P R Gard

Summary

Affiliation: University of Brighton
Country: UK

Publications

  1. doi request reprint Changes of renin-angiotensin system-related aminopeptidases in early stage Alzheimer's disease
    Paul Richard Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK Electronic address
    Exp Gerontol . 2017
  2. doi request reprint Blockade of pro-cognitive effects of angiotensin IV and physostigmine in mice by oxytocin antagonism
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton, BN2 4GJ, UK
    Eur J Pharmacol 683:155-60. 2012
  3. doi request reprint Non-adherence to antihypertensive medication and impaired cognition: which comes first?
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
    Int J Pharm Pract 18:252-9. 2010
  4. pmc Cognitive-enhancing effects of angiotensin IV
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton, UK
    BMC Neurosci 9:S15. 2008
  5. ncbi request reprint Interactions of angiotensin IV and oxytocin on behaviour in mice
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
    J Renin Angiotensin Aldosterone Syst 8:133-8. 2007
  6. ncbi request reprint Angiotensin and Alzheimer's disease: therapeutic prospects
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, BN2 4GJ, UK
    Expert Rev Neurother 4:87-96. 2004
  7. ncbi request reprint Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression
    Paul R Gard
    University of Brighton, School of Pharmacy and Biomolecular Sciences, UK
    Expert Opin Ther Targets 8:7-14. 2004
  8. ncbi request reprint The role of angiotensin II in cognition and behaviour
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton BN2 4GJ, UK
    Eur J Pharmacol 438:1-14. 2002
  9. ncbi request reprint Strain differences in the anxiolytic effects of losartan in the mouse
    P R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, BN2 4GJ, Brighton, UK
    Pharmacol Biochem Behav 69:35-40. 2001
  10. ncbi request reprint Use of chlorhexidine-releasing nylon fibres to reduce device-related uterine infections
    P R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, UK
    Gynecol Obstet Invest 49:261-5. 2000

Collaborators

Detail Information

Publications14

  1. doi request reprint Changes of renin-angiotensin system-related aminopeptidases in early stage Alzheimer's disease
    Paul Richard Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK Electronic address
    Exp Gerontol . 2017
    ....
  2. doi request reprint Blockade of pro-cognitive effects of angiotensin IV and physostigmine in mice by oxytocin antagonism
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton, BN2 4GJ, UK
    Eur J Pharmacol 683:155-60. 2012
    ....
  3. doi request reprint Non-adherence to antihypertensive medication and impaired cognition: which comes first?
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
    Int J Pharm Pract 18:252-9. 2010
    ..This study assessed the evidence that antihypertensive medications have effects on the prevalence or severity of mild cognitive impairment, dementia or Alzheimer's disease...
  4. pmc Cognitive-enhancing effects of angiotensin IV
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton, UK
    BMC Neurosci 9:S15. 2008
    ..At present it thus appears that those individuals with the poorest baseline cognition may receive greatest benefit, but possible genetic differences in responses to angiotensin IV cannot be ruled-out...
  5. ncbi request reprint Interactions of angiotensin IV and oxytocin on behaviour in mice
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
    J Renin Angiotensin Aldosterone Syst 8:133-8. 2007
    ..Oxytocin (OT) also influences learning and memory in rats and mice and, in the light of the proposed effects of Ang IV on oxytocinase, the hypothesis that the effects of Ang IV on cognition in mice involve OT was tested...
  6. ncbi request reprint Angiotensin and Alzheimer's disease: therapeutic prospects
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, BN2 4GJ, UK
    Expert Rev Neurother 4:87-96. 2004
    ....
  7. ncbi request reprint Angiotensin as a target for the treatment of Alzheimer's disease, anxiety and depression
    Paul R Gard
    University of Brighton, School of Pharmacy and Biomolecular Sciences, UK
    Expert Opin Ther Targets 8:7-14. 2004
    ..Such effects, if proven, could promote the use of such agents in the treatment of hypertension coexisting with depression or anxiety...
  8. ncbi request reprint The role of angiotensin II in cognition and behaviour
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton BN2 4GJ, UK
    Eur J Pharmacol 438:1-14. 2002
    ..The role of the brain renin-angiotensin system in human psychopathology remains to be fully explored...
  9. ncbi request reprint Strain differences in the anxiolytic effects of losartan in the mouse
    P R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, BN2 4GJ, Brighton, UK
    Pharmacol Biochem Behav 69:35-40. 2001
    ....
  10. ncbi request reprint Use of chlorhexidine-releasing nylon fibres to reduce device-related uterine infections
    P R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton, UK
    Gynecol Obstet Invest 49:261-5. 2000
    ..These findings indicate that chlorhexidine-releasing devices are potentially useful in the reduction of device-related infections...
  11. doi request reprint Assessment of biological activity of novel peptide analogues of angiotensin IV
    Paul R Gard
    School of Pharmacy and Biomolecular Sciences, University of Brighton Brighton and Sussex Medical School, University of Sussex, Brighton, UK
    J Pharm Pharmacol 63:565-71. 2011
    ..Ang IV improves cognition in animal models thus there is a desire to develop metabolically stable analogues for further development...
  12. ncbi request reprint The development of in vitro biocompatibility tests for the evaluation of intraocular biomaterials
    A W Lloyd
    Drug Delivery and Biomaterials Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Moulsecoomb, Brighton BN2 4GJ, UK
    J Mater Sci Mater Med 10:621-7. 1999
    ..These assays offer a more relevant means of assessing the ocular compatibility of biomaterials than those presently required by the authorities for regulatory approval of medical devices and implants...
  13. ncbi request reprint In vitro cytotoxicity and teratogenicity of norethisterone and levonorgestrel released from hollow nylon monofilaments
    S N Ostad
    Department of Pharmacy, University of Brighton, Moulsecoomb, UK
    J Control Release 50:179-86. 1998
    ..These results suggest that the hollow nylon fibres may be of use for the delivery of norethisterone to the uterus but that they are inappropriate for the delivery of levonorgestrel...
  14. ncbi request reprint Renin-angiotensin-system gene polymorphisms and depression
    Yolande B Saab
    School of Pharmacy, Lebanese American University, Byblos, Lebanon
    Prog Neuropsychopharmacol Biol Psychiatry 31:1113-8. 2007
    ..The results support the hypothesis that increased RAS activity may increase relative risk of depression in that the angiotensin receptor type 1 (A1166C) CC genotype is associated with increased responsiveness to angiotensin II...