Kailash P Bhatia

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Psychogenic tremor and related disorders
    Kailash P Bhatia
    Sobell Department of Motor Neuroscience, Institute of Neurology UCL, Queen Square, London WC1N 3BG, UK
    J Neurol 254:569-74. 2007
  2. pmc Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
    Daniel G Healy
    Department of Clinical Neurosciences, Institute of Neurology, University College London, London, UK
    Lancet Neurol 7:583-90. 2008
  3. pmc The cervical dystonia impact profile (CDIP-58): can a Rasch developed patient reported outcome measure satisfy traditional psychometric criteria?
    Stefan J Cano
    Neurological Outcome Measures Unit, Institute of Neurology, University College London, Queen Square, London, UK
    Health Qual Life Outcomes 6:58. 2008
  4. ncbi request reprint Theta burst stimulation of the human motor cortex
    Ying Zu Huang
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Neuron 45:201-6. 2005
  5. ncbi request reprint Cortical evoked potentials from pallidal stimulation in patients with primary generalized dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:265-73. 2008
  6. ncbi request reprint Prolonged cortical silent period but normal sensorimotor plasticity in spinocerebellar ataxia 6
    James T H Teo
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
    Mov Disord 23:378-85. 2008
  7. ncbi request reprint Pallidal stimulation modifies after-effects of paired associative stimulation on motor cortex excitability in primary generalised dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Box 146 8 11 Queen Square, London WC1N 3BG, UK
    Exp Neurol 206:80-5. 2007
  8. doi request reprint Patients with primary cervical dystonia have evidence of discrete deficits in praxis
    Britt Sofie Hoffland
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, UCL, London, UK
    J Neurol Neurosurg Psychiatry 82:615-9. 2011
  9. ncbi request reprint Early-onset absence epilepsy and paroxysmal dyskinesia
    Renzo Guerrini
    Neurosciences Unit, Great Ormond Street Hospital for Sick Children and Institute of Child Health, University College London, London, England
    Epilepsia 43:1224-9. 2002
  10. ncbi request reprint NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach
    Daniel G Healy
    Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
    Mov Disord 21:1960-3. 2006

Collaborators

Detail Information

Publications68

  1. ncbi request reprint Psychogenic tremor and related disorders
    Kailash P Bhatia
    Sobell Department of Motor Neuroscience, Institute of Neurology UCL, Queen Square, London WC1N 3BG, UK
    J Neurol 254:569-74. 2007
    ..Prognosis, however, is relatively poor particularly if the condition has persisted for over a year and in the long-term up to 80-90% of patients continue to have abnormal movements...
  2. pmc Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
    Daniel G Healy
    Department of Clinical Neurosciences, Institute of Neurology, University College London, London, UK
    Lancet Neurol 7:583-90. 2008
    ..LRRK2-associated PD be distinguished from idiopathic PD; which mutations in LRRK2 are pathogenic; and what is the age-specific cumulative risk of PD for individuals who inherit or are at risk of inheriting a deleterious mutation in LRRK2?..
  3. pmc The cervical dystonia impact profile (CDIP-58): can a Rasch developed patient reported outcome measure satisfy traditional psychometric criteria?
    Stefan J Cano
    Neurological Outcome Measures Unit, Institute of Neurology, University College London, Queen Square, London, UK
    Health Qual Life Outcomes 6:58. 2008
    ....
  4. ncbi request reprint Theta burst stimulation of the human motor cortex
    Ying Zu Huang
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Neuron 45:201-6. 2005
    ....
  5. ncbi request reprint Cortical evoked potentials from pallidal stimulation in patients with primary generalized dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:265-73. 2008
    ..Because the EP is larger and more consistently present with stimulation of posteroventral GPi than GPe, it may provide a physiological tool to identify contacts within the optimal surgical target...
  6. ncbi request reprint Prolonged cortical silent period but normal sensorimotor plasticity in spinocerebellar ataxia 6
    James T H Teo
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
    Mov Disord 23:378-85. 2008
    ..A prolonged CSP in SCA6 just like in other cerebellar atrophies would suggest that this neurophysiological change typifies cerebellar dysfunction...
  7. ncbi request reprint Pallidal stimulation modifies after-effects of paired associative stimulation on motor cortex excitability in primary generalised dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Box 146 8 11 Queen Square, London WC1N 3BG, UK
    Exp Neurol 206:80-5. 2007
    ..To determine the effect of globus pallidus internus (GPi) deep brain stimulation (DBS) on motor cortex plasticity in patients with primary generalised dystonia...
  8. doi request reprint Patients with primary cervical dystonia have evidence of discrete deficits in praxis
    Britt Sofie Hoffland
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, UCL, London, UK
    J Neurol Neurosurg Psychiatry 82:615-9. 2011
    ..The aim of this study was to use a battery of tests of praxis, based on those tests used in routine clinical examination, to uncover evidence of higher motor dysfunction in patients with primary cervical dystonia...
  9. ncbi request reprint Early-onset absence epilepsy and paroxysmal dyskinesia
    Renzo Guerrini
    Neurosciences Unit, Great Ormond Street Hospital for Sick Children and Institute of Child Health, University College London, London, England
    Epilepsia 43:1224-9. 2002
    ..To report on the association of childhood absence epilepsy and paroxysmal dyskinesia (PD)...
  10. ncbi request reprint NR4A2 genetic variation in sporadic Parkinson's disease: a genewide approach
    Daniel G Healy
    Department of Molecular Neuroscience, Institute of Neurology, London, United Kingdom
    Mov Disord 21:1960-3. 2006
    ..Here, we use a haplotype-tagging approach in 802 PD patients and 784 controls and demonstrate that common genetic variation, including NR4A2 haplotypes, does not influence the risk of PD in the Caucasian population...
  11. ncbi request reprint Secondary nonresponsiveness to botulinum toxin A in cervical dystonia: the role of electromyogram-guided injections, botulinum toxin A antibody assay, and the extensor digitorum brevis test
    Carla Cordivari
    Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom
    Mov Disord 21:1737-41. 2006
    ..In those patients where the EDB test does not demonstrate resistance to BTXA, a reexamination of the patients and carefully placed injections under EMG guidance may improve results...
  12. doi request reprint Tremor--some controversial aspects
    Niall P Quinn
    Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 26:18-23. 2011
    ..In addition, the notion of a separate disorder of benign tremulous parkinsonism (BTP) has been debated. This article gives a selective viewpoint on some areas of uncertainty and controversy in tremor...
  13. ncbi request reprint Different patterns of electrophysiological deficits in manifesting and non-manifesting carriers of the DYT1 gene mutation
    Mark J Edwards
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Brain 126:2074-80. 2003
    ..This is consistent with the hypothesis that additional environmental/genetic insults may be needed to reveal clinical symptoms in DYT1 gene carriers...
  14. pmc Abnormal motor cortex plasticity in premanifest and very early manifest Huntington disease
    Michael Orth
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, UK
    J Neurol Neurosurg Psychiatry 81:267-70. 2010
    ....
  15. ncbi request reprint Patients with adult-onset dystonic tremor resembling parkinsonian tremor have scans without evidence of dopaminergic deficit (SWEDDs)
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom
    Mov Disord 22:2210-5. 2007
    ..Among patients suspected of PD, dystonic tremor may be one cause of SWEDDs (Scans Without Evidence of Dopaminergic Deficit)...
  16. ncbi request reprint Paroxysmal dyskinesia with interictal myoclonus and dystonia: a report of two cases
    Elisa De Grandis
    Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Parkinsonism Relat Disord 14:250-2. 2008
    ..This previously unreported association highlights the heterogeneity of paroxysmal movement disorders...
  17. ncbi request reprint Hyperthyroidism exaggerating parkinsonian tremor: a clinical lesson
    Hee Tae Kim
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, UCL, Queen Square, London WC1N 3BG, UK
    Parkinsonism Relat Disord 11:331-2. 2005
    ..This case report highlights that thyroid dysfunction should be considered in the differential diagnosis of aggravated tremor in Parkinson's disease which seems refractory to increased dosages of anti-parkinsonian drugs...
  18. ncbi request reprint A common LRRK2 mutation in idiopathic Parkinson's disease
    William P Gilks
    Department of Molecular Neuroscience, Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
    Lancet 365:415-6. 2005
    ..We suggest that testing for this mutation will be important in the management and genetic counselling of patients with Parkinson's disease...
  19. doi request reprint Complicated recessive dystonia parkinsonism syndromes
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom
    Mov Disord 24:490-9. 2009
    ..We concentrate on PANK2-, PLA2G6-, ATP13A2-, FBX07, TAF1-, and PRKRA-associated neurodegeneration. Parkin, PINK1, and DJ-1 are also briefly reviewed...
  20. ncbi request reprint The Huntington's disease-like syndromes: what to consider in patients with a negative Huntington's disease gene test
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders at the Institute of Neurology, University College London, Queen Square, London, UK
    Nat Clin Pract Neurol 3:517-25. 2007
    ....
  21. ncbi request reprint Secondary generalized dystonia without basal ganglia damage
    Robert K Mahapatra
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Parkinsonism Relat Disord 11:121-3. 2005
    ..This case adds to the small number of previously reported cases with secondary dystonia seemingly due to cortical rather than subcortical damage...
  22. ncbi request reprint Abnormalities in motor cortical plasticity differentiate manifesting and nonmanifesting DYT1 carriers
    Mark J Edwards
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, UCL, Queen Square, London, United Kingdom
    Mov Disord 21:2181-6. 2006
    ....
  23. ncbi request reprint Changes in blink reflex excitability after globus pallidus internus stimulation for dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 21:1650-5. 2006
    ..We conclude that GPi DBS for PTD results in functional reorganization of the nervous system, which includes a long-term increase in brainstem inhibition...
  24. ncbi request reprint The phenomenon of disproportionate antecollis in Parkinson's disease and multiple system atrophy
    Bart P C van de Warrenburg
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 22:2325-31. 2007
    ..However, a primary but yet unexplained neck extensor myopathy still remains the alternative possibility and longitudinal studies are necessary to settle this issue...
  25. ncbi request reprint Slowly progressive cerebellar ataxia and cervical dystonia: clinical presentation of a new form of spinocerebellar ataxia?
    Mikko Kuoppamaki
    National Hospital for Neurology and Neurosurgery, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 18:200-6. 2003
    ..We propose that this rare phenotype manifesting as a combination of cerebellar ataxia and cervical dystonia may represent one or more new, as yet uncharacterized, genotypes of inherited young-onset spinocerebellar ataxia...
  26. pmc The syndrome of (predominantly cervical) dystonia and cerebellar ataxia: new cases indicate a distinct but heterogeneous entity
    Bart P C van de Warrenburg
    J Neurol Neurosurg Psychiatry 78:774-5. 2007
  27. pmc Pisa syndrome after unilateral pallidotomy in Parkinson's disease: an unrecognised, delayed adverse event?
    Bart P C van de Warrenburg
    J Neurol Neurosurg Psychiatry 78:329-30. 2007
  28. ncbi request reprint The entity of young onset primary cervical dystonia
    Vasiliki Koukouni
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 22:843-7. 2007
    ..74% responded favorably to botulinum toxin injections, whereas none of the 13 patients treated with L-Dopa preparations had a beneficial response. The distinctive features of this entity are discussed...
  29. doi request reprint Cortical excitability is abnormal in patients with the "fixed dystonia" syndrome
    Laura Avanzino
    Sobell Department of Motor Neuroscience, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 23:646-52. 2008
    ..SAI and LAI did not significantly differ between the three groups. The abnormal cortical excitability observed in FD might represent an underlying trait predisposing to different clinical forms of dystonia...
  30. ncbi request reprint The entity of jaw tremor and dystonia
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 22:1491-5. 2007
    ..Jaw tremor in the context of dystonia is not well recognized...
  31. ncbi request reprint The natural history of Unverricht-Lundborg disease: a report of eight genetically proven cases
    Nee K Chew
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:107-13. 2008
    ..The clinical phenotypes associated with ULD are more diverse than previously recognized and even though the long term functional outcome and survival have improved, the overall efficacy of antimyoclonic drugs remains unsatisfactory...
  32. ncbi request reprint Botulinum toxin A may be efficacious as treatment for jaw tremor in Parkinson's disease
    Susanne A Schneider
    Sobell Department of Motorneuron Disease and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 21:1722-4. 2006
    ..There was an excellent response in all without side effects. BTX injections into the masseter may effectively improve jaw tremor and be useful in PD and other conditions...
  33. ncbi request reprint Atypical movement disorders in antiphospholipid syndrome
    Davide Martino
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 21:944-9. 2006
    ..Movement disorders in APS seem more clinically heterogeneous than previously thought. Oral anticoagulation should be considered in the treatment of movement disorders associated with APS...
  34. ncbi request reprint Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease
    Maria Bozi
    Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 18:1545-7. 2003
    ..Over time, symptoms occurred with minimal exercise. We conclude that PED can rarely be the first and only feature of PD...
  35. ncbi request reprint Patients with focal arm dystonia have increased sensitivity to slow-frequency repetitive TMS of the dorsal premotor cortex
    Hartwig R Siebner
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, UK
    Brain 126:2710-25. 2003
    ..Since the greater effects of premotor rTMS were not related to any differences in task performance, increased responsiveness of the motor system to rTMS reveals a physiological trait that characterizes patients with focal arm dystonia...
  36. ncbi request reprint Modulation of cortical activity by repetitive transcranial magnetic stimulation (rTMS): a review of functional imaging studies and the potential use in dystonia
    Sasa R Filipovic
    Sobell Department of Motor Neuroscience and Movement Disorders, London, United Kingdom
    Adv Neurol 94:45-52. 2004
  37. ncbi request reprint Myoclonus-dystonia syndrome: epsilon-sarcoglycan mutations and phenotype
    Friedrich Asmus
    Neurologische Klinik Grosshadern, Ludwig Maximilians Universitat, Munich, Germany
    Ann Neurol 52:489-92. 2002
    ..Six novel and one previously known heterozygous SGCE mutations were identified. SGCE deficiency seems to be the common pathogenetic mechanism in myoclonus-dystonia syndrome...
  38. ncbi request reprint Clinical features of the geste antagoniste in cervical dystonia
    Sasa R Filipovic
    Burden Neurological Institute, Departments of Neurology and Neuropsychiatry, Frenchay Hospital, Bristol, United Kingdom
    Adv Neurol 94:191-201. 2004
  39. ncbi request reprint One-Hz repetitive transcranial magnetic stimulation of the premotor cortex alters reciprocal inhibition in DYT1 dystonia
    Ying Zu Huang
    The Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London, United Kingdom
    Mov Disord 19:54-9. 2004
    ..These findings make a case for further exploring rTMS as a tool to modulate abnormal cortical and spinal excitability in individuals with dystonia and even as a potential form of treatment for dystonic symptoms...
  40. ncbi request reprint Abnormal cortical and spinal inhibition in paroxysmal kinesigenic dyskinesia
    Pablo Mir
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Brain 128:291-9. 2005
    ....
  41. ncbi request reprint Temporal discrimination of two passive movements in humans: a new psychophysical approach to assessing kinaesthesia
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Italy
    Exp Brain Res 166:184-9. 2005
    ..These results suggest that muscle, and in part cutaneous, afferents contribute to temporal discrimination of a dual movement. The technique may provide a useful way of measuring temporal discrimination of kinaesthetic inputs in humans...
  42. ncbi request reprint Alteration of central motor excitability in a patient with hemimasticatory spasm after treatment with botulinum toxin injections
    Pablo Mir
    Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 21:73-8. 2006
    ..These changes can be altered by successful treatment with botulinum toxin...
  43. ncbi request reprint Antibody-induced botulinum toxin therapy failure: can it be overcome by increased botulinum toxin doses?
    Dirk Dressler
    Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK
    Eur Neurol 47:118-21. 2002
    ....
  44. ncbi request reprint UCHL-1 is not a Parkinson's disease susceptibility gene
    Daniel G Healy
    Department of Molecular Neuroscience, Institute of Neurology, University College London, London, United Kingdom
    Ann Neurol 59:627-33. 2006
    ..The strongest evidence comes from a meta-analysis of small studies that reported the S18Y polymorphism as protective against PD, after pooling studies of white and Asian subjects. Here, we present data that challenge this association...
  45. ncbi request reprint Intracortical inhibition is reduced in a patient with a lesion in the posterolateral thalamus
    Alexander Munchau
    Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
    Mov Disord 17:208-12. 2002
    ....
  46. ncbi request reprint Parkin disease: a phenotypic study of a large case series
    Naheed L Khan
    Department of Molecular Pathogenesis, Royal Free Hospital and University College Medical School, London, UK
    Brain 126:1279-92. 2003
    ..Some relatives carrying a single parkin mutation without extrapyramidal symptoms or signs also had psychiatric symptoms that might be related to their carrier status...
  47. ncbi request reprint Further case of paroxysmal exercise-induced dystonia and some insights into pathogenesis
    Michael H Barnett
    National Hospital for Neurology and Neurosurgery, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 17:1386-7. 2002
    ..This finding lends support to the hypothesis that increased dopaminergic transmission contributes to the clinical features of the hyperkinetic movement disorders...
  48. ncbi request reprint Progressive delayed-onset dystonia after cerebral anoxic insult in adults
    Mikko Kuoppamaki
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 17:1345-9. 2002
    ..We hypothesize that anoxia-induced excitotoxicity resulting in mitochondrial dysfunction and subsequent apoptosis may explain, at least partly, the delayed-onset and progressive extrapyramidal syndromes seen in these patients...
  49. doi request reprint Fragile X syndrome associated with tic disorders
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:1108-12. 2008
    ..We suggest considering fragile X syndrome in GTS complicated by co-morbidity with late onset of atypical tics, in particular when learning disability and dysmorphic features are present...
  50. doi request reprint Antineuronal antibodies in Parkinson's disease
    Bart P C van de Warrenburg
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 23:958-63. 2008
    ..We conclude that ANAs do not play a role in the majority of patients with IPD, but might be relevant in the pathogenesis of IPD with atypical features...
  51. ncbi request reprint Genetic and clinical heterogeneity in paroxysmal kinesigenic dyskinesia: evidence for a third EKD gene
    Sian D Spacey
    Department of Molecular Pathogenesis, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 17:717-25. 2002
    ..This study attempts to clarify the relationship of adolescent and infantile seizures to PKD and provides evidence that PKD is both genetically and clinically heterogeneous...
  52. ncbi request reprint Descending control of muscles in patients with cervical dystonia
    Marina A J Tijssen
    Sobell Department of Neurophysiology, The Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 17:493-500. 2002
    ..The pattern of coherence between the EMG in different neck muscles may provide a means of identifying leading dystonic muscles, especially in patients with complex cervical dystonia...
  53. ncbi request reprint Temporal discrimination of two passive movements in writer's cramp
    Michele Tinazzi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, Italy
    Mov Disord 21:1131-5. 2006
    ..We conclude that temporal processing of muscle and cutaneous afferents is differentially affected in focal hand dystonia...
  54. ncbi request reprint The spectrum of orolingual tremor--a proposed classification system
    Monty A Silverdale
    Movement Disorders Center, Toronto Western Hospital, Toronto, Ontario, Canada
    Mov Disord 23:159-67. 2008
    ..We also present cases of orolingual tremor and include these cases in the classification system...
  55. ncbi request reprint Choreic syndrome and coeliac disease: a hitherto unrecognised association
    Anthony C Pereira
    Sobell Dept of Motor Neuroscience and Movement Disorders, Institute of Neurology, United Kingdom
    Mov Disord 19:478-82. 2004
    ..Unexpectedly, most of these patients showed a notable improvement in their motor symptoms after the introduction of a gluten-free diet...
  56. ncbi request reprint Adult-onset primary lower limb dystonia
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 21:767-71. 2006
    ..In this series of patients, the diagnosis was often not recognized, leading to extensive and unnecessary testing and treatment and emphasizing the need for wider recognition...
  57. ncbi request reprint Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data
    Naheed L Khan
    Department of Molecular Neuroscience, Institute of Neurology, London, UK
    Brain 128:2786-96. 2005
    ....
  58. ncbi request reprint Corticobasal degeneration
    Robert K Mahapatra
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Lancet Neurol 3:736-43. 2004
    ..Although definitive diagnosis of corticobasal degeneration can only be made at post-mortem examination, recent advances in imaging can assist the clinician with diagnosis. Treatment options remain limited and mostly address symptoms...
  59. ncbi request reprint Adult-onset generalized dystonia due to a mutation in the neuroferritinopathy gene
    Pablo Mir
    Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 20:243-5. 2005
    ..Neuroferritinopathy appears to be a rare disorder; hence, there is a need to report new cases to further our understanding of the clinical phenotype, diagnostic challenges, the course of the condition and imaging characteristics...
  60. ncbi request reprint Defective temporal discrimination of passive movements in Parkinson's disease
    Mirta Fiorio
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Neurologia Riabilitativa, Universita di Verona, and Unità Operativa Neurologia Ospedale Civile Borgo Trento, Verona, Italy
    Neurosci Lett 417:312-5. 2007
    ..Results showed that thresholds were significantly higher in PD patients than in control subjects for both FCR and FDI muscle, thus demonstrating for the first time that temporal proprioceptive processing is altered in PD...
  61. ncbi request reprint Mental rotation of body parts and non-corporeal objects in patients with idiopathic cervical dystonia
    Mirta Fiorio
    Department of Neurological and Vision Sciences, Section of Rehabilitative Neurology, University of Verona, Strada Le Grazie 8, 37134 Verona, Italy
    Neuropsychologia 45:2346-54. 2007
    ....
  62. ncbi request reprint Persisting hyperekplexia after idiopathic, self-limiting brainstem encephalopathy
    Bart P C van de Warrenburg
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 22:1017-20. 2007
    ..Trismus was the presenting feature, but she later developed hyperekplexia. Although most brainstem features resolved spontaneously, the hyperekplexia has persisted...
  63. ncbi request reprint Adult-onset tic disorder, motor stereotypies, and behavioural disturbance associated with antibasal ganglia antibodies
    Mark J Edwards
    Sobell Department of Movement Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London, United Kingdom
    Mov Disord 19:1190-6. 2004
    ..We suggest that there might be a causal relationship between ABGA and the clinical syndrome in these cases and that ABGA should be considered as a possible etiology for adult-onset tics...
  64. ncbi request reprint The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism
    Daniel G Healy
    Department of Molecular Neuroscience, Institute of Neurology, University College London, London, United Kingdom
    Ann Neurol 56:329-35. 2004
    ....
  65. ncbi request reprint Natural history and syndromic associations of orthostatic tremor: a review of 41 patients
    Willibald Gerschlager
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 19:788-95. 2004
    ..OT may not be a discrete disorder as commonly believed and associated features like parkinsonism present in nearly 25% of cases. Dopaminergic dysfunction may have a role in the pathophysiology of this disorder...
  66. ncbi request reprint Blepharospasm and limb dystonia caused by Mohr-Tranebjaerg syndrome with a novel splice-site mutation in the deafness/dystonia peptide gene
    Hee T Kim
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 22:1328-31. 2007
    ..This case, and a review of previously reported cases, highlights a variety of potential diagnostic pitfalls in this condition...
  67. ncbi request reprint Primary lateral sclerosis mimicking atypical parkinsonism
    Ibrahim M Norlinah
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 22:2057-62. 2007
    ..However, the absence of fatiguing and decrement on repeated finger/foot tapping should help to distinguish these patients from the true atypical parkinsonian syndromes...
  68. doi request reprint Dystonia in the Woodhouse Sakati syndrome: A new family and literature review
    Susanne A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:592-6. 2008
    ..We summarize findings from pervious cases with particular focus on neurological and movement disorder features...