Matthew J Brookes

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc A multi-layer network approach to MEG connectivity analysis
    Matthew J Brookes
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom Electronic address
    Neuroimage 132:425-38. 2016
  2. doi request reprint Measuring temporal, spectral and spatial changes in electrophysiological brain network connectivity
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK Electronic address
    Neuroimage 91:282-99. 2014
  3. doi request reprint Task induced modulation of neural oscillations in electrophysiological brain networks
    M J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, UK
    Neuroimage 63:1918-30. 2012
  4. pmc Measuring functional connectivity in MEG: a multivariate approach insensitive to linear source leakage
    M J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 63:910-20. 2012
  5. pmc Investigating the electrophysiological basis of resting state networks using magnetoencephalography
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG72RD, United Kingdom
    Proc Natl Acad Sci U S A 108:16783-8. 2011
  6. doi request reprint Source localisation in concurrent EEG/fMRI: applications at 7T
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Neuroimage 45:440-52. 2009
  7. pmc Measuring functional connectivity using MEG: methodology and comparison with fcMRI
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 56:1082-104. 2011
  8. doi request reprint Changes in brain network activity during working memory tasks: a magnetoencephalography study
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 55:1804-15. 2011
  9. ncbi request reprint GLM-beamformer method demonstrates stationary field, alpha ERD and gamma ERS co-localisation with fMRI BOLD response in visual cortex
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, UK
    Neuroimage 26:302-8. 2005
  10. pmc Investigating spatial specificity and data averaging in MEG
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 49:525-38. 2010

Collaborators

Detail Information

Publications37

  1. pmc A multi-layer network approach to MEG connectivity analysis
    Matthew J Brookes
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom Electronic address
    Neuroimage 132:425-38. 2016
    ..Our findings demonstrate the unique potential of MEG to characterise neural network formation and dissolution. Further, we add weight to the argument that dysconnectivity is a core feature of the neuropathology underlying schizophrenia. ..
  2. doi request reprint Measuring temporal, spectral and spatial changes in electrophysiological brain network connectivity
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK Electronic address
    Neuroimage 91:282-99. 2014
    ..The feasibility of this technique is demonstrated in simulation and in a resting state MEG experiment where we elucidate multiple distinct spatio-temporal-spectral modes of covariation between the left and right sensorimotor areas. ..
  3. doi request reprint Task induced modulation of neural oscillations in electrophysiological brain networks
    M J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, UK
    Neuroimage 63:1918-30. 2012
    ..This study furthers recent findings on electrodynamic brain networks and paves the way for future clinical studies in patients in which abnormal connectivity is thought to underlie core symptoms...
  4. pmc Measuring functional connectivity in MEG: a multivariate approach insensitive to linear source leakage
    M J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 63:910-20. 2012
    ..Given a significant interaction between two areas, we go on to show how classical statistical tests can be used to quantify the importance of the data features driving the interaction...
  5. pmc Investigating the electrophysiological basis of resting state networks using magnetoencephalography
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG72RD, United Kingdom
    Proc Natl Acad Sci U S A 108:16783-8. 2011
    ..This outcome confirms the neural basis of hemodynamic networks and demonstrates the potential of MEG as a tool for understanding the mechanisms that underlie RSNs and the nature of connectivity that binds network nodes...
  6. doi request reprint Source localisation in concurrent EEG/fMRI: applications at 7T
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Neuroimage 45:440-52. 2009
    ..Finally, in-vivo experiments conducted at 7T show that effects in the gamma band can be recorded using simultaneous EEG/fMRI. These results are achieved by application of beamformer methodology to 64 channel EEG data...
  7. pmc Measuring functional connectivity using MEG: methodology and comparison with fcMRI
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 56:1082-104. 2011
    ..Our results extend those from previous studies and add weight to the argument that neural oscillations are intimately related to functional connectivity and the BOLD response...
  8. doi request reprint Changes in brain network activity during working memory tasks: a magnetoencephalography study
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 55:1804-15. 2011
    ....
  9. ncbi request reprint GLM-beamformer method demonstrates stationary field, alpha ERD and gamma ERS co-localisation with fMRI BOLD response in visual cortex
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, UK
    Neuroimage 26:302-8. 2005
    ....
  10. pmc Investigating spatial specificity and data averaging in MEG
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 49:525-38. 2010
    ..We suggest that future comparisons of MEG source localisation techniques (e.g. beamformer, minimum norm, Bayesian) could be made using this retinotopic mapping paradigm...
  11. pmc Abnormal salience signaling in schizophrenia: The role of integrative beta oscillations
    Elizabeth B Liddle
    Institute of Mental Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom
    Hum Brain Mapp 37:1361-74. 2016
    ....
  12. ncbi request reprint Optimising experimental design for MEG beamformer imaging
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage 39:1788-802. 2008
    ..However, large amounts of regularisation cause a loss in the spatial resolution of the MEG beamformer, hence regularisation should be used carefully, particularly if multiple sources in close proximity are expected...
  13. doi request reprint The effect of hypercapnia on resting and stimulus induced MEG signals
    Emma L Hall
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, UK
    Neuroimage 58:1034-43. 2011
    ..This work supports invasive recordings made in animals, and the results have potential implications for calibrated BOLD studies...
  14. doi request reprint Relating BOLD fMRI and neural oscillations through convolution and optimal linear weighting
    Johanna M Zumer
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Neuroimage 49:1479-89. 2010
    ..Conversely, deconvolution of BOLD data provides a neural estimate which correlates well with measured neural effects as a function of neural oscillation frequency...
  15. doi request reprint Simultaneous EEG source localisation and artifact rejection during concurrent fMRI by means of spatial filtering
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Neuroimage 40:1090-104. 2008
    ..We show that the EEG-beamformer can eliminate effectively the ballistocardiogram artifact as well as residual gradient artifacts that remain in EEG data following correction using averaged artifact subtraction techniques...
  16. ncbi request reprint Beamformer reconstruction of correlated sources using a modified source model
    Matthew J Brookes
    The Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Neuroimage 34:1454-65. 2007
    ..Such a priori information could be based on previous studies using similar paradigms, or from other functional neuroimaging techniques...
  17. doi request reprint Using variance information in magnetoencephalography measures of functional connectivity
    Emma L Hall
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
    Neuroimage 67:203-12. 2013
    ..We therefore suggest that this approach be incorporated into future studies...
  18. doi request reprint Comparison of functional connectivity in default mode and sensorimotor networks at 3 and 7T
    Joanne R Hale
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    MAGMA 23:339-49. 2010
    ..The objective of this work was to assess functional connectivity measurements at ultra-high field (7T), given BOLD contrast to noise ratio increases with magnetic field strength but physiological noise also increases...
  19. doi request reprint Broadband cortical desynchronization underlies the human psychedelic state
    Suresh D Muthukumaraswamy
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff CF119BJ, United Kingdom, Imperial College London, Centre for Neuropsychopharmacology, Division of Brain Sciences, Faculty of Medicine, London W12 ONN, United Kingdom, Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, United Kingdom, Sir Peter Mansfield Magnetic Resonance Centre, Nottingham University, Nottingham NG7 2RD, United Kingdom, Academic Unit of Psychiatry, University of Bristol, Bristol BS8 2BN, United Kingdom, The Beckley Foundation, Beckley Park, Oxford OX3 9SY, United Kingdom, and Virginia Tech Carilion Research Institute, and Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Roanoke, Virginia 24016
    J Neurosci 33:15171-83. 2013
    ..These findings suggest that the subjective effects of psychedelics result from a desynchronization of ongoing oscillatory rhythms in the cortex, likely triggered by 5-HT2A receptor-mediated excitation of deep pyramidal cells...
  20. doi request reprint 3 Tesla and 7 Tesla MRI of multiple sclerosis cortical lesions
    Emma C Tallantyre
    Department of Clinical Neurology, University of Nottingham, Nottingham, United Kingdom
    J Magn Reson Imaging 32:971-7. 2010
    ..High resolution 7T imaging may facilitate anatomical localization of lesions in relation to the cortical boundary...
  21. pmc Complexity measures in magnetoencephalography: measuring "disorder" in schizophrenia
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, United Kingdom
    PLoS ONE 10:e0120991. 2015
    ....
  22. doi request reprint β-Band correlates of the fMRI BOLD response
    Claire M Stevenson
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, United Kingdom
    Hum Brain Mapp 32:182-97. 2011
    ..The amplitude of β-desynchronization in the central visual area is however modulated by drift frequency, and this seems to parallel the modulation in BOLD amplitude at the same location...
  23. ncbi request reprint T2* measurements in human brain at 1.5, 3 and 7 T
    Andrew M Peters
    Sir Peter Mansfield Magnetic Resonance Center, School of Physics and Astronomy, University of Nottingham, NG7 2RD Nottingham, UK
    Magn Reson Imaging 25:748-53. 2007
    ....
  24. pmc Measurement of dynamic task related functional networks using MEG
    George C O'Neill
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage . 2016
    ..Our method tracks the dynamics of functional connectivity in the brain on a timescale commensurate to the task they are undertaking...
  25. pmc Relationships between cortical myeloarchitecture and electrophysiological networks
    Benjamin A E Hunt
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD, United Kingdom
    Proc Natl Acad Sci U S A 113:13510-13515. 2016
    ..Our study sheds light on the way in which cortical microstructure supports functional networks. Further, it paves the way for future investigations of the gray-matter structure/function relationship and its breakdown in pathology...
  26. doi request reprint The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG
    Paula L Croal
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
    Neuroimage 105:323-31. 2015
    ..The effect of this change in neural activity on calibrated BOLD using hyperoxia or combined hyperoxia and hypercapnia needs further investigation...
  27. pmc Functional Connectivity in MRI Is Driven by Spontaneous BOLD Events
    Thomas W Allan
    Sir Peter Mansfield Imagaing Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, United Kingdom
    PLoS ONE 10:e0124577. 2015
    ....
  28. ncbi request reprint A general linear model for MEG beamformer imaging
    Matthew J Brookes
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Neuroimage 23:936-46. 2004
    ..The new method brings the advantages of the general linear model to the analysis of MEG data and should prove useful for the localization of changing patterns of activity across all frequency ranges including DC (sustained fields)...
  29. doi request reprint A New Generation of Magnetoencephalography: Room Temperature Measurements using Optically-Pumped Magnetometers
    Elena Boto
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom
    Neuroimage . 2017
    ..Our results highlight the opportunity presented by OPMs to generate uncooled, potentially low-cost, high SNR MEG systems...
  30. doi request reprint Integrating cross-frequency and within band functional networks in resting-state MEG: A multi-layer network approach
    Prejaas Tewarie
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom Electronic address
    Neuroimage 142:324-336. 2016
    ..Overall, our observations show that a complete picture of global brain network connectivity requires integration of connectivity patterns across the full frequency spectrum...
  31. doi request reprint Optimising experimental design for MEG resting state functional connectivity measurement
    Lucrezia Liuzzi
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK
    Neuroimage . 2016
    ..Our results provide important insights on experimental design and will prove valuable for future MEG connectivity studies...
  32. pmc Dynamic recruitment of resting state sub-networks
    George C O'Neill
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom
    Neuroimage 115:85-95. 2015
    ..Our approach opens new frontiers to study RSN dynamics, showing that MEG is capable of revealing the spatial, temporal and spectral signature of the human connectome in health and disease. ..
  33. doi request reprint Measuring electrophysiological connectivity by power envelope correlation: a technical review on MEG methods
    George C O'Neill
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
    Phys Med Biol 60:R271-95. 2015
    ....
  34. pmc On the Potential of a New Generation of Magnetometers for MEG: A Beamformer Simulation Study
    Elena Boto
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, NG7 2RD, Nottingham, United Kingdom
    PLoS ONE 11:e0157655. 2016
    ..However in practice, this will require both improved hardware and modelling algorithms. ..
  35. pmc Abnormal visuomotor processing in schizophrenia
    Siân E Robson
    Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Neuroimage Clin 12:869-878. 2016
    ..These data demonstrate that clear abnormalities in basic sensorimotor processing in schizophrenia can be observed using a very simple MEG paradigm...
  36. doi request reprint The relationship between MEG and fMRI
    Emma L Hall
    Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, UK
    Neuroimage 102:80-91. 2014
    ..Finally, we highlight future areas of interest and offer some recommendations for the parallel use of fMRI and MEG. ..
  37. doi request reprint A comparison of 3T and 7T in the detection of small parenchymal veins within MS lesions
    Emma C Tallantyre
    Department of Clinical Neurology, Medical School, University of Nottingham, Nottingham, United Kingdom
    Invest Radiol 44:491-4. 2009
    ....