Affiliation: University of East Anglia
- TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3A Amour
School of Biological Sciences, University of East Anglia, Norwich, UK
FEBS Lett 435:39-44. 1998..These results suggest that TIMP-3, unlike the other TIMPs, may be important in the modulation of pathological events in which TNF-alpha secretion is involved...
- Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2W R English
School of Biological Sciences, University of East Anglia, University Plain, Norwich, Norfolk NR4 7TJ, United Kingdom
J Biol Chem 275:14046-55. 2000..MT4-MMP was detected by Western blot in monocyte/macrophage cell lines which in combination with its fibrinolytic and TNFalpha-converting activity suggests a role in inflammation...