Daniel Durstewitz

Summary

Affiliation: University of Plymouth
Country: UK

Publications

  1. ncbi request reprint A few important points about dopamine's role in neural network dynamics
    D Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, United Kingdom
    Pharmacopsychiatry 39:S72-5. 2006
  2. ncbi request reprint Dynamical basis of irregular spiking in NMDA-driven prefrontal cortex neurons
    Daniel Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, Plymouth, UK
    Cereb Cortex 17:894-908. 2007
  3. doi request reprint The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia
    Daniel Durstewitz
    Centre for Theoretical and Computational Neuroscience, Faculty of Science, University of Plymouth, Plymouth, United Kingdom
    Biol Psychiatry 64:739-49. 2008
  4. ncbi request reprint Computational significance of transient dynamics in cortical networks
    Daniel Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, Portland Square, Drake Circus, Plymouth PL4 8AA, UK
    Eur J Neurosci 27:217-27. 2008
  5. ncbi request reprint Beyond bistability: biophysics and temporal dynamics of working memory
    D Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, A 220 Portland Square, Drake Circus, Plymouth PL4 8AA, UK
    Neuroscience 139:119-33. 2006
  6. ncbi request reprint The ability of the mesocortical dopamine system to operate in distinct temporal modes
    Christopher C Lapish
    Department of Neurosciences, Medical University of South Carolina, Suite 430 BSB 173 Ashley, Charleston, SC, USA
    Psychopharmacology (Berl) 191:609-25. 2007
  7. pmc Successful choice behavior is associated with distinct and coherent network states in anterior cingulate cortex
    Christopher C Lapish
    Department of Psychiatry and Brain Research Centre, University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC, V6T 2B5
    Proc Natl Acad Sci U S A 105:11963-8. 2008
  8. ncbi request reprint Self-organizing neural integrator predicts interval times through climbing activity
    Daniel Durstewitz
    Department of Biopsychology, Ruhr University Bochum, D 44780 Bochum, Germany
    J Neurosci 23:5342-53. 2003
  9. ncbi request reprint Neural representation of interval time
    Daniel Durstewitz
    Institute for Cognitive Neuroscience, GAFO 04 991, Ruhr University Bochum, D 44780 Bochum, Germany
    Neuroreport 15:745-9. 2004
  10. ncbi request reprint The computational role of dopamine D1 receptors in working memory
    Daniel Durstewitz
    AE Biopsychologie, Facultät für Psychologie, Ruhr Universitat Bochum, Germany
    Neural Netw 15:561-72. 2002

Detail Information

Publications10

  1. ncbi request reprint A few important points about dopamine's role in neural network dynamics
    D Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, United Kingdom
    Pharmacopsychiatry 39:S72-5. 2006
    ..These properties could be crucial for understanding dopamine's functional role...
  2. ncbi request reprint Dynamical basis of irregular spiking in NMDA-driven prefrontal cortex neurons
    Daniel Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, Plymouth, UK
    Cereb Cortex 17:894-908. 2007
    ..The nonlinearity of NMDA conductances was crucial for inducing this regime. NMDA-induced irregular dynamics may have important implications for computational processes during working memory and neural coding...
  3. doi request reprint The dual-state theory of prefrontal cortex dopamine function with relevance to catechol-o-methyltransferase genotypes and schizophrenia
    Daniel Durstewitz
    Centre for Theoretical and Computational Neuroscience, Faculty of Science, University of Plymouth, Plymouth, United Kingdom
    Biol Psychiatry 64:739-49. 2008
    ....
  4. ncbi request reprint Computational significance of transient dynamics in cortical networks
    Daniel Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, Portland Square, Drake Circus, Plymouth PL4 8AA, UK
    Eur J Neurosci 27:217-27. 2008
    ..Neural computation has to exploit the itinerant dynamics between these states...
  5. ncbi request reprint Beyond bistability: biophysics and temporal dynamics of working memory
    D Durstewitz
    Centre for Theoretical and Computational Neuroscience, University of Plymouth, A 220 Portland Square, Drake Circus, Plymouth PL4 8AA, UK
    Neuroscience 139:119-33. 2006
    ..Together such findings may lay the foundations for highly dynamical theories of working memory based on biophysical principles...
  6. ncbi request reprint The ability of the mesocortical dopamine system to operate in distinct temporal modes
    Christopher C Lapish
    Department of Neurosciences, Medical University of South Carolina, Suite 430 BSB 173 Ashley, Charleston, SC, USA
    Psychopharmacology (Berl) 191:609-25. 2007
    ..This review discusses evidence that cells in the mesocortical dopamine (DA) system influence information processing in target areas across three distinct temporal domains...
  7. pmc Successful choice behavior is associated with distinct and coherent network states in anterior cingulate cortex
    Christopher C Lapish
    Department of Psychiatry and Brain Research Centre, University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC, V6T 2B5
    Proc Natl Acad Sci U S A 105:11963-8. 2008
    ..These results point to an underlying functional organization into cell assemblies in the ACC that may monitor choices, outcomes, and task contexts, thus tracking the animal's progression through "task space."..
  8. ncbi request reprint Self-organizing neural integrator predicts interval times through climbing activity
    Daniel Durstewitz
    Department of Biopsychology, Ruhr University Bochum, D 44780 Bochum, Germany
    J Neurosci 23:5342-53. 2003
    ..Thus, specific mechanisms are proposed for (1) how neurons might represent interval times of variable length and (2) how neurons could acquire the biophysical properties that enable them to work as timers...
  9. ncbi request reprint Neural representation of interval time
    Daniel Durstewitz
    Institute for Cognitive Neuroscience, GAFO 04 991, Ruhr University Bochum, D 44780 Bochum, Germany
    Neuroreport 15:745-9. 2004
    ..Various neural mechanisms for producing climbing activity with variable slopes, representing the length of learned intervals, are discussed...
  10. ncbi request reprint The computational role of dopamine D1 receptors in working memory
    Daniel Durstewitz
    AE Biopsychologie, Facultät für Psychologie, Ruhr Universitat Bochum, Germany
    Neural Netw 15:561-72. 2002
    ..In this manner, D1 receptor stimulation might regulate the extent to which PFC network activity is focused on a particular goal state versus being open to new goals or information unrelated to the current goal...