K G Alberti
Affiliation: University of Newcastle
- Have we got the new diagnostic criteria for diabetes and impaired glucose states right? AlmostK George M M Alberti
Department of Diabetes, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
Curr Diab Rep 2:1-2. 2002
- The metabolic syndrome: time to reflectK George M M Alberti
Mint Wing, St Mary s Hospital, Praed Street, London W2 1NY, UK
Curr Diab Rep 6:259-61. 2006
- Partnering with governments and other institutions: driving change in diabetes careK G M M Alberti
School of Clinical Medical Science Diabetes, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
Int J Clin Pract Suppl . 2007..It is now critical to maintain this momentum and use the growing body of compelling evidence to educate, inform and deliver a long-term, lasting impact on patient and public health worldwide...
- Prevention of type 2 diabetes in adults with impaired glucose tolerance: the European Diabetes Prevention RCT in Newcastle upon Tyne, UKLinda Penn
Public Health Research Programme, Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
BMC Public Health 9:342. 2009..In the Newcastle arm of this study (EDIPS-Newcastle), we tested the hypothesis that T2D can be prevented by lifestyle intervention and explored secondary outcomes in relation to diabetes incidence...
- Impaired glucose tolerance: what are the clinical implications?K G Alberti
Human Diabetes and Metabolism Research Centre, School of Clinical Medical Sciences, Department of Medicine, The Medical School, Framlington, Newcastle upon Tyne, UK
Diabetes Res Clin Pract 40:S3-8. 1998..IGT can be treated and this may prevent or delay progression to type 2 diabetes, though the effect of treatment on the risk of CVD is unknown...
- Should we dump the metabolic syndrome? NoK G M M Alberti
Department of Endocrinology and Metabolism, St Mary s Hospital and Imperial College, London
BMJ 336:641. 2008
- International Diabetes Federation: a consensus on Type 2 diabetes preventionK G M M Alberti
Department of Endocrinology and Metabolic Medicine, St Mary s Hospital, London, UK
Diabet Med 24:451-63. 2007..The IDF plan for prevention of Type 2 diabetes is based on controlling modifiable risk factors and can be divided into two target groups: People at high risk of developing Type 2 diabetes. The entire population...
- Screening and diagnosis of prediabetes: where are we headed?K G M M Alberti
Department of Endocrinology and Metabolic Medicine, Imperial College, St Mary s Hospital, London, UK
Diabetes Obes Metab 9:12-6. 2007..Fasting plasma glucose measurement cannot diagnose IGT; the preferred definite test for diagnosis is oral glucose tolerance testing...
- A comparison of proxy measures of abdominal obesity in Chinese, European and South Asian adultsS Patel
Department of Epidemiology and Public Health, Human Diabetes and Metabolism Research Centre, University of Newcastle, Newcastle upon Tyne, UK
Diabet Med 16:853-60. 1999....
- Hypertension prevalence and care in an urban and rural area of TanzaniaR Edwards
Department of Epidemiology and Public Health, School of Health Sciences, The Medical School, University of Newcastle upon Tyne, UK
J Hypertens 18:145-52. 2000..To describe the prevalence, detection, treatment and control of hypertension in an urban and rural area of Tanzania...
- Serum true insulin concentration and the risk of clinical non-insulin dependent diabetes during long-term follow-upI J Perry
Department of Primary Care and Population Sciences, The Royal Free Hospital School of Medicine, London, UK
Int J Epidemiol 28:735-41. 1999..Using a specific assay, we have addressed the hypothesis that an elevation of serum true insulin concentration, reflecting insulin resistance, is an early event in the pathogenesis of NIDDM...
- Age specific prevalence of impairment and disability relating to hemiplegic stroke in the Hai District of northern Tanzania. Adult Morbidity and Mortality ProjectR W Walker
Department of Medicine, North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, UK
J Neurol Neurosurg Psychiatry 68:744-9. 2000..To determine the age specific prevalence of impairment and disability relating to hemiplegic stroke in one rural area of Tanzania...
- Acute effects on insulin sensitivity and diurnal metabolic profiles of a high-sucrose compared with a high-starch dietM E Daly
Human Nutrition Research Centre, the Department of Biological and Nutritional Sciences, University of Newcastle upon Tyne, United Kingdom
Am J Clin Nutr 67:1186-96. 1998..001). Plasma fatty acid concentrations showed a late postprandial rise with the sucrose-rich diet relative to the starch-rich diet, which was mirrored with a fractionally later peak in triacylglycerol concentrations...
- Randomised controlled trial evaluating the effectiveness of behavioural interventions to modify cardiovascular risk factors in men and women with impaired glucose tolerance: outcomes at 6 monthsJ C Oldroyd
Department of Epidemiology and Public Health, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK
Diabetes Res Clin Pract 52:29-43. 2001..To evaluate the efficacy of interventions to promote a healthy diet and physical activity in people with impaired glucose tolerance (IGT)...
- Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes FederationK G M M Alberti
Department of Endocrinology and Metabolic Medicine, St Mary s Hospital, London, UK and International Diabetes Institute, Caulfield, Australia
Diabet Med 23:469-80. 2006..An additional aim was to highlight areas where more research into the MetS is needed...
- Lifecourse determinants of fasting and post-challenge glucose at age 50 years: the Newcastle Thousand Families StudyM S Pearce
School of Clinical Medical Sciences, University of Newcastle upon Tyne, UK
Eur J Epidemiol 20:915-23. 2005..Any effect of birth weight on later plasma glucose levels may be compounded by additional effects of adult body composition...
- Chronic non-communicable diseasesN Unwin
School of Population and Health Sciences, University of Newcastle upon Tyne, William Leech Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
Ann Trop Med Parasitol 100:455-64. 2006..As urbanization continues apace and populations age, investment in the prevention and control of NCD in low-and middle-income countries can no longer be ignored...
- Patterns of physical activity and relationship with risk markers for cardiovascular disease and diabetes in Indian, Pakistani, Bangladeshi and European adults in a UK populationLouise Hayes
Department of Epidemiology and Public Health, University of Newcastle upon Tyne, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH
J Public Health Med 24:170-8. 2002....
- A lifecourse study of risk for hyperinsulinaemia, dyslipidaemia and obesity (the central metabolic syndrome) at age 49-51 yearsL Parker
Paediatric and Lifecourse Epidemiology Research Group, University of Newcastle upon Tyne, Sir James Spence Institute of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, UK
Diabet Med 20:406-15. 2003..A central metabolic syndrome (CMS) has been identified comprising obesity, dyslipidaemia and insulin resistance. This study was designed to investigate determinants of risk for CMS...
- Stroke mortality in urban and rural Tanzania. Adult Morbidity and Mortality ProjectR W Walker
Department of Medicine, North Tyneside General Hospital, North Shields, Tyne and Wear, UK
Lancet 355:1684-7. 2000..We aimed to establish the contribution of cerebrovascular disease to all-cause mortality and cerebrovascular disease mortality rates in adults aged 15 years or more in one urban and two rural areas of Tanzania...
- Smoking and alcohol consumption in a UK Chinese populationM White
Department of Epidemiology and Public Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
Public Health 115:62-9. 2001..Patterns of health related behaviour should be tracked over time in ethnic minority populations to identify changes that pose risk to health and which deserve appropriate intervention...
- Octreotide treatment does not improve impaired glucose uptake in cirrhosisE Shmueli
Department of Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, England
Horm Metab Res 25:317-20. 1993..It was concluded that one week of lowering insulin levels does not reverse the insulin resistance of cirrhosis...
- Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and interventionN Unwin
Diabetes and Metabolism, School of Clinical Medical Sciences, University of New Castle, UK
Diabet Med 19:708-23. 2002..4. Life style interventions are highly effective in delaying or preventing the onset of diabetes in people with IGT and may reduce CVD and total mortality, but the latter requires formal testing...
- Microalbuminuria is more frequent in South Asian than in European origin populations: a comparative study in Newcastle, UKC M Fischbacher
Department of Epidemiology and Public Health, The Medical School, University of Newcastle upon Tyne, Newcastle, UK
Diabet Med 20:31-6. 2003..Coronary heart disease (CHD) mortality is 40-50% higher in UK South Asians compared with the whole population, for reasons that are incompletely understood...
- British South Asians aged 13-16 years have higher fasting glucose and insulin levels than EuropeansP H Whincup
Department of Community Health Sciences, St George s Hospital Medical School, London, UK
Diabet Med 22:1275-7. 2005..To examine whether plasma glucose, insulin resistance and markers of adiposity differed between British adolescents of South Asian and European origin...
- Metabolic syndrome and renal sodium handling in three ethnic groups living in EnglandA Barbato
Department of Community Health Sciences, St George s Hospital Medical School, Cranmer Terrace, SW17 0RE, London, UK
Diabetologia 47:40-6. 2004..Our study examined whether this association also exists in other ethnic groups with different prevalences of insulin resistance and associated metabolic abnormalities...
- Fatty acid metabolism in hepatocytes cultured with hypolipidaemic drugs. Role of carnitineP Gerondaes
Department of Medicine, University of Newcastle upon Tyne
Biochem J 253:161-7. 1988..It is concluded that the increase in hepatic carnitine that occurs in vivo after fibrate feeding probably plays the major role in the changes in partitioning of fatty acid between beta-oxidation and esterification...
- Hormonal and metabolic profiles in subjects with obstructive sleep apnea syndrome and the acute effects of nasal continuous positive airway pressure (CPAP) treatmentB G Cooper
Department of Medicine, University of Newcastle upon Tyne, England
Sleep 18:172-9. 1995..Because growth hormone has a lipolytic action, the results suggest that suppression of secretion of growth hormone in untreated OSA results in impaired lipolysis, which is rapidly reversed by nasal CPAP...
- Rural and urban differences in diabetes prevalence in Tanzania: the role of obesity, physical inactivity and urban livingT J Aspray
Department of Medicine, Medical School, University of Newcastle upon Tyne, NE2 4HH, UK
Trans R Soc Trop Med Hyg 94:637-44. 2000..The avoidance of obesity in the adult population is likely to prevent increases in diabetes incidence in this population...
- The metabolic syndrome: in need of a global mission statementA J Cameron
Department of Epidemiology and Clinical Diabetes, Baker IDI Heart and Diabetes Institute, Newcastle upon Tyne, UK
Diabet Med 26:306-9. 2009..Our aim was to construct a mission statement that outlines the value of the metabolic syndrome in clinical and public health settings...
- Alcohol consumption and the incidence of type II diabetesS G Wannamethee
Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
J Epidemiol Community Health 56:542-8. 2002..This study examines the relation between alcohol and type II diabetes and the possible mediating effects of HDL-cholesterol and serum insulin...
- The performance of the Rose angina questionnaire in South Asian and European origin populations: a comparative study in Newcastle, UKC M Fischbacher
Department of Epidemiology and Public Health, The Medical School, University of Newcastle upon Tyne, Newcastle NE2 4HH, UK
Int J Epidemiol 30:1009-16. 2001..We set out to assess the performance of the Rose angina questionnaire in UK South Asians compared with Europeans...
- The effect of high glucose and high insulin concentrations on pentose phosphate shunt enzymes and malic enzyme in cultured human endothelial cellsG C Hawthorne
Department of Medicine, Medical School, Newcastle upon Tyne, United Kingdom
Horm Metab Res 20:645-7. 1988..As a consequence fatty acid and cholesterol synthesis in the endothelial cell is unlikely to be altered in the presence of increased glucose or increased insulin...
- The lung as a target organ for thyroxineH Datta
Department of Medicine, Medical School, Newcastle upon Tyne, United Kingdom
Horm Metab Res 21:305-8. 1989..The implication is that oxidative metabolism of glucose was increased. This study provides the first unequivocal evidence that the mammalian lung is a target organ for thyroxine...
- Variable effects of the APOC3-482C > T variant on insulin, glucose and triglyceride concentrations in different ethnic groupsD M Waterworth
Centre for Cardiovascular Genetics, Department of Medicine, The Rayne Institute, University College, London, UK
Diabetologia 44:245-8. 2001..We evaluated the effect of this variant in different ethnic groups with different rates of Type II (non-insulin-dependent) diabetes mellitus and coronary heart disease...
- Blood pressure response to glucose potassium insulin therapy in patients with acute stroke with mild to moderate hyperglycaemiaJ F Scott
School of Clinical Medical Sciences, University of Newcastle-upon-Tyne, UK
J Neurol Neurosurg Psychiatry 70:401-4. 2001..The significant reduction of systolic blood pressure in acute stroke associated with GKI therapy was not associated with neurological deterioration and may have been beneficial...
- Point: impaired fasting glucose: The case for the new American Diabetes Association criterionJonathan E Shaw
Diabetes Care 29:1170-2. 2006
- Sleep-disordered breathing and type 2 diabetes: a report from the International Diabetes Federation Taskforce on Epidemiology and PreventionJonathan E Shaw
International Diabetes Institute, 250 Kooyong Road, Caulfield, Melbourne, VIC 3162, Australia
Diabetes Res Clin Pract 81:2-12. 2008....
- Life course determinants of insulin secretion and sensitivity at age 50 years: the Newcastle thousand families studyMark S Pearce
School of Clinical Medical Sciences, University of Newcastle upon Tyne, UK
Diabetes Metab Res Rev 22:118-25. 2006..This study investigated the proportion of variance in insulin secretion and resistance accounted for by factors operating at different stages of life using a cohort of all 1142 births in the city of Newcastle, UK in May and June 1947...
- The metabolic syndrome--a new worldwide definitionK George M M Alberti
Department of Endocrinology and Metabolism, St Marys Hospital, London W2 1NY, UK
Lancet 366:1059-62. 2005
- Mainstreaming the metabolic syndrome: a definitive definitionPaul Z Zimmet
Med J Aust 183:175-6. 2005..This new definition should assist both researchers and clinicians...
- Inhaled insulinStephanie A Amiel
BMJ 328:1215-6. 2004
- Cardio-diabetes alliancesClifford J Bailey
Diab Vasc Dis Res 4:6-7. 2007
- Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK)Christopher S Gray
School of Clinical Medical Sciences, University of Newcastle, Newcastle upon Tyne, UK
Lancet Neurol 6:397-406. 2007..We sought to determine whether treatment with glucose-potassium-insulin (GKI) infusions to maintain euglycaemia immediately after the acute event reduces death at 90 days...
- Introduction: Globalization and the non-communicable disease epidemicPaul Z Zimmet
International Diabetes Institute, 250 Kooyong Road, Caulfield 3162, Victoria, Australia
Obesity (Silver Spring) 14:1-3. 2006