Karen Davies

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. pmc Engaging the oldest old in research: lessons from the Newcastle 85+ study
    Karen Davies
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    BMC Geriatr 10:64. 2010
  2. pmc Improving retention of very old participants in longitudinal research: experiences from the Newcastle 85+ study
    Karen Davies
    Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e108370. 2014
  3. pmc Prevalence of left ventricular dysfunction in a UK community sample of very old people: the Newcastle 85+ study
    Fahad Yousaf
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Heart 98:1418-23. 2012
  4. pmc Losing the ability in activities of daily living in the oldest old: a hierarchic disability scale from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e31665. 2012
  5. pmc Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs
    Carol Jagger
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL UK
    BMC Geriatr 11:21. 2011
  6. doi request reprint Assessment of sleep and circadian rhythm disorders in the very old: the Newcastle 85+ Cohort Study
    Kirstie N Anderson
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 43:57-63. 2014
  7. pmc Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Neurobiol Aging 34:2889.e1-4. 2013
  8. pmc Utility of NT-proBNP as a rule-out test for left ventricular dysfunction in very old people with limiting dyspnoea: the Newcastle 85+ Study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK
    BMC Cardiovasc Disord 14:128. 2014
  9. pmc The association between diagnosed glaucoma and cataract and cognitive performance in very old people: cross-sectional findings from the newcastle 85+ study
    Joanna M Jefferis
    Institute for Ageing and Health, Newcastle University, UK
    Ophthalmic Epidemiol 20:82-8. 2013
  10. pmc The impact of visual impairment on Mini-Mental State Examination Scores in the Newcastle 85+ study
    Joanna Mary Jefferis
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 41:565-8. 2012

Collaborators

Detail Information

Publications25

  1. pmc Engaging the oldest old in research: lessons from the Newcastle 85+ study
    Karen Davies
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    BMC Geriatr 10:64. 2010
    ..This paper describes the methods employed for the successful recruitment, retention and evaluation of this cohort...
  2. pmc Improving retention of very old participants in longitudinal research: experiences from the Newcastle 85+ study
    Karen Davies
    Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e108370. 2014
    ..This paper describes the effectiveness of its retention strategies...
  3. pmc Prevalence of left ventricular dysfunction in a UK community sample of very old people: the Newcastle 85+ study
    Fahad Yousaf
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Heart 98:1418-23. 2012
    ..We used domiciliary echocardiography to estimate the prevalence of LV systolic and diastolic dysfunction in 87-89 year olds and the proportion remaining undiagnosed...
  4. pmc Losing the ability in activities of daily living in the oldest old: a hierarchic disability scale from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e31665. 2012
    ..To investigate the order in which 85 year olds develop difficulty in performing a wide range of daily activities covering basic personal care, household care and mobility...
  5. pmc Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs
    Carol Jagger
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL UK
    BMC Geriatr 11:21. 2011
    ..Little is known of the capabilities of the oldest old, the fastest growing age group in the population. We aimed to estimate capability and dependency in a cohort of 85 year olds and to project future demand for care...
  6. doi request reprint Assessment of sleep and circadian rhythm disorders in the very old: the Newcastle 85+ Cohort Study
    Kirstie N Anderson
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 43:57-63. 2014
    ..to examine the association between subjective and objective measures of sleep and wake and other health parameters in a cohort of the very old...
  7. pmc Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Neurobiol Aging 34:2889.e1-4. 2013
    ..Conflicting data from different populations underscore our conclusion that there is currently no compelling link between inherited mtDNA variants and aging. ..
  8. pmc Utility of NT-proBNP as a rule-out test for left ventricular dysfunction in very old people with limiting dyspnoea: the Newcastle 85+ Study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK
    BMC Cardiovasc Disord 14:128. 2014
    ..We examined NT-proBNP's utility, alone and in combination with history of myocardial infarction (MI), as a rule-out test for LV dysfunction in very old people with limiting dyspnoea...
  9. pmc The association between diagnosed glaucoma and cataract and cognitive performance in very old people: cross-sectional findings from the newcastle 85+ study
    Joanna M Jefferis
    Institute for Ageing and Health, Newcastle University, UK
    Ophthalmic Epidemiol 20:82-8. 2013
    ..Few studies have examined the relationship between cognition and cataract or glaucoma. We explored the association between cognition and cataract and glaucoma diagnoses in community-dwelling 85-year-olds...
  10. pmc The impact of visual impairment on Mini-Mental State Examination Scores in the Newcastle 85+ study
    Joanna Mary Jefferis
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Age Ageing 41:565-8. 2012
    ..This may be due to poor vision limiting performance on cognitive tasks specifically requiring vision, or an association between visual and neurodegenerative disorders...
  11. pmc The personal and health service impact of falls in 85 year olds: cross-sectional findings from the Newcastle 85+ cohort study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 7:e33078. 2012
    ..We investigated the prevalence and impact of falls, and the overlap between falls, dizziness and blackouts, in a population-based sample of 85 year olds...
  12. pmc Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old
    Laura Wiley
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e91005. 2014
    ..No associations were found between the measured parameters and age-related outcomes, including cognitive impairment, disability, co-morbidity and survival - questioning the validity of these parameters as candidate BoA in the very old. ..
  13. pmc The contribution of diseases to the male-female disability-survival paradox in the very old: results from the Newcastle 85+ study
    Andrew Kingston
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 9:e88016. 2014
    ..Less is known about the paradox in the very old. We examine sex differences in the presence and impact of disabling and fatal diseases accounting for the male-female disability-survival paradox in very late life...
  14. doi request reprint Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, United Kingdom
    Mech Ageing Dev 133:456-66. 2012
    ..Difficulties in operationalizing the Fried model, due to high levels of co-morbidity, limit its utility in the very old...
  15. pmc Dietary Patterns and Socioeconomic Status in the Very Old: The Newcastle 85+ Study
    Antoneta Granic
    Newcastle University Institute for Ageing, Newcastle upon Tyne, United Kingdom Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 10:e0139713. 2015
    ..Higher socioeconomic status (SES) has been linked with healthier DP but it is not known whether these associations are sustained in the very old...
  16. pmc Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study
    Joanna Collerton
    Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK Institute of Health and Society, Newcastle University, Baddiley Clark building, Richardson Road, Newcastle upon Tyne NE2 4AX, UK
    Biomed Res Int 2016:8745670. 2016
    ..Elaborating participant clusters sharing similar morbidity profiles will help inform future healthcare provision and the identification of common underlying biological mechanisms. ..
  17. doi request reprint Serum osmolarity and haematocrit do not modify the association between the impedance index (Ht(2)/Z) and total body water in the very old: the Newcastle 85+ study
    Mario Siervo
    Institute of Cellular Medicine, Newcastle University, Campus for Ageing and Vitality, Newcastle on Tyne NE4 5PL, UK Electronic address
    Arch Gerontol Geriatr 60:227-32. 2015
    ..We investigated whether the association between the impedance index and total body water (TBW) was modified by hydration status as assessed by haematocrit and serum osmolarity...
  18. doi request reprint Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    Biogerontology 15:317-28. 2014
    ..47 (95 % CI 0.26-0.85); n = 321, p = 0.013]. Overall this study suggests a potential role for age-related changes in CpG island methylation in the development of frailty. ..
  19. doi request reprint Assessment of a large panel of candidate biomarkers of ageing in the Newcastle 85+ study
    Carmen Martin-Ruiz
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Mech Ageing Dev 132:496-502. 2011
    ..As future data accrues on health outcomes within the cohort, it will become possible also to evaluate the predictive value of these and others of the candidate biomarkers...
  20. pmc A comparison of subjective and objective measures of physical activity from the Newcastle 85+ study
    Paul Innerd
    Newcastle Institute for Ageing, Newcastle University, The Medical School, 4th Floor William Leech Building, Newcastle upon Tyne NE2 4HH, UK
    Age Ageing 44:691-4. 2015
    ..Little is known about physical activity (PA) in the very old, the fastest growing age group in the population. We aimed to examine the convergent validity of subjective and objective measures of PA in adults aged over 85 years...
  21. doi request reprint Is there an association between metabolic syndrome and cognitive function in very old adults? The Newcastle 85+ Study
    Stephanie L Harrison
    Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
    J Am Geriatr Soc 63:667-75. 2015
    ....
  22. doi request reprint Antihypertensive drug use and risk of cognitive decline in the very old: an observational study - the Newcastle 85+ Study
    Ruth Peters
    aImperial Clinical Trials Unit, School of Public Health, St Mary s Campus, Imperial College London bInstitute of Health and Society cInstitute for Cell and Molecular Biosciences, Newcastle University dNewcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    J Hypertens 33:2156-64. 2015
    ..We used observational data to examine the association between antihypertensive drug class and change in cognitive function...
  23. pmc Respiratory health and disease in a UK population-based cohort of 85 year olds: The Newcastle 85+ Study
    Andrew J Fisher
    Department of Respiratory Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK
    Thorax 71:255-66. 2016
    ....
  24. pmc Health and disease in 85 year olds: baseline findings from the Newcastle 85+ cohort study
    Joanna Collerton
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL
    BMJ 339:b4904. 2009
    ....
  25. doi request reprint Nutrition in advanced age: dietary assessment in the Newcastle 85+ study
    A J Adamson
    Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK
    Eur J Clin Nutr 63:S6-18. 2009
    ..This paper describes a comparison of two different methods of dietary assessment within the Newcastle 85+ Study; a UK cohort study of health and ageing in the oldest old...