Science, Old Perth Road, Inverness IV2 3JH, Scotland
    BMC Pediatr 13:147. 2013
  8. pmc Association between parent-infant interactions in infancy and disruptive behaviour disorders at age seven: a nested, case-control ALSPAC study
    Christine Puckering
    Robertson Centre for Biostatistics, University of Glasgow, Boyd Orr Building, Glasgow, Scotland G12 8QQ, UK
    BMC Pediatr 14:223. 2014
  9. pmc Socioeconomic position and overweight among adolescents: data from birth cohort studies in Brazil and the UK
    Alicia Matijasevich
    Post Graduate Programme in Epidemiology, Federal University of Pelotas, RS, Brazil
    BMC Public Health 9:105. 2009
  10. doi request reprint The overall placing and management structure of a longitudinal birth cohort
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:23-30. 2009

Collaborators

Detail Information

Publications115 found, 100 shown here

  1. pmc Prenatal mercury exposure and offspring behaviour in childhood and adolescence
    Jean Golding
    Centre for Child and Adolescent Health, University of Bristol, UK Electronic address
    Neurotoxicology 57:87-94. 2016
    ..Further information is needed to inform debate and clarify policy recommendations...
  2. pmc Associations between prenatal mercury exposure and early child development in the ALSPAC study
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK Electronic address
    Neurotoxicology 53:215-22. 2016
    ..However there is uncertainty as to whether lower levels of the metal have adverse effects on the development of the infant and whether components of fish consumption and/or the selenium status of the woman is protective...
  3. pmc Predictors of positive and negative parenting behaviours: evidence from the ALSPAC cohort
    Rachel M Thomson
    Centre for Rural Health, The Centre for Health Science, University of Aberdeen, Old Perth Road, Inverness IV2 3JH, Scotland
    BMC Pediatr 14:247. 2014
    ..This study used a single assessment of parenting behaviours and started with a wide range of potential pre- and post-natal variables; such an approach might be used to identify families who might benefit from parenting interventions...
  4. pmc A review of environmental contributions to childhood motor skills
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    J Child Neurol 29:1531-47. 2014
    ..The child appearing to be most at risk was born of low birth weight (but not due to preterm delivery) or with neonatal problems. ..
  5. pmc Parental, prenatal, and neonatal associations with ball skills at age 8 using an exposome approach
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    J Child Neurol 29:1390-8. 2014
    ..Future studies of this cohort will be used to determine whether the mechanism is manifest through differing parenting skills, or a biological mechanism reflecting epigenetic effects. ..
  6. pmc Parent-infant vocalisations at 12 months predict psychopathology at 7 years
    C S Allely
    Institute of Health and Wellbeing, University of Glasgow, RHSC Yorkhill, Glasgow, Scotland, UK
    Res Dev Disabil 34:985-93. 2013
    ..In sum, altered vocalisation frequency in mother-infant interactions at one year is a potential risk marker for later diagnosis of a range of child psychopathologies...
  7. pmc Prediction of 7-year psychopathology from mother-infant joint attention behaviours: a nested case-control study
    Clare S Allely
    Centre for Rural Health, University of Aberdeen, The Centre for Health Science, Old Perth Road, Inverness IV2 3JH, Scotland
    BMC Pediatr 13:147. 2013
    ..To investigate whether later diagnosis of psychiatric disorder can be predicted from analysis of mother-infant joint attention (JA) behaviours in social-communicative interaction at 12 months...
  8. pmc Association between parent-infant interactions in infancy and disruptive behaviour disorders at age seven: a nested, case-control ALSPAC study
    Christine Puckering
    Robertson Centre for Biostatistics, University of Glasgow, Boyd Orr Building, Glasgow, Scotland G12 8QQ, UK
    BMC Pediatr 14:223. 2014
    ..Patterns of parent-child interaction may predict oppositional/conduct disorders but large community-based prospective studies are needed to evaluate this possibility...
  9. pmc Socioeconomic position and overweight among adolescents: data from birth cohort studies in Brazil and the UK
    Alicia Matijasevich
    Post Graduate Programme in Epidemiology, Federal University of Pelotas, RS, Brazil
    BMC Public Health 9:105. 2009
    ..The patterns of overweight/obesity differ by age, sex, rural or urban residence and socioeconomic position (SEP) and vary between and within countries...
  10. doi request reprint The overall placing and management structure of a longitudinal birth cohort
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:23-30. 2009
    ..In this paper we discuss the ways in which other birth cohort studies have made these choices and outline the advantages and disadvantages of different scenarios...
  11. doi request reprint Who should be studied and when in a longitudinal birth cohort?
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:15-22. 2009
    ..Here we discuss the optimal time to start such a study, and criteria for inclusion and exclusion of subjects...
  12. doi request reprint Why carry out a longitudinal birth survey?
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:1-14. 2009
    ....
  13. doi request reprint Republished paper: Determinants of child health and development: the contribution of ALSPAC--a personal view of the birth cohort study
    Jean Golding
    Centre for Child and Adolescent Health, Barley House, Oakfield Grove, Clifton, Bristol BS8 2BN, UK
    Postgrad Med J 86:387-90. 2010
    ....
  14. doi request reprint High levels of depressive symptoms in pregnancy with low omega-3 fatty acid intake from fish
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Epidemiology 20:598-603. 2009
    ..We test the hypothesis that low seafood intake during pregnancy is associated with increased prevalence of depressive symptoms...
  15. doi request reprint Measuring outcomes in a longitudinal birth cohort
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:185-200. 2009
    ..Here we describe examples of the types of outcome that a birth cohort should collect, with emphasis on accuracy. We emphasise the use of continuous traits as well as of dichotomous outcomes, using a variety of examples...
  16. pmc Parental and grandparental ages in the autistic spectrum disorders: a birth cohort study
    Jean Golding
    Department of Community Based Medicine, University of Bristol, Centre for Child and Adolescent Health, Bristol, United Kingdom
    PLoS ONE 5:e9939. 2010
    ..A number of studies have assessed ages of parents of children with autistic spectrum disorders (ASD), and reported both maternal and paternal age effects. Here we assess relationships with grandparental ages...
  17. doi request reprint Determinants of child health and development: the contribution of ALSPAC--a personal view of the birth cohort study
    Jean Golding
    Centre for Child and Adolescent Health, Barley House, Oakfield Grove, Clifton, Bristol BS8 2BN, UK
    Arch Dis Child 95:319-22. 2010
    ....
  18. doi request reprint How many subjects are needed in a longitudinal birth cohort study?
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:31-8. 2009
    ..Here we describe ways in which different birth cohorts have addressed this issue and explore the advantages of smaller detailed studies over larger less-detailed studies...
  19. ncbi request reprint The Avon Longitudinal Study of Parents and Children (ALSPAC)--study design and collaborative opportunities
    Jean Golding
    Department of Community Based Medicine, 24 Tyndall Avenue, Bristol BS8 1TQ, UK
    Eur J Endocrinol 151:U119-23. 2004
    ..The quality of the data has proved high in validation studies and is maintained by collaboration with experts in each specialist field. The high participation rate ensures a viable study well into the future...
  20. doi request reprint Sources of data for a longitudinal birth cohort
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:51-62. 2009
    ..Although a longitudinal study could be carried out using just one type of data, greater depth and accuracy can be achieved by including a variety of different sources of information...
  21. doi request reprint Enrollment and response rates in a longitudinal birth cohort
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:73-85. 2009
    ..In this paper we outline various strategies that can be included in order to maximise the response rates...
  22. doi request reprint Associations between the ability to detect a bitter taste, dietary behavior, and growth: a preliminary report
    Jean Golding
    Centre for Child and Adolescent Health, University of Bristol, Bristol, United Kingdom
    Ann N Y Acad Sci 1170:553-7. 2009
    ..Children who were tasters (75% of sample) were slightly more likely to have been described as fussy eaters than the nontasters, and the supertasters were more likely to be in the lowest height decile at age 10...
  23. doi request reprint The importance of a genetic component in longitudinal birth cohorts
    Jean Golding
    Centre for Adolescent and Child Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:174-84. 2009
    ....
  24. doi request reprint Choice of environmental components for a longitudinal birth cohort study
    Jean Golding
    University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:134-53. 2009
    ..Long-term influences can even affect chronic diseases of adulthood. Here we describe the major psychosocial and physical environmental factors that should be measured in longitudinal birth cohort studies...
  25. doi request reprint Nesting sub-studies and randomised controlled trials within birth cohort studies
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:63-72. 2009
    ..For each category we give examples of ways in which they have been employed in current pregnancy birth cohort studies...
  26. doi request reprint Data organisation and preparation for statistical analysis in a longitudinal birth cohort
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:219-25. 2009
    ....
  27. doi request reprint The case for a coordinating centre for birth cohort studies
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:226-9. 2009
    ..The resource should be available for cohorts planned in the developed and developing world, as well as those countries in transition. We discuss possible strategies for funding such a centre...
  28. doi request reprint Preparation, piloting and validation for a longitudinal birth cohort study
    Jean Golding
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:201-12. 2009
    ..Because different measures will continually be introduced as the participants age, the preparation, piloting and validation studies have to be ongoing. Here we describe some of the different strategies that should be used...
  29. pmc Cohort Profile: the 'children of the 90s'--the index offspring of the Avon Longitudinal Study of Parents and Children
    Andy Boyd
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    Int J Epidemiol 42:111-27. 2013
    ..Data access is described in this article and is currently set up as a supported access resource. To date, over 700 peer-reviewed articles have been published using ALSPAC data...
  30. doi request reprint Early childhood risk factors associated with daytime wetting and soiling in school-age children
    Carol Joinson
    Department of Community Based Medicine, University of Bristol, Bristol, UK
    J Pediatr Psychol 33:739-50. 2008
    ..To examine the impact of a range of early childhood factors on the risk for daytime wetting and soiling...
  31. pmc Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Int J Epidemiol 42:97-110. 2013
    ..Details of how to access these data are provided in this cohort profile...
  32. doi request reprint Mental health difficulties in children with developmental coordination disorder
    Raghu Lingam
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Pediatrics 129:e882-91. 2012
    ..To explore the associations between probable developmental coordination disorder (DCD) defined at age 7 years and mental health difficulties at age 9 to 10 years...
  33. pmc Links between co-occurring social-communication and hyperactive-inattentive trait trajectories
    Beate St Pourcain
    Medical Research Council Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, UK
    J Am Acad Child Adolesc Psychiatry 50:892-902.e5. 2011
    ..We explored the interrelationship between trajectories of co-occurring symptoms, and sought evidence for shared prenatal/perinatal risk factors...
  34. doi request reprint The association between developmental coordination disorder and other developmental traits
    Raghu Lingam
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol BS6 6JS, United Kingdom
    Pediatrics 126:e1109-18. 2010
    ..To explore associations between developmental coordination disorder (DCD) and attention, language, social skills, and academic ability in a population-based cohort...
  35. doi request reprint Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age
    Colin D Steer
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom CDS and JG the Research Unit for Molecular Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany EL the Department of Pediatrics, Dr von Hauner Children s Hospital, University of Munich Medical Center, Munchen, Germany BK and the NIH, National Institute on Alcohol Abuse and Alcoholism, Bethesda MD JRH
    Am J Clin Nutr 98:1575-82. 2013
    ..Brain tissue is selectively enriched with highly unsaturated fatty acids (FAs). Altering the maternal FA status in pregnancy may improve fetal neural development with lasting consequences for child development...
  36. pmc Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence
    Beate St Pourcain
    The Medical Research Council Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Mol Autism 5:18. 2014
    ....
  37. pmc Dietary predictors of maternal prenatal blood mercury levels in the ALSPAC birth cohort study
    Jean Golding
    Centre for Child and Adolescent Health, University of Bristol, Bristol, United Kingdom
    Environ Health Perspect 121:1214-8. 2013
    ..It has been suggested that all possible sources of mercury should be avoided. However, although seafood is a known source of mercury, little is known about other dietary components that contribute to the overall levels of blood mercury...
  38. pmc Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study
    Dheeraj Rai
    Centre for Mental Health, Addiction and Suicide Research, School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK
    BMJ 346:f2059. 2013
    ..To study the association between parental depression and maternal antidepressant use during pregnancy with autism spectrum disorders in offspring...
  39. pmc Common variation contributes to the genetic architecture of social communication traits
    Beate St Pourcain
    MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Mol Autism 4:34. 2013
    ..Social communication difficulties represent an autistic trait that is highly heritable and persistent during the course of development. However, little is known about the underlying genetic architecture of this phenotype...
  40. pmc Differences between blood donors and a population sample: implications for case-control studies
    Jean Golding
    School of Social and Community Medicine, University of Bristol, Bristol, UK, MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK, and Institute of Child Health, University College London, London, UK
    Int J Epidemiol 42:1145-56. 2013
    ..Selecting appropriate controls for studies of genetic variation in case series is important. The two major candidates involve the use of blood donors or a random sample of the population...
  41. pmc Prenatal alcohol exposure and offspring cognition and school performance. A 'Mendelian randomization' natural experiment
    Luisa Zuccolo
    MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK, School of Social and Community Medicine, University of Bristol, Bristol, UK, Section of Developmental Psychiatry, University of Nottingham, Nottingham, UK, Department of Health Sciences, University of Leicester, Leicester, UK, School of Medicine, University of Sheffield, Sheffield, UK, Clinical Genetics, University Hospitals of Leicester, Leicester, UK, School of Population Health, University of Queensland, Brisbane, Queensland, Australia and National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK
    Int J Epidemiol 42:1358-70. 2013
    ..The authors aimed to investigate the unconfounded effect of moderately increased prenatal alcohol exposure on cognitive/educational performance...
  42. pmc Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms
    Colin D Steer
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK
    Hum Mol Genet 21:1504-12. 2012
    ..However, by 7 years, no associations were observed with the maternal genotype. This suggested that the children's FA levels were related only to their own metabolism with no apparent lasting influences of the in utero environment...
  43. pmc Association between a high-risk autism locus on 5p14 and social communication spectrum phenotypes in the general population
    Beate St Pourcain
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK
    Am J Psychiatry 167:1364-72. 2010
    ..This study investigated whether rs4307059 also operates as a quantitative trait locus underlying a broader autism phenotype in the general population, focusing specifically on the social communication aspect of the spectrum...
  44. ncbi request reprint A prospective study of age at initiation of toilet training and subsequent daytime bladder control in school-age children
    Carol Joinson
    Department of Community Based Medicine, University of Bristol, Cotham Hill, Bristol, United Kingdom
    J Dev Behav Pediatr 30:385-93. 2009
    ..The main aim is to examine whether initiation of toilet training after 24 months is associated with increased odds of daytime wetting in school-age children...
  45. doi request reprint Feeding symptoms, dietary patterns, and growth in young children with autism spectrum disorders
    Alan Emond
    Centre for Child and Adolescent Health, Barley House, Oakfield Grove, Bristol, UK
    Pediatrics 126:e337-42. 2010
    ..To investigate the feeding, diet and growth of young children with autism spectrum disorders (ASD)...
  46. pmc Dependence of deodorant usage on ABCC11 genotype: scope for personalized genetics in personal hygiene
    Santiago Rodriguez
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, and Bristol Genetic Epidemiology Laboratories BGEL, School of Social and Community Medicine, University of Bristol, Bristol, UK
    J Invest Dermatol 133:1760-7. 2013
    ..It also indicates potential cost saving to the nonodorous and scope for personalized genetics usage in personal hygiene choices, with consequent reduction of inappropriate chemical exposures for some...
  47. pmc Fetal alcohol exposure and IQ at age 8: evidence from a population-based birth-cohort study
    Sarah J Lewis
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e49407. 2012
    ..Associations between children's cognitive function and both maternal and child genotype at these loci can shed light on the effects of maternal alcohol consumption on offspring cognitive development...
  48. doi request reprint Parental accounts of the prevalence, causes and treatments of limb pain in children aged 5 to 13 years: a longitudinal cohort study
    Jackie L Bishop
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Clifton, Bristol BS8 2PS, UK
    Arch Dis Child 97:52-3. 2012
    ..Limb pain prevalence may have been under-reported in this study due to gradual attrition, particularly in the less educated mothers among whom the highest prevalence of limb pain was reported...
  49. ncbi request reprint Prenatal alcohol exposure and gender differences in childhood mental health problems: a longitudinal population-based study
    Kapil Sayal
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Hampton House, Cotham Hill, Bristol BS6 6JS, United Kingdom
    Pediatrics 119:e426-34. 2007
    ..We expected that only higher levels of alcohol consumption would be associated with later mental health problems and that any associations might be more readily detectable in boys...
  50. ncbi request reprint Child maltreatment in the "Children of the Nineties:" deprivation, class, and social networks in a UK sample
    Peter Sidebotham
    Unit of Paediatric and Perinatal Epidemiology, Institute of Child Health, University of Bristol, St Michael s Hill, BS2 8BJ, Bristol, UK
    Child Abuse Negl 26:1243-59. 2002
    ..To determine risk factors for child maltreatment within the socio-economic environment of a contemporary UK child population...
  51. ncbi request reprint Thimerosal exposure in infants and developmental disorders: a prospective cohort study in the United kingdom does not support a causal association
    Jon Heron
    Unit of Paediatric and Perinatal Epidemiology, Department of Community Based Medical Sciences, University of Bristol, Bristol, United Kingdom
    Pediatrics 114:577-83. 2004
    ..The aim of this research was to test in a large United Kingdom population-based cohort whether there is any evidence to justify such concerns...
  52. pmc Dental associations with blood mercury in pregnant women
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Community Dent Oral Epidemiol 44:216-22. 2016
    ..This study therefore sets out to determine the extent to which dental amalgam (DA) may contribute to total blood mercury (TBHg) levels of pregnant women in the UK...
  53. pmc FADS2 polymorphisms modify the effect of breastfeeding on child IQ
    Colin D Steer
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    PLoS ONE 5:e11570. 2010
    ..A study by Caspi et al has suggested that rs174575 within the FADS2 gene moderates this effect so that children homozygous in the minor allele (GG genotype) have similar IQs irrespective of feeding method...
  54. doi request reprint Choosing the types of biological sample to collect in longitudinal birth cohort studies
    Richard Jones
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 23:103-13. 2009
    ..Here we outline those that are particularly useful in longitudinal birth cohort studies starting in pregnancy, and discuss their advantages and disadvantages...
  55. pmc Data relating to early child development in the Avon Longitudinal Study of Parents and Children (ALSPAC), their relationship with prenatal blood mercury and stratification by fish consumption
    Yasmin Iles-Caven
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, UK
    Data Brief 9:112-22. 2016
    ..For results, please see doi:10.1016/j.neuro.2016.02.006 [1].). ..
  56. pmc Environmental factors predicting blood lead levels in pregnant women in the UK: the ALSPAC study
    Caroline M Taylor
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 8:e72371. 2013
    ..The behaviour and academic performance of children can be adversely affected even at low blood lead levels (BLL) of 5-10 µg/dl. An important contribution to the infant's lead load is provided by maternal transfer during pregnancy...
  57. pmc The anthropometry of children and adolescents may be influenced by the prenatal smoking habits of their grandmothers: a longitudinal cohort study
    Jean Golding
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, BS8 2BN, United Kingdom
    Am J Hum Biol 26:731-9. 2014
    ..The findings raised the question as to whether there were long-term associations on the growth of the study children over time...
  58. pmc Prepubertal start of father's smoking and increased body fat in his sons: further characterisation of paternal transgenerational responses
    Kate Northstone
    School of Social and Community Medicine, University of Bristol, London, UK
    Eur J Hum Genet 22:1382-6. 2014
    ..Smoking by boys in mid childhood may contribute to obesity in adolescent boys of the next generation. ..
  59. pmc Traits contributing to the autistic spectrum
    Colin D Steer
    Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 5:e12633. 2010
    ..It is increasingly recognised that traits associated with autism reflect a spectrum with no clear boundary between typical and atypical behaviour. Dimensional traits are needed to investigate the broader autism phenotype...
  60. pmc Is the growth of the child of a smoking mother influenced by the father's prenatal exposure to tobacco? A hypothesis generating longitudinal study
    Marcus Pembrey
    School of Social and Community Medicine, University of Bristol, Bristol, UK Centre for Child and Adolescent Health, University of Bristol, Bristol, UK Institute of Child Health, University College London, London, UK
    BMJ Open 4:e005030. 2014
    ..The aim of this study was to determine whether the prenatal smoke exposure of either parent influenced the growth of the fetus of a smoking woman, and whether any effects were dependent on the fetal sex...
  61. doi request reprint Prevalence of developmental coordination disorder using the DSM-IV at 7 years of age: a UK population-based study
    Raghu Lingam
    Centre for Child and Adolescent Health, Department of Community Based Medicine, University of Bristol, Bristol B566JS, United Kingdom
    Pediatrics 123:e693-700. 2009
    ..To calculate the prevalence of developmental coordination disorder at 7 years of age by using Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria in a large UK birth cohort...
  62. pmc Is the growth of the fetus of a non-smoking mother influenced by the smoking of either grandmother while pregnant?
    Laura L Miller
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 9:e86781. 2014
    ..Here we assess whether prenatal exposure of either parent to cigarette smoke has a sex-specific effect on the grandchild's birth measurements...
  63. ncbi request reprint The search for genenotype/phenotype associations and the phenome scan
    Richard Jones
    ALSPAC, Department of Community Based Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 19:264-75. 2005
    ..We believe that this approach can generate data that will be useful in answering generic questions about genotype/phenotype associations as well as in discovering novel ones...
  64. ncbi request reprint Sex-specific, male-line transgenerational responses in humans
    Marcus E Pembrey
    Clinical and Molecular Genetics Unit, Institute of Child Health, University College London, England, UK
    Eur J Hum Genet 14:159-66. 2006
    ..Such responses add an entirely new dimension to the study of gene-environment interactions in development and health...
  65. pmc Are prenatal mercury levels associated with subsequent blood pressure in childhood and adolescence? The Avon prebirth cohort study
    Steve Gregory
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMJ Open 6:e012425. 2016
    ..We therefore analysed a large prospective population study to investigate whether prenatal mercury exposure might influence offspring blood pressure (BP) and heart rate adversely...
  66. pmc Low level lead exposure and pregnancy outcomes in an observational birth cohort study: dose-response relationships
    Caroline M Taylor
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    BMC Res Notes 9:291. 2016
    ..Our aim was to investigate whether there was evidence for a differential effect of maternal Pb levels on birth outcomes and/or a threshold value for effects...
  67. pmc Prenatal and early life exposure to stressful life events and risk of autism spectrum disorders: population-based studies in Sweden and England
    Dheeraj Rai
    Academic Unit of Psychiatry, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e38893. 2012
    ..We tested the hypothesis that maternal exposure to stressful life events would be associated with increased risks of offspring ASD, and that these risks would be highest for exposures during the prenatal period...
  68. ncbi request reprint A United Kingdom population-based study of intellectual capacities in children with and without soiling, daytime wetting, and bed-wetting
    Carol Joinson
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Pediatrics 120:e308-16. 2007
    ..The objective of this study was to examine differences in intellectual capacities between children with and without soiling, daytime wetting, and bed-wetting...
  69. pmc IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children
    Amy E Taylor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Biol Psychiatry 70:152-8. 2011
    ..Although there is also evidence of milder cognitive impairment in later life in carriers of the APOE ε4 allele, there have been few studies investigating the impact of APOE genotype on cognitive function in children...
  70. ncbi request reprint Early feeding problems in children with cerebral palsy: weight and neurodevelopmental outcomes
    Sara Motion
    Unit of Paediatric and Perinatal Epidemiology, Institute of Child Health, Bristol, UK
    Dev Med Child Neurol 44:40-3. 2002
    ..005) at 8 years of age. Early, persistent, and severe feeding difficulties are a marker for subsequent poor growth, feeding, and developmental outcomes and can identify children with CP who will benefit from gastrostomy feeding...
  71. pmc Digit ratio and autism spectrum disorders in the Avon Longitudinal Study of Parents and Children: a birth cohort study
    Anna Louise Guyatt
    Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol, UK MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMJ Open 5:e007433. 2015
    ..To investigate whether second-to-fourth digit ratio (2D:4D), a measure commonly used as a proxy for fetal testosterone exposure, is associated with autism spectrum disorders (ASDs), as predicted by the extreme male brain theory of autism...
  72. pmc Balance ability in 7- and 10-year-old children: associations with prenatal lead and cadmium exposure and with blood lead levels in childhood in a prospective birth cohort study
    Caroline M Taylor
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMJ Open 5:e009635. 2015
    ..The aim of the study was to identify the associations of lead (in utero and in childhood) and cadmium (in utero) exposure with the ability to balance in children aged 7 and 10 years...
  73. doi request reprint Intake of game birds in the UK: assessment of the contribution to the dietary intake of lead by women of childbearing age and children
    Caroline M Taylor
    Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Public Health Nutr 17:1125-9. 2014
    ..Concern has recently been expressed about Pb levels in Pb-shot game meat. Our aim was to determine the consumption of game birds in a representative sample population in the UK, and in children and women of childbearing age in particular...
  74. doi request reprint Social and behavioural outcomes in children diagnosed with autism spectrum disorders: a longitudinal cohort study
    Ginny Russell
    ESRC Centre for Genomics in Society, University of Exeter, Exeter, UK
    J Child Psychol Psychiatry 53:735-44. 2012
    ..To compare social and behavioural outcomes between children formally diagnosed with autism spectrum disorders (ASD) with those of children who displayed autistic traits at preschool age, but remained undiagnosed as teenagers...
  75. ncbi request reprint The course of anxiety and depression through pregnancy and the postpartum in a community sample
    Jonathan Heron
    University of Bristol, UK
    J Affect Disord 80:65-73. 2004
    ..Postnatal and antenatal depression are a focus of considerable clinical and research attention, but little is known about the patterns of anxiety across this period...
  76. pmc Pregnancy diet and associated outcomes in the Avon Longitudinal Study of Parents and Children
    Pauline M Emmett
    P M Emmett and J Golding are with the Centre for Child and Adolescent Health, School of Social and Community Medicine, University of Bristol, Bristol, UK L R Jones is with the School of Social and Community Medicine, University of Bristol, Bristol, UK
    Nutr Rev 73:154-74. 2015
    ..The findings from the Avon Longitudinal Study of Parents and Children strengthen the recommendation to eat fish regularly during pregnancy. ..
  77. pmc Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence
    Beate St Pourcain
    MRC Integrative Epidemiology Unit MRC IEU, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Hum Genet 134:539-51. 2015
    ..In summary, our findings suggest that problematic peer relationships are heritable but genetically complex and heterogeneous from age to age, with an increase in common measurable genetic variation during adolescence...
  78. pmc Preconception and prenatal environmental factors associated with communication impairments in 9 year old children using an exposome-wide approach
    Colin D Steer
    MRC integrative epidemiological unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 10:e0118701. 2015
    ..Finally, there may be a mechanism via the maternal diet in pregnancy in particular the consumption of fatty or processed foods. This is the subject of ongoing investigation. ..
  79. pmc Glue ear, hearing loss and IQ: an association moderated by the child's home environment
    Amanda J Hall
    Children s Hearing Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom Centre for Hearing and Balance Studies, University of Bristol, Bristol, United Kingdom
    PLoS ONE 9:e87021. 2014
    ..For most children it has no long lasting effects on cognitive development but it is unclear whether there are subgroups at higher risk of sequelae...
  80. ncbi request reprint The effects of child sexual abuse in later family life; mental health, parenting and adjustment of offspring
    Ron Roberts
    Department of Psychology, Kingston University, Kingston, Surrey KT1 2EE, UK
    Child Abuse Negl 28:525-45. 2004
    ..To investigate links between child sexual abuse (occurring before 13 years), later mental health, family organization, parenting behaviors, and adjustment in offspring...
  81. ncbi request reprint Alcohol, breastfeeding, and development at 18 months
    Ruth E Little
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Pediatrics 109:E72-2. 2002
    ..We aimed to replicate a previous study of 1-year-olds that reported a deficit in motor development associated with moderate alcohol use during lactation, using a different but comparable population...
  82. ncbi request reprint Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Report from the Avon Longitudinal Study of Parents and Children
    Thomas G O'Connor
    Institute of Psychiatry, Denmark Hill, London
    Br J Psychiatry 180:502-8. 2002
    ..Animal experiments suggest that maternal stress and anxiety during pregnancy have long-term effects on the behaviour of the offspring...
  83. ncbi request reprint Prolonged use of oral contraception before a planned pregnancy is associated with a decreased risk of delayed conception
    Alexandra Farrow
    Department of Health and Social Care, Brunel University, Borough Rd, Isleworth TW7 5DU, UK
    Hum Reprod 17:2754-61. 2002
    ..The aim of this study was to investigate the association of total duration of oral contraceptive usage with time to conception...
  84. ncbi request reprint Factors associated with the development of peanut allergy in childhood
    Gideon Lack
    Department of Paediatric Allergy and Immunology, St Mary s Hospital at Imperial College, London, United Kingdom
    N Engl J Med 348:977-85. 2003
    ..The prevalence of peanut allergy appears to have increased in recent decades. Other than a family history of peanut allergy and the presence of atopy, there are no known risk factors...
  85. ncbi request reprint Twins as a natural experiment to study the causes of mild language delay: I: Design; twin-singleton differences in language, and obstetric risks
    Michael Rutter
    Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 44:326-41. 2003
    ..The present study was designed to pit these alternatives against one another as possible causal influences...
  86. ncbi request reprint Fish intake during pregnancy and early cognitive development of offspring
    Julie L Daniels
    National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA juliedanielsunc edu
    Epidemiology 15:394-402. 2004
    ..Previous investigations of fish intake in relation to neurodevelopment have focused on possible damage from contaminants, whereas potential benefits of fish consumption have been relatively unexplored..
  87. ncbi request reprint Maternal antenatal anxiety and behavioural/emotional problems in children: a test of a programming hypothesis
    Thomas G O'Connor
    Department of Child and Adolescent Psychiatry, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 44:1025-36. 2003
    ..Previous animal investigations link antenatal stress with a range of persistent behavioural abnormalities in the offspring. The current study examined if the effect was also found in humans through middle childhood...
  88. ncbi request reprint Nocturnal enuresis at 7.5 years old: prevalence and analysis of clinical signs
    Richard J Butler
    Clinical Psychology, Child and Adolescent Mental Health Services, East Leeds Primary Care Trust, Leeds, UK
    BJU Int 96:404-10. 2005
    ..5 years old, and to examine the frequency of variables such as gender, severity, associated elimination problems, and clinical signs within the identified group...
  89. ncbi request reprint Prenatal anxiety predicts individual differences in cortisol in pre-adolescent children
    Thomas G O'Connor
    Department of Psychiatry, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, NY 14642, USA
    Biol Psychiatry 58:211-7. 2005
    ..This study examined the long-term association between prenatal anxiety and measures of diurnal cortisol at age 10 years...
  90. ncbi request reprint Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children
    Jennifer H Barnett
    University of Cambridge, Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Am J Psychiatry 164:142-9. 2007
    ..This polymorphism affects cognitive function in healthy adults and may contribute to risk for schizophrenia...
  91. pmc Earlier mother's age at menarche predicts rapid infancy growth and childhood obesity
    Ken K Ong
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    PLoS Med 4:e132. 2007
    ..As age at menarche is a heritable trait, we hypothesised that age at menarche in the mother may in turn predict her children's early growth and obesity risk...
  92. ncbi request reprint Maternal childhood abuse and offspring adjustment over time
    Stephan Collishaw
    MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Dev Psychopathol 19:367-83. 2007
    ..The ALSPAC study team comprises interviewers, computer technicians, laboratory technicians, clerical workers, research scientists, volunteers, and managers who continue to make the study possible...
  93. ncbi request reprint Genetic regulation of birth weight and fasting glucose by a common polymorphism in the islet cell promoter of the glucokinase gene
    Michael N Weedon
    Institute of Biomedical and Clinical Science, Peninsula Medical School, Barrack Road, Exeter EX2 5AX, U K
    Diabetes 54:576-81. 2005
    ..This study establishes that common genetic variation, in addition to rare mutations and environmental factors, can affect both FPG and birth weight...
  94. ncbi request reprint Which children receive grandparental care and what effect does it have?
    Emma Fergusson
    Park Hospital, Headington, Oxford, UK
    J Child Psychol Psychiatry 49:161-9. 2008
    ..Grandparents are increasingly involved in the care of young children, but little is known about factors associated with this type of care, or its implications for children's behavioural development...
  95. ncbi request reprint Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, US National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, Bethesda, MD 20952, USA
    Lancet 369:578-85. 2007
    ..We used the Avon Longitudinal Study of Parents and Children (ALSPAC) to assess the possible benefits and hazards to a child's development of different levels of maternal seafood intake during pregnancy...
  96. ncbi request reprint Use and storage of domestic pesticides in the UK
    Charlotte N B Grey
    Department of Environmental Science and Technology, Imperial College, London, UK
    Sci Total Environ 368:465-70. 2006
    ..Over 85 different pesticide products were found to be stored in 76% of homes, with 76 different types of pesticide active ingredients. Insecticides were the most commonly used and stored pesticide...
  97. ncbi request reprint The predictive value of early life total immunoglobulin E measurement in identifying atopic children in a population-based birth cohort study
    Michael R Perkin
    Department of Child Health, St George s, University of London, London, UK
    Pediatr Allergy Immunol 17:118-24. 2006
    ..5% and a specificity of 95.8%. Although significant differences in early life IgE measurements were seen, the extent of overlap was great, such that the overall performance of IgE at 12 months as a screening test for atopy was poor...
  98. ncbi request reprint The use and disposal of household pesticides
    Charlotte N B Grey
    Department of Environmental Science and Technology, Royal School of Mines, Imperial College, Prince Consort Road, Room 415, London SW7 2AZ, UK
    Environ Res 97:109-15. 2005
    ..It is a public health concern that the instructions on the labels of products may not always be understood or followed, and further understanding of user behaviour is needed...
  99. pmc Maternal dental history, child's birth outcome and early cognitive development
    Julie L Daniels
    Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Paediatr Perinat Epidemiol 21:448-57. 2007
    ..9, [95% confidence interval 1.0, 3.4]). More detailed evaluation of the potential adverse effects of elective dental treatment during pregnancy, particularly dental X-rays, may be warranted...