Peter Brocklehurst

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Repeat prenatal corticosteroid prior to preterm birth: a systematic review and individual participant data meta-analysis for the PRECISE study group (prenatal repeat corticosteroid international IPD study group: assessing the effects using the best level
    Caroline A Crowther
    Australian Research Centre for Health of Women and Babies ARCH, Discipline of Obstetrics and Gynaecology, The University of Adelaide, Women s and Children s Hospital, Adelaide, Australia
    Syst Rev 1:12. 2012
  2. pmc The BRACELET Study: surveys of mortality in UK neonatal and paediatric intensive care trials
    Claire Snowdon
    Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, UK
    Trials 11:65. 2010
  3. pmc MRC ORACLE Children Study. Long term outcomes following prescription of antibiotics to pregnant women with either spontaneous preterm labour or preterm rupture of the membranes
    Sara Kenyon
    Reproductive Sciences Section, University of Leicester, Leicester, LE2 7LX, UK
    BMC Pregnancy Childbirth 8:14. 2008
  4. pmc Evidence into practice: evaluating a child-centred intervention for diabetes medicine management. The EPIC Project
    Jane P Noyes
    Centre for Health Related Research, Bangor University, Bangor, UK
    BMC Pediatr 10:70. 2010
  5. pmc Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trial
    David J Field
    Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    BMC Pediatr 10:24. 2010
  6. pmc ADEPT - Abnormal Doppler Enteral Prescription Trial
    Alison Leaf
    Neonatal Unit, Southmead Hospital, Bristol, UK
    BMC Pediatr 9:63. 2009
  7. pmc The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial
    Dennis Azzopardi
    Division of Clinical Sciences, Faculty of Medicine, Imperial College London, UK
    BMC Pediatr 8:17. 2008
  8. pmc NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol
    Lisa M Askie
    NHMRC Clinical Trials Centre, University of Sydney, Parramatta Road, Camperdown, 2050, Australia
    BMC Pediatr 11:6. 2011
  9. pmc The effect of a monetary incentive on return of a postal health and development questionnaire: a randomised trial [ISRCTN53994660]
    Sara Kenyon
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK
    BMC Health Serv Res 5:55. 2005
  10. pmc Effect on survey response rate of hand written versus printed signature on a covering letter: randomised controlled trial [ISRCTN67566265]
    Kirstie McKenzie-McHarg
    National Perinatal Epidemiology Unit University of Oxford Old Road Campus Oxford OX3 LF UK
    BMC Health Serv Res 5:52. 2005

Collaborators

Detail Information

Publications47

  1. pmc Repeat prenatal corticosteroid prior to preterm birth: a systematic review and individual participant data meta-analysis for the PRECISE study group (prenatal repeat corticosteroid international IPD study group: assessing the effects using the best level
    Caroline A Crowther
    Australian Research Centre for Health of Women and Babies ARCH, Discipline of Obstetrics and Gynaecology, The University of Adelaide, Women s and Children s Hospital, Adelaide, Australia
    Syst Rev 1:12. 2012
    ....
  2. pmc The BRACELET Study: surveys of mortality in UK neonatal and paediatric intensive care trials
    Claire Snowdon
    Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, UK
    Trials 11:65. 2010
    ..These are essential prerequisites to considering the implications of future policies and practice subsequent to bereavement following a child's enrollment in a trial...
  3. pmc MRC ORACLE Children Study. Long term outcomes following prescription of antibiotics to pregnant women with either spontaneous preterm labour or preterm rupture of the membranes
    Sara Kenyon
    Reproductive Sciences Section, University of Leicester, Leicester, LE2 7LX, UK
    BMC Pregnancy Childbirth 8:14. 2008
    ....
  4. pmc Evidence into practice: evaluating a child-centred intervention for diabetes medicine management. The EPIC Project
    Jane P Noyes
    Centre for Health Related Research, Bangor University, Bangor, UK
    BMC Pediatr 10:70. 2010
    ..The aim of the diabetes information intervention is to improve children and young people's quality of life by increasing self-efficacy in managing their type 1 diabetes...
  5. pmc Neonatal ECMO Study of Temperature (NEST)--a randomised controlled trial
    David J Field
    Department of Heath Science, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    BMC Pediatr 10:24. 2010
    ..Infants allocated to the control group will receive ECMO at 37 degrees C throughout their course, which is currently standard practice around the world. Health status of both groups will be assessed formally at 2 years corrected age...
  6. pmc ADEPT - Abnormal Doppler Enteral Prescription Trial
    Alison Leaf
    Neonatal Unit, Southmead Hospital, Bristol, UK
    BMC Pediatr 9:63. 2009
    ..Optimising neonatal feeding for this group of babies may have long-term health implications and if either of these policies is shown to be beneficial it can be immediately adopted into clinical practice...
  7. pmc The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial
    Dennis Azzopardi
    Division of Clinical Sciences, Faculty of Medicine, Imperial College London, UK
    BMC Pediatr 8:17. 2008
    ..5 degrees C have been reported. No complications were noted but the group sizes were too small to evaluate benefit...
  8. pmc NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol
    Lisa M Askie
    NHMRC Clinical Trials Centre, University of Sydney, Parramatta Road, Camperdown, 2050, Australia
    BMC Pediatr 11:6. 2011
    ..In order to answer this clinical dilemma reliably, large scale trial evidence is needed...
  9. pmc The effect of a monetary incentive on return of a postal health and development questionnaire: a randomised trial [ISRCTN53994660]
    Sara Kenyon
    Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK
    BMC Health Serv Res 5:55. 2005
    ..There was a lack of evidence available relating to use of a monetary incentive to improve the response rate in the healthcare setting...
  10. pmc Effect on survey response rate of hand written versus printed signature on a covering letter: randomised controlled trial [ISRCTN67566265]
    Kirstie McKenzie-McHarg
    National Perinatal Epidemiology Unit University of Oxford Old Road Campus Oxford OX3 LF UK
    BMC Health Serv Res 5:52. 2005
    ....
  11. pmc Inequalities in maternal health: national cohort study of ethnic variation in severe maternal morbidities
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Oxford
    BMJ 338:b542. 2009
    ..To describe on a national basis ethnic differences in severe maternal morbidity in the United Kingdom...
  12. pmc Service configuration, unit characteristics and variation in intervention rates in a national sample of obstetric units in England: an exploratory analysis
    Rachel E Rowe
    National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK
    BMJ Open 4:e005551. 2014
    ..To explore whether service configuration and obstetric unit (OU) characteristics explain variation in OU intervention rates in 'low-risk' women...
  13. doi request reprint Incidence and risk factors for amniotic-fluid embolism
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Obstet Gynecol 115:910-7. 2010
    ..To estimate the incidence of amniotic-fluid embolism and to describe risk factors, management, and outcomes...
  14. pmc Incidence and risk factors for placenta accreta/increta/percreta in the UK: a national case-control study
    Kathryn E Fitzpatrick
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    PLoS ONE 7:e52893. 2012
    ..The aims of this study were to estimate the incidence of placenta accreta/increta/percreta in the UK and to investigate and quantify the associated risk factors...
  15. doi request reprint Maternal and obstetric factors associated with delayed postpartum eclampsia: a national study population
    Gilles Kayem
    National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Oxford, UK
    Acta Obstet Gynecol Scand 90:1017-23. 2011
    ..To estimate the incidence of delayed postpartum eclampsia and to investigate whether maternal characteristics and outcomes were different between women with delayed or early postpartum eclampsia...
  16. doi request reprint Extreme obesity in pregnancy in the United Kingdom
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Obstet Gynecol 115:989-97. 2010
    ..To estimate the prevalence and describe on a national basis the management and outcomes of extreme obesity (body mass index [BMI] 50 kg/m or higher) in pregnancy in the United Kingdom...
  17. pmc Amniotic fluid embolism incidence, risk factors and outcomes: a review and recommendations
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK
    BMC Pregnancy Childbirth 12:7. 2012
    ....
  18. pmc Uterine rupture by intended mode of delivery in the UK: a national case-control study
    Kathryn E Fitzpatrick
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK
    PLoS Med 9:e1001184. 2012
    ..The aims of this study were to estimate the incidence of true uterine rupture in the UK and to investigate and quantify the associated risk factors and outcomes, on the basis of intended mode of delivery...
  19. pmc Perinatal outcomes after maternal 2009/H1N1 infection: national cohort study
    Matthias Pierce
    National Perinatal Epidemiology Unit, University of Oxford, Oxford OX3 7LF, UK
    BMJ 342:d3214. 2011
    ..To follow up a UK national cohort of women admitted to hospital with confirmed 2009/H1N1 influenza in pregnancy in order to obtain a complete picture of pregnancy outcomes and estimate the risks of adverse fetal and infant outcomes...
  20. pmc Duration and urgency of transfer in births planned at home and in freestanding midwifery units in England: secondary analysis of the birthplace national prospective cohort study
    Rachel E Rowe
    National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Oxford OX3 7LF, UK
    BMC Pregnancy Childbirth 13:224. 2013
    ..We aimed to estimate the duration of transfer in births planned at home and in FMUs and explore the effects of distance and urgency on duration...
  21. ncbi request reprint Uterine compression sutures for the management of severe postpartum hemorrhage
    Gilles Kayem
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Obstet Gynecol 117:14-20. 2011
    ..To assess maternal outcomes after uterine compression suture use and to characterize the risk factors for failure, defined as cases that proceeded to hysterectomy...
  22. doi request reprint Incidence, risk factors, management, and outcomes of stroke in pregnancy
    Catherine A Scott
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    Obstet Gynecol 120:318-24. 2012
    ..To estimate the incidence of antenatal stroke in the United Kingdom and to describe risk factors associated with stroke during pregnancy, management, and outcomes...
  23. pmc Risk factors for progression from severe maternal morbidity to death: a national cohort study
    Gilles Kayem
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, United Kingdom
    PLoS ONE 6:e29077. 2011
    ..The aim of this analysis was to compare women with severe maternal morbidities who survived with those who died, to quantify the risk associated with identified factors to inform policy and practice to improve survival...
  24. pmc The effectiveness of antenatal care programmes to reduce infant mortality and preterm birth in socially disadvantaged and vulnerable women in high-income countries: a systematic review
    Jennifer Hollowell
    National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK
    BMC Pregnancy Childbirth 11:13. 2011
    ....
  25. doi request reprint Cesarean delivery and peripartum hysterectomy
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, United Kingdom
    Obstet Gynecol 111:97-105. 2008
    ..To estimate the national incidence of peripartum hysterectomy and quantify the risk associated with cesarean deliveries and other factors...
  26. doi request reprint Social and ethnic inequalities in infant mortality: a perspective from the United kingdom
    Jennifer Hollowell
    National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK
    Semin Perinatol 35:240-4. 2011
    ..Policies and interventions to tackle these inequalities are likely to be most effective if they have both universal and targeted components to "level-up" rates to the rate of the most advantaged in society...
  27. pmc Pregnancy in renal transplant recipients: a UK national cohort study
    Kate Bramham
    Division of Women s Health, Women s Health Academic Centre, King s Health Partners, King s College London, London, UK
    Clin J Am Soc Nephrol 8:290-8. 2013
    ....
  28. ncbi request reprint The UK Obstetric Surveillance System for rare disorders of pregnancy
    Marian Knight
    National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Oxford, UK
    BJOG 112:263-5. 2005
  29. ncbi request reprint Thromboprophylaxis and pregnancy: two randomized controlled pilot trials that used low-molecular-weight heparin
    Simon Gates
    National Perinatal Epidemiology Unit, University of Oxford, Old Campus Road, Oxford OX 3 7LF, United Kingdom
    Am J Obstet Gynecol 191:1296-303. 2004
    ....
  30. doi request reprint A prospective national study of acute fatty liver of pregnancy in the UK
    M Knight
    National Perinatal Epidemiology Unit, University of Oxford, UK
    Gut 57:951-6. 2008
    ..To identify a national, population-based cohort of women with acute fatty liver of pregnancy (AFLP), to evaluate proposed diagnostic criteria and to document accurately the incidence, management and outcomes of the condition...
  31. pmc Examining the impact of introducing ICD-MM on observed trends in maternal mortality rates in the UK 2003-13
    Marian Knight
    National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Old Road Campus, Headington, Oxford, OX3 7LF, UK
    BMC Pregnancy Childbirth 16:178. 2016
    ..The aim of this analysis was to examine the trends in maternal deaths in the UK over the past 10 years, and to investigate the impact of reclassification using ICD-MM on the observed rates...
  32. pmc The effect of maternal age and planned place of birth on intrapartum outcomes in healthy women with straightforward pregnancies: secondary analysis of the Birthplace national prospective cohort study
    Yangmei Li
    Policy Research Unit in Maternal Health and Care, National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK
    BMJ Open 4:e004026. 2014
    ....
  33. pmc Cost effectiveness of alternative planned places of birth in woman at low risk of complications: evidence from the Birthplace in England national prospective cohort study
    Elizabeth Schroeder
    National Perinatal Epidemiology Unit, Department of Public Health, University of Oxford, Oxford OX3 7LF, UK
    BMJ 344:e2292. 2012
    ..To estimate the cost effectiveness of alternative planned places of birth...
  34. doi request reprint Towards optimising local reviews of severe incidents in maternity care: messages from a comparison of local and external reviews
    Anjali Shah
    National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK
    BMJ Qual Saf . 2016
    ..The aim of this project was to describe the methods used for conducting local reviews of care of women with severe maternal morbidity, and to compare lessons identified for future care through external and local reviews...
  35. pmc Severe sepsis in women with group B Streptococcus in pregnancy: an exploratory UK national case-control study
    Asli Kalin
    National Perinatal Epidemiology Unit NPEU, University of Oxford, Oxford, UK
    BMJ Open 5:e007976. 2015
    ..To estimate the incidence of severe maternal sepsis due to group B Streptococcus (GBS) in the UK, and to investigate the associated outcomes for mother and infant...
  36. pmc Pregnancy outcomes in liver and cardiothoracic transplant recipients: a UK national cohort study
    Olaa Mohamed-Ahmed
    National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, United Kingdom
    PLoS ONE 9:e89151. 2014
    ..The majority of studies reporting outcomes in transplant recipients have focused on women with kidney transplants, and have included retrospective, voluntary registries or single centre studies...
  37. ncbi request reprint How should randomised trials including multiple pregnancies be analysed?
    Simon Gates
    National Perinatal Epidemiology Unit, Institute of Health Sciences, Old Road, Oxford OX3 7LF, UK
    BJOG 111:213-9. 2004
    ..To compare the effects of four methods of analysis on the results of randomised controlled trials that recruit women with multiple pregnancies and measure outcomes on their babies...
  38. ncbi request reprint Recruitment to multicentre trials
    Simon Gates
    National Perinatal Epidemiology Unit, Institute of Health Sciences, Oxford, UK
    BJOG 111:3-5. 2004
  39. ncbi request reprint UK obstetric surveillance system uncovered
    Marian Knight
    UKOSS, National Perinatal Epidemiology Unit, University of Oxford
    RCM Midwives 8:38-9. 2005
  40. ncbi request reprint Acute obstetric emergency drill in England and Wales: a survey of practice
    Elizabeth R Anderson
    National Perinatal Epidemiology Unit, Oxford University, Oxford OX3 7LF, UK
    BJOG 112:372-5. 2005
    ..However, reliable methods to assess and thereby optimise methods are urgently required in order that women and their babies can realise the maximum benefit from these complex interventions...
  41. pmc Donor breast milk versus infant formula for preterm infants: systematic review and meta-analysis
    Catherine A Boyd
    National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Headington, Oxford OX3 7LF, UK
    Arch Dis Child Fetal Neonatal Ed 92:F169-75. 2007
    ..The main outcomes were death, necrotising enterocolitis (NEC), infection, growth and development...
  42. ncbi request reprint Surgical techniques used during caesarean section operations: results of a national survey of practice in the UK
    Lucy Tully
    National Perinatal Epidemiology Unit, Institute of Health Sciences, Old Road, Oxfrod OX3 7LF, UK
    Eur J Obstet Gynecol Reprod Biol 102:120-6. 2002
    ..To determine what surgical techniques are used by obstetricians in the UK for elective and emergency caesarean section operations...
  43. doi request reprint Temperature control during therapeutic moderate whole-body hypothermia for neonatal encephalopathy
    B Strohm
    National Perinatal Epidemiology Unit, Old Road Campus, Headington, Oxford, UK
    Arch Dis Child Fetal Neonatal Ed 95:F373-5. 2010
    ..The precision of temperature control achieved in clinical practice during therapeutic hypothermia in neonates has not been described...
  44. doi request reprint Subcutaneous fat necrosis after moderate therapeutic hypothermia in neonates
    Brenda Strohm
    National Perinatal Epidemiology Unit, Oxford, UK
    Pediatrics 128:e450-2. 2011
    ..Blood calcium levels need to be monitored in affected infants...