Michael Doherty

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms
    M Hall
    Academic Rheumatology, University of Nottingham, UK School of Health Sciences, University of Nottingham, UK Electronic address
    Osteoarthritis Cartilage 22:1627-33. 2014
  2. pmc Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial
    Sarah R Kingsbury
    Division of Rheumatic and Musculoskeletal Disease and National Institute of Health Research NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds LS7 4SA, UK
    Trials 14:64. 2013
  3. pmc Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review
    Marienke van Middelkoop
    Department of General Practice, Erasmus MC Medical University, PO Box 2040, 3000, CA, Rotterdam, The Netherlands
    Syst Rev 2:54. 2013
  4. doi Gout: why is this curable disease so seldom cured?
    Michael Doherty
    Department of Rheumatology, City Hospital, Nottingham, UK
    Ann Rheum Dis 71:1765-70. 2012
  5. pmc Do estimates of cost-utility based on the EQ-5D differ from those based on the mapping of utility scores?
    Garry R Barton
    Health Economics Group, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Health Qual Life Outcomes 6:51. 2008
  6. pmc Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee pain
    Garry R Barton
    Health Economics Group, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Cost Eff Resour Alloc 7:12. 2009
  7. pmc Epidemiology of gout
    Edward Roddy
    Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire ST5 5BG, UK
    Arthritis Res Ther 12:223. 2010
  8. doi The "placebo" response in osteoarthritis and its implications for clinical practice
    M Doherty
    University of Nottingham, Nottingham, UK
    Osteoarthritis Cartilage 17:1255-62. 2009
  9. ncbi Epidemiology and genetics of hand osteoarthritis
    M Doherty
    Academic Rheumatology, City Hospital, Nottingham, UK
    Osteoarthritis Cartilage 8:S14-5. 2000
  10. doi A randomised controlled trial of ibuprofen, paracetamol or a combination tablet of ibuprofen/paracetamol in community-derived people with knee pain
    Michael Doherty
    Arthritis Research UK Pain Centre, Academic Rheumatology, Nottingham City Hospital, UK
    Ann Rheum Dis 70:1534-41. 2011

Detail Information

Publications145 found, 100 shown here

  1. pmc Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms
    M Hall
    Academic Rheumatology, University of Nottingham, UK School of Health Sciences, University of Nottingham, UK Electronic address
    Osteoarthritis Cartilage 22:1627-33. 2014
    ....
  2. pmc Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial
    Sarah R Kingsbury
    Division of Rheumatic and Musculoskeletal Disease and National Institute of Health Research NIHR Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds LS7 4SA, UK
    Trials 14:64. 2013
    ..We propose that treating patients with symptomatic hand OA with hydroxychloroquine will be a practical and safe treatment to reduce synovitis and pain...
  3. pmc Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis: an OA Trial Bank protocol for a systematic review
    Marienke van Middelkoop
    Department of General Practice, Erasmus MC Medical University, PO Box 2040, 3000, CA, Rotterdam, The Netherlands
    Syst Rev 2:54. 2013
    ....
  4. doi Gout: why is this curable disease so seldom cured?
    Michael Doherty
    Department of Rheumatology, City Hospital, Nottingham, UK
    Ann Rheum Dis 71:1765-70. 2012
    ....
  5. pmc Do estimates of cost-utility based on the EQ-5D differ from those based on the mapping of utility scores?
    Garry R Barton
    Health Economics Group, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Health Qual Life Outcomes 6:51. 2008
    ..We sought to compare the QALY gains, and incremental cost per QALY estimates, predicted on the basis of mapping to those based on actual EQ-5D scores...
  6. pmc Comparing the performance of the EQ-5D and SF-6D when measuring the benefits of alleviating knee pain
    Garry R Barton
    Health Economics Group, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
    Cost Eff Resour Alloc 7:12. 2009
    ..This suggests that it is more appropriate to use the EQ-5D in future cost-effectiveness analyses of interventions which are designed to alleviate knee pain. TRIAL REGISTRATION: Current Controlled Trials ISRCTN93206785...
  7. pmc Epidemiology of gout
    Edward Roddy
    Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire ST5 5BG, UK
    Arthritis Res Ther 12:223. 2010
    ..Gout appears to be an independent risk factor for all-cause mortality and cardiovascular mortality and morbidity, additional to the risk conferred by its association with traditional cardiovascular risk factors...
  8. doi The "placebo" response in osteoarthritis and its implications for clinical practice
    M Doherty
    University of Nottingham, Nottingham, UK
    Osteoarthritis Cartilage 17:1255-62. 2009
    ....
  9. ncbi Epidemiology and genetics of hand osteoarthritis
    M Doherty
    Academic Rheumatology, City Hospital, Nottingham, UK
    Osteoarthritis Cartilage 8:S14-5. 2000
    ..The following important factors were discussed: Genetics, Age, Gender, Obesity, HRT (hormone replacement therapy), Physical activity/trauma...
  10. doi A randomised controlled trial of ibuprofen, paracetamol or a combination tablet of ibuprofen/paracetamol in community-derived people with knee pain
    Michael Doherty
    Arthritis Research UK Pain Centre, Academic Rheumatology, Nottingham City Hospital, UK
    Ann Rheum Dis 70:1534-41. 2011
    ..To compare the efficacy and safety of single versus combination non-prescription oral analgesics in community-derived people aged 40 years and older with chronic knee pain...
  11. doi Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: a case-control study
    Michael Doherty
    University of Nottingham, Nottingham University Hospitals Trust, Nottingham, UK
    Arthritis Rheum 58:3172-82. 2008
    ..To determine whether 2-dimensional measures of femoral head shape and angle are associated with hip osteoarthritis (OA)...
  12. ncbi Genetics of hand osteoarthritis
    M Doherty
    Academic Rheumatology, City Hospital, Nottingham, UK
    Osteoarthritis Cartilage 8:S8-10. 2000
    ..Such ongoing work and subsequent gene-gene and gene-environment interaction studies are likely to give important, perhaps unexpected, insights into the pathogenesis of hand OA...
  13. pmc UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte
    R L Neame
    Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 62:513-8. 2003
    ..2) To investigate the associations between CC and individual radiographic features of osteoarthritis (OA) at the tibiofemoral joint (TFJ) and patellofemoral joint (PFJ)...
  14. doi New insights into the epidemiology of gout
    Michael Doherty
    Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Rheumatology (Oxford) 48:ii2-ii8. 2009
    ..New knowledge of the modifiable risk factors for gout can be integrated into the management strategy to optimize long-term patient outcomes...
  15. doi Self-reported knee malalignment in early adult life as an independent risk for knee chondrocalcinosis
    Abhishek Abhishek
    University of Nottingham, UK
    Arthritis Care Res (Hoboken) 63:1550-7. 2011
    ..To determine if self-reported current and early adult life knee malalignment is associated with knee chondrocalcinosis (CC)...
  16. doi Self-reported knee and foot alignments in early adult life and risk of osteoarthritis
    Daniel F McWilliams
    Academic Rheumatology, Clinical Sciences Building, University of Nottingham, City Hospital, Nottingham, UK
    Arthritis Care Res (Hoboken) 62:489-95. 2010
    ..To determine whether self-reported early adult life malalignment of knees or feet are risk factors for knee or hip osteoarthritis (OA)...
  17. ncbi An assessment of the discriminative ability of the EQ-5Dindex, SF-6D, and EQ VAS, using sociodemographic factors and clinical conditions
    Garry R Barton
    School of Economics, University of Nottingham, Nottingham, NG7 2UH, UK
    Eur J Health Econ 9:237-49. 2008
    ..To assess whether three health-related quality-of-life (HRQL) measures (the EQ-5Dindex, SF-6D, and EQ VAS) can discriminate between the HRQL of different groups of individuals...
  18. pmc Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendations
    Edward Roddy
    Academic Rheumatology, University of Nottingham, UK
    Ann Rheum Dis 66:1311-5. 2007
    ..To assess concordance of the management of chronic gout in UK primary care with the European League Against Rheumatism (EULAR) gout recommendations...
  19. doi Distribution of finger nodes and their association with underlying radiographic features of osteoarthritis
    Frances Rees
    University of Nottingham, Nottingham, UK
    Arthritis Care Res (Hoboken) 64:533-8. 2012
    ....
  20. ncbi Distribution of radiographic osteoarthritis between the right and left hands, hips, and knees
    Rebecca Neame
    Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Nottingham NG5 1PB, UK
    Arthritis Rheum 50:1487-94. 2004
    ..To investigate whether radiographic osteoarthritis (OA) is asymmetric and greater on the right side than on the left side in the hands, hips, and knees...
  21. ncbi Evidence-based clinical guidelines: a new system to better determine true strength of recommendation
    Edward Roddy
    Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, UK
    J Eval Clin Pract 12:347-52. 2006
    ..The purpose of this study was to develop a new method of determining SOR, incorporating both research evidence and expert opinion...
  22. doi Nottingham knee osteoarthritis risk prediction models
    Weiya Zhang
    Academic Rheumatology, University of Nottingham, Nottingham, UK
    Ann Rheum Dis 70:1599-604. 2011
    ..1) To develop risk prediction models for knee osteoarthritis (OA) and (2) to estimate the risk reduction that results from modification of potential risk factors...
  23. doi Prevalence and associations of hallux valgus in a primary care population
    Edward Roddy
    University of Nottingham, Nottingham, UK
    Arthritis Rheum 59:857-62. 2008
    ..To determine the population prevalence and examine factors associated with hallux valgus in a primary care population...
  24. pmc Are joints affected by gout also affected by osteoarthritis?
    Edward Roddy
    Academic Rheumatology, University of Nottingham, UK
    Ann Rheum Dis 66:1374-7. 2007
    ..To determine whether joints affected by gout are also affected by osteoarthritis (OA)...
  25. pmc Effect of pain reduction on postural sway, proprioception, and quadriceps strength in subjects with knee osteoarthritis
    B S Hassan
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK
    Ann Rheum Dis 61:422-8. 2002
    ..To investigate whether alleviation of knee pain influences quadriceps function, proprioceptive acuity, and postural stability in patients with knee osteoarthritis (OA)...
  26. doi Familial Aggregation of Systemic Lupus Erythematosus and Coaggregation of Autoimmune Diseases in Affected Families
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics, and Dermatology, School of Medicine, University of Nottingham, Nottingham, England2Division of Rheumatology, Allergy, and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    JAMA Intern Med 175:1518-26. 2015
    ..Furthermore, relative contributions of genetic, shared, and unshared environmental factors to SLE susceptibility remain unclear...
  27. pmc Familial Risk of Sjögren's Syndrome and Co-aggregation of Autoimmune Diseases in Affected Families: A Nationwide Population Study
    Chang Fu Kuo
    University of Nottingham, Nottingham, UK, and Chang Gung Memorial Hospital, Taoyuan City, Taiwan
    Arthritis Rheumatol 67:1904-12. 2015
    ..To investigate familial aggregation of Sjögren's syndrome (SS) and the relative risks (RRs) of other autoimmune disease in relatives of patients with SS...
  28. pmc The genetic contribution to severe post-traumatic osteoarthritis
    Ana M Valdes
    Academic Rheumatology, Nottingham City Hospital, Nottingham, UK
    Ann Rheum Dis 72:1687-90. 2013
    ..to compare the combined role of genetic variants loci associated with risk of knee or hip osteoarthritis (OA) in post-traumatic (PT) and non-traumatic (NT) cases of clinically severe OA leading to total joint replacement...
  29. doi Does smoking reduce the progression of osteoarthritis? Meta-analysis of observational studies
    Fiona Pearce
    University of Nottingham, Nottingham, UK
    Arthritis Care Res (Hoboken) 65:1026-33. 2013
    ..To determine whether smoking reduces the progression of osteoarthritis (OA)...
  30. doi Joint aspiration and injection and synovial fluid analysis
    Philip Courtney
    Department of Rheumatology, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
    Best Pract Res Clin Rheumatol 27:137-69. 2013
    ..However, detection of SF monosodium urate and calcium pyrophosphate dihydrate crystals, even from un-inflamed joints during intercritical periods, allows a precise diagnosis of gout and calcium pyrophosphate crystal-related arthritis...
  31. doi Mild acetabular dysplasia and risk of osteoarthritis of the hip: a case-control study
    Daniel F McWilliams
    Academic Rheumatology, University of Nottingham, Nottingham, UK
    Ann Rheum Dis 69:1774-8. 2010
    ..To determine whether mild variation in acetabular depth (AD) and shape is a risk factor for osteoarthritis (OA) of the hip...
  32. doi Intercritical circulating levels of neo-epitopes reflecting matrixmetalloprotease-driven degradation as markers of gout and frequent gout attacks
    Ana M Valdes
    Academic Rheumatology, Clinical Sciences Building, University of Nottingham, Nottingham City Hospital, Nottingham, UK
    Rheumatology (Oxford) 55:1642-6. 2016
    ..Recurrent flares constitute the main clinical burden of gout. Our aim was to assess whether biomarkers measuring MMP tissue degradation could be used as markers of frequent gout flares...
  33. pmc Epidemiology and management of gout in Taiwan: a nationwide population study
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, UK
    Arthritis Res Ther 17:13. 2015
    ..The aim of this study was to describe trends in the epidemiology of gout in the general population of Taiwan...
  34. doi Joint aspiration and injection and synovial fluid analysis
    Philip Courtney
    Nottingham City Hospital, Nottingham, UK
    Best Pract Res Clin Rheumatol 23:161-92. 2009
    ..However, detection of SF monosodium urate and calcium pyrophosphate dihydrate crystals, even from un-inflamed joints during intercritical periods, allow a precise diagnosis of gout and of calcium pyrophosphate crystal-related arthritis...
  35. pmc EULAR evidence based recommendations for the management of hip osteoarthritis: report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    W Zhang
    Academic Rheumatology, University of Nottingham, UK
    Ann Rheum Dis 64:669-81. 2005
    ..To develop evidence based recommendations for the management of hip osteoarthritis (OA)...
  36. pmc Genetic risk of knee osteoarthritis: a sibling study
    R L Neame
    Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK
    Ann Rheum Dis 63:1022-7. 2004
    ..To determine whether there is a genetic contribution to knee osteoarthritis (OA) as defined by structural change on plain radiographs...
  37. ncbi Familial Aggregation and Heritability of Schizophrenia and Co-aggregation of Psychiatric Illnesses in Affected Families
    I Jun Chou
    Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham, UK
    Schizophr Bull . 2016
    ..Heritability and environmental factors each account for half of the phenotypic variance of schizophrenia...
  38. doi Early clinical features in Systemic Lupus Erythematosus: can they be used to achieve earlier diagnosis? A risk prediction model
    Frances Rees
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Clinical Sciences Building, City Hospital Nottingham, NG5 1PB, UK
    Arthritis Care Res (Hoboken) . 2016
    ..1) To compare the primary care consulting behaviour prior to diagnosis of people with Systemic Lupus Erythematosus (SLE) with controls, 2) to develop and validate a risk prediction model to aid earlier SLE diagnosis...
  39. doi Beta-blocker use associates with lower prevalence of joint pain and lower opioid requirement in people with osteoarthritis
    Ana M Valdes
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, Nottingham, NG5 1PB, UK
    Arthritis Care Res (Hoboken) . 2016
    ..Analyses were adjusted for age, gender, BMI, knee or hip OA, history of joint replacement (at other joints), anxiety and depression...
  40. doi Burden of Comorbidity in Systemic Lupus Erythematosus in the UK, 1999-2012
    Frances Rees
    University of Nottingham and Nottingham University Hospitals NHS Trust, Nottingham, UK
    Arthritis Care Res (Hoboken) 68:819-27. 2016
    ..To estimate the comorbidity associated with systemic lupus erythematosus (SLE) in the UK during 1999-2012...
  41. pmc Familial risk of systemic sclerosis and co-aggregation of autoimmune diseases in affected families
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, NG51PD, Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham, NG51PB, Nottingham, UK
    Arthritis Res Ther 18:231. 2016
    ..Systemic sclerosis (SSc) is a rare and devastating disease affecting skin and internal organs. Familial aggregation of SSc and co-aggregation with other autoimmune diseases is rarely reported...
  42. pmc Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study
    Daniel F McWilliams
    Division of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Nottingham, UK
    BMC Musculoskelet Disord 15:308. 2014
    ..Our underlying hypotheses were that high heeled, narrow heeled, and hard soled shoe types were putative risk factors for lower limb OA...
  43. doi Rheumatoid arthritis is getting less frequent-results of a nationwide population-based cohort study
    Abhishek Abhishek
    Academic Rheumatology, School of Medicine, Clinical Sciences Building, City Hospital Nottingham, Nottingham
    Rheumatology (Oxford) . 2017
    ..The objectives of this study were to examine changes in the incidence and prevalence of RA between 1990 and 2014 and to explore if there is any geographic variation in the incidence and prevalence of RA in the UK...
  44. pmc Relative efficacy of different types of exercise for treatment of knee and hip osteoarthritis: protocol for network meta-analysis of randomised controlled trials
    Siew Li Goh
    Academic Rheumatology, Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK
    Syst Rev 5:147. 2016
    ..The aim of this study is to benchmark different types of exercises against each other through the use of a common comparator in a network meta-analysis of randomised controlled trials (RCTs)...
  45. doi Impact of gout on the risk of atrial fibrillation
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK, Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Rheumatology (Oxford) 55:721-8. 2016
    ..To examine the risk of atrial fibrillation (AF) at the time of first diagnosis of gout compared with matched controls and to follow incident gout patients and their matched controls after diagnosis to compare their subsequent risk of AF...
  46. pmc Comorbidities in patients with gout prior to and following diagnosis: case-control study
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Ann Rheum Dis 75:210-7. 2016
    ..To determine the burden of comorbidities in patients with gout at diagnosis and the risk of developing new comorbidities post diagnosis...
  47. doi Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score-matched landmark analysis
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK, Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Rheumatology (Oxford) 54:2145-50. 2015
    ..To examine the association between allopurinol use and all-cause mortality for patients with incident gout...
  48. pmc Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study
    Stella G Muthuri
    Division of Epidemiology and Public Health, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, Nottingham, NG5 1PB, UK
    Arthritis Res Ther 17:23. 2015
    ..The aim of this study was to investigate the association between alcoholic and non-alcoholic beverages and knee or hip osteoarthritis (OA)...
  49. doi Diagnosis and clinical presentation of osteoarthritis
    A Abhishek
    Academic Rheumatology, University of Nottingham, Nottingham, UK
    Rheum Dis Clin North Am 39:45-66. 2013
    ..The diagnosis of OA may be made without recourse to radiographic or laboratory investigations in the at-risk age group with typical symptoms and signs...
  50. doi Pathophysiology of articular chondrocalcinosis--role of ANKH
    Abhishek Abhishek
    Division of Academic Rheumatology, Clinical Sciences Building, City Hospital Nottingham, Hucknall Road, Nottingham NG51PB, UK
    Nat Rev Rheumatol 7:96-104. 2011
    ..Cartilage factors predisposing to CPPD and CPP-crystal-induced inflammation and current treatment options for the management of CPPD are also described...
  51. pmc Effects of dietary intervention and quadriceps strengthening exercises on pain and function in overweight people with knee pain: randomised controlled trial
    Claire M Jenkinson
    Division of Epidemiology and Public Health, School of Community Health Sciences, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH
    BMJ 339:b3170. 2009
    ..To determine whether dietary intervention or knee strengthening exercise, or both, can reduce knee pain and improve knee function in overweight and obese adults in the community...
  52. doi European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 70:563-70. 2011
    ..To agree terminology and to develop recommendations for the diagnosis of calcium pyrophosphate deposition (CPPD)...
  53. doi EULAR recommendations for calcium pyrophosphate deposition. Part II: management
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 70:571-5. 2011
    ..To develop evidence-based recommendations for management of calcium pyrophosphate deposition (CPPD)...
  54. doi OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009
    W Zhang
    Nottingham City Hospital, University of Nottingham, Nottingham, UK
    Osteoarthritis Cartilage 18:476-99. 2010
    ..To update evidence for available therapies in the treatment of hip and knee osteoarthritis (OA) and to examine whether research evidence has changed from 31 January 2006 to 31 January 2009...
  55. ncbi Is gout associated with reduced quality of life? A case-control study
    E Roddy
    Academic Rheumatology, University of Nottingham, UK
    Rheumatology (Oxford) 46:1441-4. 2007
    ..To compare quality of life (QOL) between gout cases and controls in a primary care population and to investigate whether impaired QOL in gout is secondary to co-morbid factors or to intrinsic factors related to gout itself...
  56. doi EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis
    W Zhang
    Academic Rheumatology, University of Nottingham, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 69:483-9. 2010
    ..To develop evidence-based recommendations for the diagnosis of knee osteoarthritis (OA)...
  57. pmc Beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis
    D P Tonge
    Nutritional Sciences, School of Biosciences, Sutton Bonington Campus, Sutton Bonington, University of Nottingham, LE12 5RD, UK
    Osteoarthritis Cartilage 18:555-62. 2010
    ..To examine whether beta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle can modulate the severity of osteoarthritis (OA) in the rodent meniscectomy (MNX) model...
  58. doi Index to ring finger length ratio and the risk of osteoarthritis
    W Zhang
    University of Nottingham, Nottingham, UK
    Arthritis Rheum 58:137-44. 2008
    ..To determine the relationship between the index to ring finger (2D:4D) length ratio and the risk of knee and hip osteoarthritis (OA)...
  59. doi EULAR evidence-based recommendations for the diagnosis of hand osteoarthritis: report of a task force of ESCISIT
    W Zhang
    Dr W Zhang, Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 68:8-17. 2009
    ..To develop evidence-based recommendations for the diagnosis of hand osteoarthritis (OA)...
  60. doi The placebo effect and its determinants in osteoarthritis: meta-analysis of randomised controlled trials
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 67:1716-23. 2008
    ....
  61. pmc EULAR evidence based recommendations for the management of hand osteoarthritis: report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 66:377-88. 2007
    ..To develop evidence based recommendations for the management of hand osteoarthritis (OA)...
  62. pmc Relative impact of radiographic osteoarthritis and pain on quadriceps strength, proprioception, static postural sway and lower limb function
    M C Hall
    Division of Physiotherapy Education, University of Nottingham, Clinical Sciences Building, Hucknall Rd, Nottingham NG5 1PB, UK
    Ann Rheum Dis 65:865-70. 2006
    ..To investigate the relative impact of radiographic osteoarthritis (ROA) and current knee pain on lower limb physical function, quadriceps strength, knee joint proprioception, and postural sway...
  63. ncbi Cost effectiveness of a two-year home exercise program for the treatment of knee pain
    K S Thomas
    City Hospital, Nottingham, United Kingdom
    Arthritis Rheum 53:388-94. 2005
    ..To assess the cost effectiveness of a 2-year home exercise program for the treatment of knee pain...
  64. ncbi Evidence-based recommendations for the role of exercise in the management of osteoarthritis of the hip or knee--the MOVE consensus
    E Roddy
    Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
    Rheumatology (Oxford) 44:67-73. 2005
    ..Many unanswered questions remain, however, concerning the practical delivery of exercise therapy. We have produced evidence-based recommendations to guide health-care practitioners...
  65. pmc Relative risk of knee chondrocalcinosis in siblings of index cases with pyrophosphate arthropathy
    W Zhang
    Academic Rheumatology, University of Nottingham, Nottingham, UK
    Ann Rheum Dis 63:969-73. 2004
    ..To examine the genetic contribution to common, apparently sporadic, radiographic knee chondrocalcinosis (CC) and pyrophosphate arthropathy (PA)...
  66. pmc Influence of radiographic phenotype on risk of hip osteoarthritis within families
    P Lanyon
    Department of Rheumatology, Queens Medical Centre, Nottingham, NG7 2UH, UK
    Ann Rheum Dis 63:259-63. 2004
    ..To determine whether the magnitude of the genetic influence on the development of hip osteoarthritis (OA) varies according to the radiographic phenotype within families...
  67. pmc Aerobic walking or strengthening exercise for osteoarthritis of the knee? A systematic review
    E Roddy
    Academic Rheumatology, Nottingham City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 64:544-8. 2005
    ..To compare the efficacy of aerobic walking and home based quadriceps strengthening exercises in patients with knee osteoarthritis...
  68. pmc Influence of elastic bandage on knee pain, proprioception, and postural sway in subjects with knee osteoarthritis
    B S Hassan
    Academic Rheumatology, Clinical Sciences Building, University of Nottingham, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
    Ann Rheum Dis 61:24-8. 2002
    ....
  69. ncbi The relationship between body mass index and health-related quality of life: comparing the EQ-5D, EuroQol VAS and SF-6D
    T H Sach
    School of Community Health Sciences, University of Nottingham, Nottingham, UK
    Int J Obes (Lond) 31:189-96. 2007
    ..Estimating the HRQL effects of obesity on a (common) utility scale enables the relative cost-effectiveness of interventions designed to alleviate obesity to be estimated...
  70. pmc Does paracetamol (acetaminophen) reduce the pain of osteoarthritis? A meta-analysis of randomised controlled trials
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 63:901-7. 2004
    ..To assess the best available evidence for efficacy of paracetamol (acetaminophen) in the treatment of osteoarthritis (OA)...
  71. ncbi Evidence-based management of osteoarthritis: practical issues relating to the data
    M Doherty
    Academic Rheumatology, Clinical Science Buildings, City Hospital, Nottingham, NG5 1PB, UK
    Best Pract Res Clin Rheumatol 15:517-25. 2001
    ..The restricted generalizability of the research data could be improved by improvements in study design and methods of reporting. Current published guidelines on management of OA are critically reviewed and compared...
  72. ncbi Ibuprofen versus other non-steroidal anti-inflammatory drugs: use in general practice and patient perception
    J M Seager
    Division of Gastroenterology, University Hospital, Nottingham, UK
    Aliment Pharmacol Ther 14:187-91. 2000
    ..To investigate whether ibuprofen was as well-regarded by patients as other non-steroidal anti-inflammatory drugs (NSAIDs)...
  73. pmc Key questions concerning paracetamol and NSAIDs for osteoarthritis
    P Courtney
    Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 61:767-73. 2002
  74. pmc EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 65:1312-24. 2006
    ..To develop evidence based recommendations for the management of gout...
  75. pmc EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT)
    W Zhang
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 65:1301-11. 2006
    ..To develop evidence based recommendations for the diagnosis of gout...
  76. ncbi Pharmacoepidemiology of non-steroidal anti-inflammatory drug use in Nottingham general practices
    D J Cullen
    Division of Gastroenterology, University Hospital, Nottingham, UK
    Aliment Pharmacol Ther 14:177-85. 2000
    ..To investigate the pharmacoepidemiology of NSAID usage in Nottingham general practices...
  77. doi Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene
    Sophie C Warner
    Academic Rheumatology, Clinical Sciences Building, University of Nottingham, Nottingham City Hospital, Nottingham, UK
    Eur J Hum Genet . 2017
    ..European Journal of Human Genetics advance online publication, 4 January 2017; doi:10.1038/ejhg.2016.196...
  78. doi Association of Serum Uric Acid and Disease Duration With Frequent Gout Attacks: A Case-Control Study
    Abhishek Abhishek
    University of Nottingham, Nottingham, UK
    Arthritis Care Res (Hoboken) 68:1573-7. 2016
    ..To ascertain whether readily available disease and demographic factors associate with frequent acute attacks of gout, and to find out whether they can identify patients especially at risk of recurrent gout attacks...
  79. doi Erosive and osteoarthritic structural progression in early rheumatoid arthritis
    Daniel F McWilliams
    Arthritis Research UK Pain Centre, Division of ROD Division of ROD, University of Nottingham, UK
    Rheumatology (Oxford) 55:1477-88. 2016
    ..To investigate factors associated with joint damage in early RA, and how comorbid OA might influence patient assessment and outcomes...
  80. pmc The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012
    Frances Rees
    Division of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Nottingham, UK Rheumatology Department, Nottingham University Hospitals NHS Trust, Nottingham, UK
    Ann Rheum Dis 75:136-41. 2016
    ..To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999-2012...
  81. doi Use of prescription analgesic medication and pain catastrophizing after total joint replacement surgery
    Ana M Valdes
    Academic Rheumatology, Nottingham City Hospital, Clinical Sciences Building, Hucknall Rd, Nottingham NG5 1PB, UK Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, UK Electronic address
    Semin Arthritis Rheum 45:150-5. 2015
    ..To survey the use of analgesic medication 4.8 years after total joint replacement (TJR) surgery and assess the determinants of medication usage...
  82. pmc Rising burden of gout in the UK but continuing suboptimal management: a nationwide population study
    Chang Fu Kuo
    Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Ann Rheum Dis 74:661-7. 2015
    ..To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012...
  83. doi History of knee surgery is associated with higher prevalence of neuropathic pain-like symptoms in patients with severe osteoarthritis of the knee
    Ana M Valdes
    Academic Rheumatology, Clinical Sciences Building, Nottingham City Hospital Hucknall Road, Nottingham NG5 1PB, UK Electronic address
    Semin Arthritis Rheum 43:588-92. 2014
    ..Neuropathic pain (NP) mechanisms contribute to the pain experience in osteoarthritis (OA). We aimed to characterise the factors that contribute to NP-like symptoms in knee OA patients...
  84. ncbi Changing life-styles and osteoarthritis: what is the evidence?
    Edward Roddy
    Academic Rheumatology, Clinical Sciences Building, Hucknall Road, Nottingham NG5 1PB, UK
    Best Pract Res Clin Rheumatol 20:81-97. 2006
    ..Our discussion focuses predominantly on knee OA, to which most of the evidence relates but refers to other sites where appropriate...
  85. ncbi A comparison of the performance of the EQ-5D and SF-6D for individuals aged >or= 45 years
    Garry R Barton
    School of Economics, University of Nottingham, Nottingham, UK
    Health Econ 17:815-32. 2008
    ..001), whereas less healthy individuals had higher mean scores on the SF-6D (individuals with knee pain, osteoarthritis, back pain, rheumatoid arthritis, and hip pain had significantly lower mean scores on the EQ-5D, p<0.001)...
  86. doi What if we prevent obesity? Risk reduction in knee osteoarthritis estimated through a meta-analysis of observational studies
    Stella G Muthuri
    University of Nottingham, Nottingham, UK
    Arthritis Care Res (Hoboken) 63:982-90. 2011
    ..To summarize the overall relative risk of knee osteoarthritis (OA) associated with body mass index, and to estimate the potential risk reduction due to the control of this risk factor...
  87. pmc Efficacy of topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: meta-analysis of randomised controlled trials
    Jinying Lin
    Academic Rheumatology, University of Nottingham, City Hospital, Nottingham NG5 1PB
    BMJ 329:324. 2004
    ..To assess the efficacy of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis...
  88. ncbi A nurse-delivered advice intervention can reduce chronic non-steroidal anti-inflammatory drug use in general practice: a randomized controlled trial
    A C Jones
    Division of Public Health Medicine and Epidemiology, Nottingham University, Nottingham, NG5 1PB, UK
    Rheumatology (Oxford) 41:14-21. 2002
    ..To find out whether a nurse-delivered educational package can reduce chronic oral non-steroidal anti-inflammatory drug (NSAID) usage in general practice...
  89. pmc Static postural sway, proprioception, and maximal voluntary quadriceps contraction in patients with knee osteoarthritis and normal control subjects
    B S Hassan
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK
    Ann Rheum Dis 60:612-8. 2001
    ..Pain and muscle strength may particularly influence postural sway. The interaction between physiological, structural, and functional abnormalities in knee OA deserves further study...
  90. pmc Home based exercise programme for knee pain and knee osteoarthritis: randomised controlled trial
    K S Thomas
    Academic Rheumatology, City Hospital, Nottingham NG5 1PB
    BMJ 325:752. 2002
    ..To determine whether a home based exercise programme can improve outcomes in patients with knee pain...
  91. doi Long-term persistence and adherence on urate-lowering treatment can be maintained in primary care-5-year follow-up of a proof-of-concept study
    Abhishek Abhishek
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital
    Rheumatology (Oxford) . 2017
    ..To evaluate the persistence and adherence on urate-lowering treatment (ULT) in primary care 5 years after an initial nurse-led treatment of gout...
  92. pmc Prevalence, risk factors and associations of primary Raynaud's phenomenon: systematic review and meta-analysis of observational studies
    Rozeena Garner
    Department of Rheumatology, Queens Medical Centre, Nottingham, UK
    BMJ Open 5:e006389. 2015
    ..To systematically review the literature with regard to the prevalence, incidence, risk factors and associations of primary Raynaud's phenomenon (PRP)...
  93. pmc Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan
    Chang Fu Kuo
    Department of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Ann Rheum Dis 74:369-74. 2015
    ..To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population...
  94. doi Optimizing current treatment of gout
    Frances Rees
    Division of Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital Nottingham, Hucknall Road, Nottingham NG5 1PB, UK
    Nat Rev Rheumatol 10:271-83. 2014
    ..Shared decision-making between a fully informed patient and practitioner greatly increases the likelihood of curing gout. ..
  95. doi Patient and provider barriers to effective management of gout in general practice: a qualitative study
    Karen Spencer
    University of Nottingham, Department of Academic Rheumatology, Academic Rheumatology Clinical Sciences Building City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 71:1490-5. 2012
    ..To explore patient and provider illness perceptions and barriers to effective management of gout in general practice...
  96. ncbi Lack of support for the presence of an osteoarthritis susceptibility locus on chromosome 6p
    Gary K Meenagh
    Department of Rheumatology, Musgrave Park Hospital, Belfast, UK
    Arthritis Rheum 52:2040-3. 2005
    ..To replicate, in a Northern Irish population, the previously reported association between a locus on chromosome 6 and hip osteoarthritis (OA)...
  97. pmc Development and validation of self-reported line drawings for assessment of knee malalignment and foot rotation: a cross-sectional comparative study
    Sarah L Ingham
    Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    BMC Med Res Methodol 10:57. 2010
    ..The study objectives were to develop and validate two novel instruments for self-reported knee malalignment and foot rotation suitable for use in questionnaire studies of knee pain and osteoarthritis...
  98. ncbi Age and sex differences in hip joint space among asymptomatic subjects without structural change: implications for epidemiologic studies
    Peter Lanyon
    Queen s Medical Centre, Nottingham, UK
    Arthritis Rheum 48:1041-6. 2003
    ..The aim of this study was to determine whether changes in joint space width occur with age, and whether there are sex differences, in asymptomatic subjects without hip OA...
  99. doi Does smoking protect against osteoarthritis? Meta-analysis of observational studies
    Michelle Hui
    Academic Rheumatology, University of Nottingham, UK
    Ann Rheum Dis 70:1231-7. 2011
    ..To determine whether smoking is protective against the development of osteoarthritis (OA)...
  100. doi Aspiration of normal or asymptomatic pathological joints for diagnosis and research: indications, technique and success rate
    E Pascual
    Professor M Doherty, Academic Rheumatology, Clinical Sciences Building, City Hospital, Nottingham, NG5 1PB, UK
    Ann Rheum Dis 68:3-7. 2009
    ..The justification for these indications, the success rate and the technical aspects related to this procedure are presented in this article...
  101. pmc Relationship between Heberden's nodes and underlying radiographic changes of osteoarthritis
    A Thaper
    Academic Rheumatology, University of Nottingham, Clinical Sciences Building, City Hospital, Nottingham NG5 1PB, UK
    Ann Rheum Dis 64:1214-6. 2005
    ..To determine whether clinically determined Heberden's nodes (HN) and Bouchard's nodes (BN) are associated with underlying individual radiographic changes of osteoarthritis (OA)...