Colin M Crump

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Alphaherpesvirus glycoprotein M causes the relocalization of plasma membrane proteins
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Gen Virol 85:3517-27. 2004
  2. pmc Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 81:7380-7. 2007
  3. pmc HSV-1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin-Dependent Endocytosis
    Anna Albecka
    Division of Virology, Department of Pathology, Cambridge University, Cambridge, CB2 1QP, UK
    Traffic 17:21-39. 2016
  4. doi request reprint Glycoprotein M is important for the efficient incorporation of glycoprotein H-L into herpes simplex virus type 1 particles
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Gen Virol 93:319-29. 2012
  5. pmc Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment
    Helen L Zenner
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Virol 85:8012-21. 2011
  6. pmc Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity
    Helen L Zenner
    Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 87:13115-23. 2013
  7. doi request reprint Photo inactivation of virus particles in microfluidic capillary systems
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Biotechnol Bioeng 113:1481-92. 2016
  8. pmc Herpes simplex virus type 1 production requires a functional ESCRT-III complex but is independent of TSG101 and ALIX expression
    Tobias Pawliczek
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 83:11254-64. 2009
  9. pmc Analysis of the interaction between the essential herpes simplex virus 1 tegument proteins VP16 and VP1/2
    Stanislava Svobodova
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 86:473-83. 2012
  10. doi request reprint Cover Image, Volume 113, Number 7, July 2016
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Biotechnol Bioeng 113:i. 2016

Collaborators

  • Francis A Barr
  • Emily A Bruce
  • Lisa E Pomeranz
  • Katherine Bowers
  • Amanda D Stuart
  • Yudan Ren
  • Helen L Zenner
  • Nuno M Reis
  • Malcolm M Mackley
  • Anna Albecka
  • Gianluca Li Puma
  • Susanne Bell
  • Stanislava Svobodova
  • Tobias Pawliczek
  • Thomas Simmen
  • Laurel Thomas
  • Gary Thomas
  • Yang Xiang
  • Lei Wan
  • Romain F Laine
  • Gregory K Scott
  • Clemens F Kaminski
  • Anne F J Janssen
  • George Banting
  • Rui Mauricio
  • S Y Kathy Lau
  • Shin ichiro Yoshimura
  • Sylvain F Feliciangeli
  • Joseph E Aslan
  • Chien Hui Hung
  • Anastassia D Blagoveshchenskaya
  • Feng Gu

Detail Information

Publications14

  1. ncbi request reprint Alphaherpesvirus glycoprotein M causes the relocalization of plasma membrane proteins
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Gen Virol 85:3517-27. 2004
    ..These data suggest that herpesvirus gM (gM/N) can alter the membrane trafficking itineraries of a broad range of proteins and this may have multiple functions...
  2. pmc Herpes simplex virus type 1 cytoplasmic envelopment requires functional Vps4
    Colin M Crump
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 81:7380-7. 2007
    ..This is the first example of a large enveloped DNA virus engaging the multivesicular endosome sorting machinery to enable infectious virus production...
  3. pmc HSV-1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin-Dependent Endocytosis
    Anna Albecka
    Division of Virology, Department of Pathology, Cambridge University, Cambridge, CB2 1QP, UK
    Traffic 17:21-39. 2016
    ..This highlights the importance of endocytosis as a major protein-sorting event during HSV-1 envelopment. ..
  4. doi request reprint Glycoprotein M is important for the efficient incorporation of glycoprotein H-L into herpes simplex virus type 1 particles
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Gen Virol 93:319-29. 2012
    ..These data suggest an important role of gM in mediating the specific internalization and efficient targeting of gH-L to sites of secondary envelopment in infected cells...
  5. pmc Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment
    Helen L Zenner
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK
    J Virol 85:8012-21. 2011
    ....
  6. pmc Herpes simplex virus 1 counteracts tetherin restriction via its virion host shutoff activity
    Helen L Zenner
    Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 87:13115-23. 2013
    ..Taken together, our data suggest that tetherin has antiviral activity toward HSV-1 and that the removal of tetherin by Vhs is important for the efficient replication and dissemination of HSV-1. ..
  7. doi request reprint Photo inactivation of virus particles in microfluidic capillary systems
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Biotechnol Bioeng 113:1481-92. 2016
    ..Biotechnol. Bioeng. 2016;113: 1481-1492. © 2015 Wiley Periodicals, Inc. ..
  8. pmc Herpes simplex virus type 1 production requires a functional ESCRT-III complex but is independent of TSG101 and ALIX expression
    Tobias Pawliczek
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Virol 83:11254-64. 2009
    ..In line with these data, we also find that ESCRT-III proteins and VPS4A/B are specifically incorporated into mature HSV-1 virions...
  9. pmc Analysis of the interaction between the essential herpes simplex virus 1 tegument proteins VP16 and VP1/2
    Stanislava Svobodova
    Division of Virology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom
    J Virol 86:473-83. 2012
    ..These data also support the notion that the incorporation of tegument proteins into the herpesviruses is a very complex process with significant redundancy...
  10. doi request reprint Cover Image, Volume 113, Number 7, July 2016
    Yudan Ren
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Biotechnol Bioeng 113:i. 2016
    ..The cover image, by Nuno Miguel Reis et al., is based on the Article Photo inactivation of virus particles in microfluidic capillary systems, DOI: 10.1002/bit.25912. ..
  11. doi request reprint Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway
    Emily A Bruce
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Virology 390:268-78. 2009
    ..Overall, we see no role for the ESCRT pathway in influenza virus budding and the significance of the M1-VPS28 interaction remains to be determined...
  12. pmc Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production
    Colin M Crump
    Vollum Institute, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Virol 77:11105-13. 2003
    ....
  13. pmc The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic
    Gregory K Scott
    Vollum Institute, L 474, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA
    EMBO J 22:6234-44. 2003
    ..These results suggest that coordinated signaling events regulate transport within the TGN/endosomal system through the phosphorylation state of both cargo and the sorting machinery...
  14. pmc PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
    Thomas Simmen
    Vollum Institute, Portland, OR 97239 3098, USA
    EMBO J 24:717-29. 2005
    ..Together, our results identify PACS-2 as a novel sorting protein that links the ER-mitochondria axis to ER homeostasis and the control of cell fate, and provide new insights into Bid action...