Abigail Fraser

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Bristol, England
    Gastroenterology 133:1814-20. 2007
  2. ncbi The associations between height components (leg and trunk length) and adult levels of liver enzymes
    A Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    J Epidemiol Community Health 62:48-53. 2008
  3. ncbi Antibiotics for preventing meningococcal infections
    A Fraser
    University of Bristol, Canynge Hall, Department of Social Medicine, Whiteladies Road, Bristol, UK
    Cochrane Database Syst Rev . 2006
  4. ncbi Vaccines for preventing typhoid fever
    A Fraser
    University of Bristol, Canynge Hall, Department of Social Medicine, Whiteladies Road, Bristol, UK, BS8 2PR
    Cochrane Database Syst Rev . 2007
  5. pmc Long-term health outcomes in offspring born to women with diabetes in pregnancy
    Abigail Fraser
    MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Curr Diab Rep 14:489. 2014
  6. pmc Maternal diabetes in pregnancy and offspring cognitive ability: sibling study with 723,775 men from 579,857 families
    Abigail Fraser
    MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Diabetologia 57:102-9. 2014
  7. pmc Hypertensive disorders of pregnancy and cardiometabolic health in adolescent offspring
    Abigail Fraser
    MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Hypertension 62:614-20. 2013
  8. pmc Associations of pregnancy complications with calculated cardiovascular disease risk and cardiovascular risk factors in middle age: the Avon Longitudinal Study of Parents and Children
    Abigail Fraser
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom
    Circulation 125:1367-80. 2012
  9. pmc Associations of serum 25-hydroxyvitamin D, parathyroid hormone and calcium with cardiovascular risk factors: analysis of 3 NHANES cycles (2001-2006)
    Abigail Fraser
    Department of Social Medicine, Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    PLoS ONE 5:e13882. 2010
  10. pmc Associations of gestational weight gain with maternal body mass index, waist circumference, and blood pressure measured 16 y after pregnancy: the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology and the School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 93:1285-92. 2011

Detail Information

Publications70

  1. pmc Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Bristol, England
    Gastroenterology 133:1814-20. 2007
    ..Study aims were to estimate the prevalence of elevated alanine aminotransferase (ALT, as a marker of NAFLD) in a general contemporary adolescent population and to identify leading risk factors for ALT elevation (>30 U/L)...
  2. ncbi The associations between height components (leg and trunk length) and adult levels of liver enzymes
    A Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    J Epidemiol Community Health 62:48-53. 2008
    ....
  3. ncbi Antibiotics for preventing meningococcal infections
    A Fraser
    University of Bristol, Canynge Hall, Department of Social Medicine, Whiteladies Road, Bristol, UK
    Cochrane Database Syst Rev . 2006
    ....
  4. ncbi Vaccines for preventing typhoid fever
    A Fraser
    University of Bristol, Canynge Hall, Department of Social Medicine, Whiteladies Road, Bristol, UK, BS8 2PR
    Cochrane Database Syst Rev . 2007
    ..Two typhoid vaccines are commercially available, Ty21a (oral) and Vi polysaccharide (parenteral), but neither is used routinely. Other vaccines, such as a new modified, conjugated Vi vaccine called Vi-rEPA, are in development...
  5. pmc Long-term health outcomes in offspring born to women with diabetes in pregnancy
    Abigail Fraser
    MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Curr Diab Rep 14:489. 2014
    ....
  6. pmc Maternal diabetes in pregnancy and offspring cognitive ability: sibling study with 723,775 men from 579,857 families
    Abigail Fraser
    MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Diabetologia 57:102-9. 2014
    ....
  7. pmc Hypertensive disorders of pregnancy and cardiometabolic health in adolescent offspring
    Abigail Fraser
    MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Hypertension 62:614-20. 2013
    ..Results suggest a specific association between maternal hypertensive disorders of pregnancy and offspring blood pressure that may be driven by genetics or familial nongenetic risk factors particular to blood pressure. ..
  8. pmc Associations of pregnancy complications with calculated cardiovascular disease risk and cardiovascular risk factors in middle age: the Avon Longitudinal Study of Parents and Children
    Abigail Fraser
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom
    Circulation 125:1367-80. 2012
    ..The nature and contribution of different pregnancy-related complications to future cardiovascular disease (CVD) and its risk factors and the mechanisms underlying these associations remain unclear...
  9. pmc Associations of serum 25-hydroxyvitamin D, parathyroid hormone and calcium with cardiovascular risk factors: analysis of 3 NHANES cycles (2001-2006)
    Abigail Fraser
    Department of Social Medicine, Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    PLoS ONE 5:e13882. 2010
    ..25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), and calcium may be directly associated with cardiovascular risk factors or mediated by each other...
  10. pmc Associations of gestational weight gain with maternal body mass index, waist circumference, and blood pressure measured 16 y after pregnancy: the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology and the School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 93:1285-92. 2011
    ..Little is known about associations of gestational weight gain (GWG) with long-term maternal health...
  11. pmc Alanine aminotransferase, gamma-glutamyltransferase (GGT) and all-cause mortality: results from a population-based Danish twins study alanine aminotransferase, GGT and mortality in elderly twins
    Abigail Fraser
    Department of Social Medicine, MRC Centre for Causal Analysis in Translational Epidemiology, University of Bristol, Bristol BS8 2BN, UK
    Liver Int 29:1494-9. 2009
    ..None of these studies controlled for genetic variation as well as fetal and early life exposure, whether environmental or genetic...
  12. pmc Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis
    Abigail Fraser
    Departmentof Social Medicine, Medical Research Council Centre for Causal Analysis in Translational Epidemiology, University of Bristol, Bristol, UK
    Diabetes Care 32:741-50. 2009
    ..To estimate and compare associations of alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) with incident diabetes...
  13. doi A modified Mediterranean diet is associated with the greatest reduction in alanine aminotransferase levels in obese type 2 diabetes patients: results of a quasi-randomised controlled trial
    A Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    Diabetologia 51:1616-22. 2008
    ..The aim of the study was to compare the effect of different dietary interventions on alanine aminotransferase (ALT) in obese patients with diabetes...
  14. doi Interleukin-6 and incident coronary heart disease: results from the British Women's Heart and Health Study
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Atherosclerosis 202:567-72. 2009
    ..The purpose of this study was to determine whether IL-6 is associated with incident coronary heart disease (CHD) events independently of established risk factors and to examine its predictive ability for future CHD events...
  15. doi Early life growth and hemostatic factors: the Barry Caerphilly Growth study
    A Fraser
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Am J Epidemiol 168:179-87. 2008
    ..11, 95% CI: 1.01, 1.23). Results support the view that the immediate postnatal period may be particularly important, possibly through impaired liver development and/or infection in early life, in determining cardiovascular disease risk...
  16. doi The associations between birthweight and adult markers of liver damage and function
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 22:12-21. 2008
    ....
  17. ncbi Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS8 2PR, UK
    Arterioscler Thromb Vasc Biol 27:2729-35. 2007
    ..Alanine aminotransferase (ALT) is the enzyme most closely associated with liver fat content...
  18. ncbi Typhoid fever vaccines: systematic review and meta-analysis of randomised controlled trials
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Vaccine 25:7848-57. 2007
    ..Neither vaccine is currently registered for administration to children below 2 years of age. Given the recent finding that typhoid fever also affects infants, development of a conjugate vaccine is warranted...
  19. ncbi A comparison of associations of alanine aminotransferase and gamma-glutamyltransferase with fasting glucose, fasting insulin, and glycated hemoglobin in women with and without diabetes
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Bristol UK
    Hepatology 46:158-65. 2007
    ..Associations did not differ substantially between obese and non-obese non-diabetic women...
  20. pmc Cohort Profile: the 'children of the 90s'--the index offspring of the Avon Longitudinal Study of Parents and Children
    Andy Boyd
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    Int J Epidemiol 42:111-27. 2013
    ..Data access is described in this article and is currently set up as a supported access resource. To date, over 700 peer-reviewed articles have been published using ALSPAC data...
  21. pmc Associations of gestational diabetes, existing diabetes, and glycosuria with offspring obesity and cardiometabolic outcomes
    Sumaiya Patel
    MRC Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Diabetes Care 35:63-71. 2012
    ..To assess associations of gestational diabetes, existing diabetes, and glycosuria with adiposity and cardiometabolic risk factors in offspring at adolescence...
  22. pmc Association of maternal diabetes/glycosuria and pre-pregnancy body mass index with offspring indicators of non-alcoholic fatty liver disease
    Sumaiya Patel
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Road, Bristol, UK
    BMC Pediatr 16:47. 2016
    ..We examined associations of maternal pregnancy diabetes/glycosuria and pre-pregnancy body mass index (BMI) with offspring markers of NAFLD and liver pathology and examined mediation by birthweight and concurrent offspring adiposity...
  23. pmc Associations of maternal 25-hydroxyvitamin D in pregnancy with offspring cardiovascular risk factors in childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children
    Dylan M Williams
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Heart 99:1849-56. 2013
    ..We examined associations of maternal total 25-hydroxyvitamin D (25(OH)D) in pregnancy with offspring cardiovascular risk factors assessed in childhood and adolescence...
  24. pmc Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    PLoS Med 4:e263. 2007
    ..Our aim was to determine the independent associations of fasting insulin, glucose, and glycated haemoglobin with coronary heart disease and stroke in older women...
  25. pmc Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood: cross-sectional findings from the Avon Longitudinal Study of Parents and Children
    Dylan M Williams
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:1563-71. 2012
    ..Evidence of associations in children, however, is limited, and it is unknown whether associations with risk factors differ for each 25-hydroxyvitamin D analog [25-hydroxyvitamin D(2) (25[OH]D(2)) and 25-hydroxyvitamin D(2) (25[OH]D(3))]...
  26. pmc Associations of mortality with own height using son's height as an instrumental variable
    David Carslake
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, School of Social and Community Medicine, University of Bristol, United Kingdom
    Econ Hum Biol 11:351-9. 2013
    ....
  27. pmc Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Int J Epidemiol 42:97-110. 2013
    ..Details of how to access these data are provided in this cohort profile...
  28. pmc Gestational weight gain as a risk factor for hypertensive disorders of pregnancy
    Corrie Macdonald-Wallis
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, England, UK School of Social and Community Medicine, University of Bristol, Bristol, England, UK
    Am J Obstet Gynecol 209:327.e1-17. 2013
    ..Thus, we aimed to determine whether GWG in early pregnancy is a risk factor for preeclampsia and gestational hypertension and whether GWG precedes the increases in blood pressure in normotensive women across pregnancy...
  29. pmc Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol BS8 2BN, UK
    BMJ 341:c6224. 2010
    ..To examine the prospective associations between body mass index (BMI), waist circumference, and fat mass in childhood and cardiovascular risk factors at age 15-16...
  30. pmc Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood
    Abigail Fraser
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 121:2557-64. 2010
    ..We sought to examine the association of gestational weight gain (GWG) and prepregnancy weight with offspring adiposity and cardiovascular risk factors...
  31. pmc Associations of postnatal growth with asthma and atopy: the PROBIT Study
    Emma L Anderson
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Pediatr Allergy Immunol 24:122-30. 2013
    ..It has been hypothesised that postnatal weight and length/height gain are variously related to wheeze, asthma and atopy; however, supporting evidence is limited and inconsistent...
  32. pmc Associations of maternal weight gain in pregnancy with offspring cognition in childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children
    Suzanne H Gage
    Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, Bristol, United Kingdom
    Am J Epidemiol 177:402-10. 2013
    ..Findings support small positive associations between GWG and offspring cognitive development, which may have lasting effects on educational attainment up to age 16 years...
  33. pmc Cardiovascular biomarkers and vascular function during childhood in the offspring of mothers with hypertensive disorders of pregnancy: findings from the Avon Longitudinal Study of Parents and Children
    Debbie Anne Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK
    Eur Heart J 33:335-45. 2012
    ....
  34. pmc Associations of vitamin D, parathyroid hormone and calcium with cardiovascular risk factors in US adolescents
    Dylan M Williams
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Heart 97:315-20. 2011
    ..To examine independent associations of serum 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH) and calcium with a range of cardiovascular risk factors in adolescents...
  35. pmc Maternal and offspring adiposity-related genetic variants and gestational weight gain
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 94:149-55. 2011
    ..Gestational weight gain (GWG) is associated with a range of health outcomes, but little is known about the factors that influence it...
  36. pmc Childhood energy intake is associated with nonalcoholic fatty liver disease in adolescents
    Emma L Anderson
    Medical Research Council Integrative Epidemiology Unit and School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    J Nutr 145:983-9. 2015
    ..Thus, it is likely that dietary intake is involved in the development of the disease. Prospective studies assessing the relation between childhood dietary intake and risk of NAFLD are lacking...
  37. pmc Associations of blood pressure change in pregnancy with fetal growth and gestational age at delivery: findings from a prospective cohort
    Corrie Macdonald-Wallis
    From the MRC Integrative Epidemiology Unit C M W, K T, A F, D A L and School of Social and Community Medicine C M W, K T, A F, D A L, University of Bristol, Bristol, United Kingdom and School of Medicine, University of Glasgow, Glasgow, United Kingdom S M N
    Hypertension 64:36-44. 2014
    ....
  38. doi Estimating trajectories of energy intake through childhood and adolescence using linear-spline multilevel models
    Emma L Anderson
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    Epidemiology 24:507-15. 2013
    ..Methods for the assessment of changes in dietary intake across the life course are underdeveloped...
  39. pmc Association of maternal vitamin D status during pregnancy with bone-mineral content in offspring: a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol UK
    Lancet 381:2176-83. 2013
    ..Maternal vitamin D status in pregnancy is a suggested determinant of bone-mineral content (BMC) in offspring, but has been assessed in small studies. We investigated this association in a large prospective study...
  40. pmc Associations of existing diabetes, gestational diabetes, and glycosuria with offspring IQ and educational attainment: the Avon Longitudinal Study of Parents and Children
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK
    Exp Diabetes Res 2012:963735. 2012
    ..Results from studies examining associations of maternal diabetes in pregnancy with offspring cognitive outcomes have been inconclusive...
  41. pmc Blood pressure change in normotensive, gestational hypertensive, preeclamptic, and essential hypertensive pregnancies
    Corrie Macdonald-Wallis
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Hypertension 59:1241-8. 2012
    ..These distinct patterns may be useful for identifying women at risk of developing a hypertensive disorder later in pregnancy...
  42. pmc Does maternal weight gain in pregnancy have long-term effects on offspring adiposity? A sibling study in a prospective cohort of 146,894 men from 136,050 families
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 94:142-8. 2011
    ....
  43. pmc Associations of childhood 25-hydroxyvitamin D2 and D3 and cardiovascular risk factors in adolescence: prospective findings from the Avon Longitudinal Study of Parents and Children
    Dylan M Williams
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, UK
    Eur J Prev Cardiol 21:281-90. 2014
    ..We aimed to compare prospective associations of two analogues of childhood 25(OH)D (25(OH)D2 and 25(OH)D3) with cardiovascular risk factors measured in adolescence...
  44. doi Established preeclampsia risk factors are related to patterns of blood pressure change in normal term pregnancy: findings from the Avon Longitudinal Study of Parents and Children
    Corrie Macdonald-Wallis
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    J Hypertens 29:1703-11. 2011
    ..We investigated the pattern of blood pressure (BP) change across pregnancy and associations of risk factors for preeclampsia with BP changes in normal pregnancy...
  45. pmc Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children
    Gemma C Sharp
    MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK, School of Social and Community Medicine, University of Bristol, Bristol, UK and
    Int J Epidemiol 44:1288-304. 2015
    ..Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism...
  46. pmc DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework
    Rebecca C Richmond
    Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, U K School of Social and Community Medicine, University of Bristol, Bristol, U K
    Diabetes 65:1231-44. 2016
    ..Further work is required to replicate and uncover the mechanisms underlying the direct and intergenerational effect of adiposity on DNA methylation. ..
  47. pmc Weight trajectories through infancy and childhood and risk of non-alcoholic fatty liver disease in adolescence: the ALSPAC study
    Emma L Anderson
    MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK School of Social and Community Medicine, University of Bristol, Bristol, UK Electronic address
    J Hepatol 61:626-32. 2014
    ..We examined associations of weight-for-height trajectories from birth to age 10 with liver outcomes in adolescence, and assessed the extent to which associations are mediated through fat mass at the time of outcome assessment...
  48. pmc Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: a cross-sectional study of 1874 general population adolescents
    Debbie A Lawlor
    Medical Research Council Integrative Epidemiology Unit D A L, C M W, E A, A F, L D H and School of Social and Community Medicine D A L, C M W, E A, A F, L D H, University of Bristol, Bristol BS8 2BN, United Kingdom University Hospitals Bristol National Health Service Foundation Trust M C, Bristol BS1 3NU, United Kingdom Institute of Cellular Medicine C D, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom and Institute of Cardiovascular and Medical Sciences N S, BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom
    J Clin Endocrinol Metab 99:E410-7. 2014
    ..The impact of adolescent nonalcoholic fatty liver disease (NAFLD) on health, independent of fat mass, is unclear...
  49. pmc Anti-müllerian hormone is not associated with cardiometabolic risk factors in adolescent females
    Emma L Anderson
    MRC CAiTE Centre, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom
    PLoS ONE 8:e64510. 2013
    ..Existing evidence comes from small studies in select adult populations, and findings are conflicting. We aimed to assess whether AMH is associated with cardiometabolic risk factors in a general population of adolescent females...
  50. pmc Relationships of risk factors for pre-eclampsia with patterns of occurrence of isolated gestational proteinuria during normal term pregnancy
    Corrie Macdonald-Wallis
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 6:e22115. 2011
    ..Confirmation of its association with established pre-eclampsia risk factors and higher blood pressure in uncomplicated pregnancies would support this concept...
  51. pmc Cord Blood Adipokines and Lipids and Adolescent Nonalcoholic Fatty Liver Disease
    Joy Simpson
    School of Medicine J S, S M N, University of Glasgow, Glasgow G31 2ER, United Kingdom Medical Research Council Integrative Epidemiology Unit A D S, A F, D A L, School of Social and Community Medicine A D S, A F, D A L, University of Bristol, Bristol BS13NY United Kingdom Institute of Cardiovascular and Metabolic Medicine N S, R S L, British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow G61 1QH, United Kingdom and University Hospitals Bristol National Health Service Foundation Trust M C, Bristol BS1 3NY, United Kingdom
    J Clin Endocrinol Metab 101:4661-4668. 2016
    ..Recent genetic analyses suggest a causal effect of greater maternal body mass index on offspring birth weight and ponderal index, but the relative roles of the environment in utero or later in life remains unclear...
  52. pmc Antenatal blood pressure for prediction of pre-eclampsia, preterm birth, and small for gestational age babies: development and validation in two general population cohorts
    Corrie Macdonald-Wallis
    MRC Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK
    BMJ 351:h5948. 2015
    ..Can routine antenatal blood pressure measurements between 20 and 36 weeks' gestation contribute to the prediction of pre-eclampsia and its associated adverse outcomes?..
  53. pmc Gestational-age-specific reference ranges for blood pressure in pregnancy: findings from a prospective cohort
    Corrie Macdonald-Wallis
    aMRC Integrative Epidemiology Unit at the University of Bristol bSchool of Social and Community Medicine, University of Bristol, Bristol cCentre for Statistical Methodology dDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London eSchool of Medicine, University of Glasgow, Glasgow, UK
    J Hypertens 33:96-105. 2015
    ..High blood pressure in pregnancy is associated with adverse perinatal outcomes for the mother and offspring. We aimed to define normal ranges of blood pressure across gestation...
  54. pmc Rapid increases in infant adiposity and overweight/obesity in childhood are associated with higher central and brachial blood pressure in early adulthood
    Laura D Howe
    aMRC Integrative Epidemiology Unit at the University of Bristol, UK bSchool of Social and Community Medicine, University of Bristol, Bristol cNational Heart and Lung Institute, Imperial College London, London, UK
    J Hypertens 32:1789-96. 2014
    ..Aortic (central) BP differs from brachial BP and is more predictive of organ damage and cardiovascular events; the relationship between BMI in childhood and central BP is not known...
  55. doi Risk factors for variation in 25-hydroxyvitamin D₃ and D₂ concentrations and vitamin D deficiency in children
    Anna Maija Tolppanen
    Medical Research Council, Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, 15 23 Oakfield Grove, Clifton, Bristol BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:1202-10. 2012
    ..Suboptimal vitamin D status is common and associated with adverse health outcomes...
  56. pmc The association between BMI and mortality using offspring BMI as an indicator of own BMI: large intergenerational mortality study
    George Davey Smith
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, BS8 2BN
    BMJ 339:b5043. 2009
    ..To obtain valid estimates of the association between body mass index (BMI) and mortality by using offspring BMI as an instrumental variable for own BMI...
  57. doi Association of existing diabetes, gestational diabetes and glycosuria in pregnancy with macrosomia and offspring body mass index, waist and fat mass in later childhood: findings from a prospective pregnancy cohort
    D A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Diabetologia 53:89-97. 2010
    ....
  58. ncbi The association of life course socio-economic position with diagnosis, treatment, control and survival of women with diabetes: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabet Med 24:892-900. 2007
    ..To examine the association of socio-economic position (SEP) with the diagnosis, treatment and control of diabetes, and with survival in women with and without Type 2 diabetes...
  59. pmc The Prevalence of Non-Alcoholic Fatty Liver Disease in Children and Adolescents: A Systematic Review and Meta-Analysis
    Emma L Anderson
    MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 10:e0140908. 2015
    ..We aimed to estimate prevalence of non-alcoholic fatty liver disease (NAFLD) in young people and to determine whether this varies by BMI category, gender, age, diagnostic method, geographical region and study sample size...
  60. pmc Is interpregnancy interval associated with cardiovascular risk factors in later life? A cohort study
    Duleeka W Knipe
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMJ Open 4:e004173. 2014
    ..We examine the associations of short and long IPI with measures of cardiovascular health...
  61. pmc OS 04-01 EXAGGERATED EXERCISE BLOOD PRESSURE IS ASSOCIATED WITH HIGHER LEFT VENTRICULAR MASS IN ADOLESCENCE. THE AVON LONGITUDINAL STUDY OF PARENTS AND CHILDREN
    Martin Schultz
    1Department of Menzies Institute for Medical Research, University of Tasmania, Australia 2Department of Institute for Cardiovascular Sciences, University College London, United Kingdom 3Department of MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom
    J Hypertens 34:e55. 2016
    ..We determined associations of exercise BP with left ventricular mass (LVM) in adolescents, with consideration of the possible confounding effect of body composition...
  62. ncbi Intrauterine growth retardation, insulin resistance, and nonalcoholic fatty liver disease in children: response to Nobili et al
    Abigail Fraser
    Diabetes Care 30:e124; author reply e125. 2007
  63. ncbi Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosus
    Yehuda Shoenfeld
    Center for Autoimmune Diseases and Department of Medicine B, Chaim Sheba Medical Center, Tel Hashomer, Israel
    Ann N Y Acad Sci 1108:227-39. 2007
    ..These autoantibodies may play a pathogenic role in the development or perpetuation of autoimmunity in SLE...
  64. ncbi Autoantibodies in nonautoimmune individuals during infections
    Tatiana Berlin
    Department of Medicine E, Meir Hospital, Kfar Saba, Israel
    Ann N Y Acad Sci 1108:584-93. 2007
    ..In nonautoimmune individuals with various (bacterial, viral, parasitic, and rickettsial) infections, elevated titers of Abs to annexin-V, prothrombin, laminin, ASCA, ANA, and phospholipids were most frequently detected...
  65. ncbi Telomere dynamics in arteries and mononuclear cells of diabetic patients: effect of diabetes and of glycemic control
    Orit Uziel
    Laboratory for Telomere Biology, Felsenstein Medical Research Center, Rabin Medical Center, Beilinson Hospital, Sackler School of Medicine, Tel Aviv University, Israel
    Exp Gerontol 42:971-8. 2007
    ..Results of this study suggest that diabetes is associated with premature cellular senescence which can be prevented by good glycemic control in type II DM and reduced in type I DM...
  66. ncbi Benefit of appropriate empirical antibiotic treatment: thirty-day mortality and duration of hospital stay
    Abigail Fraser
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel
    Am J Med 119:970-6. 2006
    ..We evaluated the effect of inappropriate antibiotic treatment on mortality and duration of hospital stay in medical inpatients with bacterial infections...
  67. ncbi Prevalence and clinical aspects of Behcet's disease in the north of Israel
    Ilan Krause
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petach Tiqva 49100, Israel
    Clin Rheumatol 26:555-60. 2007
    ..This study confirms the high prevalence of BD in Israel and the variability in disease rates and expression by ethnic origin. Our findings, particularly regarding the Druze population, call for further field surveys and genetic studies...
  68. ncbi Prediction of bacteremia using TREAT, a computerized decision-support system
    Mical Paul
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    Clin Infect Dis 42:1274-82. 2006
    ..Prediction of bloodstream infection at the time of sepsis onset allows one to make appropriate and economical management decisions...
  69. ncbi Chlamydia pneumoniae and acute coronary syndrome
    Mical Paul
    N Engl J Med 353:525-8; author reply 525-8. 2005