Bill Deakin

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc A randomised double-blind placebo-controlled 12- week feasibility trial of methotrexate added to treatment as usual in early schizophrenia: study protocol for a randomised controlled trial
    Imran B Chaudhry
    University of Manchester and Lancashire Care Early Intervention Service, Manchester, UK
    Trials 16:9. 2015
  2. pmc Ondansetron and simvastatin added to treatment as usual in patients with schizophrenia: study protocol for a randomized controlled trial
    Imran B Chaudhry
    University of Manchester and Lancashire Care Early Intervention Service, The Mount Whalley Road, Accrington BB5 5DE, UK
    Trials 14:101. 2013
  3. pmc Assessment of the impact of the scanner-related factors on brain morphometry analysis with Brainvisa
    Mahsa Shokouhi
    Department of Clinical Physics and Psychological Medicine, College of Medicine, Veterinary and Life Sciences, University of Glasgow, UK
    BMC Med Imaging 11:23. 2011
  4. doi request reprint Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging study
    J F William Deakin
    Neuroscience and Psychiatry Unit, The University of Manchester, G 907 Stopford Building, Oxford Rd, Manchester M13 9PT, England
    Arch Gen Psychiatry 65:154-64. 2008
  5. doi request reprint State-dependent alteration in face emotion recognition in depression
    Ian M Anderson
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Br J Psychiatry 198:302-8. 2011
  6. doi request reprint Reduced medial prefrontal responses to social interaction images in remitted depression
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, England
    Arch Gen Psychiatry 69:37-45. 2012
  7. doi request reprint Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: a pharmacological-challenge fMRI (phMRI) study
    Shane McKie
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Neuroimage 58:497-507. 2011
  8. doi request reprint The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Biol Psychiatry 69:762-71. 2011
  9. doi request reprint The effect of acute citalopram on face emotion processing in remitted depression: a pharmacoMRI study
    Ian M Anderson
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, M13 9PT, UK
    Eur Neuropsychopharmacol 21:140-8. 2011
  10. pmc Affective cognition and its disruption in mood disorders
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, University of Manchester, Manchester, UK
    Neuropsychopharmacology 36:153-82. 2011

Collaborators

  • Ian M Anderson
  • Gabriella Juhasz
  • Shane McKie
  • Rebecca Elliott
  • Antony Payton
  • Paul Richardson
  • Birgit Völlm
  • Roland Zahn
  • Mairead Dolan
  • Judit Lazary
  • S M Dursun
  • Imran B Chaudhry
  • J F William Deakin
  • Steve R Williams
  • Nusrat Husain
  • Ajmal Kazmi
  • Raza Ur Rahman
  • Nasir Mehmood
  • Krisztina Mekli
  • Mahsa Shokouhi
  • Dan I Lubman
  • Cristina M Del-Ben
  • Shakeel Baig
  • Peter M Haddad
  • Inti Qureshi
  • Tayyeba Kiran
  • Mohammed Omair Husain
  • Bo Fu
  • Mohammed M Hamirani
  • Salahuddin Afsar
  • Maya H Buch
  • Richard Drake
  • Graham Dunn
  • Jamie Hallak
  • Mohammad M Hamirani
  • John Stirling
  • Mohammad O Husain
  • Tayyaba Kiran
  • David Brennan
  • Kathryn Lloyd-Williams
  • Emma Thomas
  • Barrie Condon
  • Diana Chase
  • John Suckling
  • Hazel Platt
  • Gyorgy Bagdy
  • Dominic Job
  • Zoltan G Toth
  • Katherine Lymer
  • Steven Cr Williams
  • Darragh Downey
  • Paola Dazzan
  • Stephen M Lawrie
  • Tiago Reis Marques
  • Fabio Miyajima
  • Anna Barnes
  • Clare Mackay
  • William E Ollier
  • Thomas Wj Moorhead
  • Jane Lees
  • Jaime E C Hallak
  • Lesley A Peters
  • Nicholas B Allen
  • Nicola A Delvai

Detail Information

Publications20

  1. pmc A randomised double-blind placebo-controlled 12- week feasibility trial of methotrexate added to treatment as usual in early schizophrenia: study protocol for a randomised controlled trial
    Imran B Chaudhry
    University of Manchester and Lancashire Care Early Intervention Service, Manchester, UK
    Trials 16:9. 2015
    ..Based on the evidence of the strong anti-inflammatory properties of methotrexate, we propose that low-dose methotrexate may be an effective therapy in early schizophrenia...
  2. pmc Ondansetron and simvastatin added to treatment as usual in patients with schizophrenia: study protocol for a randomized controlled trial
    Imran B Chaudhry
    University of Manchester and Lancashire Care Early Intervention Service, The Mount Whalley Road, Accrington BB5 5DE, UK
    Trials 14:101. 2013
    ..Small studies have suggested that ondansetron is effective as an adjunct drug in improving the symptoms of schizophrenia...
  3. pmc Assessment of the impact of the scanner-related factors on brain morphometry analysis with Brainvisa
    Mahsa Shokouhi
    Department of Clinical Physics and Psychological Medicine, College of Medicine, Veterinary and Life Sciences, University of Glasgow, UK
    BMC Med Imaging 11:23. 2011
    ..It is important therefore to investigate the variability and reliability of morphometric measurements between different scanners and different sessions of the same scanner...
  4. doi request reprint Glutamate and the neural basis of the subjective effects of ketamine: a pharmaco-magnetic resonance imaging study
    J F William Deakin
    Neuroscience and Psychiatry Unit, The University of Manchester, G 907 Stopford Building, Oxford Rd, Manchester M13 9PT, England
    Arch Gen Psychiatry 65:154-64. 2008
    ..Ketamine evokes psychosislike symptoms, and its primary action is to impair N-methyl-D-aspartate glutamate receptor neurotransmission, but it also induces secondary increases in glutamate release...
  5. doi request reprint State-dependent alteration in face emotion recognition in depression
    Ian M Anderson
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Br J Psychiatry 198:302-8. 2011
    ..Negative biases in emotional processing are well recognised in people who are currently depressed but are less well described in those with a history of depression, where such biases may contribute to vulnerability to relapse...
  6. doi request reprint Reduced medial prefrontal responses to social interaction images in remitted depression
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, England
    Arch Gen Psychiatry 69:37-45. 2012
    ..Stimuli with social context represent a distinct class of emotional stimuli, which in healthy volunteers are associated with specific neural substrates but have not previously been studied relative to vulnerability to depression...
  7. doi request reprint Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: a pharmacological-challenge fMRI (phMRI) study
    Shane McKie
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Neuroimage 58:497-507. 2011
    ..The results suggest that mCPP-challenge phMRI produces reliable patterns of response that are mediated by 5-HT(2C) receptors; these responses may therefore be useful in-vivo measures of 5-HT(2C) function in psychiatric disorders...
  8. doi request reprint The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, United Kingdom
    Biol Psychiatry 69:762-71. 2011
    ....
  9. doi request reprint The effect of acute citalopram on face emotion processing in remitted depression: a pharmacoMRI study
    Ian M Anderson
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, M13 9PT, UK
    Eur Neuropsychopharmacol 21:140-8. 2011
    ....
  10. pmc Affective cognition and its disruption in mood disorders
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, University of Manchester, Manchester, UK
    Neuropsychopharmacology 36:153-82. 2011
    ..The final section presents an overview of this literature and considers implications for understanding the pathophysiology of mood disorder as well as developing and evaluating new treatment strategies...
  11. pmc Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, The University of Manchester, Manchester, UK
    Neuropsychopharmacology 35:1109-19. 2010
    ..In conclusion, our study demonstrates the role of the TPH2 gene and the serotonin system in risk taking and suggests that TPH2 gene may contribute to the expression of psychiatric phenotypes through altered decision making...
  12. doi request reprint Variations in the cannabinoid receptor 1 gene predispose to migraine
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Neurosci Lett 461:116-20. 2009
    ..However, further studies are needed to elucidate the role of CNR1 and the cannabinoid system in migraine...
  13. doi request reprint CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms
    Gabriella Juhasz
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK
    Neuropsychopharmacology 34:2019-27. 2009
    ..This study also suggests that the CNR1 gene influences vulnerability to recent psychosocial adversity to produce current symptoms of depression...
  14. doi request reprint Co-operation with another player in a financially rewarded guessing game activates regions implicated in theory of mind
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester, UK
    Soc Neurosci 1:385-95. 2006
    ..Critically the response to reward in medial orbitofrontal cortex was significantly enhanced when subjects were co-operating. This suggests that rewards achieved through co-operation are more valuable than rewards achieved alone...
  15. ncbi request reprint Neuronal correlates of reward and loss in Cluster B personality disorders: a functional magnetic resonance imaging study
    Birgit Völlm
    Neuroscience and Psychiatry Unit, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK
    Psychiatry Res 156:151-67. 2007
    ..Our results suggest dysfunctional responses to rewarding and aversive stimuli in Cluster B personality disordered individuals but do not support the notion of hypersensitivity to reward and hyposensitivity to loss...
  16. ncbi request reprint Citalopram modulation of neuronal responses to aversive face emotions: a functional MRI study
    Ian M Anderson
    Neuroscience and Psychiatry Unit, The University of Manchester, Stopford Building, Oxford Road, Manchester, UK
    Neuroreport 18:1351-5. 2007
    ..No citalopram modulation of BOLD responses to angry faces were found. These results suggest that serotonin modulates low-level amygdala activation to aversive stimuli...
  17. doi request reprint The HTR1A and HTR1B receptor genes influence stress-related information processing
    Krisztina Mekli
    Neuroscience and Psychiatry Unit, School of Community Based Medicine, Faculty of Medical and Human Sciences, The University of Manchester, UK
    Eur Neuropsychopharmacol 21:129-39. 2011
    ....
  18. ncbi request reprint Differential response patterns in the striatum and orbitofrontal cortex to financial reward in humans: a parametric functional magnetic resonance imaging study
    Rebecca Elliott
    Neuroscience and Psychiatry Unit, University of Manchester, Manchester M13 9PT, United Kingdom
    J Neurosci 23:303-7. 2003
    ..These results suggest functional distinction in response patterns within a distributed reward system...
  19. ncbi request reprint The effect of citalopram pretreatment on neuronal responses to neuropsychological tasks in normal volunteers: an FMRI study
    Cristina M Del-Ben
    Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil
    Neuropsychopharmacology 30:1724-34. 2005
    ..The technique of combining drug challenge with fMRI (pharmacoMRI) has promise for investigating human psychiatric disorders...
  20. ncbi request reprint Electrophysiological evidence of the motivational salience of drug cues in opiate addiction
    Dan I Lubman
    ORYGEN Research Centre, Department of Psychiatry, University of Melbourne, Australia
    Psychol Med 37:1203-9. 2007
    ..We examined the motivational significance of drug cues in opiate dependence, by exploring their impact on central attentional processes...